Abstract:
:This report demonstrates that the administration of testosterone (T) or 11-ketotestosterone (11-KT) to sexually immature (8 wks old) male platyfish (Xiphophorus maculatus) of early- and late-maturing genotypes affects the synthesis and/or release of luteinizing hormone-releasing hormone (LHRH), as assessed by immunocytochemical evaluation, increases the number and activity of pituitary gonadotropes, stimulates the production of sperm and, thus, advances the age of sexual maturation over that dictated by the genome. We also show that 11-KT and T affect different LHRH-containing centers in the brain and have differential effects on rate and degree of sexual maturation, regardless of whether the hormones are administered to early or late-maturing genotypes.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Schreibman MP,Margolis-Nunno H,Halpern-Sebold LR,Goos HJ,Perlman PWdoi
10.1007/BF00218552subject
Has Abstractpub_date
1986-01-01 00:00:00pages
519-24issue
3eissn
0302-766Xissn
1432-0878journal_volume
245pub_type
杂志文章abstract::Right superior cervical sympathectomy was performed in one-day old rats. This operation had a small but definite effect on the postnatal development of the submandibular gland. The gland on the sympathectomized side weighed less and contained smaller amounts of DNA, RNA and protein than the contralateral intact gland....
journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章
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