Abstract:
:As a first step to investigate the functional activity of gypsy virus-like particles (VLPs) we explored the possibility of preservation of its VLP in extracellular form. The preparations containing extracellular gypsy VLP from Drosophila melanogaster and D. virilis were obtained. Full-length polyA+ RNA and polyA+ RNA-DNA complexes of gypsy were observed in both preparations. The polypeptides with some specificity to gypsy nucleic acids were identified in the obtained VLP preparations. These data accompanied by morphological characteristics of samples testify the presence of intact gypsy VLP in cultured media both from D. melanogaster and D. virilis cultivated cells.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Syomin BV,Kandror KV,Semakin AB,Tsuprun VL,Stepanov ASdoi
10.1016/0014-5793(93)81358-7subject
Has Abstractpub_date
1993-06-01 00:00:00pages
285-8issue
3eissn
0014-5793issn
1873-3468pii
0014-5793(93)81358-7journal_volume
323pub_type
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