The bridge-partitioning complex is absent in a distinct type of defective germ cell division in the gonads of the golden hamster.


:Intercellular bridges (IBs) connecting the cytoplasms of a defined type of defective germ cell division ("arrested mitoses") in male and female gonads of the immature golden hamster were studied by electron microscopy. In both sexes, such cells appear at the time when germ cells switch from mitotic proliferation to the onset of meiotic prophase, i.e., during a short perinatal period in the female and during pubertal maturation in the male golden hamster. These cells are arrested and finally degenerate. IBs of these cells completely lack the bridge-partitioning complex (BPC), a structure composed of a stack of transverse endomembrane cisternae which normally fills the IBs during subsequent divisions of bridge-connected germ cells. This unique exception from the usual course of clonal proliferation of mammalian germ cells has several implications: (1) The supposed barrier function of the BPC is missing in the defective germ cell divisions; (2) the failure to form the BPC might be related to a disturbed microtubule apparatus in the cells; (3) the absence of the BPC possibly reflects the influence of conflicting environmental signals, inducing both mitotic and early meiotic mechanisms in the cells at this crucial point of gametogenesis.


Cell Tissue Res


Cell and tissue research


Miething A





Has Abstract


2002-04-01 00:00:00












  • Transplantation of bone marrow-derived MSCs improves renal function and Na++K+-ATPase activity in rats with renovascular hypertension.

    abstract::Renovascular hypertension (RVH) is a progressive disease, leading to chronic kidney disease when untreated and no specific treatment is available. Therefore, development of new therapeutic modalities is imperative. RVH is triggered by renal artery stenosis and subsequent renin-angiotensin-aldosterone system activation...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Lira R,Oliveira M,Martins M,Silva C,Carvalho S,Stumbo AC,Cortez E,Verdoorn K,Einicker-Lamas M,Thole A,de Carvalho L

    更新日期:2017-08-01 00:00:00

  • Changes in neurotrophin-3 messenger RNA expression patterns in the prenatal rat tongue suggest guidance of developing somatosensory nerves to their final targets.

    abstract::While brain-derived neurotrophic factor (BDNF) messenger RNA (mRNA) has been localized in the developing gustatory epithelium, little information is available about neurotrophin-3 (NT-3) mRNA expression pattern in the prenatal developing gustatory and lingual epithelium. In the present study, using in situ hybridizati...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Nosrat CA,Olson L

    更新日期:1998-06-01 00:00:00

  • Immunolocalization of inhibin alpha-subunit in the human testis. A light- and electron-microscopy study.

    abstract::The localization of inhibin alpha-subunit in the human testis was studied at the light- and electron-microscope level with immunostaining techniques. Antibodies against specific fragments of porcine and human inhibin alpha-subunits were utilized. At light microscopy, inhibin alpha-subunit immunoreactivity was detected...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Vannelli GB,Barni T,Forti G,Negro-Vilar A,Vale W,Serio M,Balboni GC

    更新日期:1992-08-01 00:00:00

  • The Ca(2+)-binding protein calretinin is selectively enriched in a subpopulation of the epithelial rests of Malassez.

    abstract::During tooth development, the inner and outer enamel epithelia fuse by mitotic activity to produce a bilayered epithelial sheath termed Hertwig's epithelial root sheath (HERS). The epithelial rests of Malassez (ERM) are the developmental residues of HERS and remain in the adult periodontal ligament (PDL). Although the...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Korkmaz Y,Klinz FJ,Beikler T,Blauhut T,Schneider K,Addicks K,Bloch W,Raab WH

    更新日期:2010-12-01 00:00:00

  • Histone methylation during neural development.

    abstract::Post-translational modification of histone proteins, such as the methylation of lysine and arginine residues, influences the higher order of chromatin and leads to gene activation or silencing. Histone methyltransferases or demethylases actively add or remove various methylation marks in a cell-type-specific and conte...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Roidl D,Hacker C

    更新日期:2014-06-01 00:00:00

  • Responses of pineal photoreceptors in the brook and rainbow trout.

    abstract::Electron microscopy of the pineal receptor cells in light- and dark-adapted brook trout, Salvelinus fontinalis and the rainbow trout, Salmo gairdneri, revealed no significant differences in the tubular and filamentous elements of the inner segment, neck and supranuclear regions. However, changes in synaptic relations ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Omura Y,Ali MA

