Morphological changes during ontogeny of the canine proximal colon.


:The development of the canine proximal colon from the completion of organogenesis through 43 days after birth was studied using light microscopy, immunofluorescence and electron microscopy. During this period the tunica muscularis increased in thickness from 42+/-6 microm in animals midway through the gestation period to 317+/-29 microm in animals 25-30 days old. This increase in thickness resulted from an increase in the number and size of smooth muscle cells in the circular and longitudinal muscle layers. The cross-sectional thickness of the circular muscle layer increased from 10+/-2 smooth muscle cells midway through the gestation period to 92+/-7 cells in animals 25-30 days old. The longitudinal layer increased in thickness from 1.5+/-1 cells in animals midway through the gestation period to 44+/-2 cells in animals 25-30 days old. Smooth muscle cells from both layers also increased in diameter and length. Ultrastructural and immunohistochemical studies suggested that many of the smooth muscle cells were undergoing development throughout the fetal period. Midway through the gestation period, the circular layer was positive for desmin-like immunoreactivity (D-LI), while both the circular and longitudinal layers were positive for vimentin-like immunoreactivity (V-LI). By birth, V-LI was suppressed in the circular and longitudinal layers, and both layers expressed D-LI. The enteric nervous system was already established midway through the gestation period, and submucosal and myenteric ganglia could be identified, although the chemical coding and mature morphology of neurons were incomplete. NADPH-diaphorase-positive neurons, indicating the expression of nitric oxide synthase, developed by the time of birth. Interstitial cells of Cajal (IC) could not clearly be identified midway through gestation, however, potential precursors to ICs were observed. Several classes of ICs were identifiable at birth.


Cell Tissue Res


Cell and tissue research


Ward SM,Torihashi S




Has Abstract


1995-10-01 00:00:00












  • Calbindin immunoreactivity in the enteric nervous system of larval and adult zebrafish (Danio rerio).

    abstract::Calbindin is a calcium-binding protein, commonly found in certain subpopulations of the enteric nervous system in mammals. Recently, calbindin-immunoreactive enteric neurons have also been demonstrated in shorthorn sculpin (Myoxocephalus scorpius). In the present study, calbindin immunoreactivity has been investigated...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Olsson C

    更新日期:2011-04-01 00:00:00

  • A pair of descending neurons with dendrites in the optic lobes projecting directly to thoracic ganglia of dipterous insects.

    abstract::The lobula descending neuron (LDN) of dipterous insects is a unique nerve cell (one on each side of the brain) that projects directly from the lobula complex of the optic lobes to neuropil in thoracic ganglia. In the supraoesophageal ganglia the LDN has two prominent groups of branches of which at least one is dendrit...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Nässel DR,Strausfeld NJ

    更新日期:1982-01-01 00:00:00

  • Distribution of the Aplysia cardioexcitatory peptide, NdWFamide, in the central and peripheral nervous systems of Aplysia.

    abstract::NdWFamide is an Aplysia cardioexcitatory tri-peptide containing D-tryptophan. To investigate the roles of this peptide, we examined the immunohistochemical distribution of NdWFamide-positive neurons in Aplysia tissues. All the ganglia of the central nervous system (CNS) contained NdWFamide-positive neurons. In particu...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Morishita F,Nakanishi Y,Sasaki K,Kanemaru K,Furukawa Y,Matsushima O

    更新日期:2003-04-01 00:00:00

  • Ultracytochemical evidence for a proton-pump adenosine triphosphatase in chick osteoclasts.

    abstract::The distribution of Mg++-ATPase in osteoclasts along the endosteal surface of the chick tibia was investigated by neutral and alkaline pH cytochemical methods at the electron-microscopic level. Reaction product was observed in mitochondria, cytoplasmic vesicles, and ruffled-border membrane. Levamisole, ouabain, and va...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Akisaka T,Gay CV

    更新日期:1986-01-01 00:00:00

  • Neurotrophin receptors and enteric neuronal development during metamorphosis in the amphibian Xenopus laevis.

    abstract::During metamorphosis, the frog intestine goes through a dramatic shortening with extensive apoptosis and regeneration in the epithelial layer and connective tissue. Our aim was to study changes in the enteric nervous system represented by one inhibitory (vasoactive intestinal polypeptide; VIP) and one excitatory (subs...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Sundqvist M,Holmgren S

