Reduction of extracellular superoxide dismutase activity by decapeptide derived from FGF-receptor.


:Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF-receptor derived peptide was active as a negative modulator of enzyme activity. These results strengthen the thesis that HAV motifs are not only involved in homophilic interactions and suggest that soluble FGF-receptor molecules might moderate the activity of extracellular SOD.


Cell Biol Int


Willems J,Noppe W,Slegers H




Has Abstract


1995-11-01 00:00:00














  • Development of porcine tetraploid somatic cell nuclear transfer embryos is influenced by oocyte nuclei.

    abstract::Cloning efficiency in mammalian systems remains low because reprogramming of donor cells is frequently incomplete. Nuclear factors in the oocyte are removed by enucleation, and this removal may adversely affect reprogramming efficiency. Here, we investigated the role of porcine oocyte nuclear factors during reprogramm...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Fu B,Liu D,Ma H,Guo ZH,Wang L,Li ZQ,Peng FG,Bai J

    更新日期:2016-02-01 00:00:00

  • Amoeba proteus displays a walking form of locomotion.

    abstract::This report deals with observations on the directional locomotion of amoeba before and after fixation and scanning electron microscopy. The study was aimed at visualization of the stepwise events of directional movements. After the analysis of the data it is proposed that the amoeba undergoes a sequence of movement ev...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Cameron I,Rinaldi RA,Kirby G,Davidson D

    更新日期:2007-08-01 00:00:00

  • Enrichment and characterization of mouse putative epidermal stem cells.

    abstract::Epidermis, a continuously renewing tissue, is maintained by stem cells that proliferate and replenish worn out or damaged cells in the tissue during life. Cultured epidermal stem cells have great potential in scientific research and clinical application. However, isolating a pure and viable population of epidermal ste...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Zhou JX,Jia LW,Yang YJ,Peng S,Cao YJ,Duan EK

    更新日期:2004-01-01 00:00:00

  • DNA methyltransferase inhibitor RG108 and histone deacetylase inhibitors cooperate to enhance NB4 cell differentiation and E-cadherin re-expression by chromatin remodelling.

    abstract::Epigenetic silencing of cancer-related genes by abnormal methylation and the reversal of this process by DNA methylation inhibitors represents a promising strategy in cancer therapy. As DNA methylation affects gene expression and chromatin structure, we investigated the effects of novel DNMT (DNA methyltransferase) in...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Savickiene J,Treigyte G,Jazdauskaite A,Borutinskaite VV,Navakauskiene R

    更新日期:2012-11-01 00:00:00

  • Fructose sensitizes Jurkat cells oxidative stress-induced apoptosis via caspase-dependent and caspase-independent mechanisms.

    abstract::Whether fructose (FRU), as the sole energy source, confers a metabolic advantage on cancer cells against noxious stimuli is unknown. The aim of this study was to evaluate the effects of low (11 mM), moderate (25 mM), and high (55 mM) FRU concentrations alone or in combination with rotenone (ROT) or doxorubicin (DOX) i...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Diaz-Aguirre V,Velez-Pardo C,Jimenez-Del-Rio M

    更新日期:2016-11-01 00:00:00

  • Expression of primary cilia in mammalian cells.

    abstract::Mammalian cells in vivo frequently express primary cilia. Although some fully differentiated cell types rarely, if ever, express them, most do, indicating that they are regular cell organelles. Their expression can also be explored in vitro, where conditions--physical and chemical, intrinsic and extrinsic--permit expe...

    journal_title:Cell biology international

    pub_type: 杂志文章,评审


    authors: Wheatley DN,Wang AM,Strugnell GE

    更新日期:1996-01-01 00:00:00

  • Examination of actin polymerization and viscosity induced by cations and ionic strength when cross-linked by alpha-actinin.

    abstract::Increasing potassium chloride concentration from 0 to 100 mM and magnesium chloride from 0 to 2 mM show a parallel rate increase in polymerizing actin, whereas increasing calcium chloride concentration from 0 to 0.2 mM decreases the rate of polymerizing actin. The presence of alpha-actinin has little influence on the ...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Goldmann WH

    更新日期:2002-01-01 00:00:00

  • Decreased intracellular proteolysis correlates with the maintenance of a specific isoenzyme of cytochrome P-450.

    abstract::The rates of intracellular protein degradation, of identically labelled populations of proteins, were compared in hepatocytes cultured at 37 degrees (on an adsorbed collagen layer) and in cells preserved on gelatin gels at 10 degrees C. The half-lives of the long-lived proteins were 35.4+/-8.6 h (N=4) and 692.9+/-216....