    更新日期:1980-01-01 00:00:00

  • Distribution and characterisation of CCK containing enteroendocrine cells of the mouse small and large intestine.

    abstract::There is general consensus that enteroendocrine cells, EEC, containing the enteric hormone cholecystokinin (CCK) are confined to the small intestine and predominate in the duodenum and jejunum. Contrary to this, EEC that express the gene for CCK have been isolated from the large intestine of the mouse and there is evi...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Fakhry J,Wang J,Martins P,Fothergill LJ,Hunne B,Prieur P,Shulkes A,Rehfeld JF,Callaghan B,Furness JB

    更新日期:2017-08-01 00:00:00

  • Morphology of horizontal cells in the frog retina.

    abstract::Two types of horizontal cells, H1 and H2, were classified using the Golgi technique on flat mounts of the retina of the frog. Cell type H1 possesses rather short, thick dendrites; the diameter of its dendritic field ranges from 40-90 micrometers. H2-cell displays long and thin dendrites; the diameter of its dendritic ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Stephan P,Weiler R

    更新日期:1981-01-01 00:00:00

  • Role of region-distinctive expression of Rac1 in regulating fibronectin arrangement during palatal shelf elevation.

    abstract::Palatal shelf elevation is a crucial process in palate development, with the contribution of various factors. Disturbances in any factor during this process result in cleft palate. Prior to palatal shelf elevation starting from embryonic day 12.5, the Rac1 expression level in the bend region of the mid-palatal shelf p...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Tang Q,Li L,Jin C,Lee JM,Jung HS

    更新日期:2015-09-01 00:00:00

  • Gdf-15 deficiency does not alter vulnerability of nigrostriatal dopaminergic system in MPTP-intoxicated mice.

    abstract::Growth/differentiation factor-15 (Gdf-15) is a member of the transforming growth factor-β (Tgf-β) superfamily and has been shown to be a potent neurotrophic factor for midbrain dopaminergic (DAergic) neurons both in vitro and in vivo. Gdf-15 has also been shown to be involved in inflammatory processes. The aim of this...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Machado V,Gilsbach R,Das R,Schober A,Bogatyreva L,Hauschke D,Krieglstein K,Unsicker K,Spittau B

    更新日期:2016-08-01 00:00:00

  • Developmental immunohistology of melanotrophs in Xenopus laevis tadpoles.

    abstract::The adenohypophysial primordium of Xenopus laevis tadpoles at stages 33/34 to 46 (Nieuwkoop and Faber, 1956) were examined immunohistologically for alpha-MSH, beta-MSH and ACTH. beta-MSH was demonstrated from stage 37/38 onwards, and alpha-MSH from stage 39. No signs of ACTH production were detected. alpha-MSH and bet...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Erik N,Nyholm I,Doerr-Schott J

    更新日期:1977-05-16 00:00:00

  • Immunohistochemical localization of (neuro)peptide hormones in endocrine cells and nerves of the gut of a stomachless teleost fish, Barbus conchonius (Cyprinidae).

    abstract::Enteroendocrine cells containing glucagon-, substance P-, neurotensin- and VIP-like substances have been demonstrated immunocytochemically in the gut of Barbus conchonius. Mainly based on the distribution of the immunoreactive endocrine cells in this and a previous study, at least eight different enteroendocrine cell ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Rombout JH,Reinecke M

    更新日期:1984-01-01 00:00:00

  • Ommatidial structure in relation to turnover of photoreceptor membrane in the locust.

    abstract::In the compound eye of the locust, Locusta, the cross-sectional area of the rhabdoms increases at "dusk" by 4.7-fold due to the rapid assembly of new microvillar membrane, and decreases at "dawn" by a corresponding amount as a result of pinocytotic shedding from the microvilli. The rhabdoms at night have more and long...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Williams DS

    更新日期:1982-01-01 00:00:00

  • High-resolution scanning electron-microscopic studies on the three-dimensional structure of mitochondria and sarcoplasmic reticulum in the different twitch muscle fibers of the frog.

    abstract::The three-dimensional structure of the mitochondria and sarcoplasmic reticulum (SR) in the three types of twitch fibers, i.e., the red, white and intermediate skeletal muscle fibers, of the vastus lateralis muscle of the Japanese meadow frog (Rana nigromaculata nigromaculata Hallowell) was examined by high resolution ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Ogata T,Yamasaki Y

