Abstract:
:The localization of neuropeptide Y (NPY) and atrial natriuretic peptide (ANP) in the endothelial cells of human umbilical blood vessels was studied using the pre-embedding peroxidase-antiperoxidase (PAP) technique for electron microscopy and avidin-biotin-complex (ABC) immunostaining for endothelial cells cultured from umbilical vein. Subpopulations of NPY- and ANP-immunoreactive endothelial cells were present in term umbilical vein and artery. The umbilical vein contained more positive cells than the artery. The percentage of NPY- and ANP-immunoreactive umbilical vein cells in culture was 32% and 44%, respectively, out of a total of 3013 cells examined. The possibility that these potent vasoactive substances located in the endothelial cells of the non-innervated umbilical vessels are involved in the local regulation of blood flow is discussed.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Cai WQ,Bodin P,Sexton A,Loesch A,Burnstock Gdoi
10.1007/BF00323584subject
Has Abstractpub_date
1993-04-01 00:00:00pages
175-81issue
1eissn
0302-766Xissn
1432-0878journal_volume
272pub_type
杂志文章abstract::Bullous pemphigoid antigen-1 (BPA1) and alpha(6)beta(4)-integrin colocalize at the hemidesmosomes in basal-layer keratinocytes of normal squamous epithelia. The expression of these genes was analyzed during the process of tumor cell invasion and metastasis on frozen sections of head and neck biopsies, and the structur...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100462
更新日期:2001-12-01 00:00:00
abstract::The present study attempts to elucidate the role of TRPV1 cation channel receptor on primary repair in an incision-wounded mouse cornea in vivo. Previous study revealed that blocking TRPV1 suppressed myofibroblast formation and expression of transforming growth factor β1 (TGFβ1) in cultured keratocytes or ocular fibro...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2878-y
更新日期:2018-11-01 00:00:00
abstract::A somatostatin-like substance is demonstrated by light microscopic immunohistochemistry (PAP-method) in perikarya and cell processes of the retina of adult and infant rats. These perikarya are identified according to their size, arrangement and distribution. Each of the first two neuronal orders (receptors, bipolar ce...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00235169
更新日期:1979-01-01 00:00:00
abstract::By use of the indirect immunofluorescence technique a small group of large somatostatin-positive neurons is described in the subependymal area of the anterior paraventricular thalamus of the male rat. Retrograde-tracing experiments suggest that they project to areas outside the blood-brain barrier. ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215212
更新日期:1986-01-01 00:00:00
abstract::The lymphatic organization and its relationship to the vascular system in the rat small intestine was studied by scanning electron microscopy of corrosion casts and freeze-fractured tissues, and by light microscopy of injected preparations. The villus possessed 3-10 or more central lacteals depending upon the villous ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218204
更新日期:1987-05-01 00:00:00
abstract::Purinergic P2X receptors associated with the parasympathetic nerves supplying human bladder smooth muscle (detrusor) are implicated in control of detrusor contractility. The relative abundance of all seven subtypes colocalised with synaptic vesicles on parasympathetic nerves was examined in specimens from normal adult...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0788-z
更新日期:2003-12-01 00:00:00
abstract::To identify and describe ovarian follicles committed to undergo follicular degeneration (atresia), immature rats were primed with pregnant mare serum gonadotropin (PMSG). After PMSG treatment, preovulatory follicles develop but subsequently degenerate. Prior to the appearance of pyknotic nuclei (Stage I of atresia), d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233727
更新日期:1980-01-01 00:00:00
abstract::The effects, on the maternal mammary gland, of diets containing similar lipid percentages but differing in composition of polyunsaturated fatty acids (PUFA) have been assessed in rats during pregnancy and lactation. For this purpose, tuna fish oil (an n-3-PUFA-enriched oil) and corn oil (an n-6-PUFA-enriched oil) were...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-012-1523-4
更新日期:2013-03-01 00:00:00
abstract::In model experiments with the use of horseradish peroxidase (HRP), two pathways of transport of substances to the adenohypophysis were studied, as well as the distribution of the tracer in the latter organ. The first pathway allows the tracer to penetrate from the intercellular milieu of the median eminence below the ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214248
更新日期:1984-01-01 00:00:00
abstract::Neurons projecting from the brain to the pineal gland via the pineal stalk were investigated in the golden hamster with the use of the retrograde horseradish-peroxidase tracing method both in vivo and in vitro. Labelled perikarya were observed in the medial and lateral habenular nuclei as well as in the posterior comm...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216557
更新日期:1987-01-01 00:00:00
abstract::The structure of the two integumental layers comprising the carapace of female D. magna was examined at several points through the molt cycle. The epicuticle and procuticle are simple in organisation; pore canalsare absent but intracuticular fibres are present, forming complexes with invaginations of the epidermal pla...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214213
更新日期:1976-06-14 00:00:00
abstract::Removal of the somatic DNA methylation pattern from donor cells and remodeling of embryonic status have been suggested as integral processes for successful nuclear transfer (NT) reprogramming. This study has investigated the effects of 5-azacytidine (5-azaC), a DNA methylation inhibitor, on global methylation changes ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-006-0201-9
更新日期:2006-09-01 00:00:00
abstract::Recent advances in the ability to culture the hepatic forms of mammalian malaria parasites, particularly of the important human pathogen Plasmodium falciparum have provided novel opportunities to study the ultrastructural organisation of the parasite in its natural host cell the human hepatocyte. In this electron-micr...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219210
更新日期:1986-01-01 00:00:00
abstract::Central projections of the nervus terminalis (n.t.) in the goldfish were investigated using cobalt- and horseradish peroxidase-tracing techniques. Single n.t. fibers were identified after unilateral application of cobalt chloride-lysine to the rostral olfactory bulb. The central course and branching patterns of indivi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218095
