Oxidized low-density lipoprotein induces hematopoietic stem cell senescence.

abstract：:The mdx mouse has been used as an animal model for human Duchenne muscular dystrophy (DMD). Unlike DMD, skeletal muscles of mdx mice undergo successful regeneration and do not show extensive fibrosis and functional impairment. Growth factors have been proposed to be involved in muscle growth and regeneration. We compa...

journal_title：Cell biology international

authors： Chen G,Bressler BH,Quinn LS

更新日期：1994-04-01 00:00:00

abstract：:Fndc5 has been recently recognized as a myokine which could be cleaved and secreted into blood stream. It is termed as irisin with an important role in thermogenesis and energy homeostasis. Increased expression of Fndc5 has been reported upon retinoic acid treatment during neural differentiation and its knockdown decr...

journal_title：Cell biology international

authors： Forouzanfar M,Rabiee F,Ghaedi K,Beheshti S,Tanhaei S,Shoaraye Nejati A,Jodeiri Farshbaf M,Baharvand H,Nasr-Esfahani MH

更新日期：2015-05-01 00:00:00

abstract：:Ras/myc-transformed serum-free mouse embryo (ras/myc SFME) cells were treated with interferon-gamma (IFN-gamma; 100 U/ml) and/or lipopolysaccharide (LPS; 0.5 microg/ml) for 24 h to simulate inflammatory and infectious conditions and investigate their effects on the expression of inducible nitric oxide synthase (iNOS) ...

journal_title：Cell biology international

authors： Yamaguchi H,Kidachi Y,Umetsu H,Ryoyama K

更新日期：2008-08-01 00:00:00

abstract：:Mitotic spindles of the diatom Pinnularia viritiformis stained with the fluorescent actin-labelling reagent bodipyphallacidin revealed actin among the chromosomes and extending along the spindle to the poles. This is the first report of actin's presence within spindles of this ecologically important group of organisms...

journal_title：Cell biology international

authors： Sampson K

更新日期：2004-01-01 00:00:00

abstract：:This review summarizes original and literature data on changes in the ultrastructure of major cell organelles during apoptosis obtained by transmission electron microscopy. Organelles that make the most crucial contribution to the initiation of apoptosis: plasma membrane, mitochondria, proteasomes, Golgi apparatus, an...

journal_title：Cell biology international

authors： Snigirevskaya ES,Komissarchik YY

更新日期：2019-07-01 00:00:00

abstract：:Most hepatomas have a defect in prothrombin carboxylation, and can secrete under-carboxylated prothrombin or des-gamma-carboxy-prothrombin (DCP), the function of which is unknown. We considered that the prothrombin-DCP axis might also be involved in growth control. Hepatocytes and hepatoma cells were treated with prot...

journal_title：Cell biology international

authors： Carr BI,Kar S,Wang M,Wang Z

更新日期：2007-09-01 00:00:00

abstract：:Metallothionein (MT), a cysteine-rich, metal-binding protein, is involved in homeostatic regulation of essential metals and protection of cells against oxidative injury. It has been shown that oxidative stress is associated with pathogenesis of osteoporosis and is capable of inhibiting osteoblastic differentiation of ...

journal_title：Cell biology international

authors： Liu AL,Zhang ZM,Zhu BF,Liao ZH,Liu Z

更新日期：2004-01-01 00:00:00

abstract：:Type I diabetes is characterized by the deficiency of endocrine beta cells in the pancreatic islets of Langerhans and transplantation of islet cells can be an effective therapeutic approach. Embryonic stem cells can be differentiated into any cell type, and therefore represent an unlimited source of islet cells for th...

journal_title：Cell biology international

authors： Chen C,Zhang Y,Sheng X,Huang C,Zang YQ

更新日期：2008-04-01 00:00:00

abstract：:Fgf8 is a member of the fibroblast growth factor (FGF) family that plays an important role in early neural development. Cellular aggregation and retinoic acid (RA) are needed for mouse embryonic carcinoma (EC) P19 cell neural differentiation. We have examined the Fgf8 gene in P19 cells during neural differentiation an...

journal_title：Cell biology international

authors： Alam AH,Suzuki H,Tsukahara T

更新日期：2009-09-01 00:00:00

abstract：:Calcium loss and muscle atrophy are two of the main metabolic changes experienced by astronauts and crew members during exposure to microgravity in space. Calcium and cytoskeletal events were investigated within sea urchin embryos which were cultured in space under both microgravity and 1 g conditions. Embryos were fi...

journal_title：Cell biology international

authors： Schatten H,Chakrabarti A,Taylor M,Sommer L,Levine H,Anderson K,Runco M,Kemp R

