Abstract：
:The effects of NO in its environment may vary considerably depending on various factors. This study shows oxidative mechanism of cellular membrane alterations, which is not associated with triggering of ONOOH generation but is induced by pure NO. Our investigation examined the influence of low concentration of NO (0.1; 0.2 mmol/l) on the qualitative changes of structure and dynamics of erythrocyte membrane. NO causes a statistically significant increase in membrane fluidity on different depths of lipid bilayer that is correlated with increase of lipids peroxidation. Statistically significant changes in the conformational state of cytoskeleton proteins were also detected. NO can be considered as a molecule responsible for determining rheological properties of erythrocytes membrane. Therefore, we propose that NO acts as pro-oxidant molecule at concentrations for which membrane appeared to be the first target before it entered the cytosol.
journal_name
Cell Biol Intjournal_title
Cell biology internationalauthors
Brzeszczynska J,Gwozdzinski Kdoi
10.1016/j.cellbi.2007.08.020subject
Has Abstractpub_date
2008-01-01 00:00:00pages
114-20issue
1eissn
1065-6995issn
1095-8355pii
S1065-6995(07)00218-1journal_volume
32pub_type
杂志文章abstract：:Conventional kinesin is an ATPase-active motor protein that is involved in the microtubule-dependent transport of cytoplasmic cargoes. The present paper provides a condensed overview on kinesin-1 and its motility generation outside a living cell. Moreover, it demonstrates that the neuron-specific kinesin KIF5A enables...
journal_title：Cell biology international
pub_type： 杂志文章,评审
doi：10.1016/j.cellbi.2007.12.001
更新日期：2008-05-01 00:00:00
abstract：:Previous trials performed in our laboratory have demonstrated that stainless steel corrosion products induced morphological changes in mice seminiferous cells. In this study the functional nature of the blood-testis barrier was investigated, in view of the extensive use of this metallic alloy in orthopaedic surgery. T...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1006/cbir.1995.1109
更新日期：1995-07-01 00:00:00
abstract：:Peritoneal dialysis (PD) is often used to treat patients with end stage renal disease, and its long-term complications include excessive inflammation and oxidative stress. Allograft inflammatory factor 1 (AIF-1), as a cytoplasmic protein, is originally identified from infiltrating macrophages, and it was associated wi...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.11115
更新日期：2019-05-01 00:00:00
abstract：:We describe a method to hold living cells in place that ordinarily do not adhere to glass coverslips. The method, developed for insect spermatocytes but with application to other cell types, consists of embedding cells in a fibrin clot that forms after the enzyme thrombin cleaves the blood protein fibrinogen. The meth...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2005.04.010
更新日期：2005-09-01 00:00:00
abstract：:Adult peripheral blood-derived cells are able to differentiate into a variety of cell types, including nerve cells, liver-like cells and epithelial cells. However, their differentiation into retina-like cells is controversial. In the present study, transdifferentiation potential of human adult peripheral blood mononuc...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1042/CBI20100146
更新日期：2011-06-01 00:00:00
abstract：:To characterize the cytoplasmic structure reorganization during plant meiosis, the male meiocytes of Althaea rosea (L.) Cavan were examined under the combination of light and electron microscopy. Light microscopic observation of the toluidine blue-stained thick resin sections of young anthers revealed that the meiocyt...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2007.12.006
更新日期：2008-04-01 00:00:00
abstract：:Conditioned medium (CM) (cell secretome) is a cocktail of growth factors, cytokines, and other soluble mediators secreted by cells into a culture medium. These growth factors are fundamental in many cellular processes such as cell growth, differentiation, and others and the composition of these factors is individual f...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.11317
更新日期：2020-05-01 00:00:00
abstract：:Peroxisomicine A1 (PA1) is a potential antineoplastic agent with high and selective toxicity toward peroxisomes of tumor cells. Pexophagy is a selective autophagy process that degrades damaged peroxisomes; this process has been studied mainly in methylotrophic yeasts. There are two main modes of pexophagy in yeast: ma...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.11280
更新日期：2020-03-01 00:00:00
