abstract：:Teleost fish exhibit extraordinary cognitive skills that are comparable to those of mammals and birds. Kin recognition based on olfactory and visual imprinting requires neuronal circuits that were assumed to be necessarily dependent on the interaction of mammalian amygdala, hippocampus, and isocortex, the latter being...

journal_title：Cell and tissue research

authors： Gerlach G,Wullimann MF

更新日期：2021-01-30 00:00:00

abstract：:Honeybees are extensively used to study olfactory learning and memory processes thanks to their ability to discriminate and remember odors and because of their advantages for optophysiological recordings of the circuits involved in memory and odor perception. There are evidences that the encoding of odors in areas of ...

journal_title：Cell and tissue research

authors： Marachlian E,Klappenbach M,Locatelli F

更新日期：2021-01-29 00:00:00

abstract：:This study aimed to characterize porcine Achilles tendon (PAT) in terms of its structural components, vascularity, and resident tendon cells. We found that PAT is composed of a paratenon sheath, a core of fascicles, and an endotenon/interfascicular matrix (IFM) that encases the fascicle bundles. We analyzed each of th...

journal_title：Cell and tissue research

authors： Zhang J,Li F,Williamson KM,Tan S,Scott D,Onishi K,Hogan MV,Wang JH

更新日期：2021-01-26 00:00:00

abstract：:Spinal cord injury (SCI) is a major cause of paralysis, disability and even death in severe cases. Lithium has neuroprotective effects on SCI, while the underlying mechanisms remain obscure. In the present study, we established a SCI rat model, which subsequently received lithium treatment. Results displayed that lith...

journal_title：Cell and tissue research

authors： Wang F,Chang S,Li J,Wang D,Li H,He X

更新日期：2021-01-19 00:00:00

abstract：:Human endothelial progenitor cells (EPCs) were isolated from cord blood samples and enriched by magnetic activated cell sorting method based on the CD133 marker. Cells were incubated with different doses of bacterial lipopolysaccharide, ranging from 2, 5, 10, 50, 100, 200, 250, 500, to 1000 µg/ml, for 48 h. The cell s...

journal_title：Cell and tissue research

authors： Heidarzadeh M,Avcı ÇB,Saberianpour S,Ahmadi M,Hassanpour M,Bagheri HS,Rezaie J,Talebi M,Roodbari F,Sokullu E,Darabi M,Rahbarghazi R

更新日期：2021-01-18 00:00:00

abstract：:Variations in gene expression patterns represent a powerful source of evolutionary innovation. In a rodent living about 70 million years ago, a genomic accident led an immune formyl peptide receptor (FPR) gene to hijack a vomeronasal receptor regulatory sequence. This gene shuffling event forced an immune pathogen sen...

journal_title：Cell and tissue research

authors： Boillat M,Carleton A,Rodriguez I

更新日期：2021-01-16 00:00:00

abstract：:Olfactory marker protein (OMP) was first described as a protein expressed in olfactory receptor neurons (ORNs) in the nasal cavity. In particular, OMP, a small cytoplasmic protein, marks mature ORNs and is also expressed in the neurons of other nasal chemosensory systems: the vomeronasal organ, the septal organ of Mas...

journal_title：Cell and tissue research

authors： Dibattista M,Al Koborssy D,Genovese F,Reisert J

更新日期：2021-01-15 00:00:00

abstract：:Communication between individuals is critical for species survival, reproduction, and expansion. Most terrestrial species, with the exception of humans who predominantly use vision and phonation to create their social network, rely on the detection and decoding of olfactory signals, which are widely known as pheromone...

journal_title：Cell and tissue research

authors： Tirindelli R

更新日期：2021-01-12 00:00:00

abstract：:Osteoarthritis (OA) is the most common joint disease with an unsatisfactory therapy outcome and characterized by the degradation of articular cartilage and synovial inflammation. Here, we isolated bone marrow mesenchymal stem cells (BMSCs) from rat's bone marrow and BMSC-derived exosome (BMSCs-Exo) from BMSCs successf...

journal_title：Cell and tissue research

authors： Wang R,Xu B

更新日期：2021-01-06 00:00:00

abstract：:Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating the olfactory mucosa. Different odorants, or different ...

journal_title：Cell and tissue research

authors： Kurian SM,Naressi RG,Manoel D,Barwich AS,Malnic B,Saraiva LR

更新日期：2021-01-06 00:00:00

abstract：:While Th1 and Th17 T effector cells are pathogenic drivers of glomerulonephritis (GN), regulatory T cells (Tregs) potently protect from renal tissue injury. Recently, it has become evident that different Treg subtypes exist. Among these are lineage specific Treg1 and Treg17 cells, which are specialized to down regulat...