    更新日期:2004-04-01 00:00:00

  • The ultrastructure of the mid-gut cells of Nasonia vitripennis (Walker) (Hymenoptera, Pteromalidae).

    abstract::The ultrastructure of the mid-gut cells of female Nasonia vitripennis is described. The mid-gut consists of a uniform, single-cell epithelium. The cells of different gut regions were analysed using morphometric techniques in order to determine any differences in the components. The structure of the cells is described ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Davies I,King PE

    更新日期:1977-02-09 00:00:00

  • Adult insect mushroom body neurons in primary culture: cell morphology and characterization of potassium channels.

    abstract::The dissociation and maintenance in culture of cells derived from the mushroom bodies of adult crickets (Acheta domesticus) are described. This primary culture was developed in order to investigate maturation and differentiation of mushroom-body cells including Kenyon cells, the major intrinsic interneurons of mushroo...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Cayre M,Buckingham SD,Strambi A,Strambi C,Sattelle DB

    更新日期:1998-03-01 00:00:00

  • Catecholamine-containing pancreatic islet cells of the domestic fowl. Light, fluorescence and electron microscopy, and immunohistochemistry.

    abstract::In an attempt to identify pancreatic islet cells emitting formaldehyde-induced fluorescence (FIF), the pancreatic islets of the domestic fowl were studied by combined fluorescence, ultrastructural, silver-impregnation and immunohistochemical methods in the same section or in consecutive semi-thin and ultra-thin sectio...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Watanabe T,Chikazawa H,Yamada J

    更新日期:1984-01-01 00:00:00

  • Distribution of subgroups of noradrenaline neurons in the coeliac ganglion of the guinea-pig.

    abstract::The distributions within the coeliac ganglion of different chemically coded subgroups of noradrenaline neurons, and the relationships between these neurons and nerve fibres projecting to the ganglion from the intestine, have been assessed quantitatively by use of an immunohistochemical double-staining method. Noradren...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Macrae IM,Furness JB,Costa M

    更新日期:1986-01-01 00:00:00

  • Distribution of neurons with high-affinity uptake sites for GABA in the myenteric plexus of the guniea-pig, rat and chicken.

    abstract::The occurrence of neurons possessing high-affinity uptake sites for GABA was studied in the myenteric plexus of the guinea-pig ileum, caecum, and proximal and distal colon, the rat proximal colon, and the chicken gizzard with the use of 3H-GABA and autoradiography. Experiments were carried out on plexuses that had bee...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Saffrey MJ,Marcus N,Jessen KR,Burnstock G

    更新日期:1983-01-01 00:00:00

  • Components and connections of the circadian timing system in mammals.

    abstract::The circadian timing system is a neural network consisting of the hypothalamic suprachiasmatic nucleus, aided by the retina, other hypothalamic nuclei, autonomic regions of the spinal cord, sympathetic ganglia and the pineal gland. Extensive studies conducted over the last two decades have unravelled the principal ite...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Reuss S

    更新日期:1996-09-01 00:00:00

  • An ultracytochemical investigation of ouabain-sensitive p-nitrophenylphosphatase in chick osteoclasts.

    abstract::Cytochemical methods for the demonstration of p-nitrophenylphosphatase (p-NPPase) at the electron-microscopic level were applied to avian osteoclasts to elucidate some of the functional differences among ruffled border, other membrane systems, and cellular organelles. The localization of p-NPPase activity occurred in ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Akisaka T,Gaỳ CV

    更新日期:1986-01-01 00:00:00

  • Two-color double-labeling in situ hybridization of whole-mount Hydra using RNA probes for five different Hydra neuropeptide preprohormones: evidence for colocalization.

    abstract::The freshwater polyp Hydra magnipapillata has a primitive nervous system that produces at least three distinct classes of neuropeptides: various peptides having the C-terminal sequence Arg-Phe-NH2 (the Hydra-RFamide family), Leu-Trp-NH2 (the Hydra-LWamide family), and a single peptide having the C-terminal sequence Ly...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Hansen GN,Williamson M,Grimmelikhuijzen CJ

    更新日期:2000-08-01 00:00:00

  • Chiton integument: ultrastructure of the sensory hairs of Mopalia muscosa (Mollusca: Polyplacophora).

    abstract::The dorsal integument of the girdle of the chiton Mopalia muscosa is covered by a chitinous cuticle about 0.1 mm in thickness. Within the cuticle are fusiform spicules composed of a central mass of pigment granules surrounded by a layer of calcium carbonate crystals. Tapered, curved chitinous hairs with a groove on th...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Leise EM,Cloney RA

