New nomenclature of the non-rod-shaped lactic acid bacteria.

abstract：:The major pterin in Tetrahymena pyriformis, strain W, earlier suggested to be L-threo-biopterin and named ciliapterin [1] is now identified as D-threo-neopterin (D-monapterin). This is the first example of a natural D-monapterin. This compound was characterized by its chromatographic behavior, its fluorescence propert...

journal_title：Biochimie

authors： Klein R,Tatischeff I,Tham G,Grolière CA

更新日期：1991-10-01 00:00:00

abstract：:We describe a method to compare two fluorescence anisotropy decay curves. After numerical deconvolution of both decays by a non a priori method [1], their difference, D, is considered. The variance is computed for each point of D. A confidence interval is defined which allows a decision to be made as to the significan...

journal_title：Biochimie

authors： Genest D,Privat JP

更新日期：1984-09-01 00:00:00

abstract：:rBmTI-A is a recombinant serine protease inhibitor that belongs to the Kunitz-BPTI family and that was cloned from Rhipicephalus microplus tick. rBmTI-A has inhibitory activities on bovine trypsin, human plasma kallikrein, human neutrophil elastase and plasmin with dissociation constants in nM range. It is characteriz...

journal_title：Biochimie

authors： Bomediano Camillo LM,Ferreira GC,Duran AFA,da Silva FRS,Garcia W,Scott AL,Sasaki SD

更新日期：2020-12-24 00:00:00

abstract：:Sialidase catalyzes the removal of sialic acids from glycoconjugates. Recently, medaka sialidase Neu1 has been cloned and its enzymatic properties were investigated. Although enzymatic properties of this sialidase, such as optimal pH and substrate specificity, exhibits high similarity with human NEU1, Neu1 physiologic...

journal_title：Biochimie

authors： Ryuzono S,Takase R,Kamada Y,Ikenaga T,Chigwechokha PK,Komatsu M,Shiozaki K

更新日期：2017-04-01 00:00:00

abstract：:The purpose of the present study was to investigate the effect of a concentrated preparation (EPA 30) containing eicosapentaenoic acid (EPA, 20:5 n-3) and docosahexaenoic acid (DHA, 22:6 n-3) on the limiting desaturation steps of the polyunsaturated fatty acid biosynthesis in spontaneously hypertensive rats (SHR). Adu...

journal_title：Biochimie

authors： Narce M,Frenoux JM,Dardel V,Foucher C,Germain S,Delachambre MC,Poisson JP

更新日期：1997-02-01 00:00:00

abstract：:Gallium, a group IIIa metal salt, has been demonstrated to be an effective immunosuppressive agent. Gallium has also been shown to inhibit the production of inflammatory cytokines, such as IL-1beta, produced by macrophage-like cells in vitro. To further characterize the effects of gallium on the inflammatory process, ...

journal_title：Biochimie

authors： Panagakos FS,Kumar E,Venescar C,Guidon P

更新日期：2000-02-01 00:00:00

abstract：:The repressible Saccharomyces cerevisiae acid phosphatase (APase) coded by the PHO5 gene is a cell wall protein that follows the yeast secretory pathway. We had previously described the in vivo fate of a multicopy plasmid-encoded modified protein, lacking 15 out of 17 signal peptide amino acids. This modified protein ...

journal_title：Biochimie

authors： Silve S,Volland C,Hinnen A,Haguenauer-Tsapis R

更新日期：1990-02-01 00:00:00

abstract：:Two soluble forms of brain glutamate dehydrogenase isoproteins were inactivated by pyridoxal 5'-phosphate. Restoration of catalytic activity can be accomplished by dialysis and addition of an excess of cysteine or lysine. Spectral evidence is presented to indicate that the inactivation proceeds through Schiff base for...

journal_title：Biochimie

authors： Cho SW,Lee JE

更新日期：1996-01-01 00:00:00

abstract：:Kissing loop interactions (KLIs) are a common motif that is critical in retroviral dimerization, viroid replication, mRNA, and riboswitches. In addition, KLIs are currently used in a variety of biotechnology applications, such as in aptamer sensors, RNA scaffolds and to stabilize vaccines for therapeutics. Here we des...

journal_title：Biochimie

authors： Carr CE,Marky LA

更新日期：2019-02-01 00:00:00

abstract：:We present an approach for designing a knowledge-based system, called Sequence Acquisition In Context (SAIC), that will be able to cooperate with a biologist in the analysis of DNA sequences. The main task of the system is the acquisition of the expert knowledge that the biologist uses for solving ambiguities from gel...

