Dexmedetomidine protects hepatic cells against oxygen-glucose deprivation/reperfusion injury via lncRNA CCAT1.

abstract：:A combination of in vivo UV light-induced crosslinking of nucleic acids to proteins and in vitro label transfer assay was applied to investigate specific interactions between AU-rich sequences (ARE) in the 3' UTR of lymphokine mRNAs and cytoplasmic AU-rich sequence element binding proteins (AUBP) in normal human lymph...

journal_title：Cell biology international

authors： Henics T,Nagy E,Rigby WF

更新日期：1995-09-01 00:00:00

abstract：:Transforming growth factor-β (TGF-β) is a potent inhibitor of the growth of normal mammary epithelial cells, and has a pleiotropic, context-dependent, concentration-dependent action. We found attenuation of TGF-β signalling in mammary adenoma carcinoma cells. Phosphorylation at the linker site of Smad2 occurred in a c...

journal_title：Cell biology international

authors： Sengupta S,Kundu S,Bhattacharyya A

更新日期：2013-05-01 00:00:00

abstract：:Insulin-like growth factor-1 (IGF-1) is a positive regulator in proliferation and differentiation of skeletal muscle cells, while myostatin (MSTN) is a member of transforming growth factor beta superfamily that acts as a negative regulator of skeletal muscle mass. The present study was performed to detail whether a co...

journal_title：Cell biology international

authors： Miyake M,Hayashi S,Sato T,Taketa Y,Watanabe K,Hayashi S,Tanaka S,Ohwada S,Aso H,Yamaguchi T

更新日期：2007-10-01 00:00:00

abstract：:The advent of scanning probe microscopy has introduced a powerful new method of probing the structural features of biological specimens. In this study, high resolution atomic force microscopy micrographs of single, isolated, cardiac myocytes are presented. Significantly, our images show not only the features to be exp...

journal_title：Cell biology international

authors： Davis JJ,Hill HA,Powell T

更新日期：2001-01-01 00:00:00

abstract：:Restriction Endonucleases (REs) may recognize, cleave and remove DNA from fixed chromatin producing specific chromosome banding patterns. However, the modifications produced in the chromatin fibre are not easy to evaluate and compare. The aim of the present investigation was to visualize differences resulting in the t...

journal_title：Cell biology international

authors： Gosálvez J,López-Fernández C,Fernández JL,Goyanes VJ,Buño I

更新日期：1996-03-01 00:00:00

abstract：:Introns of plant tubulin genes are useful molecular tools to study IME (Intron Mediated Enhancement of gene expression) and to define plant genetic and evolutionary relationships through ILP (Intron Length Polymorphism). Here we show that the intron present within the 5'UTR sequence of some rice beta-tubulin genes can...

journal_title：Cell biology international

authors： Breviario D,Gianì S,Ponzoni E,Mastromauro F,Morello L

更新日期：2008-05-01 00:00:00

abstract：:Although clinical data suggest remarkable promise for targeting programmed cell death protein-1 (PD-1) and ligand (PD-L1) signaling in non-small-cell lung cancer (NSCLC), it is still largely undetermined which subtype of patients will be responsive to checkpoint blockade. In the present study, we explored whether PD-L...

journal_title：Cell biology international

authors： Pan LN,Ma YF,Li Z,Hu JA,Xu ZH

更新日期：2020-12-15 00:00:00

abstract：:Epicatechin, a flavonoid belonging to the group of compounds collectively called catechins, have been reported to possess insulin-like properties. Besides their anti-diabetic properties, catechins also show growth inhibition. Since cytosolic pH (pHi) plays a role in cell proliferation and the Na/H exchanger (NHE) is t...

journal_title：Cell biology international

authors： Matteucci E,Rizvi SI,Giampietro O

更新日期：2001-01-01 00:00:00

abstract：:The neuropathology associated with Parkinson's disease (PD) is thought to involve excessive production of free radicals, dopamine autoxidation, defects in glutathione peroxidase expression, attenuated levels of reduced glutathione, altered calcium homeostasis, excitotoxicity and genetic defects in mitochondrial comple...

journal_title：Cell biology international

authors： González-Polo RA,Soler G,Rodríguezmartín A,Morán JM,Fuentes JM

更新日期：2004-01-01 00:00:00

abstract：:Cell therapy and regenerative medicine are potentially two of the most exciting aspects of the novel therapeutic methods currently under development. However, these treatments present a number of important biosafety issues, like the possible transmission of microorganisms to the recipients. The most common potential f...

