Abstract:
:Dichloromethylene diphosphonate can be used for temporary elimination of macrophages in the spleen when administered after entrapment in liposomes. No comparable effect on the macrophages of the spleen was observed with free dichloromethylene diphosphonate or in the case of empty liposomes. Marginal metallophils on the boundary between white pulp and marginal zone as well as macrophages in the marginal zone and red pulp disappeared from the spleen within one day and remained largely absent for about a week. After this time cells reappeared slowly, and at approximately four weeks after injection their presence in the spleen did not differ from that in control animals. Marginal metallophils and macrophages in the spleen were demonstrated by use of enzyme-histochemical methods and by their capacity to ingest carbon particles.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
van Rooijen N,van Nieuwmegen Rdoi
10.1007/BF00217308subject
Has Abstractpub_date
1984-01-01 00:00:00pages
355-8issue
2eissn
0302-766Xissn
1432-0878journal_volume
238pub_type
杂志文章abstract::Two dozen hybrid clones were produced by fusion of diploid embryonic stem (ES) cells positive for green fluorescent protein (GFP) with tetraploid fibroblasts derived from DD/c and C57BL-I(I)1RK mice. Cytogenetic analysis demonstrated that most cells from these hybrid clones contained near-hexaploid chromosome sets. Ad...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-0987-3
更新日期:2010-06-01 00:00:00
abstract::Glycosylation plays an essential role during development, in processes such as morphogen distribution, cell-to-cell communication, and extracellular matrix formation. Glycosylation is regulated during development in both a spatial and temporal manner. This study presents a detailed description of glycan distribution f...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-009-0753-6
更新日期:2009-04-01 00:00:00
abstract::Type-A spermatogonia can be found in different locations throughout the germinal epithelium of human seminiferous tubules. Generally they represent the population of germ cells adjacent to the basal lamina, but under special conditions they may be located in the adluminal compartment. This aberrant location is found n...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216510
更新日期:1984-01-01 00:00:00
abstract::Antithrombin (AT), which is mainly synthesized in the liver, is an acute-phase plasma protein in mammalian species. Here, we demonstrated that sheep anti-human AT antibody cross-reacted with the humoral fluids in amphioxus Branchiostoma belcheri tsingtauense as well as human serum. The concentration of AT in the humor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0088-x
更新日期:2006-03-01 00:00:00
abstract::The nine-banded armadillo possesses a salivary bladder which is a dilated portion of the main duct of the submandibular gland at its origin. The wall of the bladder is composed of an epithelium, a submucosa and a thick coat of skeletal muscle. The ultrastructure of the epithelium reveals that it is complex and consist...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219609
更新日期:1976-06-28 00:00:00
abstract::The occurrence of neurons possessing high-affinity uptake sites for GABA was studied in the myenteric plexus of the guinea-pig ileum, caecum, and proximal and distal colon, the rat proximal colon, and the chicken gizzard with the use of 3H-GABA and autoradiography. Experiments were carried out on plexuses that had bee...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217417
更新日期:1983-01-01 00:00:00
abstract::Somatostatin-like immunoreactivity was localized in nerve cell bodies and nerve terminals in the cat coeliac ganglion. Two types of somatostatin-immunoreactive cell bodies were revealed, the first being large (diameter 35 microns), numerous and weakly labelled, whereas the second was considerably smaller (diameter 10....
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327290
更新日期:1991-03-01 00:00:00
abstract::In contrast to the vitellolysis zone which is involved in the degradation of the yolk, the cytoplasmic zone of the yolk syncytial layer, composed of many cytoplasmic organelles, is implicated in a secretory process. The granular endoplasmic reticulum of the latter is extremely well developed and organized into trabecu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236349
更新日期:1979-01-30 00:00:00
abstract::The LIM homeodomain transcription factor Lmx1a shows a dynamic expression in the developing mouse ear that stabilizes in the non-sensory epithelium. Previous work showed that Lmx1a functional null mutants have an additional sensory hair cell patch in the posterior wall of a cochlear duct and have a mix of vestibular a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-03163-y
更新日期:2020-06-01 00:00:00
abstract::Expression of the non-muscle myosin heavy chain-B (NM-MHC-B, also denoted as the embryonic smooth muscle myosin heavy chain, SMemb) was examined in rat urinary bladder during growth in response to a partial urinary outflow obstruction. Following obstruction, the weight of the urinary bladder increased more than five-f...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000262
更新日期:2001-05-01 00:00:00
abstract::Four months after the selective ablation of inner hair cells by carboplatin, the interdental cell epithelium exhibited dilated intercellular spaces and cytosolic vacuoles not seen in controls. In addition, the wide, often electron-lucent phalanges observed in the interdental cells of the normal chinchilla collapsed in...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000253
更新日期:2000-10-01 00:00:00
abstract::The development of the heterophil granulocytes in the bone marrow of the guinea pig is described. During the maturation of these cells, three types of granule are formed, not only the azurophil and specific granules already described in other mammals but also a third type of granule referred to here as the nucleated g...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220388
更新日期:1978-11-20 00:00:00
abstract::The antioxidant enzymes superoxide dismutase, glutathione peroxidase, and catalase were measured in the rete mirabile and gas gland epithelium area of the swim bladder of the toadfish Opsanus tau. When the concentration of enzyme in the swim bladder was compared with the concentration in other organs (kidney, heart, g...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00210458
更新日期:1981-01-01 00:00:00
abstract::PU.1, which is a transcription factor, promotes the terminal differentiation of alveolar macrophages (AMs). Its expression is regulated by granulocyte/macrophage colony-stimulating factor (GM-CSF). In this study of AMs in newborn rats, we performed immunohistochemical staining, acid phosphatase staining, reverse trans...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0405-7
