Vacuolation in T-tubules as a model for tubular-vesicular transformations in biomembrane systems.

abstract：:A significant decrease in tissue pH or acidosis is a common feature of numerous diseases, including RA (rheumatoid arthritis). Cartilage homoeostasis is profoundly affected by local acidosis in the joints. The diuretic, amiloride, is neuroprotective in models of cerebral ischaemia, a property attributable to the inhib...

journal_title：Cell biology international

authors： Rong C,Chen FH,Jiang S,Hu W,Wu FR,Chen TY,Yuan FL

更新日期：2012-07-01 00:00:00

abstract：:Insulin resistance (IR) is a hallmark of type 2 diabetes mellitus (T2DM). This study aimed to explore the effects of rapamycin, a specific inhibitor of kinase mammalian target of rapamycin (mTOR), on IR in T2DM rats, and to validate whether the underlying mechanism was associated with autophagy. In this study, the mod...

journal_title：Cell biology international

authors： Zhou W,Ye S

更新日期：2018-09-01 00:00:00

abstract：:Expression of the canine 180-kDa ribosome receptor p180 in yeast induces the synthesis of RER, and increases the mRNAs of secretory pathway proteins, and protein secretion. To assess whether p180 is a master regulator of cell secretion in mammalian cells, we stably expressed red fluorescent forms of the human p180 var...

journal_title：Cell biology international

authors： Bai JZ,Leung E,Holloway H,Krissansen GW

更新日期：2008-05-01 00:00:00

abstract：:The cytokertatins in respiratory epithelial cells (REC) of human nasal polyps and turbinates were analyzed by immunohistochemistry. Cytokeratin 19 (CK19) was present in all REC, CK5 and 14 were expressed primarily in basal cells, and CK7, 8, and 18 were found in suprabasal cells. Differences in cytoplasmic locations w...

journal_title：Cell biology international

authors： Hicks W Jr,Ward R,Edelstein D,Hall L 3rd,Albino A,Hard R,Asch B

更新日期：1995-04-01 00:00:00

abstract：:We studied the genotoxic potential of a carcinogen in the human hepatoma cell line, HepG2, and in primary rat hepatocyte culture. HepG2 is a well differentiated human hepatoblastoma cell line with biotransforming capacity. Rat hepatocytes were obtained by the standard two-step in situ perfusion technique. Following be...

journal_title：Cell biology international

authors： Liu TY,Chao TW,Chiang SH,Chi CW

更新日期：1993-04-01 00:00:00

abstract：:The plasticity of human and murine bone marrow mesenchymal stem cells (BMSCs) has been proven by their ability to trans-differentiate to multilineage cells, including germ cells. We have investigated ability of goat BMSCs to trans-differentiate to germ cells with extrinsic (e.g., retinoic acid [RA] and BMP4 signalling...

journal_title：Cell biology international

authors： Yan G,Fan Y,Li P,Zhang Y,Wang F

更新日期：2015-01-01 00:00:00

abstract：:The influence of oxygen tension on the side population (SP) fraction sorted from ATDC5 chondroprogenitor cells was investigated. ATDC5 cells cultured in normoxia (20%) or hypoxia (1% oxygen) were compared. The SP fraction was significantly higher in the cells cultured in hypoxia. The gene expression of 3 ABC transport...

journal_title：Cell biology international

authors： Kishimoto KN,Oxford CL,Reddi AH

更新日期：2009-12-01 00:00:00

abstract：:Calcium loss and muscle atrophy are two of the main metabolic changes experienced by astronauts and crew members during exposure to microgravity in space. Calcium and cytoskeletal events were investigated within sea urchin embryos which were cultured in space under both microgravity and 1 g conditions. Embryos were fi...

journal_title：Cell biology international

authors： Schatten H,Chakrabarti A,Taylor M,Sommer L,Levine H,Anderson K,Runco M,Kemp R

更新日期：1999-01-01 00:00:00

abstract：:Hypoxia alters the biological functions of skeletal muscle cells to proliferate and differentiate into myotubes. However, the cellular responses of myoblasts to hypoxia differ according to the levels of oxygen and the types of cells studied. This study examined the effect of hypoxia (1% oxygen) on bovine satellite cel...

journal_title：Cell biology international

authors： Kook SH,Son YO,Lee KY,Lee HJ,Chung WT,Choi KC,Lee JC

更新日期：2008-08-01 00:00:00

abstract：:Pioneering single gene study documents pre-mRNA processing proteins participation in the cell-cycle regulation of multi-cellular animals (Andersen and Tapon, 2008, J Biol Chem 283: 31256-67). Whole-genome RNAi screen in Drosophila tissue-culture cell lines demonstrates that 17 genes involved in RNA-processing are requ...