journal_title：Cell biology international

authors： Cobo F,Cortés JL,Cabrera C,Nieto A,Concha A

更新日期：2007-09-01 00:00:00

abstract：:The purpose of the study was to examine mechanisms controlling cell cycle progression/arrest and differentiation of mouse C2C12 myoblasts exposed to long-chain saturated fatty acid salt, palmitate. Treatment of proliferating myoblasts with palmitate (0.1 mmol/l) markedly decreased myoblast number. Cyclin A and cyclin ...

journal_title：Cell biology international

authors： Grabiec K,Milewska M,Błaszczyk M,Gajewska M,Grzelkowska-Kowalczyk K

更新日期：2015-09-01 00:00:00

abstract：:Cell proliferation rates of diagnostic marrow aspirate cells of 21 children with Acute Lymphoblastic Leukaemia and 16 controls were compared using immunocytochemical labelling of PCNA and Ki-67 antigen as assessed by Confocal Laser Scanning Microscopy. The results showed an unexpected, highly significant degree of dis...

journal_title：Cell biology international

authors： Ball LM,Pope J,Howard CV,Eccles P,van Velzen D

更新日期：1994-09-01 00:00:00

abstract：:Disconnected interacting protein 2 (DIP2) is a highly conserved protein family among invertebrates and vertebrates, but its function remains unclear. In this paper, we summarized the conservation of gene sequences and protein domains of DIP2 family members and predicted that they may have a similar functional role in ...

journal_title：Cell biology international

authors： Ma J,Chen L,He XX,Wang YJ,Yu HL,He ZX,Zhang LQ,Zheng YW,Zhu XJ

更新日期：2019-04-01 00:00:00

abstract：:Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF-receptor derived peptide was active as a negative modulator of e...

journal_title：Cell biology international

authors： Willems J,Noppe W,Slegers H

更新日期：1995-11-01 00:00:00

abstract：:Recently, we reported that human PDB (placental decidua basalis) is an excellent source of MSCs (mesenchymal stem cells), meanwhile, PDB-MSCs could survive under hypoxia and serum deprivation. Herein, we investigated the proliferation, clonogentic efficiency, phenotypes, metabolic activity and cytokines secretion of P...

journal_title：Cell biology international

authors： Huang YC,Yang ZM,Jiang NG,Chen XH,Li XQ,Tan MY,Zhou KP,Tang L,Xie HQ,Deng L

更新日期：2010-01-27 00:00:00

abstract：:Non-small-cell carcinoma (NSCLC) is the most common cancer along with high mortality rate worldwide. In the present study, our data showed that lncRNA MAF BZIP Transcription Factor G Antisense RNA 1 (MAFG-AS1) was over-expressed in NSCLC tissues and cell lines. Overexpression of MAFG-AS1 promoted the migration, invasi...

journal_title：Cell biology international

authors： Jia YC,Wang JY,Liu YY,Li B,Guo H,Zang AM

更新日期：2019-04-01 00:00:00

abstract：:Kallikrein 14 (KLK14) is a serine protease linked to several pathologies including prostate cancer and positively correlates with Gleason score. Though KLK14 functioning in cancer is poorly understood, it has been implicated in HGF/Met signaling, given that KLK14 proteolytically inhibits HGF activator-inhibitor 1 (HAI...

journal_title：Cell biology international

authors： Solís-Calero C,Carvalho HF

更新日期：2017-11-01 00:00:00

abstract：:The aim of this study was to determine the polarization of macrophages in the tumor microenvironment, as well as the effect of soluble factors secreted from these polarized macrophages on etoposide-induced cancer cell apoptosis. We investigated the effect of soluble factors secreted from the supernatant of PC3 cells t...

journal_title：Cell biology international

authors： Malekghasemi S,Majidi J,Baradaran B,Aghebati-Maleki L

更新日期：2020-10-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is a serious global health problem. Recently, accumulating microRNA (miRNA) has emerged as crucial players in the development and progression of carcinomas including OSCC. Our study aimed to further investigate the roles of miR-140-5p in OSCC tumorigenesis and related molecular basi...

journal_title：Cell biology international

authors： Peng M,Pang C

更新日期：2019-08-08 00:00:00

abstract：:Protein composition and functional activity of various polysome subpopulations isolated from Vicia faba L. leaves and Triticum aestivum L. and Hordeum vulgare L. seedlings were studied. Membrane- and cytoskeleton-bound polysomes were more active in the wheat germ cell-free translational system than free polysomes. Sev...

journal_title：Cell biology international

authors： Klyachko N,Aksenova L,Dunaeva M,Kulikova A

更新日期：2000-01-01 00:00:00

abstract：:Low-temperature stress during microspore development alters cellular organization in rice anthers. The major cellular damage includes unusual starch accumulation in the plastids of the endothecium in postmeiotic anthers, abnormal vacuolation and hypertrophy of the tapetum, premature callose (1,3-beta-glucan) breakdown...