journal_title：Biochimie

authors： Brézillon PJ,Zaraté P,Saci F

更新日期：1993-01-01 00:00:00

abstract：:Posttranscriptional gene regulation by small RNAs and its crucial impact on development, apoptosis, stem cell self-renewal and differentiation gained tremendous scientific attention since the discovery of RNA interference (RNAi) and microRNAs (miRNAs). However, in the last few years, many more examples for regulatory ...

journal_title：Biochimie

authors： Röther S,Meister G

更新日期：2011-11-01 00:00:00

abstract：:In most cancer cells, the ATP necessary for survival and proliferation is derived from glycolysis rather than from oxidative phosphorylations (OXPHOS) even when oxygen supply would be adequate to sustain them. This phenomenon, named "aerobic glycolysis" by Warburg many years ago, can now be explained by a mechanism up...

journal_title：Biochimie

authors： Hervouet E,Simonnet H,Godinot C

更新日期：2007-09-01 00:00:00

abstract：:This review discusses the regulation of a key controlling step in the initiation of protein synthesis, the binding of mRNA to ribosomes. Particular focus is given to the phosphorylation of the cap-binding factor, eIF-4E, and the role of this factor in the regulation of cell growth. ...

journal_title：Biochimie

authors： Sonenberg N

更新日期：1994-01-01 00:00:00

abstract：:Epigenetic mechanisms are likely to play a role in many complex diseases, the extent of which we only beginning to understand. COPD and asthma are two respiratory diseases subject to strong environmental influences depending on underlying genetic susceptibility. Epigenetic mechanisms such as DNA methylation, histone m...

journal_title：Biochimie

authors： Kabesch M,Adcock IM

更新日期：2012-11-01 00:00:00

abstract：:In this work, were studied the conditions of erucic acid (cis-docosenoic, n-9) shortening by using Rat liver mitochondrial preparations which were incubated in vitro with [14-14C] erucic acid (22:1), with inhibitors of the respiratory chain (rotenone, cyanide) or not, with activators of either the shortening reaction ...

journal_title：Biochimie

authors： Clouet P,Henninger C,Bezard J

更新日期：1982-10-01 00:00:00

abstract：:About 150 participants attended the symposium organised at the Palais de la Bourse in Bordeaux, France on September 22-23, 2017. Thirty speakers from all over the world delivered lectures covering selection processes, aptamer chemistry and innovative applications of these powerful tools that display major advantages o...

journal_title：Biochimie

authors： Toulmé JJ,Azéma L,Darfeuille F,Dausse E,Durand G,Paurelle O

更新日期：2018-02-01 00:00:00

abstract：:The vasoactive hormone bradykinin, its N-and C-terminal fragments and some structural analogues were studied by Circular Dichroism. Conformational features of the peptide can be detected by comparative analysis of the various CD spectra recorded as a function of aqueous pH, solvent and temperature. It is shown that th...

journal_title：Biochimie

authors： Lintner K,Fermandjian S,Regoli D

更新日期：1979-01-01 00:00:00

abstract：:NADH cytochrome b5 oxidoreductase (Ncb5or) protects β-cells against oxidative stress and lipotoxicity. The predominant phenotype of lean Ncb5or-null mouse is insulin-dependent diabetes due to β-cell death. This suggests the putative role of NCB5OR polymorphism in human diabetes. Therefore, we aimed to investigate the ...

journal_title：Biochimie

authors： Kálmán FS,Lizák B,Nagy SK,Mészáros T,Zámbó V,Mandl J,Csala M,Kereszturi E

更新日期：2013-07-01 00:00:00

abstract：:The structure difference between the free operator of the lac system d(GCTCACAAT).d(ATTGTGAGC) and the same operator complexed to the headpiece of the lac repressor has been investigated by 2-D-1H NMR spectroscopy in conjunction with molecular modelling in internal coordinates (JUMNA). The free and complexed operator ...

journal_title：Biochimie

authors： Gincel E,Lancelot G,Maurizot JC,Thuong NT,Vovelle F

更新日期：1994-01-01 00:00:00

abstract：:Nicotinate phosphoribosyltransferase (NaPRT, EC 2.4.2.11) catalyzes the conversion of nicotinate (Na) to nicotinate mononucleotide, the first reaction of the Preiss-Handler pathway for the biosynthesis of NAD(+). Even though NaPRT activity has been described to be responsible for the ability of Na to increase NAD(+) l...

journal_title：Biochimie

authors： Galassi L,Di Stefano M,Brunetti L,Orsomando G,Amici A,Ruggieri S,Magni G

