P2X(2) purine receptor immunoreactivity of intraganglionic laminar endings in the mouse gastrointestinal tract.

Abstract:

:The distribution of P2X(2) purine receptor subunit immunoreactivity has been investigated in the mouse gastrointestinal tract. Immunoreactivity occurred in intraganglionic laminar endings (IGLEs) associated with myenteric ganglia throughout the gastrointestinal tract. In the esophagus, IGLEs supplied every myenteric ganglion. The proportion of ganglia supplied decreased from 85% in the stomach to 10% in the ileum, and from 50% in the caecum to 15% in the distal colon. There was substantial loss of IGLEs from myenteric ganglia of all abdominal regions after bilateral subdiaphragmatic section of the vagus nerves. IGLEs in the esophagus consisted of dense clusters of punctate immunoreactive varicosities. In the stomach and duodenum they had prominent lamellar processes and irregular, but smaller, lamellae were found in other regions. Rare immunoreactive IGLEs occurred in the submucosa of the distal colon. P2X(2) receptor immunoreactivity was on the surfaces and in the cytoplasm of a minority of nerve cells in myenteric ganglia. It is concluded that P2X(2) purine receptor immunoreactivity is a feature of IGLEs in the mouse, and that P2X receptor agonists may modulate sensitivity of the IGLEs.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Castelucci P,Robbins HL,Furness JB

doi

10.1007/s00441-003-0715-3

keywords:

subject

Has Abstract

pub_date

2003-05-01 00:00:00

pages

167-74

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

312

pub_type

杂志文章
  • Neuroanatomical, immunocytochemical, and physiological studies of the pharyngeal retractor muscle and its putative regulatory neurons playing a role in withdrawal and feeding in the snail, Helix pomatia.

    abstract::We describe the neurons regulating two separate functions of the pharyngeal retractor muscle (PRM), namely sustained contraction during body withdrawal and rhythmic phasic contractions during feeding, in the snail, Helix pomatia. The distribution of central neurons innervating the PRM is organized into two main units;...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-005-1144-2

    authors: Hernádi L,Vehovszky A,Hiripi L,Györi J,Walker RJ,Elekes K

    更新日期:2005-08-01 00:00:00

  • Characterization of the population of phagocytic cells in thymic cell suspensions. A morphological and cytochemical study.

    abstract::Rat thymic phagocytic cells were characterized in vitro using various light- and electron-microscopical techniques. Thymic cell suspensions were mechanically prepared and enriched for non-lymphoid cells, which were predominantly phagocytic and of three types. Type I showed acid phosphatase (APh) activity in small gran...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00222183

    authors: Duijvestijn AM,Schutte R,Köhler YG,Korn C,Hoefsmit EC

    更新日期:1983-01-01 00:00:00

  • A second cell type in Stannius bodies of two euryhaline telecost species.

    abstract::In the corpuscles of Stannius of sticklebacks and eels two cell types are described of presumably endocrine nature. The predominating type, comparable to the cells observed in other species, responds to variation in calcium content of the medium and possibly produces a hypocalcemic hormone. The second cell type is unr...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219163

    authors: Bonga SE,Greven JA

    更新日期:1975-06-09 00:00:00

  • Increased expression of non-muscle myosin heavy chain-B in connective tissue cells of hypertrophic rat urinary bladder.

    abstract::Expression of the non-muscle myosin heavy chain-B (NM-MHC-B, also denoted as the embryonic smooth muscle myosin heavy chain, SMemb) was examined in rat urinary bladder during growth in response to a partial urinary outflow obstruction. Following obstruction, the weight of the urinary bladder increased more than five-f...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410000262

    authors: Sjuve R,Haase H,Ekblad E,Malmqvist U,Morano I,Arner A

    更新日期:2001-05-01 00:00:00

  • Developmental expression of GLUT2 in the rat retina.

    abstract::We previously demonstrated that GLUT2, a facilitated-diffusion glucose transporter isoform known to play critical roles in the regulation of systemic blood glucose level, is present at the apical ends of Müller cells in the rat retina. As a means of elucidating the ontogeny and possible role(s) of GLUT2 in the develop...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004419900099

    authors: Watanabe T,Nagamatsu S,Matsushima S,Kondo K,Motobu H,Hirosawa K,Mabuchi K,Kirino T,Uchimura H

    更新日期:1999-11-01 00:00:00

  • The glucose transport facilitator GLUT8 is predominantly associated with the acrosomal region of mature spermatozoa.