journal_title：Cell and tissue research

authors： Herrnstadt GR,Steinmetz OM

更新日期：2020-12-14 00:00:00

abstract：:Phenotype transition of vascular smooth muscle cells (VSMCs) is implicated in vascular diseases. Angiotensin-converting enzyme 2 (ACE2) is a perspective cardiovascular target due to its ability of converting angiotensin (Ang II) to Ang (1-7). Our group recently showed that ACE2 can regulate the function of endothelial...

journal_title：Cell and tissue research

authors： Wang J,Li J,Cheng C,Liu S

更新日期：2020-12-01 00:00:00

abstract：:The acrosome is a special organelle that develops from the Golgi apparatus and the endolysosomal compartment in the spermatids. Centromere protein E (CENP-E) is an essential kinesin motor in chromosome congression and alignment. This study is aimed at investigating the roles and mechanisms of kinesin-7 CENP-E in the f...

journal_title：Cell and tissue research

authors： She ZY,Yu KW,Wei YL,Zhong N,Lin Y

更新日期：2020-11-25 00:00:00

abstract：:Fueled by the discovery of head regeneration in triclads (planarians) two and a half centuries ago, flatworms have been the focus of regeneration research. But not all flatworms can regenerate equally well and to obtain a better picture of the characteristics and evolution of regeneration in flatworms other than plana...

journal_title：Cell and tissue research

authors： Schadt T,Prantl V,Grosbusch AL,Bertemes P,Egger B

更新日期：2020-11-07 00:00:00

abstract：:The burrower bug Scaptocoris castanea is an important soybean and pasture pest in Brazil, with an underground habit feeding directly on the sap of the roots. Underground habit hinders control and knowledge of the biology and physiology of this pest. This study describes the anatomy, histology, ultrastructure and symbi...

journal_title：Cell and tissue research

authors： Cossolin JFS,Lopes DRG,Martínez LC,Santos HCP,Fiaz M,Pereira MJB,Vivan LM,Mantovani HC,Serrão JE

更新日期：2020-11-01 00:00:00

abstract：:A tissue-engineered heart valve can be an alternative to a prosthetic valve in heart valve replacement; however, it is not fully efficient in terms of long-lasting functionality, as leaflets in engineered valves do not possess the trilayered native leaflet structure. Previously, we developed a flat, trilayered, orient...

journal_title：Cell and tissue research

authors： Jana S,Lerman A

更新日期：2020-11-01 00:00:00

abstract：:Glial cell line-derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote dopamine uptake within midbrain dopaminergic neurons. Since its discover...

journal_title：Cell and tissue research

authors： Cintrón-Colón AF,Almeida-Alves G,Boynton AM,Spitsbergen JM

更新日期：2020-10-01 00:00:00

abstract：:The amygdala is a central hub for fear learning assessed by Pavlovian fear conditioning. Indeed, the prevailing hypothesis that learning and memory are mediated by changes in synaptic strength was shown most convincingly at thalamic and cortical afferents to the lateral amygdala. The neurotrophin brain-derived neurotr...

journal_title：Cell and tissue research

authors： Meis S,Endres T,Lessmann V

更新日期：2020-10-01 00:00:00

abstract：:The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) comprise a group of four homologous and potent growth factors that includes GDNF, neurturin (NRTN), artemin (ARTN), and persephin (PSPN). The survival, growth, and mitotic activities of the GFLs are conveyed by a single receptor tyrosine kina...

journal_title：Cell and tissue research

authors： Donnelly CR,Pierchala BA

更新日期：2020-10-01 00:00:00

abstract：:The enteric nervous system (ENS) controls gastrointestinal functions. In large mammals' intestine, it comprises an inner (ISP) and outer (OSP) submucous plexus and a myenteric plexus (MP). This study quantifies enteric neurons in the ISP, OSP, and MP of the pig ascending (AC) and descending colon (DC) using the HuC/D,...

journal_title：Cell and tissue research

authors： Mazzoni M,Caremoli F,Cabanillas L,de Los Santos J,Million M,Larauche M,Clavenzani P,De Giorgio R,Sternini C

更新日期：2020-09-23 00:00:00

abstract：:Extracellular matrix (ECM) plays a dynamic role during tissue development and re-growth. Body part regeneration efficiency relies also on effective ECM remodelling and deposition. Among invertebrates, echinoderms are well known for their striking regenerative abilities since they can rapidly regenerate functioning com...