    更新日期:1982-01-01 00:00:00

  • Quantitation of pulmonary neuroepithelial bodies in pre- and postnatal rabbits.

    abstract::The size, density and total number of neuroepithelial bodies (NEB) in the lungs of late fetal, neonatal, and mature rabbits were determined using fluorescence microscopy. In this study lungs from 27-, 29-, 30-, and 31-day fetuses; neonates of ages 2, 7, and 30 days; and 4- and 7(+)-month-old rabbits, were used. The to...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Redick ML,Hung KS

    更新日期:1984-01-01 00:00:00

  • TrkA and TrkC neurotrophin receptor-like proteins in the lizard gut.

    abstract::The tyrosine kinase proteins (Trk), encoded by the trk family of proto-oncogenes, mediate, in mammals, the action of neurotrophins, a family of growth factors acting on the development and maintenance of the nervous system. Neurotrophins and their specific receptors, TrkA, TrkB and TrkC, seem to be phylogenetically we...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Lucini C,de Girolamo P,Lamanna C,Botte V,Vega JA,Castaldo L

    更新日期:2001-03-01 00:00:00

  • Colocalization of oxidized low-density lipoprotein, caspase-3, cyclooxygenase-2, and macrophage migration inhibitory factor in arteriosclerotic human carotid arteries.

    abstract::Apoptotic and inflammatory processes occur in human arteriosclerotic lesions. We examined the hypothesis whether both processes are possibly associated by studying the colocalization of corresponding markers. In 11 human arteriosclerotic carotid arteries, proapoptotic markers (CPP32 (caspase-3), poly(ADP-ribose) polym...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Schlittenhardt D,Schmiedt W,Bonaterra GA,Metz J,Kinscherf R

    更新日期:2005-12-01 00:00:00

  • Neuronal background of activation of estivated snails, with special attention to the monoaminergic system: a biochemical, physiological, and neuroanatomical study.

    abstract::Osmotic stimulation activates both estivated and inactivated specimens of Helix pomatia and increases their central arousal. High-pressure liquid chromatography has shown that, during activation, the level of both serotonin and dopamine decreases in the central nervous system (CNS) but increases in the foot and heart,...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Hernádi L,Vehovszky A,Gyori J,Hiripi L

    更新日期:2008-02-01 00:00:00

  • Studies on the fine structure of invertebrate blood vessels. II. The valves of the lateral sinus of the leech, Hirudo medicinalis L.

    abstract::The position, structure and function of the valves within the lateral sinus of the medical leech, Hirudo medicinalis, are described on the basis of vital, light- and electron microscopy. In this species the valvular apparatus consists of multiple elongated fir cone-shaped fibrous villi surrounding the orifices of the ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Hammersen F,Staudte HW,Möhring E

    更新日期:1976-09-20 00:00:00

  • Responses of pineal photoreceptors in the brook and rainbow trout.

    abstract::Electron microscopy of the pineal receptor cells in light- and dark-adapted brook trout, Salvelinus fontinalis and the rainbow trout, Salmo gairdneri, revealed no significant differences in the tubular and filamentous elements of the inner segment, neck and supranuclear regions. However, changes in synaptic relations ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Omura Y,Ali MA

    更新日期:1980-01-01 00:00:00

  • Cardiac dysfunction in transgenic mouse fetuses overexpressing shortened type XIII collagen.

    abstract::Overexpression of type XIII collagen molecules with an 83-amino-acid residue in-frame deletion of part of the ectodomain leads to fetal lethality in Col13a1COL2del transgenic mice. We characterize here the functional disturbances in the cardiovascular system of mouse fetuses overexpressing mutant type XIII collagen. D...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Tahkola J,Räsänen J,Sund M,Mäkikallio K,Autio-Harmainen H,Pihlajaniemi T

    更新日期:2008-07-01 00:00:00

  • Peritrophic matrix of Phlebotomus duboscqi and its kinetics during Leishmania major development.

    abstract::Light microscopy of native preparations, histology, and electron microscopy have revealed that Phlebotomus duboscqi belongs to a class of sand fly species with prompt development of the peritrophic matrix (PM). Secretion of electron-lucent fibrils, presumably chitin, starts immediately after the ingestion of a blood m...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Sádlová J,Volf P

