Abstract：
:We used immunohistochemistry to identify cells present in pituitary allografts in the hamster. Hypophyses removed from neonatal hamsters or adenohypophyses removed from adult females were placed beneath renal capsules of hypophysectomized adult females. Serum PRL, LH, and GH concentrations were measured at two, five and eight weeks after placement of allografts. Allografts were removed after eight weeks and stained for cells containing PRL, LH, FSH, GH, or ACTH. Allografts did not release LH or GH. Those of adult adenohypophyseal tissue released significantly more PRL. The morphology of allografts of neonatal hypophyseal tissue resembled that of the adult adenohypophysis in situ. Lactotrophs, corticotrophs, somatotrophs and LH-cells were observed; very few FSH-cells were present. Allografts of adult adenohypophyseal tissue contained pituitary cells, numerous cavities, often enclosing lymphoid cells, and fibrous tissue. Atypical lactotrophs were the numerically dominant cells in these allografts; all other cells were present. The LH-cells outnumbered FSH-cells. These observations suggest that: (a) development of normal adenohypophyseal morphology can occur in an ectopic position; (b) intracellular hormones are present in cells in an ectopic site; (c) development and retention of intracellular FSH is more dependent on occupation of the normal position of the adenohypophysis than is retention of intracellular LH; and (d) release of PRL occurs from atypical cells in allografts of adult adenohypophyseal tissue.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Campbell GT,Wagoner J,Colosi P,Soares MJ,Talamantes Fdoi
10.1007/BF00215467subject
Has Abstractpub_date
1988-01-01 00:00:00pages
215-20issue
1eissn
0302-766Xissn
1432-0878journal_volume
251pub_type
杂志文章abstract：:With the use of tissue prepared by freeze-substitution and the unlabelled antibody enzyme technique, neurophysin and vasopressin were localized at the ultrastructural level in the pofterior pituitary and median eminence of the guinea pig. In the posterior pituitary neurophysin was found in the large neurosecretory gra...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221777
更新日期：1975-06-13 00:00:00
abstract：:We have examined radioautographically the protein synthetic and secretory activity of differentiating odontoblasts and ameloblasts, exposed for 9 h in vitro to various concentrations of colchicine in the presence of 3H-proline. Colchicine impairs the cytodifferentiation of the dental epithelium into ameloblasts and of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216651
更新日期：1988-06-01 00:00:00
abstract：:This investigation provides histochemical evidence for lysosomal storage of sulfated glycosaminoglycans (GAGs) in the interstitial cells of the renal cortex and in macrophage-like cells of the renal medullary zones of rats chronically treated with the drug tilorone. This compound is known to interfere with lysosomal d...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218958
更新日期：1987-12-01 00:00:00
abstract：:Two-month-old female Swiss mice that had come into estrus were injected intravenously with L-3H-fucose and killed at 5, 15, 40 min, and 4 h after injection. Pieces of the isthmus and of the ampulla of the uterine tubes were processed for light- and electron-microscopic radioautography. Incorporation of 3H-fucose was m...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220036
更新日期：1988-10-01 00:00:00
abstract：:Pituitary adenylate cyclase-activating polypeptide (PACAP) is the latest member of the vasoactive intestinal polypeptide (VIP) family of neuropeptides present in nerve fibres in many peripheral organs. Using double immunohistochemistry, with VIP as a marker for intrinsic innervation and calcitonin-gene related peptide...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900124
更新日期：2000-01-01 00:00:00
abstract：:Developmental alterations of paranodal fiber segments have not been investigated systematically in human nerve fibers at the light- and electron-microscopic level. We have therefore analyzed developmental changes in the fine structure of the paranode in 43 human sural nerves during the axonal growth period up to 5 yea...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00333704
更新日期：1993-09-01 00:00:00
abstract：:The technique of cobalt sulfide precipitation combined with Timm's sulfide-silver method for intensification of heavy metals was used to delineate the retino-hypothalamic projection of the rat. Freshly isolated rat brains were dissected and a solution of cobaltous chloride was applied to one of the cut optic nerves. S...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219728
更新日期：1976-04-28 00:00:00