更新日期：1999-01-01 00:00:00

abstract：:In spite of certain clinical limitations, such as teratoma formation, the use of stem cells is considered as an appropriate source in cell therapy and tissue engineering. This study shows human endometrial stem cells (hEnSCs) has exceptional differentiation ability in hepatocyte formation. hEnSCs have high purificatio...

journal_title：Cell biology international

authors： Khademi F,Soleimani M,Verdi J,Tavangar SM,Sadroddiny E,Massumi M,Ai J

更新日期：2014-07-01 00:00:00

abstract：:Arginine vasopressin (AVP)-induced tyrosine phosphorylation was studied in a rat smooth muscle cell line, A-10, by western blotting, using a monoclonal antibody against phosphotyrosine. AVP stimulated the phosphorylation of several cellular proteins of molecular mass 60-130 kDa in a time- and dose-dependent manner. Ph...

journal_title：Cell biology international

authors： Gonzalez CB,Reyes CE,Figueroa CD,Barra V,Troncoso S

更新日期：1999-01-01 00:00:00

abstract：:Rab11, a small GTP binding protein involved in vesicular trafficking, has emerged as a key player in regulating various cellular events during Drosophila development and differentiation. In our earlier study a P-insertion line, Rab11mo, was established as a new hypomorphic allele of Rab11 gene, showing degenerated eye...

journal_title：Cell biology international

authors： Tiwari AK,Alone DP,Roy JK

更新日期：2008-09-01 00:00:00

abstract：:Hypoxia-inducible factor-1α (HIF-1α) and hepatocyte growth factor (HGF) play important roles in postnatal neovascularization. However, the interaction of these two pathways is not fully understood. The present study utilized CoCl(2) treated-endothelial progenitor cells (EPCs) (EPCs exposure to CoCl(2) are under mimic ...

journal_title：Cell biology international

authors： Yu F,Lin Y,Zhan T,Chen L,Guo S

更新日期：2015-03-01 00:00:00

abstract：:At the end of transcardial perfusions with ice-cold physiological saline for 30 min or with isoosmotic potassium chloride for 5 min, but immediately before perfusion fixation, condenser-discharge electric shocks were administered to rats through surface electrodes pressed onto the temporal muscles of the scalped skull...

journal_title：Cell biology international

authors： Kellermayer R,Zsombok A,Auer T,Gallyas F

更新日期：2006-02-01 00:00:00

abstract：:Almost universally, the effective stimulus for mammalian 9+0 primary cilia has been taken to be bending. In this article I point out that in several physiological contexts there is great advantage in detecting pressure differences across the cell wall, i.e. axially directed forces pushing fluid to and fro through the ...

journal_title：Cell biology international

authors： Bell A

更新日期：2008-04-01 00:00:00

abstract：:The efficacies of chemotherapeutic agents are often limited by side effects and acquired drug resistance. We have investigated whether the differential expression pattern of 14-3-3σ affects cisplatin response in non-small cell lung cancer cell lines. Two pairs of parental/cisplatin resistant cell lines (A549/CRA549 an...

journal_title：Cell biology international

authors： Cetintas VB,Tetik A,Cok G,Kucukaslan AS,Kosova B,Gunduz C,Veral A,Eroglu Z

更新日期：2013-01-01 00:00:00

abstract：:Stem/progenitor cells hold promise for alleviating/curing type 1 diabetes due to the capacity to differentiate into functional insulin-producing cells. The current study aims to assess the differentiation potential of human pancreatic IPCs (islet-derived progenitor cells). IPCs were derived from four human donors and ...

journal_title：Cell biology international

authors： Zhang Y,Ren Z,Zou C,Wang S,Luo B,Li F,Liu S,Zhang YA

更新日期：2011-05-01 00:00:00

abstract：:Properly metabolized globin synthesis and iron uptake are indispensable for erythroid cell differentiation and maturation. Mitochondrial participation is crucial in the process of haeme synthesis for cytochromes and haemoglobin. We studied the final biosynthesis site of haemoglobin using an ultrastructural approach, w...

journal_title：Cell biology international

authors： Cianciarullo AM,Bertho AL,Soares MJ,Hosoda TM,Nogueira-Silva S,Beçak W

更新日期：2003-01-01 00:00:00

abstract：:Stem cell biology has gained remarkable interest in recent years, driven by the hope of finding cures for numerous diseases including skin wound healing through transplantation medicine. Initially upon transplantation, these cells home to and differentiate within the injured tissue into specialised cells. Contrariwise...