    abstract::The glucose transporter 8 (GLUT8) is a recently identified member of the family of sugar transport facilitators. In human tissues GLUT8 is predominantly expressed in testis in a gonadotropin-dependent manner. It is shown here that the onset of mRNA synthesis of GLUT8 during the maturation of mouse testis coincides wit...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-001-0499-2

    authors: Schürmann A,Axer H,Scheepers A,Doege H,Joost HG

    更新日期:2002-02-01 00:00:00

  • Lactation-associated redistribution of the glial fibrillary acidic protein within the supraoptic nucleus. An immunocytochemical study.

    abstract::Electron-microscopic evidence indicates that during conditions of high hormone demand such as lactation there is a dramatic reduction in the number of fine glial processes which are normally interposed between magnocellular neuroendocrine cell somata in the supraoptic nucleus (SON). The purpose of this study was to co...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00225557

    authors: Salm AK,Smithson KG,Hatton GI

    更新日期:1985-01-01 00:00:00

  • Immunohistochemical localization of laminin, neural cell adhesion molecule, collagen type IV and T-61 antigen in the embryonic retina of the Japanese quail by in vivo injection of antibodies.

    abstract::Antibodies against laminin (LN), fibronectin (FN), collagen type IV (Col IV), neural cell adhesion molecule (N-CAM), T-61 antigen, actin, tubulin and neurofilament protein were injected into the eyes of quail embryos (Coturnix coturnix japonica) of different ages. Twenty h after injection, the heads of the embryos wer...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00217320

    authors: Halfter W,Fua CS

    更新日期:1987-09-01 00:00:00

  • Access and distribution of exogenous substances in the intercellular clefts of the rat adenohypophysis.

    abstract::In model experiments with the use of horseradish peroxidase (HRP), two pathways of transport of substances to the adenohypophysis were studied, as well as the distribution of the tracer in the latter organ. The first pathway allows the tracer to penetrate from the intercellular milieu of the median eminence below the ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00214248

    authors: Krisch B,Buchheim W

    更新日期:1984-01-01 00:00:00

  • Improved visualization of the immunoreactive hypothalamo-neurohypophysial system by use of immuno-gold techniques.

    abstract::Ultrastructural post-embedding immuno-gold techniques were applied to the supraoptic nucleus and the neurohypophysis of mice and rats. The primary antibodies were three different monoclonal antineurophysins, used in protein A-gold and immunoglobulin-gold procedures. Conventional plastic embedding as well as hydrophili...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00221868

    authors: Castel M,Morris JF,Whitnall MH,Sivan N

    更新日期:1986-01-01 00:00:00

  • Spatial and temporal regulation of glycosylation during Drosophila eye development.

    abstract::Glycosylation plays an essential role during development, in processes such as morphogen distribution, cell-to-cell communication, and extracellular matrix formation. Glycosylation is regulated during development in both a spatial and temporal manner. This study presents a detailed description of glycan distribution f...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-009-0753-6

    authors: Yano H,Yamamoto-Hino M,Goto S

    更新日期:2009-04-01 00:00:00

  • Ultrastructure of free nerve endings in respiratory and squamous epithelium on the rat nasal septum.

    abstract::The distribution of nerve fibres in the mucosa of the nasal septum of the rat was investigated by means of transmission electron microscopy on transverse and tangential ultrathin sections. Near the basement membrane of respiratory and squamous epithelium, a rather dense network of unmyelinated nerve fibres occurs. Som...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00318751

    authors: Spit BJ,Bretschneider F,Hendriksen EG,Kuper CF

    更新日期:1993-11-01 00:00:00

  • Fine structure of seminiferous tubules from prenatally irradiated rats.

    abstract::The ultrastructure of the seminiferous tubules was studied in rats that had been subjected to whole body irradiation on the 19th day of gestation. The seminiferous tubules from 3 months-old irradiated animals are devoid of germ cells and contain only Sertoli cells. Compared with controls of the same age, the seminifer...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00218294

    authors: Abreu I,David-Ferreira JF

    更新日期:1982-01-01 00:00:00

  • Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. An enzyme-histochemical study.

    abstract::Dichloromethylene diphosphonate can be used for temporary elimination of macrophages in the spleen when administered after entrapment in liposomes. No comparable effect on the macrophages of the spleen was observed with free dichloromethylene diphosphonate or in the case of empty liposomes. Marginal metallophils on th...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00217308

    authors: van Rooijen N,van Nieuwmegen R

    更新日期:1984-01-01 00:00:00

  • Neuromedin U-immunoreactivity in the nervous system of the small intestine of the pig and its coexistence with substance P and CGRP.