abstract：:Dietary restriction (DR) retards physical growth, resulting in small body size, reduced liver weight and reduced number of hepatocytes in rats. We examined the effects of DR on proliferation and apoptosis of hepatocytes during development and explained these changes subcellularly using immunohistochemistry for bromode...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900126
更新日期：2000-03-01 00:00:00
abstract：:Ultrastructural studies of pancreatic islets have suggested that crinophagy provides a possible mechanism for intracellular degradation of insulin in the insulin-producing B-cells. In the present study, a quantitative estimation of crinophagy in mouse pancreatic islets was attempted by morphometric analysis of lysosom...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213820
更新日期：1988-04-01 00:00:00
abstract：:Intercellular junctions in the young mouse ovary were examined by electron microscopy utilizing freeze-fracture and thin-sectioning techniques. Projections from the granulosa cells adjacent to the oocyte (GI) traverse the zona pellucida and form small gap junctions on the oocyte surface. On the P-face of these cells, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216881
更新日期：1982-01-01 00:00:00
abstract：:Antithrombin (AT), which is mainly synthesized in the liver, is an acute-phase plasma protein in mammalian species. Here, we demonstrated that sheep anti-human AT antibody cross-reacted with the humoral fluids in amphioxus Branchiostoma belcheri tsingtauense as well as human serum. The concentration of AT in the humor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0088-x
更新日期：2006-03-01 00:00:00
abstract：:The fine structure, nature and fate of the components of the nucleolus were studied in young (steps 1, 2), intermediate (steps 3, 4, 5) and mature spermatids (steps 6, 7, 8) of man and monkey, by use of several cytochemical techniques (alcoholic PTA; sodium tungstate: EDTA; HAPTA; nuclease-gold complexes; NOR silver s...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305735
更新日期：1991-04-01 00:00:00
abstract：:Our immunocytochemical investigation of the magnocellular neuroendocrine system in the goldfish hypothalamus reveals enkephalin (ENK)-containing neurons interspersed among the vasotocin (VT)- and isotocin (IT)-containing neurons of the preoptic nucleus. The perikarya of the ENK, VT, and IT neurons do not show distinct...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236894
更新日期：1979-08-03 00:00:00
abstract：:The reduced-folate carrier (Rfc-1), previously also called methotrexate carrier-1 (MTX-1), was recently identified as accounting for approximately 30% of the methotrexate (Mtx) uptake into rat kidney slices. The localization of the carrier and its contribution to secretory or reabsorptive flux of the drug was therefor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1092-x
更新日期：2005-06-01 00:00:00
abstract：:The functional expression of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1) and MAdCAM-1 in the choroid plexus is indicative of a role of this structure in the communication of the immune system with the central nervous system (CNS). In order to gain further insight into the pos...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051287
更新日期：1999-05-01 00:00:00
abstract：:Changes in the organisation and composition of extracellular matrix in human endometrium during the menstrual cycle and early pregnancy have been assessed by immunofluorescence. Amongst interstitial components, type-III and type V-collagens and fibronectin are present in endometrial stroma throughout the menstrual cyc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221758
更新日期：1988-07-01 00:00:00
abstract：:The present immunocytochemical study concerns the distribution of four neuropeptides, FMRF-amide, vasotocin, leu-enkephalin and neurotensin, and of the bioamine serotonin in the plerocercoid larva of Diphyllobothrium dendriticum. Anti-FMRF-amide and vasotocin-reactivity occurs in perikarya and nerve fibres in the CNS ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222332
更新日期：1985-01-01 00:00:00
abstract：:The development of the canine proximal colon from the completion of organogenesis through 43 days after birth was studied using light microscopy, immunofluorescence and electron microscopy. During this period the tunica muscularis increased in thickness from 42+/-6 microm in animals midway through the gestation period...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00319136
更新日期：1995-10-01 00:00:00
abstract：:By use of the indirect immunofluorescence technique a small group of large somatostatin-positive neurons is described in the subependymal area of the anterior paraventricular thalamus of the male rat. Retrograde-tracing experiments suggest that they project to areas outside the blood-brain barrier. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215212
