Articular chondrocyte passage number: influence on adhesion, migration, cytoskeletal organisation and phenotype in response to nano- and micro-metric topography.

abstract：:Mesenchymal stem cells (MSCs) exists low efficiency to trans-differentiate into other germinal layer cell types. One key issue is to discover the effect of important factor on MSCs differentiation abiltiy. In this study, we investigated the role and mechanism of epiregulin (EREG) on the osteogenic differentiation and ...

journal_title：Cell biology international

authors： Cao Y,Shi R,Yang H,Zhang J,Ge L,Gao R,Fan Z

更新日期：2020-04-01 00:00:00

abstract：:The effects of cadmium Cd (II) ions on the physiology and biological activity of Trametes versicolor, a strain belonging to white-rotting Basidiomycetes, were examined. Cd (II) ions were added to 10-day-old cultures grown on a liquid medium, or at the time of inoculation. Our experiments showed that T. versicolor is a...

journal_title：Cell biology international

authors： Jarosz-Wilkolazka A,Malarczyk E,Pirszel J,Skowroński T,Leonowicz A

更新日期：2002-01-01 00:00:00

abstract：:Long non-coding (lncRNA) MALAT1 can be increased by hypoxia or ischemic limbs. Also, downregulation of MALAT1 contributes to reduction of cardiomyocyte apoptosis. However, the functional involvement of MALAT1 in myocardial ischemia-reperfusion (I/R) injury has not been defined. This study investigated the functional i...

journal_title：Cell biology international

authors： Zhao ZH,Hao W,Meng QT,Du XB,Lei SQ,Xia ZY

更新日期：2017-01-01 00:00:00

abstract：:In this study, we determined whether multilineage-differentiating stress-enduring (Muse) cells exist in rat bone marrow and elucidated their effects on protection against the injury of intestinal epithelial cells associated with inflammation. Rat Muse cells were separated from bone marrow mesenchymal stem cells (BMMSC...

journal_title：Cell biology international

authors： Sun D,Yang L,Cao H,Shen ZY,Song HL

更新日期：2020-02-01 00:00:00

abstract：:Dexmedetomidine (Dex) protects different cell types during hypoxia or ischemia-reperfusion injury by inhibiting cell apoptosis. However, the underlying mechanism and its impact on hepatic ischemia reperfusion injury are still not known. In this study, we established a model of oxygen-glucose deprivation/reperfusion (O...

journal_title：Cell biology international

authors： Zhou Z,Chen Q,Wan L,Zheng D,Li Z,Wu Z

更新日期：2018-09-01 00:00:00

abstract：:Neuroblastoma is one of the most common solid tumours in children (8-10% of all malignancies). Over 22% of cases have N-myc amplification associated with aggressively growing neuroblastomas. Oncogene-induced sensitization of cells to apoptosis is an important mechanism for suppression of tumorigenesis. Tumour suppress...

journal_title：Cell biology international

authors： Li T,Wang L,Ke XX,Gong XY,Wan JH,Hao XW,Xu M,Xiang Z,Cui ZB,Cui H

更新日期：2012-04-01 00:00:00

abstract：:Hyperglycemia is one of the most important pathogenesis of diabetic osteopathy. Several lines of studies indicate Runx2 plays a critical role in the process of osteogenic differentiation. However, little studies have analyzed the effect of Runx2 on osteoblast differentiation of rat bone mesenchymal stem cells (rBMSCs)...

journal_title：Cell biology international

authors： Chen Y,Hu Y,Yang L,Zhou J,Tang Y,Zheng L,Qin P

更新日期：2017-08-01 00:00:00

abstract：:An experimental model of leg lengthening was used to study the morphology of, the collagenous proteins present, and the collagen genes expressed in the regenerating tissue following 20% lengthening at four different distraction rates. At a distraction rate of 0.3 mm/day (8 weeks distraction), the regenerate consists o...

journal_title：Cell biology international

authors： Li G,Virdi AS,Ashhurst DE,Simpson AH,Triffitt JT

更新日期：2000-01-01 00:00:00

abstract：:A view is emerging that human amylin (HA) kills pancreatic islet beta-cells by apoptosis. This study strengthens this view by documenting time-dependent morphological and ultrastructural changes in 10 microm HA-treated cultured RINm5F islet beta-cells. Membrane blebbing and microvilli loss were the earliest detectable...

journal_title：Cell biology international

authors： Saafi EL,Konarkowska B,Zhang S,Kistler J,Cooper GJ

更新日期：2001-01-01 00:00:00

abstract：:Transplanted tumours could modify the intensity and temporal distribution of the cellular proliferation in normal cell populations, and partial hepatectomy alters the serum concentrations of substances involved in cellular proliferation, leading to the compensatory liver hyperplasia. The following experiments were des...

