Abstract：
:The multicellular epithelial organs in Proteus anguinus, which Bugnion (1873) assumed to be developing neuromasts, have been analyzed by light- and electron-microscopy. Their fundamental structure consists of single ampullae with sensory and accessory cells with apical parts that extend into the pit of the ampulla, and of a short jelly-filled canal connecting the ampulla pit with the surface of the skin. The organs are located intra-epithelially and are supported by a tiny dermal papilla. The cell elements of sensory epithelium are apically linked together by tight junctions. The free apical surface of the sensory cell bears several hundred densely packed stereocilia-like microvilli whereas the basal surface displays afferent neurosensory junctions with a pronounced round synaptic body. The compact uniform organization of the apical microvillous part shows a hexagonal pattern. A basal body was found in some sensory cells whereas a kinocilium was observed only in a single cell. The accessory cells have their free surface differentiated in a sparsely distributed and frequently-forked microvilli. The canal wall is built of two or three layers of tightly coalescent flat cells bordering on the lumen with branching microvilli. The ultrastructure of the content of the ampulla pit is presented. In the discussion stress is laid on the peculiarities of the natural history of Proteus anguinus that support the view that the morphologically-identified ampullary organs are electroreceptive. The structural characteristics of ampullary receptor cells are dealt with from the viewpoint of functional morphology and in the light of evolutionary hypotheses of ampullary organs.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Istenic L,Bulog Bdoi
10.1007/BF00217865subject
Has Abstractpub_date
1984-01-01 00:00:00pages
393-402issue
2eissn
0302-766Xissn
1432-0878journal_volume
235pub_type
杂志文章abstract：:In this study, we demonstrate the role of M cells in uptake of poly(D-L-lactic-co-glycolic acid) (PLGA) microspheres and transport into rabbit Peyer's patches. Microspheres 1 to 10 microns in diameter composed of 50:50 lactic acid:glycolic acid were instilled into intestinal segments containing jejunal or ileal Peyer'...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318501
更新日期：1995-02-01 00:00:00
abstract：:Numerous macrophages were found aggregated in the lamina propria at the tips of villi in the small intestine of guinea pigs. These macrophages extended their pseudopodia into the epithelial lining and internalized fragments of effete enterocytes in their phagosomes. The epithelium of the villus tips was found to be in...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF02913723
更新日期：1993-03-01 00:00:00
abstract：:Tenidap is a structurally novel antirheumatic agent with anti-inflammatory and analgesic properties. Previous studies have shown that tenidap is able to inhibit the production and action of cytokines such as interleukin-1, interleukin-6 (IL-6) and tumour necrosis factor alpha. However, the mechanisms by which tenidap ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050810
更新日期：1997-05-01 00:00:00
abstract：:An improved technique for fluorescent labelling of heavy meromyosin has made it possible to detect on a light microscopic level the cellular sites of actin localization. Rabbit heavy meromyosin (HMM) was labelled with fluorescein isothiocyanate so that the actin binding site was protected during the reaction. The spec...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224134
更新日期：1975-08-27 00:00:00
abstract：:The so-called 'basement membrane' of arthropod compound eyes is known to be of heterogeneous origin (Odselius and Eloffson 1981). A major contribution in Diptera with open rhabdoms is provided by a pigmented component which lies at the basal end of the extracellular space of each ommatidium and fills it, the glial plu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222184
更新日期：1983-01-01 00:00:00
abstract：:The solute carrier (SLC) group of membrane transport proteins includes about 400 members organized into more than 50 families. The SLC family that comprises nucleoside-sugar transporters is referred to as SLC35. One of the members of this family is SLC35F1. The function of SLC35F1 is still unknown; however, recent stu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03008-8
更新日期：2019-08-01 00:00:00
abstract：:We used immunohistochemistry to identify cells present in pituitary allografts in the hamster. Hypophyses removed from neonatal hamsters or adenohypophyses removed from adult females were placed beneath renal capsules of hypophysectomized adult females. Serum PRL, LH, and GH concentrations were measured at two, five a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215467
