Abstract：
:The orderly arrangement of fibroblasts and collagen in tendons and ligaments suggests that these cells may have precise relationships with one another and with the collagen fibrils. The spatial organization of rat tail tendon was therefore examined using scanning and transmission electron microscopy and by reconstructing a 35-microns long segment of tendon from serial transmission electron micrographs. Fibroblasts were regularly arranged in columns and showed more intimate association in the longitudinal than in the transverse plane. Thin cytoplasmic sheets extended up to 3 microns transversely, frequently forming junctional attachments with similar processes from adjacent cells or from the same cell. Longitudinal processes were longer, often extending for more than 20 microns and forming junctional attachments with other cells in the same column. Such processes often exhibited invaginations in which there were single fibrils or small groups of fibrils; this arrangement may be indicative of fibril elongation or may serve to transmit tension between the fibroblast and the collagen fibrils. This organization has interesting implications for the growth and function of other fibrous connective tissue, such as the periodontal ligament.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Squier CA,Bausch WHdoi
10.1007/BF00217304subject
Has Abstractpub_date
1984-01-01 00:00:00pages
319-27issue
2eissn
0302-766Xissn
1432-0878journal_volume
238pub_type
杂志文章abstract：:The accessory medulla with its associated pigment-dispersing hormone-immunoreactive neurons appears to be the pacemaker that controls the circadian locomotor activity rhythm of the cockroach Leucophaea maderae. To permit studies at the level of individual, identified, pacemaker neurons, we developed specific long-term...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051324
更新日期：1999-06-01 00:00:00
abstract：:The LIM homeodomain transcription factor Lmx1a shows a dynamic expression in the developing mouse ear that stabilizes in the non-sensory epithelium. Previous work showed that Lmx1a functional null mutants have an additional sensory hair cell patch in the posterior wall of a cochlear duct and have a mix of vestibular a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03163-y
更新日期：2020-06-01 00:00:00
abstract：:Osteoblasts are specialized mesenchyme-derived cells accountable for bone synthesis, remodelling and healing. Differentiation of osteoblasts from mesenchymal stem cells (MSC) towards osteocytes is a multi-step process strictly controlled by various genes, transcription factors and signalling proteins. The aim of this ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-013-1750-3
更新日期：2014-01-01 00:00:00
abstract：:Although the secretory products of the hypothalamo-neurohypophyseal system are not glycoproteins, synthesis and migration of these macromolecules occur within its secretory neurons. After being labeled with 3H-fucose in the Golgi apparatus, newly synthesized glycoproteins migrate to secretion granules, lysosomes and t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234755
更新日期：1980-01-01 00:00:00
abstract：:The adrenal gland of mammals contains high concentrations of peripheral-type benzodiazepine receptors (PBR) and diazepam-binding inhibitor (DBI), a polypeptide which acts as an endogenous ligand for PBR. The aim of the present study was to investigate the localization of DBI and PBR in the adrenal gland of the frog Ra...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050551
更新日期：1996-03-01 00:00:00
abstract：:Structures identified as subsurface cisterns (SSC's) were found in neurons of the paraventricular nuclei of the rat hypothalamus. They appeared as cytoplasmic organelles consisting most often of stacks of parallel cisterns apposed to the neuronal plasmalemma. These SSC's were located in the interneurons of the parvoce...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236138
更新日期：1979-06-27 00:00:00
abstract：:Unique rod-shaped secretory granules were observed among oval or spherical secretory granules in GH cells of the anterior pituitary gland of musk shrew using the protein A-gold procedure combined with electron microscopy. The rod-shaped and spherical secretory granules were both immunoreactive by the immuno-gold metho...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215454
更新日期：1988-01-01 00:00:00
abstract：:Male rats kept on a standard diet were treated either with progesterone or testosterone by a single intramuscular injection of preparations which are slowly absorbed and metabolized. The rats were anaesthetized 24 h after application of the hormones, perfused with glutaraldehyde, and the parathyroid glands prepared fo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318797
