Morphological changes during ontogeny of the canine proximal colon.


:The development of the canine proximal colon from the completion of organogenesis through 43 days after birth was studied using light microscopy, immunofluorescence and electron microscopy. During this period the tunica muscularis increased in thickness from 42+/-6 microm in animals midway through the gestation period to 317+/-29 microm in animals 25-30 days old. This increase in thickness resulted from an increase in the number and size of smooth muscle cells in the circular and longitudinal muscle layers. The cross-sectional thickness of the circular muscle layer increased from 10+/-2 smooth muscle cells midway through the gestation period to 92+/-7 cells in animals 25-30 days old. The longitudinal layer increased in thickness from 1.5+/-1 cells in animals midway through the gestation period to 44+/-2 cells in animals 25-30 days old. Smooth muscle cells from both layers also increased in diameter and length. Ultrastructural and immunohistochemical studies suggested that many of the smooth muscle cells were undergoing development throughout the fetal period. Midway through the gestation period, the circular layer was positive for desmin-like immunoreactivity (D-LI), while both the circular and longitudinal layers were positive for vimentin-like immunoreactivity (V-LI). By birth, V-LI was suppressed in the circular and longitudinal layers, and both layers expressed D-LI. The enteric nervous system was already established midway through the gestation period, and submucosal and myenteric ganglia could be identified, although the chemical coding and mature morphology of neurons were incomplete. NADPH-diaphorase-positive neurons, indicating the expression of nitric oxide synthase, developed by the time of birth. Interstitial cells of Cajal (IC) could not clearly be identified midway through gestation, however, potential precursors to ICs were observed. Several classes of ICs were identifiable at birth.


Cell Tissue Res


Cell and tissue research


Ward SM,Torihashi S




Has Abstract


1995-10-01 00:00:00












  • Histochemical and ultrastructural study of the nervous elements in the pineal organ of the eel, Anuilla anguilla.

    abstract::The pineal organ of the eel, Anguilla anguilla was studied light-and electron-microscopically. The tissue consists predominantly of glia-like supporting cells and photoreceptor-like sensory cells, which establish synaptic contacts with pineal nerve cells. Histochemically, a positive acetylcholinesterase (AchE) reactio...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Matsuura T,Herwig HJ

    更新日期:1981-01-01 00:00:00

  • A critical reevaluation of the structure of the rat uriniferous tubule as revealed by scanning electron microscopy.

    abstract::The fine structure of luminal surface of clearly identified portions of uriniferous tubules has been studied by scanning electron microscopy to elucidate some controversies concerning the topography of certain surface formations. The results show a characteristic pattern of the luminal surface in the region of Henle's...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Pfaller W,Klima J

    更新日期:1976-02-06 00:00:00

  • The visual system of the guitar fish (Rhinobatos productus).

    abstract::The retinal projections in adult and juvenile guitar fish (Rhinobatos productus) were determined with the aid of the Nauta-Fink-Heimer techniques. The visual system was found to be more extensive and more differentiated than in any other elasmobranch studied to date. Massive projections exist to the dorsal and ventral...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Ebbesson SO,Meyer DL

    更新日期:1980-01-01 00:00:00

  • Treatment of cancer stem cells from human colon adenocarcinoma cell line HT-29 with resveratrol and sulindac induced mesenchymal-endothelial transition rate.

    abstract::In the current experiment, the combined regime of resveratrol and a Wnt-3a inhibitor, sulindac, were examined on the angiogenic potential of cancer stem cells from human colon adenocarcinoma cell line HT-29 during 7 days. Cancer stem cells were enriched via a magnetic-activated cell sorter technique and cultured in en...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Pouyafar A,Rezabakhsh A,Rahbarghazi R,Heydarabad MZ,Shokrollahi E,Sokullu E,Khaksar M,Nourazarian A,Avci ÇB

    更新日期:2019-06-01 00:00:00

  • Insect UV-, and green-photoreceptor membranes studied by the freeze-fracture technique.

    abstract::The membranes of the microvilli of UV- and green-photoreceptors of the ant Myrmecia gulosa have been studied with the freeze-fracture technique. Both inner fracture faces, the cytoplasmic P-face and the extracellular E-face, are covered by globular particles. The P-face particles appear to be randomly distributed, occ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Nickel E,Menzel R

