Abstract：
:Iron loading of hepatocytes was followed through the stages (1-7) of metamorphosis in lamprey (Petromyzon marinus L.) using light- and electron-microscopic histochemistry. Iron is present in ferric and ferrous forms in the hepatocytes of larval lampreys in levels that can only be detected in the electron microscope. During the initial stages (1-3) of metamorphosis iron begins to increase in the cytoplasmic matrix and in dense bodies but it is not apparent in the light microscope until stage 4. The increased accumulation of iron through the subsequent stages (5-7) of metamorphosis coincides with the advanced degeneration and ultimate disappearance of bile canaliculi and bile ducts. The absence of a bile canaliculus is concurrent with the beginning of staining of lateral cell borders for ferrous iron and with intense concentrations of ferric iron throughout the cytoplasmic matrix and within cytoplasmic dense bodies. By the end of metamorphosis the hepatocytes resemble iron-loaded hepatocytes in pathological and experimentally induced situations in other vertebrates. The iron loading of hepatocytes during metamorphosis is discussed with respect to both the concomitant atresia of the biliary tree and alteration of several aspects of blood morphology and chemistry. Since iron loading occurs synchronously in the hepatocytes of a given population of metamorphosing lampreys, this organism should prove to be a useful experimental system for investigation on cellular mechanisms of iron loading in vertebrates.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Youson JH,Sargent PA,Sidon EWdoi
10.1007/BF00217405subject
Has Abstractpub_date
1983-01-01 00:00:00pages
109-24issue
1eissn
0302-766Xissn
1432-0878journal_volume
234pub_type
杂志文章abstract：:We used a combined biochemical and histocytochemical approach to study ecto-ATPase in the rat cardiac muscle. The reaction medium employed for histocytochemical detection was optimized in biochemical assays to achieve the highest enzyme activity and lowest inhibition by the capture agent used for visualization of the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900105
更新日期：1999-12-01 00:00:00
abstract：:The expression of corticosteroids and regional expression 16 (CR16) and neural Wiscott-Aldrich syndrome protein (N-WASP) was studied in the testes of men with idiopathic azoospermia by (1) immunohistochemistry and Western blot to detect the expression of CR16 and N-WASP protein, (2) reverse transcription with the poly...
journal_title：Cell and tissue research
pub_type： 杂志文章
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更新日期：2011-06-01 00:00:00
abstract：:Mesenchymal stem cells (MSCs) are increasingly being reported as occurring in a variety of tissues. Although MSCs from human bone marrow are relatively easy to harvest, the isolation of rodent MSCs is more difficult, thereby limiting the number of experiments in vivo. To determine a suitable cell source, we isolated r...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0308-z
更新日期：2007-03-01 00:00:00
abstract：:Call-Exner bodies are present in ovarian follicles of a range of species including human and rabbit, and in a range of human ovarian tumors. We have also found structures resembling Call-Exner bodies in bovine preantral and small antral follicles. Hematoxylin and eosin staining of single sections of bovine ovaries has...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051298
更新日期：1999-05-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0282-5
更新日期：2007-01-01 00:00:00
abstract：:Histological, histochemical, and electron microscopical investigations of the rat pancreas, one to five hours after pilocarpine injection (4 mg in 1 ml normal saline solution), showed different secretory responses in periinsular and apoinsular acinar cells. The responsiveness to parasympathetic stimulation is markedly...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222119
更新日期：1975-08-01 00:00:00
abstract：:In Nassarius reticulatus the nuclei and nucleoli undergo important morphological changes from the zygote to the 16-cell stage. In the zygote and in the trefoil (2-cell) and 4-cell stage, several agranular, fibrillar nucleolus-like bodies 1 mum diameter are present in the interphase nucleus. Granular nucleoli first app...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215313
更新日期：1976-05-13 00:00:00
abstract：:The molecular cloning of a cDNA fragment synthesised from rat duodenal mRNA coding for cholecalcin (calbindin), a 9000 Mr vitamin D-induced calcium-binding protein (CaBP), has been previously described. DNA/RNA hybridisation assays have been used to examine CaBP mRNA production in the uterine horns and duodena of preg...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216546
更新日期：1987-01-01 00:00:00
abstract：:Rat quiescin/sulphydryl oxidase (rQSOX) introduces disulphide bridges into peptides and proteins with the reduction of molecular oxygen to hydrogen peroxide. Its occurrence has been previously highlighted in a wide range of organs by reverse transcription-polymerase chain reaction (RT-PCR) and Northern blot analyses, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0043-x
更新日期：2006-01-01 00:00:00
abstract：:The surface coat of the electrocyte of the main electric organ of Electrophorus electricus was studied using cytochemical methods (periodic acid-silver methanamine, periodic acid-chromic acid-silver methenamine, periodic acid-thiosemicarbazide-silver proteinate, Concanavalin A - horseradish peroxidase, ruthenium red, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226622
更新日期：1977-09-26 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220825
更新日期：1976-11-24 00:00:00
abstract：:Normal development, function and repair of the sensory epithelia in the inner ear are all dependent on gap junctional intercellular communication. Mutations in the connexin genes GJB2 and GJB6 (encoding CX26 and CX30) result in syndromic and non-syndromic deafness via various mechanisms. Clinical vestibular defects, h...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-2029-z
更新日期：2015-06-01 00:00:00
abstract：:The startle is a relatively simple ubiquitous reflex. Interestingly, it has a "non-zero baseline", i.e., its magnitude can be reduced or enhanced. We reflect here on the translational value of prepulse inhibition and fear-related potentiation as endophenotypes that can be used for the investigation of complex psychiat...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-013-1599-5
更新日期：2013-10-01 00:00:00
abstract：:Bone marrow (BM) from human and rodent species contains a population of multipotential cells referred to as mesenchymal stem cells (MSCs). Currently, MSCs are isolated indirectly by using a culture step and then the generation of fibroblast colony-forming units (CFU-fs). Unprocessed or native BM MSCs have not yet been...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0292-3