    abstract::In the small intestine of the pig, neuromedin U (NMU)-immunoreactivity was mainly confined to the nerve plexus of the inner submucosal and mucosal regions. After colchicine treatment, a high number of immunoreactive nerve cell bodies was observed in the plexus submucosus internus (Meissner), whereas only a low number ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00239453

    authors: Timmermans JP,Scheuermann DW,Stach W,Adriaensen D,De Groodt-Lasseel MH,Polak JM

    更新日期:1989-11-01 00:00:00

  • Nerve fibers immunoreactive for substance P and calcitonin gene-related peptide in the cervical spinal ventral roots of the mouse.

    abstract::We demonstrate the existence of nerve fibers possessing substance P (SP) and calcitonin gene-related peptide (CGRP) immunoreactivity in the mouse cervical ventral roots. The distribution of the SP and CGRP fibers was similar, but CGRP fibers were generally more numerous. Both types entered the ventral pia mater or for...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00327774

    authors: Kimura M,Kishida R,Abe T,Goris RC,Kawai S

    更新日期:1994-08-01 00:00:00

  • Ultrastructural and cytological changes in the muscle fibers of the pectoralis of the giant Canada goose (Branta canadensis maxima) in disuse atrophy during molt.

    abstract::Adult male Branta canadensis maxima were collected from a nonmigratory feral population during their premolt, molt and postmolt phases. Lean dry weight of the pectoralis muscle decreased significantly (p less than or equal to 0.0001) during molt, as a result of disuse atrophy. Histochemical analysis revealed that the ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00215763

    authors: Rosser BW,George JC

    更新日期:1987-03-01 00:00:00

  • Loss of purinergic P2X receptor innervation in human detrusor and subepithelium from adults with sensory urgency.

    abstract::Purinergic P2X receptors associated with the parasympathetic nerves supplying human bladder smooth muscle (detrusor) are implicated in control of detrusor contractility. The relative abundance of all seven subtypes colocalised with synaptic vesicles on parasympathetic nerves was examined in specimens from normal adult...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-003-0788-z

    authors: Ray FR,Moore KH,Hansen MA,Barden JA

    更新日期:2003-12-01 00:00:00

  • Fine structural and immunohistochemical detection of collar enamel in the teeth of Polypterus senegalus, an actinopterygian fish.

    abstract::This is the first detailed report about the collar enamel of the teeth of Polypterus senegalus. We have examined the fine structure of the collar enamel and enamel organ of Polypterus during amelogenesis by light and transmission electron microscopy. An immunohistochemical analysis with an antibody against bovine amel...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-011-1305-4

    authors: Sasagawa I,Yokosuka H,Ishiyama M,Mikami M,Shimokawa H,Uchida T

    更新日期:2012-02-01 00:00:00

  • The ring nerve of the box jellyfish Tripedalia cystophora.

    abstract::Box jellyfish have the most elaborate sensory system and behavioural repertoire of all cnidarians. Sensory input largely comes from 24 eyes situated on four club-shaped sensory structures, the rhopalia, and behaviour includes obstacle avoidance, light shaft attractance and mating. To process the sensory input and conv...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-007-0393-7

    authors: Garm A,Poussart Y,Parkefelt L,Ekström P,Nilsson DE

    更新日期:2007-07-01 00:00:00

  • Cytological evidence for different types of cerebrospinal fluid-contacting subependymal cells in the preoptic and infundibular recesses of the frog.

    abstract::Blue-green fluorescent subependymal cells with intraventricular processes were shown by the fluorescent histochemical method to be distributed from the preoptic recess to the infundibular recess of the frog hypothalamus. Electron microscopy revealed at least two types of CSF-contacting subependymal cells, type 1 conta...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00221791

    authors: Nakai Y,Ochiai H,Shioda S,Ochi J

    更新日期:1977-01-20 00:00:00

  • Production of the long and short forms of MFG-E8 by epidermal keratinocytes.

    abstract::Mouse milk fat globule-EGF factor 8, MFG-E8, is the ortholog to the human mammary tumor marker, lactadherin, and comprises two spliced variants, the L and S forms. Recent studies have suggested that MFG-E8-L produced by macrophages and Langerhans cells in the skin serves as a linker between phagocytic cells and apopto...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-005-1148-y

    authors: Watanabe T,Totsuka R,Miyatani S,Kurata S,Sato S,Katoh I,Kobayashi S,Ikawa Y

