Abstract:
:Back-labeling of regenerated electromotor neurons in the teleost Sternarchus albifrons was performed to test the hypothesis that, in regenerated spinal cord, incorrectly located electromotor neurons are eliminated because their axons do not reach the correct target area (electric organ). In each cross section examined, all of the regenerated electromotor neurons ipsilateral to the implantation site were labeled with horseradish peroxidase, including those ectopic cells located at the edge of the cord, which are later eliminated by selective cell death. Retrograde labeling of these ectopic neurons demonstrates that their axons do extend into the correct target area (the regenerated electric organ). Thus total misdirection of the axons cannot be the cause of their subsequent cell death. We conclude that selective neuronal death in this system does not reflect the absence of axonal projection to the correct target area.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Anderson MJ,Fong HL,Waxman SGdoi
10.1007/BF00217166subject
Has Abstractpub_date
1985-01-01 00:00:00pages
237-40issue
2eissn
0302-766Xissn
1432-0878journal_volume
241pub_type
杂志文章abstract::The size of various tubes within tubular organs such as the lung, vascular system and kidney must be finely tuned for the optimal delivery of gases, nutrients, waste and cells within the entire organism. Aberrant tube sizes lead to devastating human illnesses, such as polycystic kidney disease, fibrocystic breast dise...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-013-1673-z
更新日期:2013-11-01 00:00:00
abstract::Interstitial cells in the pineal gland of the rat were characterized immunocytochemically using the monoclonal antibodies MRC OX-42 and ED1 for macrophages/microglia, and MRC OX-6, which recognizes major histocompatibility complex (MHC) class II antigen. A polyclonal antibody against GFAP was used to identify astrocyt...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00302731
更新日期:1993-05-01 00:00:00
abstract::We report here on cholinergic neurons in the rat hippocampal formation that were identified by immunocytochemistry employing a monoclonal antibody against choline acetyltransferase (ChAT), the acetylcholine-synthesizing enzyme. In general, ChAT-immunoreactive cells were rare, but were observed in all layers of the hip...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215891
更新日期:1986-01-01 00:00:00
abstract::In early postnatal rats, immunoreactive LHRH perikarya in the preoptic area were studied by light and electron microscopy. Synaptic junctions were found between the immunoreactive perikaryon or its process, and the immunonegative nerve fibers. The significance of these synapses is discussed in relation to possible mec...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216754
更新日期:1981-01-01 00:00:00
abstract::This investigation provides histochemical evidence for lysosomal storage of sulfated glycosaminoglycans (GAGs) in the interstitial cells of the renal cortex and in macrophage-like cells of the renal medullary zones of rats chronically treated with the drug tilorone. This compound is known to interfere with lysosomal d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218958
更新日期:1987-12-01 00:00:00
abstract::The distribution of serotonin-immunoreactive cells in the lung of 4 species of reptiles was investigated. Serotonin-containing cells were found forming groups in the interconnecting septa in all 4 species studied, and also as solitary cells in Testudo graeca and Mauremys caspica. Serotonin-containing cells were also l...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216504
更新日期:1987-06-01 00:00:00
abstract::Chronic tissue injury with fibrosis results in the disruption of tissue architecture, organ dysfunction and eventual organ failure. Therefore, the development of effective anti-fibrotic therapies is urgently required. During fibrogenesis, complex interplay occurs between cellular and extracellular matrix components of...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-016-2407-9
更新日期:2016-09-01 00:00:00
abstract::In contrast to the vitellolysis zone which is involved in the degradation of the yolk, the cytoplasmic zone of the yolk syncytial layer, composed of many cytoplasmic organelles, is implicated in a secretory process. The granular endoplasmic reticulum of the latter is extremely well developed and organized into trabecu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236349
更新日期:1979-01-30 00:00:00
abstract::Daily fluctuations of nucleoli and nucleolar fibrillar centres in neurosecretory cells from the supraoptic nucleus (SON) were investigated in rats artificially synchronized for 3 weeks to a set 12 h light/12 h dark cycle with free access to food and water. Group of 3 animals were sacrificed by intracardiac perfusion e...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222351
更新日期:1985-01-01 00:00:00
abstract::The reactivity of rat lymph node macrophages and reticulum cells has been studied in relation to the course of the immune response. Special attention was paid to the interdigitating cells (IDC) in the paracortex and the dendritic reticulum cells (DRC) in the germinal centre. Different types of macrophage predominate i...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00231019
更新日期:1978-08-25 00:00:00
abstract::Elastic cartilage-derived cells cultured two-dimensionally with FGF2 and corticosteroid produce gel-type masses that become mature cartilage when injected into a subcutaneous pocket. This unique method has previously been clinically applied for treatments of nasal augmentation. However, the components of the gel-type ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0438-y
更新日期:2007-09-01 00:00:00
abstract::Steroid hormones intervene in the structural and functional regulation of neuronal processes during development and thus determine brain differentiation. The effects of estrogens are mediated by two transcription factors, namely estrogen receptor α (ER-α) and estrogen receptor β (ER-β), that regulate the expression of...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-2023-5
更新日期:2015-02-01 00:00:00
abstract::The relationship between nitric oxide synthase (NOS)- and galanin-immunoreactive nerve terminals and the origin of NOS-immunoreactive nerve terminals on the motor endplates in the striated muscles of the rat esophagus was investigated. Double immunohistochemical staining revealed a dual innervation of motor endplates ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051230
更新日期:1999-02-01 00:00:00
abstract::Mast cells (MCs) and airway nerves play an important role in allergic asthma. However, little is known about the MCs and their interaction with airway nerves during allergic airway inflammation. This study aims to investigate the distribution and proliferation of MC populations in different lung compartments, along wi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-017-2597-9