journal_title：Cell biology international

authors： Dubatolova TD,Volkova EI,Omelyanchuk LV

更新日期：2013-02-01 00:00:00

abstract：:In spite of certain clinical limitations, such as teratoma formation, the use of stem cells is considered as an appropriate source in cell therapy and tissue engineering. This study shows human endometrial stem cells (hEnSCs) has exceptional differentiation ability in hepatocyte formation. hEnSCs have high purificatio...

journal_title：Cell biology international

authors： Khademi F,Soleimani M,Verdi J,Tavangar SM,Sadroddiny E,Massumi M,Ai J

更新日期：2014-07-01 00:00:00

abstract：:Prolapsus uteri in pelvic supportive disorders are common in elderly women, and their etiology remains unclear. We examined elastin-binding proteins (EBPs) and binding sites in cultured cardinal ligament fibroblasts derived from elderly patients with prolapsus uteri (HPLiF) and compared them with those from age-matche...

journal_title：Cell biology international

authors： Yamamoto M,Akazawa K,Aoyagi M,Yamamoto N,Yamamoto K

更新日期：2002-01-01 00:00:00

abstract：:The isolation and culture of articular chondrocytes is a prerequisite of their use in tissue engineering, but prolonged culture and passaging is associated with de-differentiation. In this paper we studied the influence of nanometric and micrometric grooves (85 nm to 8 microm in depth and 2 microm to 20 microm in widt...

journal_title：Cell biology international

authors： Hamilton DW,Riehle MO,Monaghan W,Curtis AS

更新日期：2005-06-01 00:00:00

abstract：:We review Don Gilbert's pioneering seminal contributions that both detailed the mathematical principles and the experimental demonstration of several of the key dynamic characteristics of life. Long before it became evident to the wider biochemical community, Gilbert proposed that cellular growth and replication neces...

journal_title：Cell biology international

authors： Gilbert K,Hammond KD,Brodsky VY,Lloyd D

更新日期：2020-06-01 00:00:00

abstract：:The synthesis of proteins from salt-tolerant Brassica oleracea L. var. botrytis L. subvar. cauliflora (Gars.) DC. (cauliflower) cell cultures is modified in relation to controls in several features. There are nine newly induced polypeptides in tolerant cultures (absent in control conditions). Some of them are only pre...

journal_title：Cell biology international

authors： Martín JP,Elavummoottil OC,Moreno ML

更新日期：1993-09-01 00:00:00

abstract：:Hypoxia-inducible factor-1α (HIF-1α) and hepatocyte growth factor (HGF) play important roles in postnatal neovascularization. However, the interaction of these two pathways is not fully understood. The present study utilized CoCl(2) treated-endothelial progenitor cells (EPCs) (EPCs exposure to CoCl(2) are under mimic ...

journal_title：Cell biology international

authors： Yu F,Lin Y,Zhan T,Chen L,Guo S

更新日期：2015-03-01 00:00:00

abstract：:Acylase 1 was investigated at the cellular level in the rat small intestine along the enterocyte-differentiation axis. As confirmed by microscopic analysis, villus tip cells and crypt cells of rat jejunal mucosa were successfully separated using the Weiser method. The proliferating undifferentiated crypt cells showed ...

journal_title：Cell biology international

authors： Cigna N,Nicoletti C,Durand A,Chaix JC,Giardina T,Perrier J

更新日期：2007-09-01 00:00:00

abstract：:In the past decades increasing lines of evidence have demonstrated that adipose tissue, as an endocrine organ plays a central role in metabolic homeostasis and its related maladies. CCAAT/enhancer-binding protein (C/EBP) family members and the nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) w...

journal_title：Cell biology international

authors： Zhao XY,Chen XY,Zhang ZJ,Kang Y,Liao WM,Yu WH,Xiang AP

更新日期：2015-04-01 00:00:00

abstract：:The unicellular Tetrahymena has receptors for hormones of higher vertebrates, produces these hormones, and their signal pathways are similar. The first encounter with a hormone in higher dose provokes the phenomenon of hormonal imprinting, by which the reaction of the cell is quantitatively modified. This modification...

journal_title：Cell biology international

authors： Kőhidai L,Lajkó E,Pállinger E,Csaba G

更新日期：2012-10-01 00:00:00

abstract：:Skeletal muscle satellite cells are adult muscle-derived stem cells receiving increasing attention. Sheep satellite cells have a greater similarity to human satellite cells with regard to metabolism, life span, proliferation and differentiation, than satellite cells of the rat and mouse. We have used 2-step enzymatic ...