journal_title：Cell and tissue research

authors： Ferrario C,Czarkwiani A,Dylus DV,Piovani L,Candia Carnevali MD,Sugni M,Oliveri P

更新日期：2020-09-01 00:00:00

abstract：:The submandibular gland (SMG) of newborn mice has no mature acini but has the rudiments of acini called terminal tubules (TT). The TT are composed of TT cells with dark secretory granules and proacinar cells with lighter secretory granules, the latter being considered the immediate precursor of mature acinar cells. TT...

journal_title：Cell and tissue research

authors： Nakata H,Terakawa J,Horike SI,Daikoku T,Iseki S

更新日期：2020-08-01 00:00:00

abstract：:Periodontal ligament (PDL) stem cell properties are critical in the periodontal tissue regeneration for periodontitis. Previously, we have demonstrated that cigarette smoking attenuates PDL-derived stem cell (PDLSC) regenerative properties. Here, we report the findings on the regenerative properties of human PDLSCs wi...

journal_title：Cell and tissue research

authors： Ng TK,Chen CB,Xu C,Xu Y,Yao X,Huang L,Liang JJ,Cheung HS,Pang CP,Huang Y

更新日期：2020-07-01 00:00:00

abstract：:Post-translational glycosylation of proteins with O-linked β-N-acetylglucosamine (O-GlcNAcylation) and changes of galectin expression profiles are essential in many cellular stress responses. We examine this regulation in the liver tissue of hibernating thirteen-lined ground squirrels (Ictidomys tridecemlineatus) repr...

journal_title：Cell and tissue research

authors： Jariwala KA,Sherazi AA,Tazhitdinova R,Shum K,Guevorguian P,Karagiannis J,Staples JF,Timoshenko AV

更新日期：2020-07-01 00:00:00

abstract：:Terrestrial hermit crabs of the genus Coenobita display strong behavioral responses to volatile odors and are attracted by chemical cues of various potential food sources. Several aspects of their sense of aerial olfaction have been explored in recent years including behavioral aspects and structure of their periphera...

journal_title：Cell and tissue research

authors： Polanska MA,Kirchhoff T,Dircksen H,Hansson BS,Harzsch S

更新日期：2020-06-01 00:00:00

abstract：:The LIM homeodomain transcription factor Lmx1a shows a dynamic expression in the developing mouse ear that stabilizes in the non-sensory epithelium. Previous work showed that Lmx1a functional null mutants have an additional sensory hair cell patch in the posterior wall of a cochlear duct and have a mix of vestibular a...

journal_title：Cell and tissue research

authors： Nichols DH,Bouma JE,Kopecky BJ,Jahan I,Beisel KW,He DZZ,Liu H,Fritzsch B

更新日期：2020-06-01 00:00:00

abstract：:Acute necrotizing pancreatitis (ANP) is a common gastrointestinal cause of emergency admissions in dogs and humans and can lead to a systemic inflammatory response syndrome resulting in multiple organ dysfunction syndrome. Among the various complications associated with ANP, acute lung injury (ALI) or acute respirator...

journal_title：Cell and tissue research

authors： Vrolyk V,Singh B

更新日期：2020-05-01 00:00:00

abstract：:Ependymal cells located above the ventricular zone of the lateral, third, and fourth ventricles and the spinal cord are thought to form part of the adult neurogenic niche. Many studies have focused on ependymal cells as potential adult neural stem/progenitor cells. To investigate the functions of ependymal cells, a si...

journal_title：Cell and tissue research

authors： Horiguchi K,Yoshida S,Hasegawa R,Takigami S,Ohsako S,Kato T,Kato Y

更新日期：2020-03-01 00:00:00

abstract：:Digital dermatitis (DD), a common ulcerative disease of the bovine foot causing lameness and reducing productivity and animal welfare, is associated with infection by spirochete Treponema bacteria. Topical tetracycline, the most common treatment, has inconsistent cure rates; therefore, new therapeutic options are need...

journal_title：Cell and tissue research

authors： Watts KM,Lahiri P,Arrazuria R,De Buck J,Knight CG,Orsel K,Barkema HW,Cobo ER

更新日期：2020-02-01 00:00:00

abstract：:Kisspeptin is a hypothalamic neuropeptide, which acts directly on gonadotropin-releasing hormone (GnRH)-secreting neurons via its cognate receptor (GPR54 or Kiss-R) to stimulate GnRH secretion in mammals. In non-mammalian vertebrates, there are multiple kisspeptins (Kiss1 and Kiss2) and Kiss-R types. Recent gene knock...

