Oxytocin immunoreactivity in the hypothalamus of female hamsters.

Abstract:

:In Syrian hamsters (Mesocricetus auratus), oxytocin (OXT) activity within the medial preoptic-anterior hypothalamus (MPOA-AH) and the ventromedial hypothalamus (VMH) plays an important role in the expression of sexual receptivity. Immunocytochemical analysis with OXT-specific antibodies was used to identify the distribution of OXT-containing cell bodies and fibers in female hamster brain and to determine the possible sources of OXT important for sexual receptivity. Oxytocin-immunoreactive cell bodies and fibers were found in several regions of the preoptic area, including the medial preoptic area, the medial preoptic nucleus, and the bed nucleus of the stria terminalis. Large numbers of cell bodies and fibers were localized within the paraventricular and supraoptic nuclei, and in anterior hypothalamus. OXT-immunoreactive fibers were observed in the VMH and the ventral tegmental area. The anatomical data from the present study support the hypothesis that OXT activity in the MPOA-AH and the VMH plays an important role in the regulation of sexual receptivity in hamsters.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Whitman DC,Albers HE

doi

10.1007/s004410050993

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

231-7

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

291

pub_type

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