Abstract:
:Analysis of the amino acid sequence of bovine brain myelin proteolipid reveals not only extensive internal homology, but also homology with portions of the myelin basic protein, the peripheral nerve myelin protein, Po, and with the small proteolipid subunit of mitochondrial ATP synthase. These results suggest that the myelin proteolipid gene has been constructed from a small number of genetic elements, and that these elements are also found in non-myelin proteins. Furthermore, the proteolipid appears to have evolved by acquisition of elements from a 'gene pool' over a period of time, rather than by a simple duplication mechanism.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Laursen RA,Samiullah M,Lees MBdoi
10.1016/0014-5793(83)80732-7subject
Has Abstractpub_date
1983-09-05 00:00:00pages
71-4issue
1eissn
0014-5793issn
1873-3468pii
0014-5793(83)80732-7journal_volume
161pub_type
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