Nerve fibers immunoreactive for substance P and calcitonin gene-related peptide in the cervical spinal ventral roots of the mouse.

Abstract:

:We demonstrate the existence of nerve fibers possessing substance P (SP) and calcitonin gene-related peptide (CGRP) immunoreactivity in the mouse cervical ventral roots. The distribution of the SP and CGRP fibers was similar, but CGRP fibers were generally more numerous. Both types entered the ventral pia mater or formed hairpin loops, but they did not enter the spinal cord directly through these roots. SP and CGRP fibers in the ventral roots were thin and had many varicosities. We suggest that these SP and CGRP fibers are involved not only in a sensory mechanism, but also in other functions, via the release of SP and CGRP from varicosities in the ventral roots.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Kimura M,Kishida R,Abe T,Goris RC,Kawai S

doi

10.1007/BF00327774

subject

Has Abstract

pub_date

1994-08-01 00:00:00

pages

273-8

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

277

pub_type

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