journal_title：Cell and tissue research

authors： Ogawa S,Sivalingam M,Anthonysamy R,Parhar IS

更新日期：2020-02-01 00:00:00

abstract：:Osteogenic differentiation is a tightly regulated process realized by progenitor cell osteoblasts. Notch signaling pathway plays a critical role in skeletal development and bone remodeling. Controversial data exist regarding the role of Notch activation in promoting or preventing osteogenic differentiation. This study...

journal_title：Cell and tissue research

authors： Semenova D,Bogdanova M,Kostina A,Golovkin A,Kostareva A,Malashicheva A

更新日期：2020-01-01 00:00:00

abstract：:Nematocysts are characteristic organelles of the phylum Cnidaria. The free-living Platyhelminth Microstomum lineare preys on Hydra oligactis and sequesters nematocysts. All nematocyst types become phagocytosed without adherent cytoplasm by intestinal cnidophagocytes. Desmoneme and isorhiza nematocysts disappear within...

journal_title：Cell and tissue research

authors： Krohne G

更新日期：2020-01-01 00:00:00

abstract：:Autophagy (cellular self-consumption) is an adaptive stress response and an important aspect of adaption to mechanical loading. If mechanical forces are associated with autophagy regulation in periodontal ligament (PDL) fibroblasts is still unknown. The aim of this study was to analyze the influence of force magnitude...

journal_title：Cell and tissue research

authors： Memmert S,Damanaki A,Weykopf B,Rath-Deschner B,Nokhbehsaim M,Götz W,Gölz L,Till A,Deschner J,Jäger A

更新日期：2019-12-01 00:00:00

abstract：:Zebrafish (Danio rerio) is widely used as an animal model to understand the pathophysiology of cardiovascular diseases. Here, we present the adult cardiac phenotype of weak atrium, myh6-/-, which carry mutations in the zebrafish atrial myosin heavy chain. Homozygous mutants survive to adulthood and are fertile despite...

journal_title：Cell and tissue research

authors： Sarantis P,Gaitanaki C,Beis D

更新日期：2019-11-01 00:00:00

abstract：:Peeling skin syndrome is a heterogeneous group of rare disorders. Peeling skin, leukonychia, acral punctate keratoses, cheilitis and knuckle pads (PLACK syndrome, OMIM616295) is a newly described form of PSS with an autosomal recessive mode of inheritance. We report a 5.5-year-old boy with features of PLACK syndrome. ...

journal_title：Cell and tissue research

authors： Temel ŞG,Karakaş B,Şeker Ü,Turkgenç B,Zorlu Ö,Sarıcaoğlu H,Oğur Ç,Kütük Ö,Kelsell DP,Yakıcıer MC

更新日期：2019-11-01 00:00:00

abstract：:Trichoplax, a member of the phylum Placozoa, is a tiny ciliated marine animal that glides on surfaces feeding on algae and cyanobacteria. It stands out from other animals in that it lacks an internal digestive system and, instead, digests food trapped under its lower surface. Here we review recent work on the phenotyp...

journal_title：Cell and tissue research

authors： Smith CL,Mayorova TD

更新日期：2019-09-01 00:00:00

abstract：:The insect midgut epithelium represents an interface between the internal and the external environment and it is the almost unique epithelial tissue by which these arthropods acquire nutrients. This epithelium is indeed able to produce digestive enzymes and to support vectorial transport of small organic nutrients, io...

journal_title：Cell and tissue research

authors： Caccia S,Casartelli M,Tettamanti G

更新日期：2019-09-01 00:00:00

abstract：:The uptake of macromolecules and larger energy-rich particles into the cell is known as phagocytosis. Phagocytosed material is enzymatically degraded in membrane-bound vesicles of the endosome/lysosome system (intracellular digestion). Whereas most, if not all, cells of the animal body are equipped with the molecular ...

journal_title：Cell and tissue research

authors： Hartenstein V,Martinez P

更新日期：2019-09-01 00:00:00

abstract：:The comparatively simple Caenorhabditis elegans intestine fulfills many of the complex functions of the mammalian digestive tract, liver, and fat tissues, while also having roles in pathogen defense, immunity, and longevity. In this review, we describe the structure of the C. elegans gut and how it develops from the e...

journal_title：Cell and tissue research

authors： Dimov I,Maduro MF

更新日期：2019-09-01 00:00:00

abstract：:There is a current need for a therapy that can alleviate the social and economic burden that presents itself with debilitating and recurring musculoskeletal soft tissue injuries and disorders. Currently, several therapies are emerging and undergoing trials in animal models; these focus on the manipulation and administ...

journal_title：Cell and tissue research

authors： Gwyer D,Wragg NM,Wilson SL

更新日期：2019-08-01 00:00:00