abstract：:The aim of this study was to examine the effects of glafenine hydrochloride (a nonsteroidal anti-inflammatory drug) on proliferation, clonogenic activity, cell-cycle, migration, and the extracellular matrix protein tenascin of human aortic smooth muscle cells (haSMCs) and human endothelial cells (ECs) in vitro.HaSMCs ...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2003.09.001
更新日期：2003-01-01 00:00:00
abstract：:Growing evidence has shown that apelin/APJ system functions as a critical mediator of cardiac development as well as cardiovascular function. Here, we investigated the role of apelin in the cardiomyogenic differentiation of mesenchymal stem cells derived from Wharton's jelly of human umbilical cord in vitro. In this r...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.10581
更新日期：2016-05-01 00:00:00
abstract：:The plasticity of human and murine bone marrow mesenchymal stem cells (BMSCs) has been proven by their ability to trans-differentiate to multilineage cells, including germ cells. We have investigated ability of goat BMSCs to trans-differentiate to germ cells with extrinsic (e.g., retinoic acid [RA] and BMP4 signalling...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.10348
更新日期：2015-01-01 00:00:00
abstract：:In plastic and reconstructive field, it would be much beneficial to fabricate an engineered adipose tissue substitute allowing reliable and complete fat tissue regeneration. Tissue engineering chamber (TEC) holds the promise to optimize an adipogenic configuration that is efficacious as well as reproducible. A frequen...
journal_title：Cell biology international
pub_type： 杂志文章,评审
doi：10.1002/cbin.10731
更新日期：2017-04-01 00:00:00
abstract：:Human umbilical CD34(+) immature haematopoietic cells were rapidly and efficiently obtained from light density MNC (mononuclear cells) by MACS (magnetic cell sorting). An ex vivo expanded population of CD34(+) was cultured in serum-free medium supplemented with cytokines FL (flt3 ligand), SCF (stem cell factor) and TP...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1042/CBI20090493
更新日期：2011-01-01 00:00:00
abstract：:The number of the nucleoli in a CaCo-2 cell nucleus does not generally depend on the quantity of DNA in the nucleus, but nucleolar DNA content is directly proportional to total nuclear DNA. However, in multinucleolar cells (three or more nucleoli), the nucleolar DNA content increases after 96 h incubation in culture w...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2004.01.004
更新日期：2004-01-01 00:00:00
abstract：:Epidermis, a continuously renewing tissue, is maintained by stem cells that proliferate and replenish worn out or damaged cells in the tissue during life. Cultured epidermal stem cells have great potential in scientific research and clinical application. However, isolating a pure and viable population of epidermal ste...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2004.04.007
更新日期：2004-01-01 00:00:00
abstract：:In the presence of low density lipoprotein (LDL), Chlamydia pneumoniae induces macrophage-derived foam cell formation, a typical pathological feature of early atherosclerosis. However, its mechanism has not been fully understood. Peroxisome proliferator-activated receptors (PPARs) are key regulators of macrophage lipi...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2008.12.002
更新日期：2009-03-01 00:00:00
abstract：:A plant transformation and selection system has been developed utilizing a modified tubulin gene as a selectable marker. The vector constructs carrying a mutant alpha-tubulin gene from goosegrass conferring resistance to dinitroaniline herbicides were created for transformation of monocotyledonous and dicotyledonous p...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2007.11.012
更新日期：2008-05-01 00:00:00
abstract：:Zinc-finger E-box binding homeobox 1 (ZEB1) is a master regulator of epithelial-mesenchymal transition (EMT) and has been implicated in primary epithelial cancer biological processes, such as invasion and metastasis. However, the role of ZEB1 in progression of melanoma and cancer stem cells (CSCs) remains obscure. In ...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.10223
更新日期：2014-04-01 00:00:00
abstract：:Heat shock proteins (HSPs) are molecular chaperones involved in protein folding, assembly and transport, and which play critical roles in the regulation of cell growth, survival and differentiation. We set out to test the hypothesis that HSP27 protein is expressed in the human testes and its expression varies with the...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2008.07.009
更新日期：2008-10-01 00:00:00