    更新日期:1976-12-10 00:00:00

  • Adaptation of the black tiger shrimp, Penaeus monodon, to different salinities through an excretory function of the antennal gland.

    abstract::Black tiger shrimps (Penaeus monodon) are able to survive and can be reared under various salinities, possibly by the cellular adaptation of their excretory system, particularly the antennal gland, which is known to regulate body fluid in crustaceans. We have investigated the morphological and biochemical alterations ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Buranajitpirom D,Asuvapongpatana S,Weerachatyanukul W,Wongprasert K,Namwong W,Poltana P,Withyachumnarnkul B

    更新日期:2010-06-01 00:00:00

  • The glucose transport facilitator GLUT8 is predominantly associated with the acrosomal region of mature spermatozoa.

    abstract::The glucose transporter 8 (GLUT8) is a recently identified member of the family of sugar transport facilitators. In human tissues GLUT8 is predominantly expressed in testis in a gonadotropin-dependent manner. It is shown here that the onset of mRNA synthesis of GLUT8 during the maturation of mouse testis coincides wit...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Schürmann A,Axer H,Scheepers A,Doege H,Joost HG

    更新日期:2002-02-01 00:00:00

  • A quantitative ultrastructural analysis of changes in hamster cheek-pouch epithelium treated with vitamin A.

    abstract::The ultrastructural changes induced by the topical application of retinol acetate on hamster cheek pouch epithelium were evaluated using stereological analysis. Electron micrographs were prepared of the basal and superficial regions of the nucleated cell layer of the epithelium obtained from 3 treated and 3 control an...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Hill MW,Harris RR,Carron CP

    更新日期:1982-01-01 00:00:00

  • Calbindin immunoreactivity in the enteric nervous system of larval and adult zebrafish (Danio rerio).

    abstract::Calbindin is a calcium-binding protein, commonly found in certain subpopulations of the enteric nervous system in mammals. Recently, calbindin-immunoreactive enteric neurons have also been demonstrated in shorthorn sculpin (Myoxocephalus scorpius). In the present study, calbindin immunoreactivity has been investigated...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Olsson C

    更新日期:2011-04-01 00:00:00

  • Specialized contacts between sarcolemma and sarcoplasmic reticulum at the ends of muscle fibers in the diaphragm of the rat.

    abstract::An electron-microscopic study of the myotendinous portion of the diaphragm in the Wistar rat has shown that at the ends of muscle fibers, longitudinally oriented invaginations and peripheral furrows of the sarcolemma establish specialized contacts with individual sacs of the sarcoplasmic reticulum. The construction of...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Andreev DP,Wassilev WA

    更新日期:1986-01-01 00:00:00

  • A new type of gap junction in the phylum Brachiopoda.

    abstract::Gap junctions in the phylum Brachiopoda are shown to be of the P type as has been previously reported in invertebrates only in molluscs and possibly bryozoans. However, the mollusc gap junctions appear identical to vertebrae gap junctions in the fracture face on which particles remain, in particle spacing and in parti...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Flower NE,Green CR

    更新日期:1982-01-01 00:00:00

  • FGF2 and dexamethasone increase the production of hyaluronan in two-dimensional culture of elastic cartilage-derived cells: in vitro analyses and in vivo cartilage formation.

    abstract::Elastic cartilage-derived cells cultured two-dimensionally with FGF2 and corticosteroid produce gel-type masses that become mature cartilage when injected into a subcutaneous pocket. This unique method has previously been clinically applied for treatments of nasal augmentation. However, the components of the gel-type ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Yokoyama A,Muneta T,Nimura A,Koga H,Mochizuki T,Hata Y,Sekiya I

    更新日期:2007-09-01 00:00:00

  • Fibronectin and its relation to the basal lamina and to the cell surface in the chicken blastoderm.

    abstract::The ultrastructural distribution of fibronectin immunoreactivity was investigated in the chicken embryo during late gastrulation. Sites of binding of anti-fibronectin antibodies were ascribed to the basal lamina and associated structures, and to the cell surface. The fibronectin-rich basal lamina was resolved into a l...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Harrisson F,Vanroelen C,Vakaet L

    更新日期:1985-01-01 00:00:00

  • Studies of isolated and enriched rat antral mucosa gastrin cells.