更新日期:2007-07-01 00:00:00
abstract::By means of single and double immuno-enzyme cytochemical staining techniques, it was shown that the external region of the amphibian median eminence contains separate vasotocinergic and mesotocinergic nerve fibres. Moreover, it was demonstrated that the vasotocinergic fibres also contain neurophysin. In animals in whi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221117
更新日期:1977-02-02 00:00:00
abstract::The present study attempts to elucidate the role of TRPV1 cation channel receptor on primary repair in an incision-wounded mouse cornea in vivo. Previous study revealed that blocking TRPV1 suppressed myofibroblast formation and expression of transforming growth factor β1 (TGFβ1) in cultured keratocytes or ocular fibro...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2878-y
更新日期:2018-11-01 00:00:00
abstract::The midgut cells of Tomocerus minor (Insecta, Collembola) were examined with the electron microscope and cytochemically. The midgut epithelium consists of a series of cells characterised by numerous mineral concretions scattered throughout the cytoplasm. Mitochondria are abundant; microvilli are well developed at the ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236347
更新日期:1979-01-30 00:00:00
abstract::Chronological changes in renal glomerular morphology and plasma renin activity were investigated during active and hibernating periods in the golden-mantled ground squirrel Spermophilus lateralis. The objective of this study was to determine whether the glomerular endothelium, visceral epithelium (podocytes), basement...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327750
更新日期:1990-10-01 00:00:00
abstract::The present electron microscopic autoradiographic study includes a quantitative analysis of osteoclasts in vitro using tritiated leucin as a protein tracer. A significant increase in the grain density over the ruffled border and the underlying resportion zone was demonstrated two hours post pulse whereas the grain den...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219726
更新日期:1976-04-28 00:00:00
abstract::An attempt has been made to reveal which of the nine different types of synapses in the fundus striati, discriminated in a previous study, degenerate following experimental lesions in the parafasciculo-center median complex of the cat. Two types of synaptic contacts were found to be degenerated two days after the lesi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226045
更新日期:1976-09-06 00:00:00
abstract::Neurofilaments, which are exclusively found in nerve cells, are one of the earliest recognizable features of the maturing nervous system. The differential distribution of neurofilament proteins in varying degrees of phosphorylation within a neuron provides the possibility of selectively demonstrating either somata and...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051013
更新日期:1998-03-01 00:00:00
abstract::Marked changes in mice pubic symphysis occur by the end of pregnancy. Tissue remodeling involves a dynamic balance between cell proliferation and programmed cell death as well as changes in the extracellular matrix components. Therefore, it is important to consider both of these cellular behaviors when investigating t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0463-x
更新日期:2007-10-01 00:00:00
abstract::The adrenal gland of mammals contains high concentrations of peripheral-type benzodiazepine receptors (PBR) and diazepam-binding inhibitor (DBI), a polypeptide which acts as an endogenous ligand for PBR. The aim of the present study was to investigate the localization of DBI and PBR in the adrenal gland of the frog Ra...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050551
更新日期:1996-03-01 00:00:00
abstract::Maturing erythroblasts and erythrocytes were studied in chickens and adult hens to provide more information on the presence and frequency of various nucleolar types in these cells. Nucleoli were present at all stages of erythroblastic and erythrocytic development except in the case of a few reticulocytes and the matur...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00209211
更新日期:1975-09-17 00:00:00
abstract::Modulation of the actin cytoskeleton in chondrocytes has been used to prevent or reverse dedifferentiation and to enhance protein synthesis. We have hypothesized that an actin-modifying agent, staurosporine, could be used with fibrochondrocytes to increase the gene expression and synthesis of critical fibrocartilage p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0705-6
更新日期:2008-12-01 00:00:00
abstract::Rat thymic phagocytic cells were characterized in vitro using various light- and electron-microscopical techniques. Thymic cell suspensions were mechanically prepared and enriched for non-lymphoid cells, which were predominantly phagocytic and of three types. Type I showed acid phosphatase (APh) activity in small gran...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222183
更新日期:1983-01-01 00:00:00
abstract::The analysis of myenteric neurons is becoming increasingly important for the assessment of enteric nervous system injury and degeneration occurring in motor disorders of the gut. Limited information is presently available on the quantitative estimation of myenteric neurons and glial cells in paraffin-embedded colonic ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-009-0770-5
更新日期:2009-05-01 00:00:00
abstract::Electron microscopy of the pineal receptor cells in light- and dark-adapted brook trout, Salvelinus fontinalis and the rainbow trout, Salmo gairdneri, revealed no significant differences in the tubular and filamentous elements of the inner segment, neck and supranuclear regions. However, changes in synaptic relations ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234177
更新日期:1980-01-01 00:00:00
abstract::In three mature monkeys (Macaca fascicularis; 3.5 +/- 0.3 kg in weight), the labial, buccal and soft-palate mucosae were examined morphologically and stereologically. Using fixation by perfusion, standardized methods of tissue preparation and morphometric analysis at the light-microscopic level, the gross dimensions (...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213740
更新日期:1984-01-01 00:00:00
abstract::Neuropeptide F in invertebrates is a homolog of neuropeptide Y in mammals and it is a member of FMRFamide-related peptides. In arthropods, such as insects, there are two types of neuropeptide F comprising long neuropeptide F (NPF) and short neuropeptide F (sNPF). Both NPFs are known to play a crucial role in the regul...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-02999-8
更新日期:2019-06-01 00:00:00