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Evans PJ

    更新日期:1999-01-01 00:00:00

  • Reduced expression of the BRCA1 gene and increased chromosomal instability in MCF-7 cell line.

    abstract::Using clonal cell cultures, a significant increase in chromosomal aberrations (aneuplolidy, dicentrics and chromatid breaks) were observed in MCF-7 cells compared with HeLa. BRCA1 expression was lower in MCF-7 cells than in HeLa cells. Since BRCA1 is known to play a role in the maintenance of chromosomal integrity, th...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Kachhap SK,Vetale SP,Dange P,Ghosh SN

    更新日期:2001-01-01 00:00:00

  • Mitochondria, endoplasmic reticulum and actin filament behavior after PDT with chloroaluminum phthalocyanine liposomal in HeLa cells.

    abstract::Photodynamic therapy (PDT) for cancer is a therapeutic modality in the treatment of tumors in which visible light is used to activate a photosensitizer. Cell membranes have been identified as an important intracellular target for singlet oxygen produced during the photochemical pathway. This study analyzed the cytotox...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Maftoum-Costa M,Naves KT,Oliveira AL,Tedesco AC,da Silva NS,Pacheco-Soares C

    更新日期:2008-08-01 00:00:00

  • Smart mechanosensing machineries enable migration of vascular smooth muscle cells in atherosclerosis-relevant 3D matrices.

    abstract::At the early stage of atherosclerosis, neointima is formed due to the migration of vascular smooth muscle cells (VSMCs) from the media to the intima. VSMCs are surrounded by highly adhesive 3D matrices. They take specific strategies to cross various 3D matrices in the media, including heterogeneous collagen and mechan...

    journal_title:Cell biology international

    pub_type: 杂志文章,评审


    authors: Chi Q,Shan J,Ding X,Yin T,Wang Y,Jia D,Wang G

    更新日期:2017-06-01 00:00:00

  • Formation of membrane-bound inclusions and their associations with cytoplasmic channels in early prophase male meiocytes of Althaea rosea (L.) Cavan.

    abstract::To characterize the cytoplasmic structure reorganization during plant meiosis, the male meiocytes of Althaea rosea (L.) Cavan were examined under the combination of light and electron microscopy. Light microscopic observation of the toluidine blue-stained thick resin sections of young anthers revealed that the meiocyt...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Luo XJ,Liu XH,Wang CY,Wang XY

    更新日期:2008-04-01 00:00:00

  • The CLIC5 (chloride intracellular channel 5) involved in C2C12 myoblasts proliferation and differentiation.

    abstract::CLIC5 (chloride intracellular channel 5) is a CLIC (chloride intracellular channel) with various functions. Its high expression in skeletal muscle and association with actin-based cytoskeleton suggests that it may play an important role in muscle tissue. This study was conducted to examine whether CLIC5 regulates the ...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Li F,Yin J,Yue T,Liu L,Zhang H

    更新日期:2010-03-08 00:00:00

  • Adult peripheral blood mononuclear cells transdifferentiate in vitro and integrate into the retina in vivo.

    abstract::Adult peripheral blood-derived cells are able to differentiate into a variety of cell types, including nerve cells, liver-like cells and epithelial cells. However, their differentiation into retina-like cells is controversial. In the present study, transdifferentiation potential of human adult peripheral blood mononuc...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Liu Q,Guan L,Huang B,Li W,Su Q,Yu M,Xu X,Luo T,Lin S,Sun X,Chen M,Chen X

    更新日期:2011-06-01 00:00:00

  • Drosophila splicing factor SF2 knock-down mutant shows altered cell-cycle in vivo.