更新日期:2017-08-01 00:00:00
abstract::In Syrian hamsters (Mesocricetus auratus), oxytocin (OXT) activity within the medial preoptic-anterior hypothalamus (MPOA-AH) and the ventromedial hypothalamus (VMH) plays an important role in the expression of sexual receptivity. Immunocytochemical analysis with OXT-specific antibodies was used to identify the distri...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050993
更新日期:1998-02-01 00:00:00
abstract::Nervous elements in the periodontal ligament and dental pulp of rat incisors were investigated by means of immunohistochemistry for neurofilament protein (NFP) and glia-specific S-100 protein. The periodontal ligament in the incisors was densely innervated by NFP-immunoreactive nerve fibers; the distribution of the ne...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215442
更新日期:1988-01-01 00:00:00
abstract::Tactile hairs on the locust thorax can be divided into two classes by their external morphology and their central projection pattern: Short hairs, 10--100 micrometer in length, which are assembled in distinct plates and rows, and long hairs, 100--800 micrometer in length, which are distributed all over the body and ar...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234546
更新日期:1981-01-01 00:00:00
abstract::Pancreatic acinar cells of euthermic, hibernating and arousing individuals of the hazel dormouse Muscardinus avellanarius (Gliridae) have been observed at the electron-microscopic level and analysed by means of ultrastructural morphometry and immunocytochemistry in order to investigate possible fine structural changes...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051082
更新日期:1998-06-01 00:00:00
abstract::Germ cells are set aside from somatic cells early in embryogenesis, and are responsible for transmitting genetic information through generations. Vasa is a highly conserved germ cell marker across animal phyla, and widely used to label primordial germ cells. Dabry's sturgeon is a rare and endangered species distribute...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2418-6
更新日期:2016-10-01 00:00:00
abstract::Electron-microscopic studies of lymphoid tissues from bovine fetuses and from calves disclosed a non-lymphoid cell type in the thymus-dependent zones of secondary lymphoid tissues and in the thymus that is distinguishable from reticulum cells, epithelial and endothelial cells, and macrophages. Based on morphological a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213735
更新日期:1984-01-01 00:00:00
abstract::A quantitative evaluation of putative amino acid neurotransmitters in sea pansy polyps by high-performance liquid chromatography indicates that the taurine content exceeds that of other amino acids by a 100-fold. The cellular source of this taurine was investigated by immunohistochemistry with two polyclonal antisera ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050800
更新日期:1997-04-01 00:00:00
abstract::With the use of tissue prepared by freeze-substitution and the unlabelled antibody enzyme technique, neurophysin and vasopressin were localized at the ultrastructural level in the pofterior pituitary and median eminence of the guinea pig. In the posterior pituitary neurophysin was found in the large neurosecretory gra...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221777
更新日期:1975-06-13 00:00:00
abstract::In three species of teleosts - carp Cyprinus carpio; grass carp Ctenopharyngodon idella; and crucian carp Carassius auratus - the caudal neurosecretory system displays small, medium-sized and large neurons. Urotensin I (UI)-immunoreactive and UI-nonreactive neurons were found in all three groups; in general, the numbe...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00212550
更新日期:1986-01-01 00:00:00
abstract::The vascularization of the hypothalamo-adenohypophysial region of the toad Bufo bufo (L.) (Amphibia, Anura) was studied by means of light- and scanning electron microscopy. Special attention was given to the portal vascular system of the median eminence and the pars distalis. Course and arrangement of these vessels ar...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223268
更新日期:1975-09-16 00:00:00
abstract::The development of neurophysin-oxytocin and neurophysin-vasopressin containing neurons of the guinea pig was studied in vitro. Supraoptic (SO) and paraventricular (PV) nuclei were explanted from guinea pig foetuses at the 40th day of gestation and cultured in Maximov slides for nearly fifty days. The cultures were obs...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233269
更新日期:1979-01-01 00:00:00
abstract::The reduced-folate carrier (Rfc-1), previously also called methotrexate carrier-1 (MTX-1), was recently identified as accounting for approximately 30% of the methotrexate (Mtx) uptake into rat kidney slices. The localization of the carrier and its contribution to secretory or reabsorptive flux of the drug was therefor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-1092-x
更新日期:2005-06-01 00:00:00
abstract::Previous studies have indicated that 19-day-old fetal long bones of the rat contain an adenylyl cyclase-stimulating activity antigenically related to parathyroid hormone-related peptide. To ascertain its origin, Northern blotting and in situ hybridization histochemistry were performed. Results demonstrate that mRNA of...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00645063
更新日期:1992-12-01 00:00:00
abstract::The chemical nature of the thickened plasma membrane of cornified cells in stratified squamous epithelium was investigated in comparison with that in noncornified epithelium. Localizations of transglutaminase, molecular weight 92,000 daltons, and detection of epidermal cysteine proteinase inhibitor were effected with ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215516
更新日期:1987-08-01 00:00:00
abstract::In the fish retina, connexon densities of gap junctions in the outer horizontal cells are modulated in response to different light or dark adaptation times and wavelengths. We have examined whether the connexon density is a suitable parameter of gap junction coupling under in situ conditions. Short-term light adaptati...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318795
更新日期:1992-05-01 00:00:00
abstract::Surface features of the ependymal linings of the fourth ventricle in the fowl were analyzed employing the scanning electron microscope (SEM). On the floor of the median sulcus, each ependymal cell has a solitary cilium, whereas on both sides of the sulcus, cilia are so densely distributed that the details of the under...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233562
更新日期:1979-03-09 00:00:00