journal_title：Cell biology international

authors： Al Mamun E,Cantrill LC,Overall RL,Sutton BG

更新日期：2010-03-29 00:00:00

abstract：:Hypoxia-inducible factor-1α (HIF-1α) and hepatocyte growth factor (HGF) play important roles in postnatal neovascularization. However, the interaction of these two pathways is not fully understood. The present study utilized CoCl(2) treated-endothelial progenitor cells (EPCs) (EPCs exposure to CoCl(2) are under mimic ...

journal_title：Cell biology international

authors： Yu F,Lin Y,Zhan T,Chen L,Guo S

更新日期：2015-03-01 00:00:00

abstract：:Human tissues are sophisticated ensembles of various distinct cell types encapsulated in the biomechanical cues of the extracellular matrix. It has been known matrix stiffness plays a pivot role in cellular events and tissue-scale biological processes. Thus, materials that can mimic mechanical environments of tissues ...

journal_title：Cell biology international

authors： Zhao H,Xu K,Zhu P,Wang C,Chi Q

更新日期：2019-02-01 00:00:00

abstract：:Emergence of resistance to chemotherapy and radiotherapy is a major obstacle for the successful treatment of MM (multiple myeloma). Prednisone, vincristine and melphalan are commonly used chemotherapeutic agents for the treatment of MM. In the current study, we examined the presence of possible cross-resistance betwee...

journal_title：Cell biology international

authors： Mutlu P,Baran Y,Ural AU,Avcu F,Dirican B,Beyzadeoglu M,Gündüz U

更新日期：2011-07-01 00:00:00

abstract：:TZDs (thiazolidinediones) are prescribed as anti-Type II diabetes drugs, but little is known regarding whether TZDs regulate the expression of sPLA2 (secretory phospholipase A2) in macrophages. We have investigated the effects of pioglitazone on LPS (lipopolysaccharide)-induced production of TNF-alpha (tumour necrosis...

journal_title：Cell biology international

authors： Ao C,Huo Y,Qi L,Xiong Z,Xue L,Qi Y

更新日期：2010-07-01 00:00:00

abstract：:Peritoneal dialysis (PD) is often used to treat patients with end stage renal disease, and its long-term complications include excessive inflammation and oxidative stress. Allograft inflammatory factor 1 (AIF-1), as a cytoplasmic protein, is originally identified from infiltrating macrophages, and it was associated wi...

journal_title：Cell biology international

authors： Zhou Y,Li X,Yuan X,Hao L

更新日期：2019-05-01 00:00:00

abstract：:This study provides evidence that, in the soluble fraction from buffer-washed pea thylakoids, one form of soluble carbonic anhydrase (CA) is associated with rubisco in a stromal protein complex. On native-PAGE gels, it is present as a protein band with MW approximately 160 kDa. On SDS-PAGE gels, it is resolved as a si...

journal_title：Cell biology international

authors： Lazova GN,Stemler AJ

更新日期：2008-06-01 00:00:00

abstract：:A significant decrease in tissue pH or acidosis is a common feature of numerous diseases, including RA (rheumatoid arthritis). Cartilage homoeostasis is profoundly affected by local acidosis in the joints. The diuretic, amiloride, is neuroprotective in models of cerebral ischaemia, a property attributable to the inhib...

journal_title：Cell biology international

authors： Rong C,Chen FH,Jiang S,Hu W,Wu FR,Chen TY,Yuan FL

更新日期：2012-07-01 00:00:00

abstract：:The single-minded 2 gene (Sim2) plays a crucial role in the mental retardation of Down Syndrome (DS). To explore how Sim2 influences spatial memory, a DNA plasmid-encoding mouse Sim2 (mSim2) wrapped with liposome was bilaterally injected into the hippocampus of rats. The effect of overexpressing mSim2 on spatial learn...

journal_title：Cell biology international

authors： Meng X,Peng B,Shi J,Zheng Y,Chen H,Zhang J,Li L,Zhang C

更新日期：2006-10-01 00:00:00

abstract：:Cell-matrix and cell-cell interactions are important physiological determinants of cell growth, survival and transformation. Cell adhesion to the extra cellular matrix (ECM) via integrins also crucially influences the organization of the cytoskeleton. It triggers a cascade of intracellular biochemical events, which re...

journal_title：Cell biology international

authors： Rajeswari J,Pande G

更新日期：2002-01-01 00:00:00