Drosophila splicing factor SF2 knock-down mutant shows altered cell-cycle in vivo.

abstract：:It has been reported that chronic inflammation of the vessel wall is a hallmark of atherosclerosis. Interleukin-6 (IL-6) is regarded as an important modulator of inflammatory events occurring during all stages of atherogenesis. Although many factors that induce IL-6 expression have been identified, the effect of homoc...

journal_title：Cell biology international

authors： Zhang L,Jin M,Hu XS,Zhu JH

更新日期：2006-07-01 00:00:00

abstract：:Tripartite motif protein 25 (TRIM25) expression was altered in various human cancers. Herein, we found that the expression of TRIM25 was elevated in hepatocellular carcinoma (HCC) tissues and cell lines. Knockdown of TRIM25 increased the sensitivity of HCC HepG2 cells to epirubicin (EPI), as indicated by reduced cell ...

journal_title：Cell biology international

authors： Yuan P,Zheng A,Tang Q

更新日期：2020-07-01 00:00:00

abstract：:Emerging evidence suggests that miR-143 plays an important role in the regulation of tumor sensitivity to chemotherapeutic agents. The study explores the underlying mechanism of miR-143 in reversing cisplatin resistance in ovarian cancer. The cisplatin-resistant ovarian cancer cell line A2780/CDDP was induced and esta...

journal_title：Cell biology international

authors： Han X,Liu D,Zhou Y,Wang L,Hou H,Chen H,Zhang L,Chen W,Li X,Zhao L

更新日期：2021-01-01 00:00:00

abstract：:Cytoplasmic proteins with binding capability to AU-rich instability determinant sequences (ARE) of tumour necrosis factor alpha (TNFalpha) mRNA 3' untranslated region (3'UTR) were assessed in human lymphoid cells. In vitro label transfer experiments using wild type as well as mutant sequences in which the 70 nucleotid...

journal_title：Cell biology international

authors： Henics T

更新日期：1999-01-01 00:00:00

abstract：:The diabetic milieu is believed to change the activity, or result in damage of podocytes-a key component of the glomerular filtration barrier and known to secrete matrix for glomerular basement membrane. This in turn contributes to diabetic nephropathy. However, how podocyte dysfunction is triggered in diabetic nephro...

journal_title：Cell biology international

authors： Liu Y,Long L,Yuan F,Liu F,Liu H,Peng Y,Sun L,Chen G

更新日期：2015-02-01 00:00:00

abstract：:Neuroinflammatory disorders such as Alzheimer's and Parkinson's diseases are characterised by chronic inflammation and loss of vascular integrity. Bradykinin 1 receptor (B1R) activation has been implicated in many neuroinflammatory diseases, but the contribution of B1R to inflammation and vascular breakdown is yet to ...

journal_title：Cell biology international

authors： Mugisho OO,Robilliard LD,Nicholson LFB,Graham ES,O'Carroll SJ

更新日期：2019-09-09 00:00:00

abstract：:The dynamic state of post-translational acetylation of eukaryotic histones is maintained by histone acetyltransferases (HATs) and histone deacetylases (HDACs). HATs and HDACs have been shown to be components of various regulatory protein complexes in the cell. Their enzymatic activities, intracellular localization and...

journal_title：Cell biology international

authors： Brandtner EM,Lechner T,Loidl P,Lusser A

更新日期：2002-01-01 00:00:00

abstract：:The objective of this study was to examine the changes in the activity and expression of ectonucleotidase enzymes in the model of unilateral cortical stab injury (CSI) in rat. The activities of ecto-nucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) and ecto 5'-nucleotidase were assessed by measuring the levels ...

journal_title：Cell biology international

authors： Nedeljkovic N,Bjelobaba I,Subasic S,Lavrnja I,Pekovic S,Stojkov D,Vjestica A,Rakic L,Stojiljkovic M

更新日期：2006-06-01 00:00:00

abstract：:Transplanted tumours could modify the intensity and temporal distribution of the cellular proliferation in normal cell populations, and partial hepatectomy alters the serum concentrations of substances involved in cellular proliferation, leading to the compensatory liver hyperplasia. The following experiments were des...

journal_title：Cell biology international

authors： García MN,Andrini LB,Inda AM,Ronderos JR,Hijano JC,Errecalde AL

更新日期：2010-02-05 00:00:00

abstract：:The focal adhesion protein vinculin has been implicated in associating with soluble and membranous phospholipids. Detailed investigations over the past ten years describe the intermolecular interactions of the vinculin tail domain with soluble and membrane phospholipids. Previous studies have implied that the tail's u...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2018-08-01 00:00:00

abstract：:Expression of four major reprogramming transgenes, including Oct4, Sox2, Klf4 and c-myc, in somatic cells enables them to have pluripotency. These cells are iPSC (induced pluripotent stem cell) that currently show the greatest potential for differentiation into cells of the three germ lineages. One of the issues facin...