更新日期：1986-01-01 00:00:00
abstract：:This review summarizes findings concerning the unique developmental characteristics of mouse head muscles (mainly the masticatory and tongue muscles) and compares their characteristics with those of other muscles. The developmental origin of the masticatory muscles is the somitomeres, whereas the tongue and other musc...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-005-0019-x
更新日期：2005-11-01 00:00:00
abstract：:Neural stem and progenitor cells produce one of the most remarkable organs in nature, the human brain. Among neural stem cell progeny, post-mitotic neurons are likewise remarkably diverse. Single-cell transcriptomic approaches are now cataloging a long-sought-after molecular taxonomy of neuronal diversity in the brain...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2728-3
更新日期：2018-01-01 00:00:00
abstract：:Rat blood monocytes contain granules of two types, primary and secondary granules, which can be distinguished on morphological grounds. Secondary granules have a halo between the limiting membrane and the matrix; primary granules have no halo and are generally more elongate than the secondary granules. In addition, th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226665
更新日期：1977-11-30 00:00:00
abstract：:Previous neurohistological studies have been extended to include the structures contained solely or mainly within the junctional esophageal segment which may play an important role in the sphincter mechanism. The main findings were: 1) a progressive cranio-caudal thickening of the muscularis mucosae; 2) a conspicuous ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215998
更新日期：1976-05-26 00:00:00
abstract：:To further evaluate the role of autonomic ganglia in the regulation of pelvic visceral activity, the neural elements in the major pelvic ganglion of the male rat have been studied with histochemixal and electron microscopic techniques. The principal findings are that the ganglion is composed of cholinergic and adrener...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231994
更新日期：1975-05-27 00:00:00
abstract：:Corneal fibroblasts, major cellular components of the corneal stroma, are loosely arrayed between collagen lamellae. They play an important role in the metabolic and physiological homeostasis mechanisms by which the cornea is kept transparent. This paper deals with the demonstration of the gap junctions between the co...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215533
更新日期：1987-08-01 00:00:00
abstract：:The course of the Nervus connectivus (N.c.), its branches, and synaptic connections within the frontal ganglion (FG) were investigated electron microscopically after cobalt iontophoresis of the N.c. The subsequent treatment of ultrathin sections with Timm's method was found to be very suitable for identifying the smal...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00235172
更新日期：1979-01-01 00:00:00
abstract：:The effects of cytochalasin B (CB) on pancreatic structure and amylase release were studied by use of pancreatic fragments, isolated acini and isolated acinar cells. In pancreatic fragments and isolated acini CB caused the disappearance of microfilaments underlying the apical plasma membrane, loss of apical microvilli...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219848
更新日期：1977-04-29 00:00:00
abstract：:The vertebrate limb is a powerful model system for studying the cellular and molecular interactions that determine morphological pattern during embryonic development. Recent advances in our understanding of these interactions have shed new light on the molecular mechanisms of vertebrate limb development, evolution and...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410051261
更新日期：1999-04-01 00:00:00
abstract：:Zebrafish (Danio rerio) is widely used as an animal model to understand the pathophysiology of cardiovascular diseases. Here, we present the adult cardiac phenotype of weak atrium, myh6-/-, which carry mutations in the zebrafish atrial myosin heavy chain. Homozygous mutants survive to adulthood and are fertile despite...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03044-4
更新日期：2019-11-01 00:00:00
abstract：:Synaptic ribbons in photoreceptor cells of the goldfish pineal organ undergo significant daily changes in their length, distance from the plasma membrane, and number per unit area of pineal end-vesicle. The rhythms persist in fish exposed to constant darkness. Constant light abolishes the rhythms in length and distanc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233525
更新日期：1981-01-01 00:00:00