    abstract::A technique has been developed to obtain viable, isolated and enriched populations of gastrin cells (G-cells) from the rat stomach. Restricted tissue samples from a small area of the pyloric antrum known to be particularly rich in G-cells, were sequentially digested with pronase followed by mechanical agitation, to re...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Forssmann WG,Lichtenberger LM,Helmstaedter V,Ito S

    更新日期:1979-08-01 00:00:00

  • The morphology and cell culture of the striated musculature of the rat azygos vein.

    abstract::The azygos vein of the rat can be divided into three regions: The proximal cardiac region, where the wall is composed of two and sometimes three layers of cardiac muscle and a thin discontinuous layer of smooth muscle cells. Vascular casts of this region demonstrate layers of capillaries closely following the orientat...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Cullinan V,Campbell JH,Mosse PR,Campbell GR

    更新日期:1986-01-01 00:00:00

  • Quantitative analysis of rod-cored vesicles and dense granules of large granular lymphocytes in the liver, spleen, and peripheral blood of rats.

    abstract::Large granular lymphocytes (LGL) comprise a natural defense system in the liver and exert an inhibitory effect on tumor cell metastasis. In order to demonstrate the maturation of LGL in the liver from the morphological aspect, we evaluated electron-microscopically the frequency of 0.2 micron vesicles (rod-cored and "e...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Kaneda K,Pilaro AM,Sayers TJ,Nagashima K,Gonda MA,Ortaldo JR,Wiltrout RH

    更新日期:1994-04-01 00:00:00

  • Human chorionic-plate-derived mesenchymal stem cells and Wharton's jelly-derived mesenchymal stem cells: a comparative analysis of their potential as placenta-derived stem cells.

    abstract::Placenta-derived stem cells (PDSCs) have gained interest as an alternative source of stem cells for regenerative medicine because of their potential for self-renewal and differentiation and their immunomodulatory properties. Although many studies have characterized various PDSCs biologically, the properties of the sel...

    journal_title:Cell and tissue research

    pub_type: 临床试验,杂志文章


    authors: Kim MJ,Shin KS,Jeon JH,Lee DR,Shim SH,Kim JK,Cha DH,Yoon TK,Kim GJ

    更新日期:2011-10-01 00:00:00

  • Islet amyloid polypeptide (IAPP) in the gastrointestinal tract and pancreas of man and rat.

    abstract::An immunohistochemical study for islet amyloid polypeptide (IAPP) was made on the gastrointestinal (GI) tract and pancreas of man and rat, using antisera raised against a synthetic peptide of C-terminal human IAPP (24-37) and a synthetic peptide of rat IAPP (18-37). A large number of IAPP-immunoreactive cells were fou...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Toshimori H,Narita R,Nakazato M,Asai J,Mitsukawa T,Kangawa K,Matsuo H,Matsukura S

    更新日期:1990-12-01 00:00:00

  • To serve and to protect: the role of decidual innate immune cells on human pregnancy.

    abstract::The maternal-fetal interface undergoes dynamic changes that promote successful development of the embryo/fetal allograft during pregnancy. This immune privilege of the conceptus is mediated through local and systemic cellular responses. In species in which endometrial decidualization accompanies pregnancy, unique immu...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Zhang J,Dunk C,Croy AB,Lye SJ

    更新日期:2016-01-01 00:00:00

  • Correction to: Immunolocalization and changes of 17beta-estradiol during ovarian development of Chinese mitten crab Eriocheir sinensis.

    abstract::The published online version contains mistake in Title and in Acknowledgement section. Please find below for the needed corrections. ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,已发布勘误


    authors: Pan J,Liu M,Chen T,Cheng Y,Wu X

    更新日期:2018-10-01 00:00:00

  • The pituitary of Aphanius dispar (Rüppell) from hypersaline marshes and freshwater. II. Ultrastructure of the rostral pars distalis.

    abstract::An ultrastructural study of the rostral pars distalis of the pituitary of Aphanius dispar specimens taken from freshwater or hypersaline marshes revealed significant structural differences which indicate higher activity of the prolactin cells in the hypotonic medium. Prolactin cells from freshwater specimens had large...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Abraham M,Dinari-Lavie V,Lotan R

    更新日期:1977-04-20 00:00:00

  • Ultrastructure of the heart muscle cells of the cuttlefish Rossia macrosoma (Delle Chiaje) (Mollusca: Cephalopoda).