    abstract::Pioneering single gene study documents pre-mRNA processing proteins participation in the cell-cycle regulation of multi-cellular animals (Andersen and Tapon, 2008, J Biol Chem 283: 31256-67). Whole-genome RNAi screen in Drosophila tissue-culture cell lines demonstrates that 17 genes involved in RNA-processing are requ...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Dubatolova TD,Volkova EI,Omelyanchuk LV

    更新日期:2013-02-01 00:00:00

  • RNAi-mediated MMP-9 silencing inhibits mouse melanoma cell invasion and migration in vitro and in vivo.

    abstract::MMP-9 participates in tumour growth, invasion, metastasis and vascularisation. Thus, inhibition of MMP-9 may be involved in the process of tumourigenesis. We have investigated the effect of RNAi-mediated MMP-9 silencing on inhibiting invasion and migration of mouse melanoma cell B16. A specific and optimised siRNA vec...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Tang ZY,Liu Y,Liu LX,Ding XY,Zhang H,Fang LQ

    更新日期:2013-08-01 00:00:00

  • Pigment epithelium-derived factor delays cellular senescence of human mesenchymal stem cells in vitro by reducing oxidative stress.

    abstract::Mesenchymal stem cells (MSCs) are multipotent progenitor cells that represent a promising approach in the field of regenerative medicine; however, this potential diminishes with senescence. Pigment epithelium-derived factor (PEDF) gives some protection by reducing oxidative stress, which is known to accelerate cellula...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Cao Y,Yang T,Gu C,Yi D

    更新日期:2013-04-01 00:00:00

  • Angelica sinensis polysaccharide inhibits proliferation, migration, and invasion by downregulating microRNA-675 in human neuroblastoma cell line SH-SY5Y.

    abstract::Neuroblastoma is the most common tumor diagnosed in children and infants, with high recurrence and poor prognosis. Angelica sinensis polysaccharide (AP) whose average molecular weight is 72,900 Da possesses various bioactivities. We aimed to explore the effects of AP on neuroblastoma SH-SY5Y cells as well as the under...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Yang J,Shao X,Jiang J,Sun Y,Wang L,Sun L

    更新日期:2018-07-01 00:00:00

  • δ-Catenin interacts with LEF-1 and negatively regulates its transcriptional activity.

    abstract::δ-Catenin and β-catenin belong to different subfamilies of armadillo proteins but share some common binding partners, such as E-cadherin. This is the first study that demonstrated a novel common binding partner for δ-catenin and β-catenin, lymphoid enhancer factor-1 (LEF-1). We found that the N-terminus of δ-catenin (...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: He Y,Ki H,Kim H,Kim K

    更新日期:2015-08-01 00:00:00

  • ADAMTSL6β promotes fibrillin-1 microfibril assembly, which is possibly mediated via binding through the third thrombospondin type I domain to fibrillin-1.

    abstract::Fibrillin-1 is the major component of extracellular matrix microfibrils. Microfibrils dysfunction is responsible for the onset of various connective tissue diseases, including Marfan syndrome. Although ADAMTSL (a disintegrin and metalloproteinase with thrombospondin motifs-like) 6β is one of the fibrillin-1 binding pr...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Orimoto A,Fukuda T

    更新日期:2020-07-01 00:00:00

  • Heat shock protein 27 as a neuroprotective biomarker and a suitable target for stem cell therapy and pharmacotherapy in ischemic stroke.

    abstract::Ischemic stroke is a major common cause of death and long-term disability worldwide. Several pathophysiological events including excitotoxicity, oxidative/nitrative stress, inflammation, and apoptosis are involved in ischemic injuries. Recently, the molecular mechanisms involved in cerebral ischemia through a focus on...

    journal_title:Cell biology international

    pub_type: 杂志文章,评审


    authors: Behdarvandy M,Karimian M,Atlasi MA,Azami Tameh A

    更新日期:2020-02-01 00:00:00

  • Extracts from mdx and normal mouse skeletal muscle contain similar levels of mitogenic activity for myoblasts.

    abstract::The mdx mouse has been used as an animal model for human Duchenne muscular dystrophy (DMD). Unlike DMD, skeletal muscles of mdx mice undergo successful regeneration and do not show extensive fibrosis and functional impairment. Growth factors have been proposed to be involved in muscle growth and regeneration. We compa...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Chen G,Bressler BH,Quinn LS