journal_title：Cell biology international

authors： García MN,Andrini LB,Inda AM,Ronderos JR,Hijano JC,Errecalde AL

更新日期：2010-02-05 00:00:00

abstract：:The plasticity of human and murine bone marrow mesenchymal stem cells (BMSCs) has been proven by their ability to trans-differentiate to multilineage cells, including germ cells. We have investigated ability of goat BMSCs to trans-differentiate to germ cells with extrinsic (e.g., retinoic acid [RA] and BMP4 signalling...

journal_title：Cell biology international

authors： Yan G,Fan Y,Li P,Zhang Y,Wang F

更新日期：2015-01-01 00:00:00

abstract：:Photodynamic therapy (PDT) for cancer is a therapeutic modality in the treatment of tumors in which visible light is used to activate a photosensitizer. Cell membranes have been identified as an important intracellular target for singlet oxygen produced during the photochemical pathway. This study analyzed the cytotox...

journal_title：Cell biology international

authors： Maftoum-Costa M,Naves KT,Oliveira AL,Tedesco AC,da Silva NS,Pacheco-Soares C

更新日期：2008-08-01 00:00:00

abstract：:Ca(2+)mobilization induced by ATP, isoproterenol and the Ca(2+)-ATPase inhibitor thapsigargin in the human submandibular duct cell line A253 was investigated using the Ca(2+)-sensitive fluorescent indicator fura-2. ATP and isoproterenol increased cytosolic free Ca(2+)([Ca(2+)](i)) and subsequent exposure to thapsigarg...

journal_title：Cell biology international

authors： Andersson C,Zhang AL,Roomans GM

更新日期：2000-01-01 00:00:00

abstract：:G protein-coupled estrogen receptor (GPER) is recently identified as a membrane-associated estrogen receptor that mediates non-genomic effects of estrogen. Our previous immunohistochemistry study found an association between GPER and the proliferation of epithelial ovarian cancer. However, the contributions and mechan...

journal_title：Cell biology international

authors： Liu H,Yan Y,Wen H,Jiang X,Cao X,Zhang G,Liu G

更新日期：2014-05-01 00:00:00

abstract：:Receptor-interacting serine/threonine kinase 4 (RIPK4) and transforming growth factor-β 1 (TGF-β1) play critical roles in the development and maintenance of the epidermis. A negative correlation between the expression patterns of RIPK4 and TGF-β signaling during epidermal homeostasis-related events and suppression of ...

journal_title：Cell biology international

authors： Dinçer T,Boz Er AB,Er İ,Toraman B,Yildiz G,Kalay E

更新日期：2020-03-01 00:00:00

abstract：:To better treat patients with non-small cell lung cancer (NSCLC), the investigations on novel molecules affecting NSCLC progression are of vital importance. Long noncoding RNAs (lncRNAs) are identified as pivotal regulators that can affect the cellular activities of carcinomas. Long intergenic non-protein coding RNA 6...

journal_title：Cell biology international

authors： Yang H,Yang W,Dai W,Ma Y,Zhang G

更新日期：2020-08-01 00:00:00

abstract：:Cardiac differentiation of human pluripotent stem cells may be induced under chemically defined conditions, wherein the regulation of Wnt/β-catenin pathway is often desirable. Here, we examined the effect of trolox, a vitamin E analog, on the cardiac differentiation of human embryonic stem cells (hESCs). 6-Hydroxy-2,5...

journal_title：Cell biology international

authors： Choe MS,Yeo HC,Bae CM,Han HJ,Baek KM,Kim JS,Lim KS,Shin IS,Chang W,Yun SP,Lee HJ,Lee MY

更新日期：2019-07-10 00:00:00

abstract：:To establish useful human normal cell lines, TERT (telomerase reverse transcriptase) cDNA was transfected into normal female lung fibroblast, TIG-1. After long-term-sub-cultivation of 74 individual clones selected for resistance to G418, we obtained 55 cultures with normal range of life span [75 PDL (population doubli...

journal_title：Cell biology international

authors： Kamada M,Kumazaki T,Matsuo T,Mitsui Y,Takahashi T

更新日期：2012-06-01 00:00:00

abstract：:The purpose of the study was to examine mechanisms controlling cell cycle progression/arrest and differentiation of mouse C2C12 myoblasts exposed to long-chain saturated fatty acid salt, palmitate. Treatment of proliferating myoblasts with palmitate (0.1 mmol/l) markedly decreased myoblast number. Cyclin A and cyclin ...

journal_title：Cell biology international

authors： Grabiec K,Milewska M,Błaszczyk M,Gajewska M,Grzelkowska-Kowalczyk K

更新日期：2015-09-01 00:00:00

abstract：:Cloning efficiency in mammalian systems remains low because reprogramming of donor cells is frequently incomplete. Nuclear factors in the oocyte are removed by enucleation, and this removal may adversely affect reprogramming efficiency. Here, we investigated the role of porcine oocyte nuclear factors during reprogramm...