    abstract::The muscle cells of the ventricle, the branchial heart and the branchial heart appendages of Rossia macrosoma (Delle Chiaje) are studied. The ventricle myocardium has three muscle layers, while the other two organs exhibited a loose arrangement of muscle cells. The muscle cells of the ventricle, the branchial heart an...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Jensen H,Tjonneland A

    更新日期:1977-12-13 00:00:00

  • Immunohistochemical localization of serotonin in intrapulmonary neuro-epithelial bodies.

    abstract::A recently developed immunohistochemical technique for serotonin (Steinbusch et al. 1978) was used in the present investigation to study the occurrence of this indoleamine in the granulated epithelial cells of neuro-epithelial bodies (NEB). Lungs from neonatal rabbits and pigs exhibit immunoreactive cell groups identi...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Lauweryns JM,de Bock V,Verhofstad AA,Steinbusch HW

    更新日期:1982-01-01 00:00:00

  • Morphological and functional changes in the tight junctions of the bile canaliculi induced by bile duct ligation.

    abstract::Thin sections after bile duct ligation showed that the depth of tight junctions appeared to increase and that the distance between individual punctate contacts appeared to become irregular and wider than in controls. The freeze fracture replicas clearly demonstrated these changes in the tight junction morphology. Chan...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Koga A,Todo S

    更新日期:1978-12-28 00:00:00

  • Scanning electron microscopy of macrophages in the tail musculature of the metamorphosing anuran tadpole, Rana japonica.

    abstract::Scanning electron microscopy was used to investigate the morphological changes of the tail musculature of the metamorphosing anuran tadpole, attention being focused on phagocytosis by macrophages. Muscle fibers were stained en bloc with silver and freeze-fractured during dehydration, or torn after drying. Samples were...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Watanabe K,Horiguchi T,Sasaki F

    更新日期:1985-01-01 00:00:00

  • Phagocytosis in cellular defense and nutrition: a food-centered approach to the evolution of macrophages.

    abstract::The uptake of macromolecules and larger energy-rich particles into the cell is known as phagocytosis. Phagocytosed material is enzymatically degraded in membrane-bound vesicles of the endosome/lysosome system (intracellular digestion). Whereas most, if not all, cells of the animal body are equipped with the molecular ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Hartenstein V,Martinez P

    更新日期:2019-09-01 00:00:00

  • Lamina propria of intestinal mucosa as a typical reticular tissue. A scanning electron-microscopic study of the rat jejunum.

    abstract::The three-dimensional architecture of the lamina propria in the jejunal mucosa of the rat was studied by scanning electron microscopy. The lamina propria is a typical reticular tissue with fine nets of reticular fibers and free and fixed cells lying among them. However, the lamina propria in the core of villi displaye...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Takahashi-Iwanaga H,Fujita T

    更新日期:1985-01-01 00:00:00

  • Production of an endothelial cell migratory signal in rat endometrium during early pregnancy.

    abstract::Rat endometrial explants were cultured in a three-dimensional collagen/endothelial cell matrix to measure angiogenic activity, as represented by migration of vascular endothelial cells towards the explants. Minimal endothelial cell migratory activity was observed with endometrial explants taken during the four-day oes...

    journal_title:Cell and tissue research

    pub_type: 历史文章,杂志文章


    authors: Abberton KM,Rogers PA

    更新日期:1995-01-01 00:00:00

  • VEGF inhibition: insights from preclinical and clinical studies.

    abstract::Angiogenesis, the growth of new blood vessels, is required for a variety of normal proliferative processes. Furthermore, angiogenesis is well established as also playing an important role in neoplastic growth and metastasis. Numerous regulators of angiogenesis have been identified and characterized over the last few d...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Crawford Y,Ferrara N

    更新日期:2009-01-01 00:00:00

  • Cytoprotective role of vitamin E in porcine adipose-tissue-derived mesenchymal stem cells against hydrogen-peroxide-induced oxidative stress.

    abstract::Survival of mesenchymal stem cells (MSCs) against oxidative stress and inflammation is vital for effective stem cell therapy. The reactive oxygen species (ROS) result in apoptosis and release of inflammatory mediators. Adipose-derived stem cells (ASCs) have shown promise for stem cell therapy owing to their anti-infla...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Bhatti FUR,Kim SJ,Yi AK,Hasty KA,Cho H

    更新日期:2018-10-01 00:00:00