Reduction of extracellular superoxide dismutase activity by decapeptide derived from FGF-receptor.


:Several synthetic decapeptides containing an HAV tripeptide motif were tested for their ability to modulate the enzymatic activity of rat extracellular SOD, an enzyme which also contains an HAV motif. Out of nine decapeptides that were tested, only a FGF-receptor derived peptide was active as a negative modulator of enzyme activity. These results strengthen the thesis that HAV motifs are not only involved in homophilic interactions and suggest that soluble FGF-receptor molecules might moderate the activity of extracellular SOD.


Cell Biol Int


Willems J,Noppe W,Slegers H




Has Abstract


1995-11-01 00:00:00














  • Wnt-3 and Wnt-3a play different region-specific roles in neural crest development in avians.

    abstract::Wnt signalling regulates cell proliferation and cell fate determination during embryogenesis. However, little is known about the developmental role of one Wnt family member, Wnt-3, during avian development. To investigate the possible functions of Wnt-3, its expression pattern was determined using whole-mount in situ ...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Dongkyun K,Jinsoo S,Jin EJ

    更新日期:2010-07-01 00:00:00

  • Motogenic and biosynthetic response of adult skin fibroblasts to TGF-beta isoforms (-1, -2 and -3) determined by 'tissue response unit': role of cell density and substratum.

    abstract::We have recently demonstrated that the three principal mammalian isoforms of transforming growth factor beta (TGF-beta) exert distinct effects upon: (1) the migration of confluent adult fibroblasts into 3D gels of native type I collagen fibres (i.e. TGF-beta-1 and -2 had no apparent motogenic activity, whilst TGF-beta...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Ellis IR,Banyard J,Schor SL

    更新日期:1999-01-01 00:00:00

  • M2 macrophages induce EMT through the TGF-β/Smad2 signaling pathway.

    abstract::IPF is characterized by fibroblast accumulation, collagen deposition, and ECM remodeling, with myofibroblasts believed to be the effector cell type. Myofibroblasts develop due to EMT of lung alveolar epithelial cells, which can be induced by TGF-β. M2 macrophages, a macrophage subpopulation, secrete large amounts of T...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Zhu L,Fu X,Chen X,Han X,Dong P

    更新日期:2017-09-01 00:00:00

  • Human endometrial stem cells differentiation into functional hepatocyte-like cells.

    abstract::In spite of certain clinical limitations, such as teratoma formation, the use of stem cells is considered as an appropriate source in cell therapy and tissue engineering. This study shows human endometrial stem cells (hEnSCs) has exceptional differentiation ability in hepatocyte formation. hEnSCs have high purificatio...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Khademi F,Soleimani M,Verdi J,Tavangar SM,Sadroddiny E,Massumi M,Ai J

    更新日期:2014-07-01 00:00:00

  • Inhibition of Ca2+/calmodulin-dependent protein kinase or epidermal growth factor receptor tyrosine kinase abolishes lysophosphatidic acid-mediated DNA-synthesis in human myometrial smooth muscle cells.

    abstract::Human myometrial smooth muscle cells (SMCs) were used to evaluate the proliferative activity of lysophosphatidic acid (LPA). This study specifically focuses on the role of Ca(2+)/calmodulin-dependent protein (CaM) kinase and epidermal growth factor (EGF) receptor tyrosine kinase. Myometrial SMCs were cultured from bio...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Nilsson UK,Svensson SP

    更新日期:2003-01-01 00:00:00

  • Effect of silicon dioxide on expression of poly (ADP-ribose) polymerase mRNA and protein.

    abstract::Silicon dioxide induces acute injury and chronic pulmonary fibrosis. International Agency for Research on Cancer (IARC) listed it as a human carcinogen in 1996. However, the molecular mechanisms to induce cancer are not understood yet. The content of poly (ADP-ribose) polymerases (PARP) mRNA and protein in Hela cells ...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Gao A,Song S,Wang D,Peng W,Tian L

    更新日期:2009-07-01 00:00:00

  • Retinal and olfactory bulb precursor cells show distinct responses to FGF-2 and laminin.

