Abstract：
:Intercellular bridges (IBs) connecting the cytoplasms of a defined type of defective germ cell division ("arrested mitoses") in male and female gonads of the immature golden hamster were studied by electron microscopy. In both sexes, such cells appear at the time when germ cells switch from mitotic proliferation to the onset of meiotic prophase, i.e., during a short perinatal period in the female and during pubertal maturation in the male golden hamster. These cells are arrested and finally degenerate. IBs of these cells completely lack the bridge-partitioning complex (BPC), a structure composed of a stack of transverse endomembrane cisternae which normally fills the IBs during subsequent divisions of bridge-connected germ cells. This unique exception from the usual course of clonal proliferation of mammalian germ cells has several implications: (1) The supposed barrier function of the BPC is missing in the defective germ cell divisions; (2) the failure to form the BPC might be related to a disturbed microtubule apparatus in the cells; (3) the absence of the BPC possibly reflects the influence of conflicting environmental signals, inducing both mitotic and early meiotic mechanisms in the cells at this crucial point of gametogenesis.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Miething Adoi
10.1007/s00441-002-0523-1keywords:
subject
Has Abstractpub_date
2002-04-01 00:00:00pages
103-8issue
1eissn
0302-766Xissn
1432-0878journal_volume
308pub_type
杂志文章abstract：:Prostatic carcinoma affects 1 in 11 men and targets bone with sclerotic metastases. The study of prostate carcinoma growth in bone has been hampered by the lack of suitable animal models. We have developed an in vivo model of prostate carcinoma growth in bone by inoculating three human prostate carcinoma cell lines (P...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-001-0503-x
更新日期：2002-03-01 00:00:00
abstract：:Comparing the distribution of cytoplasmic particles and organelles between different experimental conditions can be challenging due to the heterogeneous nature of cell morphologies. The border-to-border distribution method was created to enable the quantitative analysis of fluorescently labeled cytoplasmic particles a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2265-x
更新日期：2016-02-01 00:00:00
abstract：:Uptake of uteroglobin (UGL) by day-6 rabbit blastocysts and the intracellular fate of this protein were studied by light- and electron-microscopic autoradiography, immunocytochemistry and acid-phosphatase cytochemistry. UGL, labelled with N-succinimidyl-(2-3-3H)-propionate, was administered to embryos in vitro for 25 ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305254
更新日期：1990-12-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217273
更新日期：1982-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00331380
更新日期：1994-12-01 00:00:00
abstract：:Growing numbers of translational genomics studies are based on the highly efficient and versatile zebrafish (Danio rerio) vertebrate model. The increasing types of zebrafish models have improved our understanding of inherited kidney diseases, since they not only display pathophysiological changes but also give us the ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2593-0
更新日期：2017-07-01 00:00:00
abstract：:The three-dimensional ultrastructure of the pineal body of the rat is described on the basis of freeze-fractured preparations. The pineal capsule consists of irregular cells with very flat and perforated processes. Through these openings, extremely branched canaliculi, extending to almost every pineal cell, communicat...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00238052
更新日期：1979-09-02 00:00:00
abstract：:This is the first report on the ultrastructural pattern of distribution of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) in endothelial cells, using the rabbit aorta, and its colocalization with the neuronal isoform (type I) of nitric oxide synthase. About 30% of the endothelial cells showed a posit...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00314551
更新日期：1993-12-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222184
更新日期：1983-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236894
更新日期：1979-08-03 00:00:00
abstract：:Using isoenzyme-specific antisera, we have studied the distribution of protein kinase C isoforms in fetal mouse organs at the developmental age of 17 days. Two different sets of antibodies, produced by different manufacturers, were employed in this study. The specificity of the antisera was tested by immunoblotting ex...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318364
更新日期：1995-06-01 00:00:00
abstract：:Cell degeneration, as a phenomenon accompanying developmental processes, was originally described over a century ago. Apoptosis, a term introduced approximately three decades ago, has occupied investigators particularly with respect to cell and tissue kinetics, emphasizing its role in the disposal of supernumerary, ma...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410000227
更新日期：2000-07-01 00:00:00
abstract：:The motility patterns of the reticulorumen evoke mainly mixing of the ingesta. So far unknown, intrinsic neural circuits of the enteric nervous system are involved in the control of these motility patterns. The aim of the study was to characterize neurochemically sheep ruminal myenteric neurones, in particular the neu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0554-7
更新日期：2002-09-01 00:00:00
abstract：:Fluorescent (aminergic) fibers were demonstrated by the Falck-Hillarp technique in all parts of the neurohypophysis (NH) in the roach (Leuciscus rutilus). The fibers are very thin and few in number in the rostral (RNH) and proximal neurohypophysis (PNH) but slightly more numerous in the NH adjacent to the pars interme...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219959
更新日期：1975-01-01 00:00:00
abstract：:The surface coat of the electrocyte of the main electric organ of Electrophorus electricus was studied using cytochemical methods (periodic acid-silver methanamine, periodic acid-chromic acid-silver methenamine, periodic acid-thiosemicarbazide-silver proteinate, Concanavalin A - horseradish peroxidase, ruthenium red, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226622
