[Biosynthesis of phorcabiline, blue-green biliary pigment of Actias selene (Lepidoptera, Attacidae)].

abstract：:Isopentenyl adenosine derivatives can be found next to the anticodon (position 37) in tRNA from both the Bacteria and Eucarya domains. These modified nucleosides improve the efficiency of tRNA in translation, can increase and decrease translational fidelity, and make the tRNA less codon context sensitive. In bacteria ...

journal_title：Biochimie

authors： Persson BC,Esberg B,Olafsson O,Björk GR

更新日期：1994-01-01 00:00:00

abstract：:Virtually all brain circuits are physically embedded in a three-dimensional matrix of fibers that release 5-hydroxytryptamine (5-HT, serotonin). The density of this matrix varies across brain regions and cortical laminae, and it is altered in some mental disorders, including Major Depressive Disorder and Autism Spectr...

journal_title：Biochimie

authors： Janušonis S,Detering N

更新日期：2019-06-01 00:00:00

abstract：:In septic shock patients, alterations of plasma phospholipid fatty acid profile have never been described. The purpose of this monocentric, non-interventional, observational prospective study was to describe this fatty acid profile in the early phase of septic shock in intensive care unit. Thirty-seven adult patients ...

journal_title：Biochimie

authors： Rival T,Cinq-Frais C,Silva-Sifontes S,Garcia J,Riu B,Salvayre R,Genestal M,Caspar-Bauguil S

更新日期：2013-11-01 00:00:00

abstract：:The family of interferon regulatory transcription factors (IRF) participates in the virus-induced and dsRNA-stimulated transcriptional regulation of either type I IFN genes or a definite set of genes which can also be activated by IFN. In this review, we place emphasis on the role of IRF-3 that associates with the coa...

journal_title：Biochimie

authors： Bragança J,Civas A

更新日期：1998-08-01 00:00:00

abstract：:Nephropathy is one of the most frequent complications of chronic diabetes. The main reason for nephropathy despite being hyperglycemia, but it progresses even after good glycemic control has been achieved in diabetic patients. The effects of prior exposure to high blood glucose conditions depend upon the severity and ...

journal_title：Biochimie

authors： Kushwaha K,Sharma S,Gupta J

更新日期：2020-03-01 00:00:00

abstract：:Fluorometry using a substrate DNA labeled with a single fluorophore (6-carboxyfluorescein) at the 3'-end of the processed strand was shown to be a useful tool for monitoring DNA-binding and 3'-processing activities of HIV-1 and PFV integrases (INs). The DNA binding to either of the INs resulted in a fluorescence signa...

journal_title：Biochimie

authors： Anisenko A,Agapkina J,Zatsepin T,Yanvarev D,Gottikh M

更新日期：2012-11-01 00:00:00

abstract：:To elucidate the metabolic function of mRNA polyadenylation in Escherichia coli. we searched for a polyadenylate-binding protein as a potential mediator of the function of the poly(A) moiety. Using a nitrocellulose filter-binding assay and a Northwestern blot technique, a protein in the ribosomal supernatant fraction ...

journal_title：Biochimie

authors： Kalapos MP,Paulus H,Sarkar N

更新日期：1997-09-01 00:00:00

abstract：:After treatment of L929 cells, a murine fibrosarcoma line, with tumor necrosis factor (TNF), a nuclear kappa B-like transcription factor is rapidly induced as identified by gel shift mobility assays using the kappa B-responsive sequence of the immunoglobulin or interleukin-6 (IL-6) genes as a DNA probe. When induction...

journal_title：Biochimie

authors： Patestos NP,Haegeman G,Vandevoorde V,Fiers W

更新日期：1993-01-01 00:00:00

abstract：:Knowing the structure of a protein is essential to characterize its function and mechanism at the molecular level. Despite major advances in solving structures experimentally, most membrane protein native conformations remain unknown. This lack of available structures, along with the physical constraints imposed by th...

journal_title：Biochimie

authors： Postic G,Ghouzam Y,Gelly JC

更新日期：2015-08-01 00:00:00

abstract：:Kinetic parameters characterizing the catalytic activities of enzymes are typically investigated in dilute solutions. However, in reality, these reactions occur in cells that, in addition to water and ions, are full of other macromolecules including proteins, nucleic acids, lipids, and metabolites. Such a crowded envi...

