Single-cell analysis of diversity in human stem cell-derived neurons.

abstract：:Spermatozoa from the cauda epididymidis of gossypol-treated rats exhibit distinctive departures from the morphology of spermatozoa from control rats: wrinkled and disorganized cell membrane in the head and tail regions, cell membrane missing from segments of the tail midpiece and principal piece regions, malformed hea...

journal_title：Cell and tissue research

authors： Bozek SA,Jensen DR,Tone JN

更新日期：1981-01-01 00:00:00

abstract：:Early in postnatal life, the first wave of spermatogenesis is accompanied by an initial wave of germ cell apoptosis. This may reflect an adjustment in the number of germ cells that can be adequately maintained by Sertoli cells. Two major pathways (intrinsic and extrinsic) are involved in the process of caspase activat...

journal_title：Cell and tissue research

authors： Moreno RD,Lizama C,Urzúa N,Vergara SP,Reyes JG

更新日期：2006-09-01 00:00:00

abstract：:Antibodies raised against the cystic fibrosis transmembrane regulator protein (CFTR) were used to localize CFTR in intestinal tissues of piglets and mice. Positive staining for CFTR was detected in goblet cells of both species. A second population of epithelial cells of unknown phenotype was also labeled by anti-CFTR ...

journal_title：Cell and tissue research

authors： Hayden UL,Carey HV

更新日期：1996-02-01 00:00:00

abstract：:The ontogeny of two gonadotropin-releasing-hormone (GnRH) systems, salmon GnRH (sGnRH) and chicken GnRH-II (cGnRH-II), was investigated in zebrafish (Danio rerio). In situ hybridization (ISH) first detected sGnRH mRNA-expressing cells at 1 day post-fertilization (pf) anterior to the developing olfactory organs. Subseq...

journal_title：Cell and tissue research

authors： Palevitch O,Kight K,Abraham E,Wray S,Zohar Y,Gothilf Y

更新日期：2007-02-01 00:00:00

abstract：:Research in mammals has established the existence of a neuronal network that lies within the hypothalamus and that regulates energy homeostasis. However, it is unknown whether this system has been evolutionarily conserved. The objective of the present study was therefore to examine the influence of the agouti-related ...

journal_title：Cell and tissue research

authors： Phillips-Singh D,Li Q,Takeuchi S,Ohkubo T,Sharp PJ,Boswell T

更新日期：2003-08-01 00:00:00

abstract：:The projections of ocellar fibres within the brain and thorax of the honey bee, Apis mellifera, were established using a modified cobalt sulphide technique, supplemented by serial sectioning of the brain for the light microscope. The results are: 5 large fibres in each lateral nerve and 12 in the median nerve have wid...

journal_title：Cell and tissue research

authors： Pan KC,Goodman LJ

更新日期：1977-01-24 00:00:00

abstract：:In Nassarius reticulatus the nuclei and nucleoli undergo important morphological changes from the zygote to the 16-cell stage. In the zygote and in the trefoil (2-cell) and 4-cell stage, several agranular, fibrillar nucleolus-like bodies 1 mum diameter are present in the interphase nucleus. Granular nucleoli first app...

journal_title：Cell and tissue research

authors： Schmekel L,Fioroni P

更新日期：1976-05-13 00:00:00

abstract：:The ultrastructure of crystalline beta granules of the islets of Langerhans in the alligator has been investigated. From optical diffraction analysis and serial sectioning, the existence of four distinct types of crystalline inclusions was established in ultrathin sections. The first type is the most frequent and is i...

journal_title：Cell and tissue research

authors： Raska I,Komrska J,Titlbach M,Rieder M

更新日期：1978-03-13 00:00:00

abstract：:An improved technique for fluorescent labelling of heavy meromyosin has made it possible to detect on a light microscopic level the cellular sites of actin localization. Rabbit heavy meromyosin (HMM) was labelled with fluorescein isothiocyanate so that the actin binding site was protected during the reaction. The spec...

journal_title：Cell and tissue research

authors： Sanger JW

更新日期：1975-08-27 00:00:00

abstract：:The distribution of P2X(2) purine receptor subunit immunoreactivity has been investigated in the mouse gastrointestinal tract. Immunoreactivity occurred in intraganglionic laminar endings (IGLEs) associated with myenteric ganglia throughout the gastrointestinal tract. In the esophagus, IGLEs supplied every myenteric g...