更新日期：2007-03-01 00:00:00
abstract：:Apoptotic and inflammatory processes occur in human arteriosclerotic lesions. We examined the hypothesis whether both processes are possibly associated by studying the colocalization of corresponding markers. In 11 human arteriosclerotic carotid arteries, proapoptotic markers (CPP32 (caspase-3), poly(ADP-ribose) polym...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0024-0
更新日期：2005-12-01 00:00:00
abstract：:Granular hormone-producing cells and agranular cells (stellate cells, including giant and pericavitary cells) were electron microscopically studied in the hypophysis of the small spotted dogfish (Scyllium canicula) up to several months after hatching. Comparisons of results obtained in embryos, newly-hatched fish and ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221607
更新日期：1978-10-06 00:00:00
abstract：:An attempt has been made to reveal which of the nine different types of synapses in the fundus striati, discriminated in a previous study, degenerate following experimental lesions in the parafasciculo-center median complex of the cat. Two types of synaptic contacts were found to be degenerated two days after the lesi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226045
更新日期：1976-09-06 00:00:00
abstract：:In model experiments with the use of horseradish peroxidase (HRP), two pathways of transport of substances to the adenohypophysis were studied, as well as the distribution of the tracer in the latter organ. The first pathway allows the tracer to penetrate from the intercellular milieu of the median eminence below the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214248
更新日期：1984-01-01 00:00:00
abstract：:The effect of copulation on the rat coagulating gland (anterior prostate) was studied. At 4 to 6 h after the beginning of copulation the coagulating glands of rats that had produced copulatory plugs were nearly empty of secretion. Ultrastructurally, the coagulating gland has large cisternae of rough endoplasmic reticu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221773
更新日期：1977-07-19 00:00:00
abstract：:A study of the organisation of the locust dorsal ocellus shows that the structure is designed to provide the maximum possible effective aperture. The condenser-like cuticular lens and the dispersal of the rhabdome over a large proportion of the circumferential area of the retinula cells increases the light gathering p...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234742
更新日期：1979-02-28 00:00:00
abstract：:Ornithine decarboxylase (ODC) activity was measured in homogenates of neonatal rabbit ovaries from the day of birth to day 22, an interval that corresponds to the progressing stages of the meiotic prophase from oogonia to diplotene and follicle formation. The ODC-activity was high on days 1 and 3 when most germ cells ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218114
更新日期：1983-01-01 00:00:00
abstract：:Nucleoside di-phosphate kinase enzyme (NDPK) isoforms, encoded by the nm23 family of genes, may be involved in various cellular differentiation and proliferation processes. We have therefore analyzed the expression of nm23-M1, -M2, -M3, and -M4 during embryonic mouse development. In situ hybridization data has reveale...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0036-9
更新日期：2005-12-01 00:00:00
abstract：:This study describes the morphology and distribution of setae on the lateral and medial flagella of the antennules of the spiny lobster Panulirus argus in an effort to identify antennular chemoreceptors in addition to the well-studied aesthetasc chemosensilla. Setae were examined using light and electron microscopy, a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410100377
更新日期：2001-06-01 00:00:00
abstract：:This review summarizes findings concerning the unique developmental characteristics of mouse head muscles (mainly the masticatory and tongue muscles) and compares their characteristics with those of other muscles. The developmental origin of the masticatory muscles is the somitomeres, whereas the tongue and other musc...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-005-0019-x
更新日期：2005-11-01 00:00:00
abstract：:During the first postnatal weeks of the developing rodent retina, rhodopsin can be detected in a number of neuron-like cells in the inner retina. In the present study, we aim to characterize the morphology, number and staining characteristics of this peculiar population. Misplaced rhodopsin-positive cells (MRCs) were ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1788-2
更新日期：2014-04-01 00:00:00
abstract：:An indirect immunofluorescence study of the frozen sections of the spleen of an anuran amphibian, Xenopus laevis, showed that lymphocytes bearing a small amount of immunoglobulin (Ig) were localized mostly in the white pulp of non-immunized toads. There were fewer fluorescent cells in the red pulp. In the toads hyperi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218363
更新日期：1982-01-01 00:00:00
abstract：:Desmin is a muscle-specific type III intermediate filament essential for proper muscular structure and function. In human, mutations affecting desmin expression or promoting its aggregation lead to skeletal (desmin-related myopathies), or cardiac (desmin-related cardiomyopathy) phenotypes, or both. Patient muscles dis...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-2016-4
更新日期：2015-06-01 00:00:00
abstract：:Trichoplax, a member of the phylum Placozoa, is a tiny ciliated marine animal that glides on surfaces feeding on algae and cyanobacteria. It stands out from other animals in that it lacks an internal digestive system and, instead, digests food trapped under its lower surface. Here we review recent work on the phenotyp...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-019-03057-z
更新日期：2019-09-01 00:00:00
abstract：:The distribution and chemical neuroanatomy of nervous elements and certain pharmacological-physiological characteristics of the innervation of the body wall in earthworms are described. Solitary sensory bipolar cells can be found among the epithelial cells. These bipolar cells contain serotonin, tyrosine hydroxylase, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1134-4
更新日期：2005-09-01 00:00:00
abstract：:In the present study, the effect of LHRH on the process of protein and/or peptide secretion characterized by the formation of granular vesicles has been studied by means of an in vitro system in the pinealocytes of three different species of rodents. LHRH has a strong influence on the activity of this process. However...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216426
更新日期：1983-01-01 00:00:00