journal_title：Cell biology international

authors： Fu B,Liu D,Ma H,Guo ZH,Wang L,Li ZQ,Peng FG,Bai J

更新日期：2016-02-01 00:00:00

abstract：:In the present study, we investigated the effects of tetramethylpyrazine (TMP) on hydrogen peroxide (H2O2)-induced apoptosis in PC12 cells. The apoptosis in H2O2-induced PC12 cells was accompanied by a decrease in Bcl-2/Bax protein ratio, release of cytochrome c to cytosol and the activation of caspase-3. TMP not only...

journal_title：Cell biology international

authors： Cheng XR,Zhang L,Hu JJ,Sun L,Du GH

更新日期：2007-05-01 00:00:00

abstract：:The influence of daunorubicin (DNR) on survival of human normal (S-126) and trisomic, with respect to chromosome 21 (T-164; S-240), skin fibroblasts and some parameters related to it, such as intracellular drug accumulation, distribution and interaction with cell membrane, were studied. The in vitro growth-inhibition ...

journal_title：Cell biology international

authors： Przybylska M,Koceva-Chyla A,Rózga B,Józwiak Z

更新日期：2001-01-01 00:00:00

abstract：:It has been demonstrated that the crude extract of mosquito larvae alters the mitotic rate of several mouse cell populations of young growing mice (25 +/- 1 days old). Furthermore, the dialysed fraction of the extract inhibited proliferation of hepatocytes from hepatectomized adult male mice (90 days old). Sampling du...

journal_title：Cell biology international

authors： Ronderos JR,Riccillo FL,Ottino A

更新日期：1996-08-01 00:00:00

abstract：:The biosynthesis of interleukin-6 receptor (IL-6R) and gp130 in vitro was blocked using specific antisense oligonucleotides (ASO) in HepG2 liver cells and the efficacy of various ASOs was tested on the generation of IL-6-induced junB mRNA. We used three ASOs specific for the IL-6 receptor, three specific for gp130 and...

journal_title：Cell biology international

authors： Varga VL,Fülöp AK,Holub MC,Tóth S,Szalai C,Falus A

更新日期：2001-01-01 00:00:00

abstract：:Introns of plant tubulin genes are useful molecular tools to study IME (Intron Mediated Enhancement of gene expression) and to define plant genetic and evolutionary relationships through ILP (Intron Length Polymorphism). Here we show that the intron present within the 5'UTR sequence of some rice beta-tubulin genes can...

journal_title：Cell biology international

authors： Breviario D,Gianì S,Ponzoni E,Mastromauro F,Morello L

更新日期：2008-05-01 00:00:00

abstract：:CLIC5 (chloride intracellular channel 5) is a CLIC (chloride intracellular channel) with various functions. Its high expression in skeletal muscle and association with actin-based cytoskeleton suggests that it may play an important role in muscle tissue. This study was conducted to examine whether CLIC5 regulates the ...

journal_title：Cell biology international

authors： Li F,Yin J,Yue T,Liu L,Zhang H

更新日期：2010-03-08 00:00:00

abstract：:The effect of an organochlorine pesticide benzene hexachloride (containing alpha, beta, gamma and delta isomers) on the phagocytic activity of the vegetative cells of Dictyostelium discoideum was investigated. Benzene hexachloride (BHC) at concentrations of 60 ppm and above inhibited the phagocytic activity as reveale...

journal_title：Cell biology international

authors： Gayatri R,Chatterjee S

更新日期：1993-03-01 00:00:00

abstract：:In the presence of low density lipoprotein (LDL), Chlamydia pneumoniae induces macrophage-derived foam cell formation, a typical pathological feature of early atherosclerosis. However, its mechanism has not been fully understood. Peroxisome proliferator-activated receptors (PPARs) are key regulators of macrophage lipi...

journal_title：Cell biology international

authors： Mei CL,He P,Cheng B,Liu W,Wang YF,Wan JJ

更新日期：2009-03-01 00:00:00

abstract：:To examine cytokine production in response to RSV infection, we assessed the levels of 29 cytokines released from RSV-infected human foetal lung fibroblasts. We also examined the relationships between the effects of fluticasone propionate and various signalling pathways in the cells. Twenty-four hours after infection ...

journal_title：Cell biology international

authors： Seki E,Yoshizumi M,Tanaka R,Ryo A,Ishioka T,Tsukagoshi H,Kozawa K,Okayama Y,Okabe-Kado J,Goya T,Kimura H

更新日期：2013-04-01 00:00:00

abstract：:Hematopoietic stem and progenitor cells (HSPCs) are attractive targets in regenerative medicine, although the differences in their homeostatic maintenance between sexes along time are still under debate. We accurately monitored hematopoietic stem cells (HSCs), common lymphoid progenitors (CLPs), and common myeloid pro...

journal_title：Cell biology international

authors： Gasco S,Rando A,Zaragoza P,García-Redondo A,Calvo AC,Osta R

更新日期：2017-12-01 00:00:00