journal_title：Cell biology international

authors： Jayaraman P,Nathan P,Vasanthan P,Musa S,Govindasamy V

更新日期：2013-10-01 00:00:00

abstract：:Non-small-cell carcinoma (NSCLC) is the most common cancer along with high mortality rate worldwide. In the present study, our data showed that lncRNA MAF BZIP Transcription Factor G Antisense RNA 1 (MAFG-AS1) was over-expressed in NSCLC tissues and cell lines. Overexpression of MAFG-AS1 promoted the migration, invasi...

journal_title：Cell biology international

authors： Jia YC,Wang JY,Liu YY,Li B,Guo H,Zang AM

更新日期：2019-04-01 00:00:00

abstract：:Conventional kinesin is an ATPase-active motor protein that is involved in the microtubule-dependent transport of cytoplasmic cargoes. The present paper provides a condensed overview on kinesin-1 and its motility generation outside a living cell. Moreover, it demonstrates that the neuron-specific kinesin KIF5A enables...

journal_title：Cell biology international

authors： Böhm KJ

更新日期：2008-05-01 00:00:00

abstract：:The focal adhesion protein vinculin has been implicated in associating with soluble and membranous phospholipids. Detailed investigations over the past ten years describe the intermolecular interactions of the vinculin tail domain with soluble and membrane phospholipids. Previous studies have implied that the tail's u...

journal_title：Cell biology international

authors： Goldmann WH

更新日期：2018-08-01 00:00:00

abstract：:Oxidative stress can be defined as the increase of oxidizing agents like reactive oxygen and nitrogen species, or the imbalance between the antioxidative defense mechanism and oxidants. Cell cycle checkpoint response can be defined as the arrest of the cell cycle functioning after damaging chemical exposure. This temp...

journal_title：Cell biology international

authors： Akcakaya H,Dal F,Tok S,Cinar SA,Nurten R

更新日期：2015-02-01 00:00:00

abstract：:The cytosolic lipid droplets (cLDs) store excess intracellular lipids, and perilipin-2 is believed to protect cLDs from degradation. Here, we investigated the role of the small G-protein Arf1 and the proteasome in the fates of perilipin-2 and cLDs. In oleate-loaded cells, upon brefeldin A (BFA) treatment, perilipin-2 ...

journal_title：Cell biology international

authors： Pauloin A,Adenot P,Hue-Beauvais C,Chanat E

更新日期：2016-02-01 00:00:00

abstract：:The first description of intrachromosomal fibers was made by Baranetzky in 1880. Since that time, a plethora of fibrillar substructures have been described inside the mitotic chromosomes, and published data indicate that chromosomes may be formed as a result of the hierarchical folding of chromatin fibers. In this rev...

journal_title：Cell biology international

authors： Kuznetsova MA,Sheval EV

更新日期：2016-11-01 00:00:00

abstract：:Zebularine is a cytidine analogue incorporated into DNA during replication, inhibiting DNA methyltransferase 1 (DNMT1), resulting in demethylation and changes in gene expression. Such modification may improve radiosensitivity in resistant lymphoma cells. The hypothesis of this study was that zebularine and radiation w...

journal_title：Cell biology international

authors： Bryan JN,Kumar SR,Jia F,Balkin ER,Lewis MR

更新日期：2014-02-01 00:00:00

abstract：:Forms of the protozoan of the Hepatozoon genus are detected free in the circulation and also within some of the erythrocytes of infected snakes. In healthy snakes, DNA fragmentation and cell death usually affect a few circulating erythrocytes in agreement with the long life span expected for these cells. In the presen...

journal_title：Cell biology international

authors： Miyamoto M,Mello ML

更新日期：2007-05-01 00:00:00

abstract：:The induction and maintenance of immunologic tolerance at the feto-maternal interface is necessary for a successful pregnancy. The most accepted hypothesis for the mechanism underlying this tolerance is that pregnancy-induced foetal antigen-specific maternal T regulatory (T(reg) ) cells mediate maternal tolerance to t...

journal_title：Cell biology international

authors： Hao K,Zhou Q,Chen W,Jia W,Zheng J,Kang J,Wang K,Duan T

更新日期：2013-02-01 00:00:00

abstract：:We previously reported that mechanical vibration-induced proinflammatory cytokines, interleukin-6 (IL-6) and IL-8, expression in human periodontal ligament (hPDL) cells, however, the underlying mechanism remained unclear. Mechanical stimuli are able to activate cellular responses by inducing the activation of several ...

journal_title：Cell biology international

authors： Phusuntornsakul P,Jitpukdeebodintra S,Pavasant P,Leethanakul C

更新日期：2020-02-01 00:00:00