    更新日期:1994-04-01 00:00:00

  • Tissues formed during distraction osteogenesis in the rabbit are determined by the distraction rate: localization of the cells that express the mRNAs and the distribution of types I and II collagens.

    abstract::An experimental model of leg lengthening was used to study the morphology of, the collagenous proteins present, and the collagen genes expressed in the regenerating tissue following 20% lengthening at four different distraction rates. At a distraction rate of 0.3 mm/day (8 weeks distraction), the regenerate consists o...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Li G,Virdi AS,Ashhurst DE,Simpson AH,Triffitt JT

    更新日期:2000-01-01 00:00:00

  • Kinesin-driven transport in cell-free environment.

    abstract::Conventional kinesin is an ATPase-active motor protein that is involved in the microtubule-dependent transport of cytoplasmic cargoes. The present paper provides a condensed overview on kinesin-1 and its motility generation outside a living cell. Moreover, it demonstrates that the neuron-specific kinesin KIF5A enables...

    journal_title:Cell biology international

    pub_type: 杂志文章,评审


    authors: Böhm KJ

    更新日期:2008-05-01 00:00:00

  • Gadolinium inhibits prostate cancer PC3 cell migration and suppresses osteoclast differentiation in vitro.

    abstract::This study examined whether Gd (gadolinium) could suppress prostate cancer cell migration and prostate cancer cell-induced osteoclast differentiation. MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide] and colony forming assay showed that GdCl3 treatment inhibited both cell viability and colony for...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Wang P,Zou XM,Huang J,Zhang TL,Wang K

    更新日期:2011-11-01 00:00:00

  • Upregulation of HO-1 is accompanied by activation of p38MAPK and mTOR in human oesophageal squamous carcinoma cells.

    abstract::Induction of HO-1 protein can have both beneficial and detrimental effects for cells, including regulating proliferation and apoptosis of several tumours. We have investigated the regulation of HO-1, p38MAPK and mTOR in the context of proliferation, cell cycle events and apoptosis of oesophageal squamous cell carcinom...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Hu JL,Xiao L,Li ZY,Wang Q,Chang Y,Jin Y

    更新日期:2013-06-01 00:00:00

  • In vitro culture and induced differentiation of sheep skeletal muscle satellite cells.

    abstract::Skeletal muscle satellite cells are adult muscle-derived stem cells receiving increasing attention. Sheep satellite cells have a greater similarity to human satellite cells with regard to metabolism, life span, proliferation and differentiation, than satellite cells of the rat and mouse. We have used 2-step enzymatic ...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Wu H,Ren Y,Li S,Wang W,Yuan J,Guo X,Liu D,Cang M

    更新日期:2012-06-01 00:00:00

  • Bcl-2 down-regulation by small interfering RNA induces Beclin1-dependent autophagy in human SGC-7901 cells.

    abstract::While Bcl-2 protein is involved in the regulation of apoptosis, recent research showed that Beclin1, described as the essential autophagy effector and haploinsufficient tumor suppressor, was originally isolated as a Bcl-2 interacting protein. Beclin1 interacts with Bcl-2 through a BH3 domain; nevertheless, the functio...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Du Y,Ji X

    更新日期:2014-10-01 00:00:00

  • Phallacidin stains the mitotic spindle of the diatom Pinnularia spp.

    abstract::Mitotic spindles of the diatom Pinnularia viritiformis stained with the fluorescent actin-labelling reagent bodipyphallacidin revealed actin among the chromosomes and extending along the spindle to the poles. This is the first report of actin's presence within spindles of this ecologically important group of organisms...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Sampson K

    更新日期:2004-01-01 00:00:00

  • Acridine orange accumulation in acid organelles of normal and vacuolated frog skeletal muscle fibres.

    abstract::The spatial distribution of acid membrane organelles and their relationships with normal and vacuolated transverse tubules has been studied in living frog skeletal muscle fibres using confocal microscopy. Acridine orange (AO) was used to evaluate acid compartments, while a lipophilic styryl dye, RH 414, was employed t...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Krolenko SA,Adamyan SY,Belyaeva TN,Mozhenok TP

    更新日期:2006-11-01 00:00:00