更新日期：1988-01-01 00:00:00
abstract：:The thyroid cells of the cream hamster, characterized by abundance of microtubules and stratification of the organelles, undergo a particular evolution when the animals grow older. These changes are characterized by an increase of the number of lysosomes which in extreme cases become so prominent that they occupy the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215124
更新日期：1976-02-06 00:00:00
abstract：:Tissue lectins appear to be involved in a broad range of physiological processes, as reflected for the members of the family of galectins by referring to them as adhesion/growth-regulatory effectors. In order to clarify the significance of galectin presence, key challenges are to define their binding partners and the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2931-x
更新日期：2019-03-01 00:00:00
abstract：:Blue-green fluorescent subependymal cells with intraventricular processes were shown by the fluorescent histochemical method to be distributed from the preoptic recess to the infundibular recess of the frog hypothalamus. Electron microscopy revealed at least two types of CSF-contacting subependymal cells, type 1 conta...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221791
更新日期：1977-01-20 00:00:00
abstract：:Exocytotic release of the secretory granules of the endocrine cells in the midgut of a cockroach, Periplaneta americana, was studied by means of fixation with tannic acid in combination with glutaraldehyde and osmium tetroxide. A sequence of images indicative of exocytosis suggests the following steps in this process:...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213851
更新日期：1982-01-01 00:00:00
abstract：:Cell degeneration, as a phenomenon accompanying developmental processes, was originally described over a century ago. Apoptosis, a term introduced approximately three decades ago, has occupied investigators particularly with respect to cell and tissue kinetics, emphasizing its role in the disposal of supernumerary, ma...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410000227
更新日期：2000-07-01 00:00:00
abstract：:Macrophages are present throughout the anterior pituitary gland. However, the features and function of macrophages in the gland are poorly understood. Recent studies have indicated that there are two main macrophage classes: M1 (classically activated) and M2 (alternatively activated). In this study, we examine whether...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2564-x
更新日期：2017-05-01 00:00:00
abstract：:Progenitor stem cells have been identified, isolated and characterized in numerous tissues and organs. However, their therapeutic potential and the use of these stem cells remain elusive except for a few progenitor cells from bone marrow, umbilical cord blood, eyes and dental pulp. The use of bone marrow-derived hemat...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-012-1471-z
更新日期：2012-10-01 00:00:00
abstract：:Luteinizing hormones-releasing hormone (LHRH), vasopressin, and corticotropin systems were examined by immunocytochemical methods in male rats 2 to 20 days after deafferentation of the basal hypothalamus. Axonal degeneration of the vasopressin system (whose perikarya lie rostral to the island) and the corticotropin sy...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210157
更新日期：1981-01-01 00:00:00
abstract：:Apoptosis is a form of programmed cell death that occurs in neurons during development of the nervous system and may also be a prominent form of neuronal death in chronic neurodegenerative disorders such as Alzheimer's and Parkinson's diseases. Recent findings also implicate apoptosis in neuronal degeneration after is...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004419900154
更新日期：2000-07-01 00:00:00
abstract：:To investigate the control of the timing in the epithelio-mesenchymal transformation of the neural crest into a migrating population, neural anlagen (neural tube plus crest) were isolated from 2-day quail embryos by proteases in the presence of CA++ and explanted onto substrates favourable for neural crest cell migrat...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218011
更新日期：1985-01-01 00:00:00
abstract：:Notch signaling is evolutionarily conserved from Drosophila to human. It plays critical roles in neural stem cell maintenance and neurogenesis in the embryonic brain as well as in the adult brain. Notch functions greatly depend on careful regulation and cross-talk with other regulatory mechanisms. Deregulation of Notc...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2641-9
更新日期：2018-01-01 00:00:00