    更新日期:2005-08-01 00:00:00

  • The insulin receptor is differentially expressed in somatic and visceral primary sensory neurons.

    abstract::Recent studies demonstrated the expression of the insulin receptor (InsR) and its functional interaction with the transient receptor potential vanilloid type 1 receptor (TRPV1) in primary sensory neurons (PSNs). The present study was undertaken to reveal the target-specific expression of the InsR and its co-localizati...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-018-2868-0

    authors: Lázár BA,Jancsó G,Nagy I,Horváth V,Sántha P

    更新日期:2018-11-01 00:00:00

  • Immunohistochemical evidence for a magnocellular somatostatin cell group in the anterior paraventricular thalamus of the rat.

    abstract::By use of the indirect immunofluorescence technique a small group of large somatostatin-positive neurons is described in the subependymal area of the anterior paraventricular thalamus of the male rat. Retrograde-tracing experiments suggest that they project to areas outside the blood-brain barrier. ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00215212

    authors: Ceccatelli S,Meister B,Hökfelt T,Elde R

    更新日期:1986-01-01 00:00:00

  • The ultrastructure of the protonephridial flame cell of the freshwater planarian Bdellocephala brunnea.

    abstract::The protonephridial flame cell of the freshwater planarian Bdellocephala brunnea was studied by electron microscopy. This basketlike cell with luminal cilia and fenestrae is known as a cyrtocyte. Careful examination revealed the actual continuity of the fenestrae over the surface of the cell and the microvillous natur...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00237973

    authors: Ishii S

    更新日期:1980-01-01 00:00:00

  • FoxO3a suppression and VPS34 activity are essential to anti-atrophic effects of leucine in skeletal muscle.

    abstract::Our aim is to gain insight into the mechanisms underlying the anti-atrophic effects of leucine, namely, the way that this amino acid can restrain the up-regulation of MuRF1 and Mafbx/Atrogin-1 in muscle atrophy. Male rats received dietary leucine supplementation for 1-3 days, during which time their hind limbs were im...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-017-2614-z

    authors: Baptista IL,Silvestre JG,Silva WJ,Labeit S,Moriscot AS

    更新日期:2017-08-01 00:00:00

  • Immuno-cytochemical demonstration, in the external region of the amphibian median eminence, of separate vasotocinergic and mesotocinergic nerve fibres.

    abstract::By means of single and double immuno-enzyme cytochemical staining techniques, it was shown that the external region of the amphibian median eminence contains separate vasotocinergic and mesotocinergic nerve fibres. Moreover, it was demonstrated that the vasotocinergic fibres also contain neurophysin. In animals in whi...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00221117

    authors: Dierickx K,Vandesande F

    更新日期:1977-02-02 00:00:00

  • Transmission and scanning electron-microscopic observations on tanycytes in the mediobasal hypothalamus and the median eminence of adrenalectomized rats.

    abstract::Tanycytes in the median eminence (ME) of the rat exhibit morphological features suggesting their possible participation in transport phenomena. After adrenalectomy, which modifies the hypothalamo-hypophyseal axis, they undergo morphological changes characterized by an accumulation of lipid droplets, an increased numbe...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00215708

    authors: Brion JP,Depierreux M,Couck AM,Flament-Durand J

    更新日期:1982-01-01 00:00:00

  • Atrial natriuretic peptide binding in rat placenta, yolk sac, decidua, and maternal placental vessels.

    abstract::Using in vitro autoradiography, binding sites of 125I-ANP (atrial natriuretic peptide) were localized in the rat placenta, visceral yolk sac, and decidua at 16, 18, and 20 days of gestation. There was diffuse binding over the labyrinthine region of the placenta and an intense binding over the decidual gland and viscer...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00302744

    authors: Scott JN

    更新日期:1993-05-01 00:00:00

  • Light and electron microscopic studies on the excretory system of Macrobiotus richtersi Murray, 1911 (Eutardigrada).

    abstract::The excretory system of Macrobiotus richtersi consists of one dorsal and two lateral components and shows a high degree of structural complexity. In each of these a tricellular external lobe and a column can be distinguished, the two parts being connected distally. The surface of the lobe cells is increased by deep ba...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00239339

    authors: Weglarska B

    更新日期:1980-01-01 00:00:00