journal_title：Cell and tissue research

authors： Castelucci P,Robbins HL,Furness JB

更新日期：2003-05-01 00:00:00

abstract：:We have developed a primary cell culture system of antennal mechanoreceptor neurons from early-stage pupal sphinx moth Manduca sexta. Dissociated neurons from the moth antennae differentiated, grew and survived for several weeks in a conditioned culture medium. Bipolar neurons with soma diameters of 10-25 microns from...

journal_title：Cell and tissue research

authors： Torkkeli PH,French AS

更新日期：1999-08-01 00:00:00

abstract：:Intercellular communication between smooth muscle cells is crucial for contractile behaviour in normal and pathologically altered urinary bladder. Since the study of coupling is difficult in situ, we established cell cultures of bladder smooth muscle cells to analyse coupling mechanisms. Microinjection of Lucifer yell...

journal_title：Cell and tissue research

authors： Neuhaus J,Wolburg H,Hermsdorf T,Stolzenburg JU,Dorschner W

更新日期：2002-08-01 00:00:00

abstract：:The problem of the blood-brain barrier in the pineal organ of the rainbow trout, Salmo gairdneri, was investigated following intraperitoneal or intracardial injections of several tracers and dyes with different molecular weights. As demonstrated at the light-microscopic level, repeated injections of trypan blue or hor...

journal_title：Cell and tissue research

authors： Omura Y,Korf HW,Oksche A

更新日期：1985-01-01 00:00:00

abstract：:A somatostatin-like substance is demonstrated by light microscopic immunohistochemistry (PAP-method) in perikarya and cell processes of the retina of adult and infant rats. These perikarya are identified according to their size, arrangement and distribution. Each of the first two neuronal orders (receptors, bipolar ce...

journal_title：Cell and tissue research

authors： Kirsch B,Leonhardt H

更新日期：1979-01-01 00:00:00

abstract：:To obtain more information concerning the origin of dendritic reticulum cells, the development of germinal centers in the spleens of rabbits was investigated by conventional light microscopy, enzyme histochemistry, and electron microscopy. Washed sheep erythrocytes were used as antigen. Splenic tissue was examined on ...

journal_title：Cell and tissue research

authors： Heusermann U,Zurborn KH,Schroeder L,Stutte HJ

更新日期：1980-01-01 00:00:00

abstract：:R*-cells of the digestive gland of Carcinus maenas have been investigated functionally and morphologically. A comparison of the capacity of separated cell suspensions to synthesize glycogen gave support to the hypothesis that R and R* cells belong to the same cell line. The unexpected observation of R* cells in gastri...

journal_title：Cell and tissue research

authors： Loret SM,Devos PE

更新日期：1992-01-01 00:00:00

abstract：:This report describes a phenotyping study of differentiating human skeletal muscle cells in tissue culture. Satellite cells (adult myoblasts), isolated from biopsy material, showed a proliferative behaviour in high-nutrition medium, but fused to form myotubes when grown in low-nutrition medium. The expression and stru...

journal_title：Cell and tissue research

authors： van der Ven PF,Schaart G,Jap PH,Sengers RC,Stadhouders AM,Ramaekers FC

更新日期：1992-10-01 00:00:00

abstract：:Ultrastructural studies of pancreatic islets have suggested that crinophagy provides a possible mechanism for intracellular degradation of insulin in the insulin-producing B-cells. In the present study, a quantitative estimation of crinophagy in mouse pancreatic islets was attempted by morphometric analysis of lysosom...

journal_title：Cell and tissue research

authors： Schnell AH,Swenne I,Borg LA

更新日期：1988-04-01 00:00:00

abstract：:alpha-Smooth muscle (alpha SM) actin of endothermic vertebrates is selectively recognized by the monoclonal antibody anti-alpha SM-1. Immunoreactivity to this antibody has been shown to be localized in the NH2-terminal sequence Ac-EEED (Chaponnier et al. 1994). Among terrestrial ectothermic vertebrates, two amphibian ...

journal_title：Cell and tissue research

authors： Di Rosa I,Panara F,Fagotti A,Simoncelli F,Chaponnier C,Gabbiani G,Pascolini R

更新日期：1995-09-01 00:00:00

abstract：:Using a somatostatin-gold conjugate of known biological activity, high affinity binding sites for this neuropeptide were visualized at cellular resolution on cultured diencephalic astrocytes and on frozen sections of the rat diencephalon. Binding could be completely suppressed in competition experiments with surplus u...