journal_title：Cell biology international

authors： Wu H,Ren Y,Li S,Wang W,Yuan J,Guo X,Liu D,Cang M

更新日期：2012-06-01 00:00:00

abstract：:Transforming growth factor-β (TGF-β) is a potent inhibitor of the growth of normal mammary epithelial cells, and has a pleiotropic, context-dependent, concentration-dependent action. We found attenuation of TGF-β signalling in mammary adenoma carcinoma cells. Phosphorylation at the linker site of Smad2 occurred in a c...

journal_title：Cell biology international

authors： Sengupta S,Kundu S,Bhattacharyya A

更新日期：2013-05-01 00:00:00

abstract：:Treatment of cultured rat osteoblasts with staurosporine caused a rapid outgrowth of long slender cellular processes and the formation of stellate cells. The number of stellate cells increased with higher concentrations of and longer incubation with staurosporine. Scanning electron microscopy (SEM) revealed that the s...

journal_title：Cell biology international

authors： Yang RS,Lu KS,Fu WM,Liu TK,Lin-Shiau SY

更新日期：1993-01-01 00:00:00

abstract：:We analyzed the connection of changes in nucleus ploidy with changes in nucleolar apparatus of NIH 3T3 cells. The quantity of nucleoli does not depend on the quantity of nucleolar DNA, but instead depends on euploidy: the majority of euploid cells have 1-3 nucleoli. The quantity of DNA in the nucleolus is correlated w...

journal_title：Cell biology international

authors： Karalyan ZA,Djaghatspanyan NG,Gasparyan MH,Hakobyan LA,Abroyan LO,Magakyan YH,Ter-Pogossyan ZR,Kamalyan LA,Avagyan VY,Karalova EM

更新日期：2003-01-01 00:00:00

abstract：:Circulating endothelial progenitor cells (EPCs) play a key role in restoring endothelial function and enhancing angiogenesis. However, the effects of low-dose aspirin on circulating EPCs are not well known. We investigated the effects of low-dose aspirin on EPC migration, adhesion, senescence, proliferation, apoptosis...

journal_title：Cell biology international

authors： Hu Z,Zhang F,Yang Z,Zhang J,Zhang D,Yang N,Zhang Y,Cao K

更新日期：2008-07-01 00:00:00

abstract：:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme of the glycolytic pathway. Recent studies have demonstrated an additional role in apoptosis: GAPDH is targeted to the nucleus during apoptotic signalling. This nuclear transport has also been observed in serum-depleted cells, but it is reversible in fibr...

journal_title：Cell biology international

authors： Schmitz HD,Dutiné C,Bereiter-Hahn J

更新日期：2003-01-01 00:00:00

abstract：:Ricin is internalized after binding at the cell surface via lectin activity of the B-chain recognizing terminal galactose residues. Ricin-A chain is then translocated to the cytosol from various endocytic structures. Cell death is the result of catalytic inactivation of protein synthesis. Using (125)I-ricin overlays, ...

journal_title：Cell biology international

authors： Alami M,Taupiac MP,Beaumelle B

更新日期：1997-03-01 00:00:00

abstract：:Using flow cytometry and confocal microscopy, the presence of endorphin, serotonin and chorionic gonadotropin (hCG) was demonstrated in rat white blood cells and peritoneal mast cells. After a single neonatal treatment with beta-endorphin (hormonal imprinting), the mast cells of female rats reaching adulthood containe...

journal_title：Cell biology international

authors： Csaba G,Kovács P,Pállinger E

更新日期：2003-01-01 00:00:00

abstract：:Glycometabolism, particularly mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis, plays a central role in cell life activities. Glycometabolism can be reprogrammed to maintain the stemness or to induce the differentiation of stem cells, thereby regulating tissue repair and regeneration. However, research ...

journal_title：Cell biology international

authors： Wang L,Cheng L,Wang H,Pan H,Yang H,Shao M,Hu T

更新日期：2016-03-01 00:00:00

abstract：:Epilepsy was characterized by the occurrence of spontaneous recurrent epileptiform discharges (SREDs) in neurons. Previous studies suggested that microRNA (miR)-139-5p and the Notch pathway were implicated in Epilepsy; however, their interaction remained vague. Rat primary hippocampal neurons were isolated and identif...

journal_title：Cell biology international

authors： Zhao C,Yang F,Wei X,Zhang J

更新日期：2020-11-28 00:00:00

abstract：:The present study aimed to investigate the potassium currents and further explore the role of potassium channels in drug response of gastric cancer cells. By patch-clamp technique, potassium currents of human gastric cancer cell SGC7901 were recorded in the mode of voltage clamp. Both 4-aminopyridine (4-AP) and tetrae...

journal_title：Cell biology international

authors： Han Y,Shi Y,Han Z,Sun L,Fan D

更新日期：2007-07-01 00:00:00