Atrial natriuretic peptide binding in rat placenta, yolk sac, decidua, and maternal placental vessels.

Abstract:

:Using in vitro autoradiography, binding sites of 125I-ANP (atrial natriuretic peptide) were localized in the rat placenta, visceral yolk sac, and decidua at 16, 18, and 20 days of gestation. There was diffuse binding over the labyrinthine region of the placenta and an intense binding over the decidual gland and visceral yolk sac. In the yolk sac, ANP localized over the cores of the villi where it may be involved with the regulation of transport across the membranes or the flow of blood through the vitelline vessels. Of particular interest was binding over the maternal blood vessels supplying the decidual region and placenta. Receptors were located on the endothelial cells and smooth muscle cells of the arteries and veins, indicating that ANP may be involved with regional regulation of blood flow to the placenta.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Scott JN

doi

10.1007/BF00302744

subject

Has Abstract

pub_date

1993-05-01 00:00:00

pages

391-4

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

272

pub_type

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