    更新日期:1987-12-01 00:00:00

  • Horseradish peroxidase in axons of the dorsal funiculi of the cat: distribution after an injection of the enzyme into the dorsal column nuclei.

    abstract::Horseradish peroxidase (HRP) was injected into the left dorsal column nuclei of adult cats. Large dorsal funiculi axons of the C3, C5, C8 and L7 segments were searched for HRP-activity after 12, 24, 36 and 48h using light and electron microscopy. Accumulations of intra-axonal HRP-positive bodies occurred at nodes of R...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Fabricius C,Berthold CH,Gatzinsky KP

    更新日期:1996-01-01 00:00:00

  • Expression of mRNAs encoding for growth factors, ECM molecules, and MMP13 in mono-cultures and co-cultures of human periodontal ligament fibroblasts and alveolar bone cells.

    abstract::Although the function and effects of many growth factors and extracellular matrix (ECM) molecules have been described for several periodontal tissues in vivo and in vitro, the molecular interactions involved in the communication between cells of the periodontal ligament and the alveolar bone are poorly understood. To ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Winter S,Kohl A,Huppertz A,Herold-Mende C,Wiest T,Komposch G,Tomakidi P

    更新日期:2005-03-01 00:00:00

  • Kainate receptors.

    abstract::Kainate receptors form a family of ionotropic glutamate receptors that appear to play a special role in the regulation of the activity of synaptic networks. This review first describes briefly the molecular and pharmacological properties of native and recombinant kainate receptors. It then attempts to outline the gene...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Pinheiro P,Mulle C

    更新日期:2006-11-01 00:00:00

  • Concanavalin A-binding glycoproteins in the subcommissural and the pineal organ of the sheep (Ovis aries). A fluorescence-microscopic and electrophoretic study.

    abstract::Glycoproteins rich in mannosyl or glucosyl residues were analyzed in the subcommissural organ (SCO) and the pineal organ of the sheep (Ovis aries). By use of concanavalin A labelled with fluorescein isothiocyanate, fluorescent material was found both in ependymal and hypendymal cells of the SCO. In the pineal organ, e...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Meiniel R,Molat JL,Meiniel A

    更新日期:1986-01-01 00:00:00

  • Ultrastructural changes in pancreatic beta cells treated with NGF and dbcAMP.

    abstract::Nerve growth factor (NGF) induces morphological and physiological changes in cultured pancreatic beta-cells, including the extension of neurite-like processes. This latter effect is potentiated by dibutyryl cAMP (dbcAMP). beta-cells cultured under these conditions maintain their immunoreactivity to insulin and gamma-a...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: González del Pliego M,Aguirre-Benítez E,Sánchez-Soto MC,Larrieta ME,Velázquez-Carranza A,Vidaltamayo R,Meza-Mora M,Zepeda-Rodríguez A,Hernández-Falcón J,Hiriart M

    更新日期:2001-09-01 00:00:00

  • Survival of rat MCH (melanin-concentrating hormone) neurons in hypothalamus slice culture: histological, pharmacological and molecular studies.

    abstract::Hypothalamic slices containing the lateral hypothalamic area (LHA) were prepared from 6- to 8-day-old rats and maintained in stationary culture for up to 35 days in order to analyse how well the melanin-concentrating hormone (MCH) neurons survived. As previously reported for other brain areas, this method yielded a lo...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Bayer L,Jacquemard C,Fellmann D,Griffond B

    更新日期:1999-07-01 00:00:00

  • Expression of urocortin and corticotropin-releasing hormone receptors in the horse thyroid gland.

    abstract::Urocortin (UCN) is a 40-amino-acid peptide and a member of the corticotropin-releasing hormone (CRH) family, which includes CRH, urotensin I, sauvagine, UCN2 and UCN3. The biological actions of CRH family peptides are mediated via two types of G-protein-coupled receptors, namely CRH type 1 receptor (CRHR1) and CRH typ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Squillacioti C,De Luca A,Alì S,Paino S,Liguori G,Mirabella N

    更新日期:2012-10-01 00:00:00

  • Retrograde labeling of regenerated electromotor neurons with HRP in a teleost fish, Sternarchus albifrons: relation to cell death.

    abstract::Back-labeling of regenerated electromotor neurons in the teleost Sternarchus albifrons was performed to test the hypothesis that, in regenerated spinal cord, incorrectly located electromotor neurons are eliminated because their axons do not reach the correct target area (electric organ). In each cross section examined...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Anderson MJ,Fong HL,Waxman SG