更新日期：2012-02-01 00:00:00

abstract：:Glycogen was described as a temporal storage molecule in rhodococci, interconnecting lipids and carbon availability. The Rhodococcus jostii ADP-glucose pyrophosphorylase (ADP-GlcPPase) kinetic and regulatory properties support this role. Curiously, the enzyme uses glucosamine-1P as alternative substrate. Herein, we re...

journal_title：Biochimie

authors： Cereijo AE,Alvarez HM,Iglesias AA,Asencion Diez MD

更新日期：2020-09-01 00:00:00

abstract：:Four full-length cDNAs encoding the precursors of four K(+)-toxin-like peptides (named BmKK(1), BmKK(2), BmKK(3) and BmmKK(4), respectively) were first isolated from a venom gland cDNA library of the Chinese scorpion Buthus martensii Karsch. The deduced precursors of BmKK(1), BmKK(2) and BmKK(3) are all made of 54 ami...

journal_title：Biochimie

authors： Zeng XC,Peng F,Luo F,Zhu SY,Liu H,Li WX

更新日期：2001-09-01 00:00:00

abstract：:Amyloid beta protein (beta/A4) is deposited in senile plaques of patients with Alzheimer's disease. This protein is derived from a larger membrane-associated protein, termed amyloid precursor protein (APP). The constitutive processing of APP occurs at the central portion of beta/A4, resulting in the release of large N...

journal_title：Biochimie

authors： Shimokawa M,Nakamura K,Maruyama K,Tagawa K,Miyatake T,Sugita H,Ishiura S,Suzuki K

更新日期：1993-01-01 00:00:00

abstract：:The subunit composition of the myosin molecule which is built up from 3 pairs of identical polypeptide chains (2 heavy chains and 2 pairs of light chains), gives it the appearance of having symmetric structure. This homodimeric arrangement in the molecule is in fact asymmetric in its construction as a result of the na...

journal_title：Biochimie

authors： Schaub MC,Watterson JG

更新日期：1981-04-01 00:00:00

abstract：:In the intestine, NF-κB is the main transcription factor involved in the anti-inflammatory effect of glutamine and we previously demonstrated that glutamine via its conversion to glutamate diminished the p65 protein content in Caco-2/TC7 cell nuclei without affecting the stimulating effect of IL-1β on NF-κB [21]. Howe...

journal_title：Biochimie

authors： Lesueur C,Bôle-Feysot C,Bekri S,Husson A,Lavoinne A,Brasse-Lagnel C

更新日期：2012-03-01 00:00:00

abstract：:Secondary structure-forming DNA motifs have achieved infamy because of their association with a variety of human diseases and cancer. The 3rd FASEB summer conference on dynamic DNA structures focused on the mechanisms responsible for the instabilities inherent to repetitive DNA and presented many exciting and novel as...

journal_title：Biochimie

authors： Saini N,Zhang Y,Usdin K,Lobachev KS

更新日期：2013-02-01 00:00:00

abstract：:Recently a method was proposed which permits the extraction of the exact interatomic distance information from the measurement of the evolution of a single cross-peak relative to the mixing time in a NOESY experiment. This is performed through a careful multi-exponential analysis allowing the extraction of the relaxat...

journal_title：Biochimie

authors： Reisdorf C,Malliavin TE,Delsuc MA

更新日期：1992-09-01 00:00:00

abstract：:PA1b (Pea Albumin 1b) is a peptide toxin lethal for certain insects. This paper shows that the cultured insect cells Sf9 are sensitive to the toxin and display a high-affinity binding site for PA1b. Mammalian cells are not sensitive and no binding activity was detected. Signs of apoptosis of the Sf9 cells were observe...

journal_title：Biochimie

authors： Rahioui I,Laugier C,Balmand S,Da Silva P,Rahbe Y,Gressent F

更新日期：2007-12-01 00:00:00

abstract：:Endothelial nitric oxide synthase (eNOS) plays a crucial role in the regulation of a variety of cardiovascular functions. Many studies have shown that dietary n-3 polyunsaturated fatty acids (PUFAs) have beneficial effects on coronary atherosclerosis. However, the mechanisms of n-3 PUFAs regulation in eNOS activation ...

journal_title：Biochimie

authors： Li Q,Zhang Q,Wang M,Zhao S,Ma J,Luo N,Li N,Li Y,Xu G,Li J

更新日期：2007-01-01 00:00:00

abstract：:Genetic elements coding for proteins that present amino acid identity with the conserved motifs of retroviral reverse transcriptases constitute the retroid family. With the exception of reverse transcriptases encoded by mitochondrial plasmids of Neurospora, all reverse transcriptases have an absolute requirement for a...

journal_title：Biochimie

authors： Marquet R,Isel C,Ehresmann C,Ehresmann B

更新日期：1995-01-01 00:00:00