Abstract:
:The structure difference between the free operator of the lac system d(GCTCACAAT).d(ATTGTGAGC) and the same operator complexed to the headpiece of the lac repressor has been investigated by 2-D-1H NMR spectroscopy in conjunction with molecular modelling in internal coordinates (JUMNA). The free and complexed operator adopt both a right-handed B helical conformation, but a more detailed analysis of the conformational parameters using the Curves program shows striking differences in the groove geometries, the rises, the twists and the total bending.
journal_name
Biochimiejournal_title
Biochimieauthors
Gincel E,Lancelot G,Maurizot JC,Thuong NT,Vovelle Fdoi
10.1016/0300-9084(94)90006-xsubject
Has Abstractpub_date
1994-01-01 00:00:00pages
141-51issue
2eissn
0300-9084issn
1638-6183pii
0300-9084(94)90006-Xjournal_volume
76pub_type
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