    更新日期:1985-01-01 00:00:00

  • Serum-free cryopreservation of porcine hepatocytes.

    abstract::The use of porcine hepatocytes in xenotransplantation, bioartificial liver support or pharmacological approaches demands serum-free cryopreservation protocols yielding high quality, viable, functional hepatocytes. Here, primary porcine hepatocytes were frozen without serum in liquid nitrogen by the use of a computer-a...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Müller P,Aurich H,Wenkel R,Schäffner I,Wolff I,Walldorf J,Fleig WE,Christ B

    更新日期:2004-07-01 00:00:00

  • Cell-specific localization of the sulphydryl oxidase QSOX in rat peripheral tissues.

    abstract::Rat quiescin/sulphydryl oxidase (rQSOX) introduces disulphide bridges into peptides and proteins with the reduction of molecular oxygen to hydrogen peroxide. Its occurrence has been previously highlighted in a wide range of organs by reverse transcription-polymerase chain reaction (RT-PCR) and Northern blot analyses, ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Tury A,Mairet-Coello G,Esnard-Fève A,Benayoun B,Risold PY,Griffond B,Fellmann D

    更新日期:2006-01-01 00:00:00

  • Enzyme histochemical characteristics of osteoblasts and mononucleated osteoclasts in a teleost fish with acellular bone (Oreochromis niloticus, Cichlidae).

    abstract::Bone resorption by mononucleated cells was studied in the acellular bone of a teleost fish (Oreochromis niloticus) by histological and enzyme histochemical observations and by transmission electron microscopy. Bone resorbing cells (osteoclasts) were identified by their location at the sites of bone resorption, their f...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Witten PE,Bendahmane M,Abou-Haila A

    更新日期:1997-02-01 00:00:00

  • The innervation pattern of crustacean skeletal muscle. Morphometry and ultrastructure of terminals and synapses.

    abstract::The innervation pattern of distal muscle fibers of the opener muscle of walking legs of crayfish (Astacus leptodactylus) was investigated using methylene-blue staining, cobalt infiltration, and electron microscopy. A quantitative analysis of the entire innervation of single muscle fibers was attempted. It was found th...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Florey E,Cahill MA

    更新日期:1982-01-01 00:00:00

  • Uptake and transport of immunoglobulin by the chick choroid plexus. I. Studies with enzyme-treated human immunoglobulin in tissue culture.

    abstract::The choroid plexus from the lateral ventricles of 18-day chick embryos was cultivated as an organ in medium 199 until the degeneration of the stroma. Selected plexuses forming an empty epithelial sac were then incubated with enzyme-treated human immunoglobulin (5S-antibody) and with native human immunoglobulin (7S-ant...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Vollerthun R,Möller W

    更新日期:1980-01-01 00:00:00

  • beta-Adrenergic insulin release and adrenergic innervation of mouse pancreatic islets.

    abstract::An investigation of the stereospecificity of beta-adrenergic insulin release, its relation to alpha-adrenergic blockade and the adrenergic innervation of the pancreatic islets was performed in the mouse. It was observed that in vivo beta-adrenergic stimulation of insulin release by isopropylnoradrenaline was stereospe...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Lundquist I,Ericson LE

    更新日期:1978-10-06 00:00:00

  • Sensory organs of the thoracic legs of the moth Manduca sexta.

    abstract::The thoracic legs of the moth Manduca sexta acquire a new form and develop a new complement of sensory organs and muscles during metamorphosis from larva to adult. Because of our interest in the reorganization of neural circuitry and the acquisition of new behaviors during metamorphosis, we are characterizing sensory ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Kent KS,Griffin LM

    更新日期:1990-02-01 00:00:00

  • FoxO3a suppression and VPS34 activity are essential to anti-atrophic effects of leucine in skeletal muscle.

    abstract::Our aim is to gain insight into the mechanisms underlying the anti-atrophic effects of leucine, namely, the way that this amino acid can restrain the up-regulation of MuRF1 and Mafbx/Atrogin-1 in muscle atrophy. Male rats received dietary leucine supplementation for 1-3 days, during which time their hind limbs were im...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Baptista IL,Silvestre JG,Silva WJ,Labeit S,Moriscot AS

    更新日期:2017-08-01 00:00:00