    abstract::We analyzed whether the embryonic (E12.5-E14.5) mouse retina possesses genuine neural stem cells and how they respond to defined growth factors and extracellular matrix molecules. Whereas most combinations produced no or limited cell survival and proliferation in culture, FGF-2 plus heparin and laminin stimulated prol...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Otaegi G,de Pablo F,Vicario-Abejón C,de la Rosa EJ

    更新日期:2007-07-01 00:00:00

  • Electrically induced gel-to-gel phase-transition in neurons.

    abstract::At the end of transcardial perfusions with ice-cold physiological saline for 30 min or with isoosmotic potassium chloride for 5 min, but immediately before perfusion fixation, condenser-discharge electric shocks were administered to rats through surface electrodes pressed onto the temporal muscles of the scalped skull...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Kellermayer R,Zsombok A,Auer T,Gallyas F

    更新日期:2006-02-01 00:00:00

  • Polyamines and terminal deoxynucleotidyl transferase expression in KM 3 pre-B cell line during phorbol ester induced differentiation.

    abstract::The aliphatic polyamines, putrescine, spermine and spermidine belong to a category of molecules implicated in DNA replication. Their synthesis is strongly activated during the G1 period and they have been implicated in the regulation of cell proliferation and differentiation. Terminal transferase is a DNA polymerase p...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Stabellini G,Rapino M,Di Primio R,Trubiani O

    更新日期:1995-10-01 00:00:00

  • MicroRNA-195-5p suppresses osteosarcoma cell proliferation and invasion by suppressing naked cuticle homolog 1.

    abstract::MiR-195-5p has been shown to play an essential role in human cancer progression. Nevertheless, the biological role of miR-195-5p in osteosarcoma development remains unclear. In this study, real-time PCR was performed to examine the miR-195-5p expression in human osteosarcoma cell lines. CCK-8 assay and Transwell assay...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Qu Q,Chu X,Wang P

    更新日期:2017-03-01 00:00:00

  • Triptolide improves spinal cord injury by promoting autophagy and inhibiting apoptosis.

    abstract::We investigated the effect of triptolide (TP) on spinal cord injury (SCI), and its underlying mechanism. Following the establishment of the SCI model using YFP H-line transgenic mice, TP was intraperitoneally injected at a dose of 0.2 mg/kg once daily for 7 days. Behavioral tests, Nissl staining, and hematoxylin-eosin...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Zhu N,Ruan J,Yang X,Huang Y,Jiang Y,Wang Y,Cai D,Geng Y,Fang M

    更新日期:2020-03-01 00:00:00

  • Significance of eIF4E expression in skin squamous cell carcinoma.

    abstract::Cutaneous squamous cell carcinoma (SCC) is a malignant tumour of keratinising epidermal cells. This type of skin cancer is the second leading cause of death after melanoma, and it is the second most common type of non-melanoma skin cancer after basal cell carcinoma. The cellular and molecular events involved in the pr...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Salehi Z,Mashayekhi F,Shahosseini F

    更新日期:2007-11-01 00:00:00

  • Transcription factor XBP-1 is expressed during osteoblast differentiation and is transcriptionally regulated by parathyroid hormone (PTH).

    abstract::X-box-binding protein 1 (XBP-1) is a basic-region leucine zipper protein in the cyclic AMP response element binding protein/activating transcription factor (CREB/ATF) family of transcription factors involved in different cell-differentiation processes. We have investigated the expression of XBP-1 in differentiating MC...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Zambelli A,Mongiardini E,Villegas SN,Carri NG,Boot-Handford RP,Wallis GA

    更新日期:2005-08-01 00:00:00

  • Mechanism of low-temperature-induced pollen failure in rice.

    abstract::Low-temperature stress during microspore development alters cellular organization in rice anthers. The major cellular damage includes unusual starch accumulation in the plastids of the endothecium in postmeiotic anthers, abnormal vacuolation and hypertrophy of the tapetum, premature callose (1,3-beta-glucan) breakdown...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Al Mamun E,Cantrill LC,Overall RL,Sutton BG

    更新日期:2010-03-29 00:00:00

  • Examination of actin polymerization and viscosity induced by cations and ionic strength when cross-linked by alpha-actinin.