更新日期：1992-05-01 00:00:00
abstract：:The cellular localization of the enzymes tyrosine hydroxylase (TH), aromatic amino-acid decarboxylase (or dopa decarboxylase, DDC), dopamine beta-hydroxylase (DBH) and phenylethanolamine N-methyltransferase (PNMT) in the adrenal medulla of adult rats and rat fetuses (14th, 17th, 18th, 19th and 21st day) was examined. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236882
更新日期：1979-08-03 00:00:00
abstract：:We describe the histological basis of color metamorphosis in the polychromatic Midas cichlid, Cichlasoma citrinellum. Eight percent of the individuals in a natural population transform from gray with black markings to orange, simultaneously losing their ability to adjust coloration in response to background and social...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221733
更新日期：1988-07-01 00:00:00
abstract：:Intercellular bridges (IBs) connecting the cytoplasms of a defined type of defective germ cell division ("arrested mitoses") in male and female gonads of the immature golden hamster were studied by electron microscopy. In both sexes, such cells appear at the time when germ cells switch from mitotic proliferation to th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0523-1
更新日期：2002-04-01 00:00:00
abstract：:To further evaluate the role of autonomic ganglia in the regulation of pelvic visceral activity, the neural elements in the major pelvic ganglion of the male rat have been studied with histochemixal and electron microscopic techniques. The principal findings are that the ganglion is composed of cholinergic and adrener...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231994
更新日期：1975-05-27 00:00:00
abstract：:The effects of cytochalasin B (CB) on pancreatic structure and amylase release were studied by use of pancreatic fragments, isolated acini and isolated acinar cells. In pancreatic fragments and isolated acini CB caused the disappearance of microfilaments underlying the apical plasma membrane, loss of apical microvilli...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219848
更新日期：1977-04-29 00:00:00
abstract：:This report demonstrates that the administration of testosterone (T) or 11-ketotestosterone (11-KT) to sexually immature (8 wks old) male platyfish (Xiphophorus maculatus) of early- and late-maturing genotypes affects the synthesis and/or release of luteinizing hormone-releasing hormone (LHRH), as assessed by immunocy...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218552
更新日期：1986-01-01 00:00:00
abstract：:The immunocytochemical localization of bovine oviduct-specific glycoproteins was investigated by light and electron microscopy. Using monoclonal antibodies (MAbs) specific for bovine oviductal glycoproteins, 3 regions (fimbriae, ampulla, and isthmus) of the epithelium in the bovine oviduct we studied during the follic...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00327983
更新日期：1993-10-01 00:00:00
abstract：:A culture technique for the in vitro growth and differentiation of antennal cells of Mamestra brassicae is described. The morphology of the growing cells is described. At least five morphological cell types can be distinguished in the cultures. Neuronal cells (type A) were characterized morphologically and immunocytoc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050884
更新日期：1997-08-01 00:00:00
abstract：:An antiserum against conjugated histamine and two oligonucleotide probes that detect the mRNA encoding L-histidine decarboxylase (HDC) involved in histamine synthesis were used to study the appearance of histamine and its location in the kidneys of fetal, newborn and young postnatal rats and in the kidneys of pregnant...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00302960
更新日期：1992-02-01 00:00:00
abstract：:We have recently identified a tachykinin-related peptide (AmTRP) from the mushroom bodies (MBs) of the brain of the honeybee Apis mellifera L. by using direct matrix-assisted laser desorption/ionization with time-of-flight mass spectometry and have isolated its cDNA. Here, we have examined prepro-AmTRP gene expression...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0865-y
更新日期：2004-05-01 00:00:00
abstract：:The dorsal root ganglion (DRG) and dorsal horn of the spinal cord are areas through which primary afferent information passes enroute to the brain. Previous studies have reported that, during normal neuronal activity, the regional distribution of a second messenger, diacylglycerol (DG), which is derived from phosphoin...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0219-z