abstract：:Cloning efficiency in mammalian systems remains low because reprogramming of donor cells is frequently incomplete. Nuclear factors in the oocyte are removed by enucleation, and this removal may adversely affect reprogramming efficiency. Here, we investigated the role of porcine oocyte nuclear factors during reprogramm...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.10554
更新日期：2016-02-01 00:00:00
abstract：:The induction and maintenance of immunologic tolerance at the feto-maternal interface is necessary for a successful pregnancy. The most accepted hypothesis for the mechanism underlying this tolerance is that pregnancy-induced foetal antigen-specific maternal T regulatory (T(reg) ) cells mediate maternal tolerance to t...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.10023
更新日期：2013-02-01 00:00:00
abstract：:The microbicidal capacity of the macrophage is frequently evaded by mycobacteria, leading to tuberculosis (TB). We investigated a number of parameters affecting the rate of growth of mycobacteria in human monocyte-derived macrophages (MDM). The results show a great deal of variation in the growth of both Mycobacterium...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1006/cbir.2000.0679
更新日期：2001-01-01 00:00:00
abstract：:The single-minded 2 gene (Sim2) plays a crucial role in the mental retardation of Down Syndrome (DS). To explore how Sim2 influences spatial memory, a DNA plasmid-encoding mouse Sim2 (mSim2) wrapped with liposome was bilaterally injected into the hippocampus of rats. The effect of overexpressing mSim2 on spatial learn...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2006.07.003
更新日期：2006-10-01 00:00:00
abstract：:Transforming growth factor β1 (TGFβ1) is a negative regulator of hematopoiesis, and yet, it is frequently found at the active sites of hematopoiesis. Here, we show for the first time that bone marrow-derived mononuclear cells (BM MNCs) secrete TGFβ1 in response to erythropoietin (EPO). We further show that human bone ...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.11437
更新日期：2020-11-01 00:00:00
abstract：:The formation of vertebrate skeletal muscles widely thought to be under the control of hierarchy of regulatory genes. MYF5 is one of the myogenic determination gene expressed in the developing mouse dermomyotome which control skeletal muscle differentiation. In the current work, we had obtained the cDNA sequence inclu...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.10124
更新日期：2013-09-01 00:00:00
abstract：:We analyzed the connection of changes in nucleus ploidy with changes in nucleolar apparatus of NIH 3T3 cells. The quantity of nucleoli does not depend on the quantity of nucleolar DNA, but instead depends on euploidy: the majority of euploid cells have 1-3 nucleoli. The quantity of DNA in the nucleolus is correlated w...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/s1065-6995(03)00158-6
更新日期：2003-01-01 00:00:00
abstract：:The cytosolic lipid droplets (cLDs) store excess intracellular lipids, and perilipin-2 is believed to protect cLDs from degradation. Here, we investigated the role of the small G-protein Arf1 and the proteasome in the fates of perilipin-2 and cLDs. In oleate-loaded cells, upon brefeldin A (BFA) treatment, perilipin-2 ...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1002/cbin.10547
更新日期：2016-02-01 00:00:00
abstract：:The first description of intrachromosomal fibers was made by Baranetzky in 1880. Since that time, a plethora of fibrillar substructures have been described inside the mitotic chromosomes, and published data indicate that chromosomes may be formed as a result of the hierarchical folding of chromatin fibers. In this rev...
journal_title：Cell biology international
pub_type： 杂志文章,评审
doi：10.1002/cbin.10672
更新日期：2016-11-01 00:00:00
abstract：:Mammalian cells in vivo frequently express primary cilia. Although some fully differentiated cell types rarely, if ever, express them, most do, indicating that they are regular cell organelles. Their expression can also be explored in vitro, where conditions--physical and chemical, intrinsic and extrinsic--permit expe...
journal_title：Cell biology international
pub_type： 杂志文章,评审
doi：10.1006/cbir.1996.0011
更新日期：1996-01-01 00:00:00
abstract：:To identify the molecular basis by which nonpermissive temperature (NPT) induces cell differentiation in Sertoli TTE3 cells harboring temperature-sensitive SV40 large T-antigen, we performed global scale microarray and computational gene network analyses. In TTE3 cells, inactivation of the large T-antigen by a NPT at ...
journal_title：Cell biology international
pub_type： 杂志文章
doi：10.1016/j.cellbi.2007.04.007
更新日期：2007-10-01 00:00:00