    abstract::Increasing potassium chloride concentration from 0 to 100 mM and magnesium chloride from 0 to 2 mM show a parallel rate increase in polymerizing actin, whereas increasing calcium chloride concentration from 0 to 0.2 mM decreases the rate of polymerizing actin. The presence of alpha-actinin has little influence on the ...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Goldmann WH

    更新日期:2002-01-01 00:00:00

  • CA(2+) mobilization in the human submandibular duct cell line A253.

    abstract::Ca(2+)mobilization induced by ATP, isoproterenol and the Ca(2+)-ATPase inhibitor thapsigargin in the human submandibular duct cell line A253 was investigated using the Ca(2+)-sensitive fluorescent indicator fura-2. ATP and isoproterenol increased cytosolic free Ca(2+)([Ca(2+)](i)) and subsequent exposure to thapsigarg...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Andersson C,Zhang AL,Roomans GM

    更新日期:2000-01-01 00:00:00

  • Gelatinases and metalloproteinase inhibitor secreted by murine colonic carcinoma cells with differing metastatic potential.

    abstract::Gelatinase activity and inhibitory activity against collagenase were measured in serum-free medium conditioned by murine colonic carcinoma cells with different spontaneous metastatic potentials to the lung. The medium conditioned with poorly metastatic NM11 cells gave higher inhibitory activity than that conditioned w...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Kishi J,Tanaka R,Koiwai O,Yamagata S,Numata Y,Hayakawa T,Shimizu S

    更新日期:1994-03-01 00:00:00

  • A fine structural study of the hippocampus and dorsal root ganglion in mouse trisomy 16, a model of Down's syndrome.

    abstract::Mouse trisomy 16 (Ts16) appears to provide an animal model of Down's syndrome in that a portion of mouse chromosome 16 is syntenic with part of human chromosome 21. Trisomy 21 in human beings leads to the mental retardation of Down's syndrome and in middle age, to some presenile anatomic and clinical features of Alzhe...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Lane NJ,Balbo A,Rapoport SI

    更新日期:1996-10-01 00:00:00

  • Metabolic profiling of normal hepatocyte and hepatocellular carcinoma cells via 1 H nuclear magnetic resonance spectroscopy.

    abstract::Hepatocellular carcinoma (HCC) causes death mainly by disseminated metastasis progression from the organ being confined. Different metastatic stages are closely related to cellular metabolic profiles. Normal hepatocyte and HepG2 cell line from low metastatic HCC were studied by NMR-based metabolomic techniques. Multiv...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Chen Y,Chen Z,Feng JH,Chen YB,Liao NS,Su Y,Zou CY

    更新日期:2018-04-01 00:00:00

  • Characterization and localization of dynein and myosins V and VI in the ovaries of queen bees.

    abstract::The presence of myosin and dynein in the ovaries of both Apis mellifera and Scaptotrigona postica was investigated in extracts and in histological sections. In the ovary extracts, motor proteins, myosins V, VI and dynein were detected by Western blot. In histological sections, they were detected by immunocytochemistry...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Patricio K,Calábria LK,Peixoto PM,Espindola FS,Da Cruz-Landim C

    更新日期:2010-10-01 00:00:00

  • Estrogen and progesterone receptors in carpal tunnel syndrome.

    abstract::Carpal tunnel syndrome (CTS) is a compression median nerve neuropathy common in women at menopausal age. The aim of this work was to study immunohistochemically the expression of estrogen (ER) and progesterone (PR) receptors in CTS and control specimens. Biopsies of transverse carpal ligament (TCL) and flexor tendon s...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Toesca A,Pagnotta A,Zumbo A,Sadun R

    更新日期:2008-01-01 00:00:00

  • Ion transport in primary cultures from human sweat gland coils studied with X-ray microanalysis.

    abstract::Chloride secretion in primary cultures of cells originating from the secretory coil of human sweat glands was investigated by electron probe X-ray microanalysis. The total intracellular Cl concentration was lowered by muscarinic agonists (carbachol and acetylcholine), as well as by the calcium ionophore A23187. The mu...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Mörk AC,Hongpaisan J,Roomans GM

    更新日期:1995-02-01 00:00:00

  • mGlu3 receptor blockade inhibits proliferation and promotes astrocytic phenotype in glioma stem cells.