journal_title：Biochimie

authors： Popielec A,Ostrowska N,Wojciechowska M,Feig M,Trylska J

更新日期：2020-09-01 00:00:00

abstract：:Thraustochytrium is a marine protist producing a specific profile of nutritionally important fatty acids, including very long chain polyunsaturated fatty acids (VLCPUFAs) docosahexaenoic acid (DHA, 22:6n-3), even chain saturated fatty acids (SFAs) palmitic acid (16:0), and odd chain SFAs pentadecanoic acid (15:0). To ...

journal_title：Biochimie

authors： Zhao X,Qiu X

更新日期：2018-01-01 00:00:00

abstract：:The major pterin in Tetrahymena pyriformis, strain W, earlier suggested to be L-threo-biopterin and named ciliapterin [1] is now identified as D-threo-neopterin (D-monapterin). This is the first example of a natural D-monapterin. This compound was characterized by its chromatographic behavior, its fluorescence propert...

journal_title：Biochimie

authors： Klein R,Tatischeff I,Tham G,Grolière CA

更新日期：1991-10-01 00:00:00

abstract：:Unlike most tonoplast ATPases, the vacuolar ATPase of Acer pseudoplatanus cells (Km = 0.4 mM) was strongly inhibited by vanadate (I50 = 10 microM). The inhibition was non-competitive. Chemicals usually added in the reaction mixture either increase (NH+4, K+) or decrease (Na+, EDTA) the ATPase inhibition. However, thes...

journal_title：Biochimie

authors： Montrichard F,Pugin A,Gaudemer Y

更新日期：1989-07-01 00:00:00

abstract：:So far, no efficient affinity chromatography for CCK receptor purification has been reported that prevented obtention of sequenceable amounts of purified receptor. In this work, 10% of plasma membrane receptor sites were specifically cross-linked with the photoreactive cleavable agonist 125I-ASD-[Thr28, Ahx31]-CCK-25-...

journal_title：Biochimie

authors： Dufresne M,Poirot S,Jimenez J,Vaysse N,Fourmy D

更新日期：1992-02-01 00:00:00

abstract：:In 1998, the concept of "green chemistry" was established through twelve principles with the aim of improving the eco-efficiency of chemical processes and to judge, whether or not, a chemical process is sustainable. Currently, numerous processes do not obey to most of these principles (large energy usage, formation of...

journal_title：Biochimie

authors： Durand E,Lecomte J,Villeneuve P

更新日期：2016-01-01 00:00:00

abstract：:We have cloned a homologue of the translationally controlled tumor protein (TCTP) from the buccal gland of Lampetra japonica according to information from a cDNA library and primary analysis of expressed sequence tags. Sequence analysis of L. japonica TCTP showed that it had two signature regions of high sequence homo...

journal_title：Biochimie

authors： Sun J,Wu Y,Wang J,Ma F,Liu X,Li Q

更新日期：2008-11-01 00:00:00

abstract：:Sm and Sm-like (Lsm) proteins are considered as an evolutionary conserved family involved in RNA metabolism in organisms from bacteria and archaea to human. Currently, the function of Sm-like archaeal proteins (SmAP) is not well understood. Here, we report the crystal structures of SmAP proteins from Sulfolobus acidoc...

journal_title：Biochimie

authors： Lekontseva N,Mikhailina A,Fando M,Kravchenko O,Balobanov V,Tishchenko S,Nikulin A

更新日期：2020-08-01 00:00:00

abstract：:High glucose (HG)-induced podocyte injury contributes to the pathogenesis of diabetic nephropathy, a severe complication of diabetes. Bromodomain-containing protein 4 (BRD4) has emerged as a critical regulator for cell injury. However, whether BRD4 participates in HG-induced podocyte injury remains unclear. In this st...

journal_title：Biochimie

authors： Zuo H,Wang S,Feng J,Liu X

更新日期：2019-10-01 00:00:00

abstract：:Epigenetic alterations are involved in every step of carcinogenesis. The development of chromatin-modifying agents (CMAs) has provided the ability to fight cancer by reversing these alterations. Currently, four CMAs have been approved for cancer treatment; two DNA demethylating agents and two deacetylase inhibitors. A...

journal_title：Biochimie

authors： Seidel C,Florean C,Schnekenburger M,Dicato M,Diederich M

更新日期：2012-11-01 00:00:00

abstract：:The term 'RNA editing' was used for the first time in 1986 to describe the process of uridylate insertion into trypanosomal mitochondrial transcripts. Since then, the term has been used more generally to describe a large variety of processes involving base insertions, deletions and conversions that generate RNAs with ...