journal_title：Cell and tissue research

authors： Krisch B,Buchholz C,Mentlein R

更新日期：1991-02-01 00:00:00

abstract：:The expression of the gene for vasoactive intestinal polypeptide (VIP) and peptide histidine methionine (PHM) in the human gastrointestinal tract was studied by in situ hybridization and Northern blotting for PHM/VIP mRNA and immunocytochemistry using specific antisera against the bioactive peptides PHM and VIP. In th...

journal_title：Cell and tissue research

authors： Bredkjaer HE,Wulff BS,Emson PC,Fahrenkrug J

更新日期：1994-05-01 00:00:00

abstract：:Light and electron microscopy of the hypothalamic ventricle in neonatal rats demonstrate morphological specializations of the ventricular wall at the level of the premammillary region of the third ventricle. The morphological features are: (1) A ventricular recess that we have called the "hypothalamic dorso-lateral re...

journal_title：Cell and tissue research

authors： Menéndez A,Alvarez-Uría M

更新日期：1987-10-01 00:00:00

abstract：:Radiofrequency lesions were made in the lateral geniculate nuclei of six squirrel monkeys. The resulting degenerating terminals and their postsynaptic structures in layer IV of area 17 were quantitatively categorized on photomontages covering large areas of neuropil. Two to five days after the lesion, numerous axon te...

journal_title：Cell and tissue research

authors： Tigges M,Tigges J

更新日期：1979-02-28 00:00:00

abstract：:Human fibroblasts and HeLa cells were treated with bunaftine (N-butyl-N-/2-(diethylamino)ethyl/-1-naphthalenecarboxamide ) in vitro. At concentrations of 0.5-2.0 mM, the drug caused contraction and rounding of the cells with loss of microvilli-like processes. Aggregates of dense, partly granular, partly fibrillar mate...

journal_title：Cell and tissue research

authors： Moskalewski S,Thyberg J

更新日期：1984-01-01 00:00:00

abstract：:Taste buds and the peripheral nerves innervating them are two important components of the peripheral gustatory system. They require appropriate connections for the taste system to function. Neurotrophic factors play crucial roles in the innervation of peripheral sensory organs and tissues. Both brain-derived neurotrop...

journal_title：Cell and tissue research

authors： Ito A,Nosrat CA

更新日期：2009-09-01 00:00:00

abstract：:The fine structure of the horny teeth of the lamprey, Entosphenus japonicus, was examined by light- and electron-microscopy. Most of the horny teeth consisted of two horny and two nonhorny layers. The primary horny layer was well keratinized, and the cells were closely packed and intensely interdigitated, being joined...

journal_title：Cell and tissue research

authors： Uehara K,Miyoshi S,Toh H

更新日期：1983-01-01 00:00:00

abstract：:The formaldehyde-induced fluorescence technique had shown 5-hydroxytryptamine-containing enteric neurons in the intestine of the teleost Platycephalus bassensis, but did not reveal such neurons in the intestine of Tetractenos glaber or Anguilla australis. Re-examination of these animals with 5-hydroxytryptamine immuno...

journal_title：Cell and tissue research

authors： Anderson C,Campbell G

更新日期：1988-01-01 00:00:00

abstract：:Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cell (MSC) characterized by multi-lineage differentiation making it an attractive choice for tissue regeneration. However, before DPSCs can be used for cell-based therapy, we have to understand their biological properties in response to intrinsic and extrin...

journal_title：Cell and tissue research

authors： Feng X,Feng G,Xing J,Shen B,Tan W,Huang D,Lu X,Tao T,Zhang J,Li L,Gu Z

更新日期：2014-05-01 00:00:00

abstract：:Autophagy (cellular self-consumption) is an adaptive stress response and an important aspect of adaption to mechanical loading. If mechanical forces are associated with autophagy regulation in periodontal ligament (PDL) fibroblasts is still unknown. The aim of this study was to analyze the influence of force magnitude...

journal_title：Cell and tissue research

authors： Memmert S,Damanaki A,Weykopf B,Rath-Deschner B,Nokhbehsaim M,Götz W,Gölz L,Till A,Deschner J,Jäger A

更新日期：2019-12-01 00:00:00

abstract：:In the central nervous system of the male domestic flow, metenkephalin (ENK) immunoreactive perikarya and fiber tracts as well as extensive but sharply delimited fiber networks were visualized by means of the PAP technique. The most striking results were: (1) The demonstration of an association of ENK-containing struc...

journal_title：Cell and tissue research

authors： Blähser S,Dubois MP

更新日期：1980-01-01 00:00:00