    abstract::We have characterised, using both in vivo and in vitro methods, the effects of the metabotropic glutamate receptor subtype 3 (mGlu3) antagonist (LY341495) and agonist (LY379268) on the proliferation and differentiation of glioma stem cells (GSC). For in vitro studies, a CCK-8 assay was used to determine the cell proli...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Zhou K,Song Y,Zhou W,Zhang C,Shu H,Yang H,Wang B

    更新日期:2014-04-01 00:00:00

  • Haemoglobin biosynthesis site in rabbit embryo erythroid cells.

    abstract::Properly metabolized globin synthesis and iron uptake are indispensable for erythroid cell differentiation and maturation. Mitochondrial participation is crucial in the process of haeme synthesis for cytochromes and haemoglobin. We studied the final biosynthesis site of haemoglobin using an ultrastructural approach, w...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Cianciarullo AM,Bertho AL,Soares MJ,Hosoda TM,Nogueira-Silva S,Beçak W

    更新日期:2003-01-01 00:00:00

  • Behavior of stem cells under outer-space microgravity and ground-based microgravity simulation.

    abstract::With rapid development of space engineering, research on life sciences in space is being conducted extensively, especially cellular and molecular studies on space medicine. Stem cells, undifferentiated cells that can differentiate into specialized cells, are considered a key resource for regenerative medicine. Researc...

    journal_title:Cell biology international

    pub_type: 杂志文章,评审


    authors: Zhang C,Li L,Chen J,Wang J

    更新日期:2015-06-01 00:00:00

  • Association of nucleus and centrosome: magnet or velcro?

    abstract::A structural link between cell's nucleus and centrosome was proposed years ago. Such a link was suggested to maintain nucleus-centrosome axis, determine polarity of interphase cells and ensure spindle assembly in mitotic cells. The idea of structural link is supported by the facts that centrosomes are usually located ...

    journal_title:Cell biology international

    pub_type: 杂志文章,评审


    authors: Burakov AV,Nadezhdina ES

    更新日期:2013-02-01 00:00:00

  • Vertebrate primary cilia: a sensory part of centrosomal complex in tissue cells, but a "sleeping beauty" in cultured cells?

    abstract::Primary cilium development along with other components of the centrosome in mammalian cells was analysed ultrastructurally and by immunofluorescent staining with anti-acetylated tubulin antibodies. We categorized two types of primary cilia, nascent cilia that are about 1microm long located inside the cytoplasm, and tr...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Alieva IB,Vorobjev IA

    更新日期:2004-01-01 00:00:00

  • Role of p53 in preadipocyte differentiation.

    abstract::Insulin resistance, diabetes and many kinds of cancers are common in overweight and obese individuals. The tumor suppressor p53 is important in securing genetic stability, but its role in the regulation of metabolic processes and cell differentiation remains unclear. We have investigated the role of p53 in adipocyte d...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Huang Q,Liu M,Du X,Zhang R,Xue Y,Zhang Y,Zhu W,Li D,Zhao A,Liu Y

    更新日期:2014-12-01 00:00:00

  • Culture of osteogenic cells from human alveolar bone: a useful source of alkaline phosphatase.

    abstract::The aim of this study was to obtain membrane-bound alkaline phosphatase from osteoblastic-like cells of human alveolar bone. Cells were obtained by enzymatic digestion and maintained in primary culture in osteogenic medium until subconfluence. First passage cells were cultured in the same medium and at 7, 14, and 21 d...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Simão AM,Beloti MM,Rosa AL,de Oliveira PT,Granjeiro JM,Pizauro JM,Ciancaglini P

    更新日期:2007-11-01 00:00:00

  • High resolution scanning force microscopy of cardiac myocytes.

    abstract::The advent of scanning probe microscopy has introduced a powerful new method of probing the structural features of biological specimens. In this study, high resolution atomic force microscopy micrographs of single, isolated, cardiac myocytes are presented. Significantly, our images show not only the features to be exp...

    journal_title:Cell biology international

    pub_type: 杂志文章


    authors: Davis JJ,Hill HA,Powell T

    更新日期:2001-01-01 00:00:00