journal_title：Cell biology international

authors： Shoae-Hassani A,Sharif S,Verdi J

更新日期：2011-10-01 00:00:00

abstract：:The cytokertatins in respiratory epithelial cells (REC) of human nasal polyps and turbinates were analyzed by immunohistochemistry. Cytokeratin 19 (CK19) was present in all REC, CK5 and 14 were expressed primarily in basal cells, and CK7, 8, and 18 were found in suprabasal cells. Differences in cytoplasmic locations w...

journal_title：Cell biology international

authors： Hicks W Jr,Ward R,Edelstein D,Hall L 3rd,Albino A,Hard R,Asch B

更新日期：1995-04-01 00:00:00

abstract：:The aim of this study was to examine the effects of glafenine hydrochloride (a nonsteroidal anti-inflammatory drug) on proliferation, clonogenic activity, cell-cycle, migration, and the extracellular matrix protein tenascin of human aortic smooth muscle cells (haSMCs) and human endothelial cells (ECs) in vitro.HaSMCs ...

journal_title：Cell biology international

authors： Schöber W,Tran QB,Muringaseril M,Wiskirchen J,Kehlbach R,Rodegerdts E,Wiesinger B,Claussen CD,Duda SH

更新日期：2003-01-01 00:00:00

abstract：:The exon 16-encoded juxtamembrane (JM) domain of human insulin receptor (hIR) harbors the NPEY motif which couples the insulin-activated hIR kinase to downstream signal transduction molecules. We sought to determine if signal transduction requires the entire exon 16-encoded 22-amino acid JM domain. Transfected CHO cel...

journal_title：Cell biology international

authors： Sattar AA,Berhanu C,Gebreselassie S,Berhanu P

更新日期：2007-08-01 00:00:00

abstract：:The Drosophila ovary provides an attractive model for studying the extrinsic or intrinsic factors that regulate the fate of germline stem cells (GSCs). Using this model, we identified a new role for Drosophila spaghetti (spag), encoding a homolog of human RNA polymerase II-associated protein 3 (RPAP3), in regulating t...

journal_title：Cell biology international

authors： Chen D,Tao X,Zhou L,Sun F,Sun M,Fang X

更新日期：2018-07-01 00:00:00

abstract：:Oxidative stress can be defined as the increase of oxidizing agents like reactive oxygen and nitrogen species, or the imbalance between the antioxidative defense mechanism and oxidants. Cell cycle checkpoint response can be defined as the arrest of the cell cycle functioning after damaging chemical exposure. This temp...

journal_title：Cell biology international

authors： Akcakaya H,Dal F,Tok S,Cinar SA,Nurten R

更新日期：2015-02-01 00:00:00

abstract：:Protein composition and functional activity of various polysome subpopulations isolated from Vicia faba L. leaves and Triticum aestivum L. and Hordeum vulgare L. seedlings were studied. Membrane- and cytoskeleton-bound polysomes were more active in the wheat germ cell-free translational system than free polysomes. Sev...

journal_title：Cell biology international

authors： Klyachko N,Aksenova L,Dunaeva M,Kulikova A

更新日期：2000-01-01 00:00:00

abstract：:Non-small-cell carcinoma (NSCLC) is the most common cancer along with high mortality rate worldwide. In the present study, our data showed that lncRNA MAF BZIP Transcription Factor G Antisense RNA 1 (MAFG-AS1) was over-expressed in NSCLC tissues and cell lines. Overexpression of MAFG-AS1 promoted the migration, invasi...

journal_title：Cell biology international

authors： Jia YC,Wang JY,Liu YY,Li B,Guo H,Zang AM

更新日期：2019-04-01 00:00:00

abstract：:Neuroinflammation is closely related with the pathogenesis and progress of neurodegenerative diseases including Alzheimer's disease (AD). Loganin, an iridoid glycoside obtained from traditional Chinese medicine Cornus officinalis, has properties of inhibiting inflammation and improving memory. The present study was ai...

journal_title：Cell biology international

authors： Cui Y,Wang Y,Zhao D,Feng X,Zhang L,Liu C

更新日期：2018-12-01 00:00:00

abstract：:Recently, we reported that human PDB (placental decidua basalis) is an excellent source of MSCs (mesenchymal stem cells), meanwhile, PDB-MSCs could survive under hypoxia and serum deprivation. Herein, we investigated the proliferation, clonogentic efficiency, phenotypes, metabolic activity and cytokines secretion of P...