更新日期:1986-01-01 00:00:00
abstract::In the fish retina, connexon densities of gap junctions in the outer horizontal cells are modulated in response to different light or dark adaptation times and wavelengths. We have examined whether the connexon density is a suitable parameter of gap junction coupling under in situ conditions. Short-term light adaptati...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318795
更新日期:1992-05-01 00:00:00
abstract::Back-labeling of regenerated electromotor neurons in the teleost Sternarchus albifrons was performed to test the hypothesis that, in regenerated spinal cord, incorrectly located electromotor neurons are eliminated because their axons do not reach the correct target area (electric organ). In each cross section examined...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217166
更新日期:1985-01-01 00:00:00
abstract::An ultrastructural study of the rostral pars distalis of the pituitary of Aphanius dispar specimens taken from freshwater or hypersaline marshes revealed significant structural differences which indicate higher activity of the prolactin cells in the hypotonic medium. Prolactin cells from freshwater specimens had large...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221103
更新日期:1977-04-20 00:00:00
abstract::S-antigen-immunoreactive pinealocytes located in the deep portion of the pineal organ of inbred and wild pigmented mice give rise to long, beaded processes penetrating into the habenular and pretectal regions. In addition, the medial habenular nuclei and the pretectal area contain S-antigen-immunoreactive perikarya, w...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00313528
更新日期:1990-09-01 00:00:00
abstract::The posterior rhombencephalic tela choroidea of the bullfrog was examined by electron microscopy. This membrane, the pia-ependymal roof of the caudal hindbrain, contains a large central region characterized by cuboidal ependymal cells which surround sizable microscopic apertures -- the interependymal pores. Ultrastruc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220439
更新日期:1979-11-01 00:00:00
abstract::The function of exocytosis during plasma membrane resealing might be to facilitate the flow of surface lipid over the disruption site and/or to add defect-spanning "patches" of internal membrane across it. Scanning-electron-microscopic visualization of large plasma membrane disruptions in sea urchin eggs is here used ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000286
更新日期:2001-04-01 00:00:00
abstract::Aquaporins (AQPs) are integral membrane proteins that function as channels for the transfer of water and small solutes across membranes. In mammalian cells, 13 isoforms (AQP0-12) have been identified, and these exhibit unique patterns of expression in various cell types and tissues. Among these isoforms, AQP6 is consi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0558-4
更新日期:2008-04-01 00:00:00
abstract::Exposure to maternal diabetes during fetal growth is a risk factor for the development of type II diabetes (T2D) in later life. Discovery of the mechanisms involved in this association should provide valuable background for therapeutic treatments. Early embryogenesis involves epigenetic changes including histone modif...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-017-2583-2
更新日期:2017-06-01 00:00:00
abstract::The pituitary gland is first evident in rainbow trout two weeks before hatching. Differentiation of prolactin and ACTH cells is not marked until 3-4 days after hatching when the follicular arrangement of the prolactin cells become apparent. There is no difference in the time of development of either prolactin or ACTH ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00209283
更新日期:1978-05-29 00:00:00
abstract::We have recently identified a tachykinin-related peptide (AmTRP) from the mushroom bodies (MBs) of the brain of the honeybee Apis mellifera L. by using direct matrix-assisted laser desorption/ionization with time-of-flight mass spectometry and have isolated its cDNA. Here, we have examined prepro-AmTRP gene expression...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0865-y
更新日期:2004-05-01 00:00:00
abstract::It is clear that the well-described phenomenon of epithelial-mesenchymal transition (EMT) plays a pivotal role in embryonic development, wound healing, tissue regeneration, organ fibrosis and cancer progression. EMTs have been classified into three subtypes based on the functional consequences and biomarker context in...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-011-1227-1
更新日期:2012-01-01 00:00:00
abstract::Semaphorin 3A (Sema3A) axon repellant serves multiple developmental functions. Sema3A mRNAs are expressed in epithelial and mesenchymal components of the developing incisor in a dynamic manner. Here, we investigate the functions of Sema3A during development of incisors using Sema3A-deficient mice. We analyze histomorp...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1839-3
更新日期:2014-07-01 00:00:00
abstract::During the first postnatal weeks of the developing rodent retina, rhodopsin can be detected in a number of neuron-like cells in the inner retina. In the present study, we aim to characterize the morphology, number and staining characteristics of this peculiar population. Misplaced rhodopsin-positive cells (MRCs) were ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-013-1788-2
更新日期:2014-04-01 00:00:00
abstract::We have developed a simple and reliable method of preserving antigen immunoreactivity with concomitant excellent retention of the cell ultrastructure. Using this method, we have been able to follow the origin and developmental stages of nuage accumulations within the nurse cell/oocyte syncytium in the ovary of the fru...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1145-2
更新日期:2011-04-01 00:00:00
abstract::Ontogenetic development of GRF-containing neurons in the rat hypothalamus was studied employing antisera which were generated against hpGRF (1-44)NH2 and rhGRF(1-43)OH: anti-hpGRF-C and -rhGRF sera recognize the species-specific C-terminal portions of the peptides, and anti-hpGRF-MC and -N sera recognize hpGRF(27-44)N...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00225416
更新日期:1985-01-01 00:00:00
abstract::Mytilus mussels are characterized by annually repeated reproduction which is associated with subsequent growth, morphogenesis, breakdown and redevelopment of the gonad and reproductive tract into mantle mesenchyme. We present a description of the expression of the male-associated polypeptide (MAP; see Mikhailov et al....
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051204
更新日期:1998-12-01 00:00:00