journal_title：Biochimie

authors： Blanc V,Jordana X,Litvak S,Araya A

更新日期：1996-01-01 00:00:00

abstract：:This paper reviews recent data on the adenylate cyclase system of the yeast Saccharomyces cerevisiae. Since the discovery of yeast adenylate cyclase mutants and the possibility of molecular biological analysis, adenylate cyclase and the subsequent steps in the cAMP cascade have become subject of intense investigation....

journal_title：Biochimie

authors： Jacquet M,Camonis J

更新日期：1985-01-01 00:00:00

abstract：:A novel bgl1 gene, encoding GH3 family β-glucosidase from Penicillium verruculosum (PvBGL), was cloned and heterologously expressed in P. canescens RN3-11-7 (niaD-) strain under the control of the strong xylA gene promoter. The recombinant rPvBGL was purified and their properties were studied in comparison with those ...

journal_title：Biochimie

authors： Volkov PV,Rozhkova AM,Zorov IN,Sinitsyn AP

更新日期：2020-01-01 00:00:00

abstract：:Several inositol isomers and in particular myo-inositol (MI) and D-chiro-inositol (DCI), were shown to possess insulin-mimetic properties and to be efficient in lowering post-prandial blood glucose. In addition, abnormalities in inositol metabolism are associated with insulin resistance and with long term microvascula...

journal_title：Biochimie

authors： Croze ML,Soulage CO

更新日期：2013-10-01 00:00:00

abstract：:Nicotinate phosphoribosyltransferase (NaPRT, EC 2.4.2.11) catalyzes the conversion of nicotinate (Na) to nicotinate mononucleotide, the first reaction of the Preiss-Handler pathway for the biosynthesis of NAD(+). Even though NaPRT activity has been described to be responsible for the ability of Na to increase NAD(+) l...

journal_title：Biochimie

authors： Galassi L,Di Stefano M,Brunetti L,Orsomando G,Amici A,Ruggieri S,Magni G

更新日期：2012-02-01 00:00:00

abstract：:Affinity chromatography on cross-linked starch affords a simple and rapid procedure for alpha-amylases (EC 3.2.1.1.) purification. When starch is cross-linked in alkaline medium by epichlorhydrin in the conditions described, the insoluble polysaccharide obtained is able to retain specifically the alpha-amylase which i...

journal_title：Biochimie

authors： Weber M,Foglietti MJ,Percheron F

更新日期：1976-01-01 00:00:00

abstract：:A 3-D model of the tyrosylable tRNA-like domain of the genomic brome mosaic virus RNAs was built by computer modelling based on solution probing of the molecule with different chemical and enzymatic reagents. This model encompasses four major structural domains, including two peculiar substructures oriented perpendicu...

journal_title：Biochimie

authors： Felden B,Florentz C,Westhof E,Giegé R

更新日期：1993-01-01 00:00:00

abstract：:In the recent years, we have provided evidence that Tumor Protein 53-Induced Nuclear Protein 1 (TP53INP1) is a key stress protein with antioxidant-associated tumor suppressive function. The TP53INP1 gene, which is highly conserved in mammals, is over-expressed during stress responses including inflammation. This gene ...

journal_title：Biochimie

authors： Saadi H,Seillier M,Carrier A

更新日期：2015-11-01 00:00:00

abstract：:Catalase (E.C 1.11.1.6) was purified from leaves of Zandedeschia aethiopica to apparent homogeneity by a one-step hydrophobic interaction chromatography on a phenyl Sepharose CL-4B column. The purified enzyme preparation was obtained with a final recovery of enzyme activity of about 61% and a specific activity of 146 ...

journal_title：Biochimie

authors： Trindade H,Karmali A,Pais MS

更新日期：1988-12-01 00:00:00

abstract：:Some physico-chemical properties of R140G and K141Q mutants of human small heat shock protein HspB1 associated with hereditary peripheral neuropathy were analyzed. Mutation K141Q did not affect intrinsic Trp fluorescence and interaction with hydrophobic probe bis-ANS, whereas mutation R140G decreased both intrinsic fl...

journal_title：Biochimie

authors： Nefedova VV,Datskevich PN,Sudnitsyna MV,Strelkov SV,Gusev NB

更新日期：2013-08-01 00:00:00

abstract：:Wheat germ lysate was used as a model system for in vitro translation. We show that an increase of the exchange surface between the reaction mixture and the atmosphere enhanced the amount of incorporated cysteine, indicating that early arrest of protein synthesis previously observed in such a system was due to oxygen ...

journal_title：Biochimie

authors： Luciani N,Hess K,Belleville F,Nabet P

更新日期：1995-01-01 00:00:00