Abstract:
:Incubation of human thrombocytes in the presence of [3H]palmitic acid leads to incorporation of this fatty acid into the alpha subunit of Gs as described [Linder et al., Proc. Natl. Acad. Sci. USA 90 (1993) 3675-3679; Degtyarev et al., Biochemistry 32 (1993) 8057-8061] but also into the catalyst of adenylyl cyclase which has not been recognized before. Treatment of labeled membranes with hydroxylamine released the label from both components. Label incorporated into the catalyst could be identified as [3H]palmitate. At the same time chemical deacylation caused partial loss of adenylyl cyclase activity.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Mollner S,Beck K,Pfeuffer Tdoi
10.1016/0014-5793(95)00864-6subject
Has Abstractpub_date
1995-09-11 00:00:00pages
241-4issue
3eissn
0014-5793issn
1873-3468pii
0014-5793(95)00864-6journal_volume
371pub_type
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