Abstract:
:Secondary structure-forming DNA motifs have achieved infamy because of their association with a variety of human diseases and cancer. The 3rd FASEB summer conference on dynamic DNA structures focused on the mechanisms responsible for the instabilities inherent to repetitive DNA and presented many exciting and novel aspects related to the metabolism of secondary structures. In addition, the meeting encompassed talks and posters on the dynamic structures that are generated during DNA metabolism including nicked DNA, Holliday junctions and RNA:DNA hybrids. New approaches for analysis and sequencing technologies put forth secondary structures and other DNA intermediates as vital regulators of a variety of cellular processes that contribute to evolution, polymorphisms and diseases.
journal_name
Biochimiejournal_title
Biochimieauthors
Saini N,Zhang Y,Usdin K,Lobachev KSdoi
10.1016/j.biochi.2012.10.005subject
Has Abstractpub_date
2013-02-01 00:00:00pages
117-23issue
2eissn
0300-9084issn
1638-6183pii
S0300-9084(12)00405-1journal_volume
95pub_type
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