    更新日期:2009-08-01 00:00:00

  • Concanavalin A-binding glycoproteins in the subcommissural and the pineal organ of the sheep (Ovis aries). A fluorescence-microscopic and electrophoretic study.

    abstract::Glycoproteins rich in mannosyl or glucosyl residues were analyzed in the subcommissural organ (SCO) and the pineal organ of the sheep (Ovis aries). By use of concanavalin A labelled with fluorescein isothiocyanate, fluorescent material was found both in ependymal and hypendymal cells of the SCO. In the pineal organ, e...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Meiniel R,Molat JL,Meiniel A

    更新日期:1986-01-01 00:00:00

  • Fine structure of the ependyma and intercellular junctions in the area postrema of the rat.

    abstract::Ependymal cells and their junctional complexes in the area postrema of the rat were studied in detail by tracer experiments using horseradish peroxidase (HRP) and colloidal lanthanum and by freeze-etch techniques, in addition to routine electron microscopy. The ependyma of the area postrema is characterized as flatten...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Gotow T,Hashimoto PH

    更新日期:1979-09-03 00:00:00

  • The influence of androgen administration on the structure and function of the brain-pituitary-gonad axis of sexually immature platyfish, Xiphophorus maculatus.

    abstract::This report demonstrates that the administration of testosterone (T) or 11-ketotestosterone (11-KT) to sexually immature (8 wks old) male platyfish (Xiphophorus maculatus) of early- and late-maturing genotypes affects the synthesis and/or release of luteinizing hormone-releasing hormone (LHRH), as assessed by immunocy...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Schreibman MP,Margolis-Nunno H,Halpern-Sebold LR,Goos HJ,Perlman PW

    更新日期:1986-01-01 00:00:00

  • Ecdysteroid binding sites localized by autoradiography in the central nervous system of precommitment fifth-stadium Manduca sexta larvae.

    abstract::Brains and subesophageal ganglia from day 3.5 fifth stadium larvae of Manduca sexta were incubated in vitro with 4 nM tritiated ponasterone A, a 20-hydroxyecdysone analog, to determine whether uptake and specific binding of ecdysteroids occur at a cellular level. These tissues, which were taken just prior to the commi...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Bidmon HJ,Stumpf WE,Granger NA

    更新日期:1991-01-01 00:00:00

  • Nuage morphogenesis becomes more complex: two translocation pathways and two forms of nuage coexist in Drosophila germline syncytia.

    abstract::We have developed a simple and reliable method of preserving antigen immunoreactivity with concomitant excellent retention of the cell ultrastructure. Using this method, we have been able to follow the origin and developmental stages of nuage accumulations within the nurse cell/oocyte syncytium in the ovary of the fru...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Jaglarz MK,Kloc M,Jankowska W,Szymanska B,Bilinski SM

    更新日期:2011-04-01 00:00:00

  • Ultrastructure of the main excretory duct epithelium of the female mouse submandibular gland with special reference to sexual dimorphism.

    abstract::The fine structure of the main excretory duct epithelium (MEDE) of female mouse submandibular gland was investigated by scanning and transmission electron microscopy and the results compared with the previously established structure of male mouse MEDE. A comparative analysis of the subepithelial capillaries of both se...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Sato A,Goto F,Miyoshi S

    更新日期:1994-09-01 00:00:00

  • Redifferentiation of dedifferentiated human chondrocytes in high-density cultures.

    abstract::High-density cultures are widely used as an in vitro model for studies of embryonic cartilage formation. In the present study we investigated the suitability of high-density cultures for the redifferentiation of dedifferentiated chondrocytes. When primary human chondrocytes were cultured in alginate beads, some cells ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Schulze-Tanzil G,de Souza P,Villegas Castrejon H,John T,Merker HJ,Scheid A,Shakibaei M

    更新日期:2002-06-01 00:00:00

  • Projection of ventrolateral medullary (A1) catecholamine neurons toward nucleus tractus solitarii.

    abstract::The distribution and interconnections of brainstem catecholamine cell groups thought to be important in cardiovascular control were studied using histochemical and ultrastructural techniques in the rabbit. Lesions and microinjections of horseradish peroxidase (HRP) were made in the nucleus tractus solitarii in the dor...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Blessing WW,Furness JB,Costa M,West MJ,Chalmers JP

    更新日期:1981-01-01 00:00:00