abstract：:The surface of carp oral mucosa is characterized by various patterns of microridges about 0.3 micron wide, 0.1 micron high, and of various lengths. To elucidate the derivation and function of these microridges, the oral epithelium was examined by light- and electron microscopy. Microridges were present only on the sur...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214002
更新日期：1988-03-01 00:00:00
abstract：:The cellular response of non-neuronal elements of the pyramidal cell layer of the rat hippocampus, especially the area CA3, was observed electron microscopically following destruction of this formation by means of intraventricular administration of kainic acid (KA). The neuroglial cell types responding to the KA-induc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00238652
更新日期：1981-01-01 00:00:00
abstract：:Testicular neoplasms occur spontaneously in androgen insensitive mice with testicular feminization (tfm/y); they are composed of Leydig cells, lipid-laden cells, fibroblastlike cells, and macrophages. The small Leydig cells in the periphery of the tumor are structurally similar to nontumorous tfm/y Leydig cells, where...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234172
更新日期：1980-01-01 00:00:00
abstract：:Dietary restriction (DR) retards physical growth, resulting in small body size, reduced liver weight and reduced number of hepatocytes in rats. We examined the effects of DR on proliferation and apoptosis of hepatocytes during development and explained these changes subcellularly using immunohistochemistry for bromode...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900126
更新日期：2000-03-01 00:00:00
abstract：:Transcriptome profiling of the pineal gland has revealed night/day differences in the expression of a major fraction of the genes active in this tissue, with two-thirds of these being nocturnal increases. A set of over 600 transcripts exhibit two-fold to >100-fold daily differences in abundance. These changes appear t...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-010-1094-1
更新日期：2011-04-01 00:00:00
abstract：:The secretory activity in the subcommissural organ (SCO) of the sheep and cow was examined by means of lectin histochemistry and cytochemistry. Among the various lectins tested. Concanavalin A (Con A) revealed glycoproteins rich in mannosyl residues in the rough endoplasmic reticulum of ependymal and hypendymal cells....
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222295
更新日期：1988-08-01 00:00:00
abstract：:The dorsal root ganglion (DRG) and dorsal horn of the spinal cord are areas through which primary afferent information passes enroute to the brain. Previous studies have reported that, during normal neuronal activity, the regional distribution of a second messenger, diacylglycerol (DG), which is derived from phosphoin...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0219-z
更新日期：2006-10-01 00:00:00
abstract：:Using a somatostatin-gold conjugate of known biological activity, high affinity binding sites for this neuropeptide were visualized at cellular resolution on cultured diencephalic astrocytes and on frozen sections of the rat diencephalon. Binding could be completely suppressed in competition experiments with surplus u...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318767
更新日期：1991-02-01 00:00:00
abstract：:The treatment of isolated protoplasmic strands of Physarum polycephalum with 2.5% ethanol in a physiological salt solution under isometric conditions induces the formation of a large amount of mostly longitudinally organized actomyosin fibrils in the endoplasmic channel, a region normally free of actomyosin fibrils. T...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218017
更新日期：1985-01-01 00:00:00
abstract：:The purpose of this study was to determine the cellular distribution and degradation in rat liver following intravenous injection of superparamagnetic iron oxide nanoparticles used for magnetic resonance imaging (NC100150 Injection). Relaxometric and spectrophotometric methods were used to determine the concentration ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0884-8
更新日期：2004-06-01 00:00:00
abstract：:The olfactory sensilla on the maxillary palp tip of Locusta migratoria (L.) resemble the surrounding contact chemoreceptors in general morphology. The perforated peg has a thicker wall than is commonly found in olfactory sensilla. The form and position of the sensilla are considered in relation of the olfactory functi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219899
更新日期：1977-11-07 00:00:00
abstract：:Interstitial cells in the myenteric plexus and the deep muscular plexus of the small intestine of the c-kit mutant rats (Ws/Ws) and their normal siblings (+/+) were studied. c-Kit immunoreactivity was detected in two regions corresponding to the myenteric plexus and the deep muscular plexus in the jejunum of +/+ rats,...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051119
更新日期：1998-08-01 00:00:00