更新日期：2006-10-01 00:00:00
abstract：:A recently developed immunohistochemical technique for serotonin (Steinbusch et al. 1978) was used in the present investigation to study the occurrence of this indoleamine in the granulated epithelial cells of neuro-epithelial bodies (NEB). Lungs from neonatal rabbits and pigs exhibit immunoreactive cell groups identi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217095
更新日期：1982-01-01 00:00:00
abstract：:Dorsal unpaired median (DUM) neurones in the abdominal ganglia of the locust were impaled with microelectrodes and some were injected intracellularly with horseradish peroxidase so that their synapses could be identified in the electron microscope. Simultaneous recordings from DUM neurones in different abdominal gangl...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00307805
更新日期：1995-05-01 00:00:00
abstract：:Over the past decade, adult stem cells have attracted great attention because of their ability to potentially regenerate desired tissues or entire organs. With the emergence of nanomaterial-based gene therapy, adult stem cells have been considered as a proper tool for the biomedical field. In this study, we utilized o...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2235-3
更新日期：2015-12-01 00:00:00
abstract：:Neurofilaments, which are exclusively found in nerve cells, are one of the earliest recognizable features of the maturing nervous system. The differential distribution of neurofilament proteins in varying degrees of phosphorylation within a neuron provides the possibility of selectively demonstrating either somata and...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051013
更新日期：1998-03-01 00:00:00
abstract：:The periodontal ligament (PDL) is a highly specialized tissue connecting the cementum with the tooth socket bone and affects the life span of the tooth. However, little is known about the precise characteristics and regenerative mechanism of PDL cells because of the absence of specific markers and cell lines. Therefor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0101-4
更新日期：2006-04-01 00:00:00
abstract：:The expression of corticosteroids and regional expression 16 (CR16) and neural Wiscott-Aldrich syndrome protein (N-WASP) was studied in the testes of men with idiopathic azoospermia by (1) immunohistochemistry and Western blot to detect the expression of CR16 and N-WASP protein, (2) reverse transcription with the poly...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1159-9
更新日期：2011-06-01 00:00:00
abstract：:In the developing mammalian nervous system, common progenitors integrate both cell extrinsic and intrinsic regulatory programs to produce distinct neuronal and glial cell types as development proceeds. This spatiotemporal restriction of neural progenitor differentiation is enforced, in part, by the dynamic reorganizat...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-2011-9
更新日期：2015-01-01 00:00:00
abstract：:The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that have been implicated in both receptor and store-operated channel functions. The family of the classical TRPs (TRPCs) consists of seven members (TRPC1-7). The presence of TRPC1 and TRPC5 mRNA in the brain has prev...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0004-4
更新日期：2005-11-01 00:00:00
abstract：:The H-Tx rat has fetal-onset hydrocephalus associated with closure of the cerebral aqueduct and a reduction in the secretory cells of the subcommissural organ (SCO), a circumventricular organ situated in the dorsal wall of the cerebral aqueduct. The objective of this study was to determine the role of the SCO in hydro...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0843-9
更新日期：2004-03-01 00:00:00
abstract：:The prothoracicotropic hormone (PTTH), which stimulates ecdysteroid synthesis in the prothoracic glands, is produced, in the dorso-lateral protocerebrum of Manduca sexta, by paired peptidergic neurons, the lateral neurosecretory cell group III (L-NSC III). Our study revealed ultrastructural features of L-NSC III, iden...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00303082
更新日期：1994-07-01 00:00:00
abstract：:The distribution of VIP-like perikarya and fibers was determined throughout the chick brain. The most rostral immunoreactive perikarya were found to be cerebrospinal fluid-contacting neurons in the pars medialis of the lateral septal organ. Additional data were presented supporting the idea that the lateral septal org...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305378
更新日期：1994-01-01 00:00:00