journal_title：Cell biology international

authors： Huang YC,Yang ZM,Jiang NG,Chen XH,Li XQ,Tan MY,Zhou KP,Tang L,Xie HQ,Deng L

更新日期：2010-01-27 00:00:00

abstract：:This study examined whether Gd (gadolinium) could suppress prostate cancer cell migration and prostate cancer cell-induced osteoclast differentiation. MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide] and colony forming assay showed that GdCl3 treatment inhibited both cell viability and colony for...

journal_title：Cell biology international

authors： Wang P,Zou XM,Huang J,Zhang TL,Wang K

更新日期：2011-11-01 00:00:00

abstract：:Cloning efficiency in mammalian systems remains low because reprogramming of donor cells is frequently incomplete. Nuclear factors in the oocyte are removed by enucleation, and this removal may adversely affect reprogramming efficiency. Here, we investigated the role of porcine oocyte nuclear factors during reprogramm...

journal_title：Cell biology international

authors： Fu B,Liu D,Ma H,Guo ZH,Wang L,Li ZQ,Peng FG,Bai J

更新日期：2016-02-01 00:00:00

abstract：:Introns of plant tubulin genes are useful molecular tools to study IME (Intron Mediated Enhancement of gene expression) and to define plant genetic and evolutionary relationships through ILP (Intron Length Polymorphism). Here we show that the intron present within the 5'UTR sequence of some rice beta-tubulin genes can...

journal_title：Cell biology international

authors： Breviario D,Gianì S,Ponzoni E,Mastromauro F,Morello L

更新日期：2008-05-01 00:00:00

abstract：:Cell proliferation rates of diagnostic marrow aspirate cells of 21 children with Acute Lymphoblastic Leukaemia and 16 controls were compared using immunocytochemical labelling of PCNA and Ki-67 antigen as assessed by Confocal Laser Scanning Microscopy. The results showed an unexpected, highly significant degree of dis...

journal_title：Cell biology international

authors： Ball LM,Pope J,Howard CV,Eccles P,van Velzen D

更新日期：1994-09-01 00:00:00

abstract：:Cell behaviour in 3D environments can be significantly different from those in 2D cultures. With many different 3D matrices being developed and many experimental modalities used to modulate cell behaviour in 3D, it is necessary to develop high throughput techniques to study behaviour in 3D. We report on a 3D array on ...

journal_title：Cell biology international

authors： Zhao S,Gao R,Devreotes PN,Mogilner A,Zhao M

更新日期：2013-09-01 00:00:00

abstract：:Gelatinase activity and inhibitory activity against collagenase were measured in serum-free medium conditioned by murine colonic carcinoma cells with different spontaneous metastatic potentials to the lung. The medium conditioned with poorly metastatic NM11 cells gave higher inhibitory activity than that conditioned w...

journal_title：Cell biology international

authors： Kishi J,Tanaka R,Koiwai O,Yamagata S,Numata Y,Hayakawa T,Shimizu S

更新日期：1994-03-01 00:00:00

abstract：:Treatment of cultured rat osteoblasts with staurosporine caused a rapid outgrowth of long slender cellular processes and the formation of stellate cells. The number of stellate cells increased with higher concentrations of and longer incubation with staurosporine. Scanning electron microscopy (SEM) revealed that the s...

journal_title：Cell biology international

authors： Yang RS,Lu KS,Fu WM,Liu TK,Lin-Shiau SY

更新日期：1993-01-01 00:00:00

abstract：:MiR-195-5p has been shown to play an essential role in human cancer progression. Nevertheless, the biological role of miR-195-5p in osteosarcoma development remains unclear. In this study, real-time PCR was performed to examine the miR-195-5p expression in human osteosarcoma cell lines. CCK-8 assay and Transwell assay...

journal_title：Cell biology international

authors： Qu Q,Chu X,Wang P

更新日期：2017-03-01 00:00:00

abstract：:The rates of intracellular protein degradation, of identically labelled populations of proteins, were compared in hepatocytes cultured at 37 degrees (on an adsorbed collagen layer) and in cells preserved on gelatin gels at 10 degrees C. The half-lives of the long-lived proteins were 35.4+/-8.6 h (N=4) and 692.9+/-216....

journal_title：Cell biology international

authors： Evans PJ

更新日期：1999-01-01 00:00:00

abstract：:Resistance to radiotherapy and chemotherapy has been a major problem of conventional cancer therapies, which consequently leads to cancer relapse and cancer-related death. It is known that cancer stem cells (CSCs) play a key role in therapy resistance and CSC-based targeted therapies have been considered as a powerful...

journal_title：Cell biology international

authors： Johari B,Rahmati M,Nasehi L,Mortazavi Y,Faghfoori MH,Rezaeejam H

更新日期：2020-12-01 00:00:00