Abstract:
:Datura stramonium contains a compound that impairs learning retention in mice. It has been purified to homogeneity and its structure has been established as that of a gamma-L-glutamyl-L-aspartate. The biological activity of this pseudodipeptide has been found to be identical with that of the corresponding synthetic one. It has also been compared to those of various synthetic di- and tripeptides containing L- and/or D-enantiomers of the constitutive amino acids. The results show that the activity is associated with a peptidic structure containing only one type of enantiomer.
journal_name
Biochimiejournal_title
Biochimieauthors
Schmitz-Bourgeois M,Amiri I,Reinbolt J,Boulanger Y,Ungerer Adoi
10.1016/0300-9084(88)90183-6subject
Has Abstractpub_date
1988-09-01 00:00:00pages
1179-84issue
9eissn
0300-9084issn
1638-6183pii
0300-9084(88)90183-6journal_volume
70pub_type
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