更新日期：1977-09-26 00:00:00
abstract：:Autoradiograms of mouse pituitaries were prepared 30 min after injection of 3H-dexamethasone (3HDM), 3H-corticosterone (3HB) and 3H-cortexolone (3HS) either alone or in the presence of competing unlabelled steroids. 3H-dexamethasone accumulated in cell nuclei of both the pars distalis and the pars nervosa but not in t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236423
更新日期：1979-08-01 00:00:00
abstract：:Rainbow trout (Oncorhynchus mykiss) were exposed to ion-poor (soft) water to test the hypothesis that naturally induced proliferation of branchial chloride cells causes a thickening of the blood-to-water diffusion barrier. This was achieved by using a combination of scanning and transmission electron-microscopic techn...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050622
更新日期：1996-07-01 00:00:00
abstract：:With the use of immunocytochemistry, it was shown that both the supraoptic and paraventricular hypothalamic nuclei in humans contain at least two different neurophysins. These two human neurophysins are immunologically related to bovine neurophysin I and neurophysin II, respectively. One human neurophysin is associate...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00240096
更新日期：1979-02-15 00:00:00
abstract：:The Sgcb-null mouse, with knocked-down β-sarcoglycan, develops severe muscular dystrophy as in type 2E human limb girdle muscular dystrophy. The mdx mouse, lacking dystrophin, is the most used model for Duchenne muscular dystrophy (DMD). Unlike DMD, the mdx mouse has mild clinical features and shows little fibrosis in...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-1854-4
更新日期：2014-05-01 00:00:00
abstract：:In adrenalectomized rats the influence of salt loading or salt deprivation on the vasopressin and oxytocin content of the median eminence (ME) and the neural lobe (NL) was studied by means of various methods: morphometric and microphotometric analysis of aldehyde fuchsin-stained sections of ME and NL; immunohistochemi...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/BF00215904
更新日期：1986-01-01 00:00:00
abstract：:The vertebrate limb is a powerful model system for studying the cellular and molecular interactions that determine morphological pattern during embryonic development. Recent advances in our understanding of these interactions have shed new light on the molecular mechanisms of vertebrate limb development, evolution and...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410051261
更新日期：1999-04-01 00:00:00
abstract：:Fibroblast growth factors (Fgfs) are proteins with diverse functions in development, repair, and metabolism. The human Fgf gene family with 22 members can be classified into three groups, canonical, intracellular, and hormone-like Fgf genes. In contrast to canonical and intracellular Fgfs identified in invertebrates a...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-010-1024-2
更新日期：2010-10-01 00:00:00
abstract：:Call-Exner bodies are present in ovarian follicles of a range of species including human and rabbit, and in a range of human ovarian tumors. We have also found structures resembling Call-Exner bodies in bovine preantral and small antral follicles. Hematoxylin and eosin staining of single sections of bovine ovaries has...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051298
更新日期：1999-05-01 00:00:00
abstract：:The distribution and development of growth-associated protein 43 (GAP-43)-like immunoreactivity (-LI) in the rat circumvallate papilla (CVP) were compared to those of protein gene product 9.5 (PGP 9.5)-LI. In the adult, thick GAP-43-like immunoreactive (-IR) structures gathered densely in the subgemmal region. Some of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051142
更新日期：1998-09-01 00:00:00
abstract：:The luminal surface features and junctional complexes from developing blood vessels in the rat central nervous system have been studied by high-voltage electron microscopy and scanning electron microscopy. Developing blood vessels exhibit three types of luminal projections; marginal folds or ridges at junctional compl...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222417
更新日期：1977-01-04 00:00:00
abstract：:Correlations between the presence of surface coat and immobilization antigen of Paramecium tetraurelia were studied. Supravital, partial removal of the surface coat resulted in accelerated response of monobacterially and axenically grown cells to the homologous antiserum. Ciliates pretreated with trypsin or pronase (0...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219984
更新日期：1977-07-11 00:00:00
abstract：:In situ hybridisation and immunohistochemistry analyses have shown that the Ciona intestinalis tumour necrosis factor alpha gene (CiTNFalpha), which has been previously cloned and sequenced, is expressed either during the inflammatory pharynx response to lipopolysaccharide (LPS) or during the swimming larval phase of ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-0993-5
更新日期：2010-08-01 00:00:00
abstract：:Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer's patches contribute to the mucosal immune response by the transcytosis of microorganisms. The mechanism by which M cells take up microorganisms, and the functional proteins by which they do this, are not clear. In order to explore one such prote...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2342-1
更新日期：2016-06-01 00:00:00
abstract：:In the present study, we have analyzed the direct effects of cytokines, which mediate the acute-phase response in liver, on connexin expression and gap-junctional intercellular communication in immortalized MHSV12 mouse hepatocytes. When these cells were stimulated for 24 h with interleukin 1 and interleukin 6, the am...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051184
更新日期：1998-11-01 00:00:00
abstract：:The rejection of skin allografts by the larval lamprey, Lampetra reissneri, was studied by light- and electron-microscopy, with particular attention to the cell types involved in the reaction. In all allografts, melanophores were destroyed within 20-60 days (the mean survival time, 36 +/- 12 days). Neither the epiderm...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222182
更新日期：1983-01-01 00:00:00
