Abstract：
:Ontogenetic development of GRF-containing neurons in the rat hypothalamus was studied employing antisera which were generated against hpGRF (1-44)NH2 and rhGRF(1-43)OH: anti-hpGRF-C and -rhGRF sera recognize the species-specific C-terminal portions of the peptides, and anti-hpGRF-MC and -N sera recognize hpGRF(27-44)NH2 and the N-terminal portion of hpGRF(1-44)NH2, respectively. The anti-hpGRF-C and -rhGRF sera stained different neuronal cell bodies, which were localized in distinct hypothalamic areas. The former serum did not stain the axonal terminals in the median eminence, but the latter stained them strongly. The anti-hpGRF-MC and -N sera stained neuronal cell bodies, some of which corresponded to those immunolabelled with anti-hpGRF-C or -rhGRF serum. The anti-rhGRF serum first demonstrated immunoreactive perikarya in the ventral-lateral border of the arcuate nucleus of 19.5-day-old fetuses that had received an intraventricular colchicine administration 24 h previously. The immunoreactive fibers were recognized first in the external layer of the median eminence of untreated fetuses on day 19.5 of gestation, and then they increased in amount with development. No immunoreactive fibers, however, were found in the median eminence of colchicine-treated animals during the fetal period. It is concluded that in rats GRF may be synthesized in the perikarya on day 18.5 of gestation and conveyed to the median eminence without delay via axonal flow.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Daikoku S,Kawano H,Noguchi M,Tokuzen M,Chihara K,Saito H,Shibasaki Tdoi
10.1007/BF00225416subject
Has Abstractpub_date
1985-01-01 00:00:00pages
511-8issue
3eissn
0302-766Xissn
1432-0878journal_volume
242pub_type
杂志文章abstract：:In recent years, data have accumulated suggesting that the role of neurotrophins and Trk receptors may not be limited to the nervous system, and the presence of these substances has been detected in a variety of vertebrate and invertebrate non-nervous tissues. This study was designed to map the expression of immunorea...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000181
更新日期：2000-04-01 00:00:00
abstract：:The axon hillock (AH) and initial segment (IS) of 10 Golgi neurons and 6 basket cells in the cerebellar cortex of the rat were investigated by electron microscopy using serial sections. An average of 10.4 and 11.3 synaptic terminals were observed to establish synaptic contact with the axon hillock region of Golgi and ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219363
更新日期：1981-01-01 00:00:00
abstract：:The pineal organ of the eel, Anguilla anguilla was studied light-and electron-microscopically. The tissue consists predominantly of glia-like supporting cells and photoreceptor-like sensory cells, which establish synaptic contacts with pineal nerve cells. Histochemically, a positive acetylcholinesterase (AchE) reactio...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00238650
更新日期：1981-01-01 00:00:00
abstract：:With the gallocyanine technique (Wittkowski, Bock and Franken, 1970) Gomori-positive substances of the infundibulum can be stained for light- and electron-microscopic examination. In various mammalian species, the size of Gomori-positive elementary granules in the outer layer is markedly different from that in the inn...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218495
更新日期：1975-11-19 00:00:00
abstract：:NCS-1 (neuronal calcium sensor) is a recently characterized member of a highly conserved neuron-specific family of calcium-binding proteins, which also includes frequenin and recoverin. The cellular and subcellular distributions of NCS-1 in the rat nervous system were investigated using light- and electron-microscopic...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051246
更新日期：1999-03-01 00:00:00
abstract：:Aromatase, the enzyme converting androgens into estrogens, is involved in many brain processes such as neural differentiation and plasticity or the prevention of cell death. We have previously observed an increase in aromatase immunoreactivity in sheep neurons exposed in vitro to the oxidant 3-nitro-L: -tyrosine. Howe...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1160-3
更新日期：2011-06-01 00:00:00
abstract：:Using histochemical, immunohistochemical and biochemical techniques, noradrenaline-, neuropeptide Y-, vasoactive intestinal polypeptide-, substance P- and calcitonin gene-related peptide-containing nerve fibres were studied in the uterine artery of virgin, progesterone-treated and pregnant guinea-pigs. Morphological c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF01740777
更新日期：1990-03-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233891
更新日期：1978-12-29 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2487-6
更新日期：2016-12-01 00:00:00
abstract：:The distribution and structure of the ureteric nerves in a small series of mammals was compared with that previously demonstrated in the rat. There was marked interspecies variation in the extent to which the nerves penetrated the wall of the ureter and in the degree of development of the deep submucous plexus. In ani...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00225768
更新日期：1975-07-23 00:00:00
abstract：:The gene encoding H1t, a testicular variant of histone H1, is expressed in mammals during spermatogenesis. Northern blot and in situ hybridization has detected H1t mRNA only at the stage of pachytene spermatocytes. We have extended this analysis to more sensitive approaches and demonstrate, by RNase protection and ele...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050986
更新日期：1998-01-01 00:00:00
abstract：:Osteogenic differentiation is a tightly regulated process realized by progenitor cell osteoblasts. Notch signaling pathway plays a critical role in skeletal development and bone remodeling. Controversial data exist regarding the role of Notch activation in promoting or preventing osteogenic differentiation. This study...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03130-7
更新日期：2020-01-01 00:00:00
abstract：:Marked changes in mice pubic symphysis occur by the end of pregnancy. Tissue remodeling involves a dynamic balance between cell proliferation and programmed cell death as well as changes in the extracellular matrix components. Therefore, it is important to consider both of these cellular behaviors when investigating t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0463-x
更新日期：2007-10-01 00:00:00
abstract：:Horse spleen ferritin, injected into the blood of the octopus, leaves the capillaries via pericyte junctions and windows. One hour after the administration, ferritin has entered the optic gland main cells; three hours later, it is accumulated in dense-bodies. The evidence for resorption supports earlier papers reporti...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00361712
更新日期：1976-08-10 00:00:00
abstract：:In adrenalectomized rats the influence of salt loading or salt deprivation on the vasopressin and oxytocin content of the median eminence (ME) and the neural lobe (NL) was studied by means of various methods: morphometric and microphotometric analysis of aldehyde fuchsin-stained sections of ME and NL; immunohistochemi...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/BF00215904
更新日期：1986-01-01 00:00:00
abstract：:Elastic cartilage-derived cells cultured two-dimensionally with FGF2 and corticosteroid produce gel-type masses that become mature cartilage when injected into a subcutaneous pocket. This unique method has previously been clinically applied for treatments of nasal augmentation. However, the components of the gel-type ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0438-y
更新日期：2007-09-01 00:00:00
abstract：:The gross structure as well as the neuronal and non-neuronal components of the lamina ganglionaris of the locust Schistocerca gregaria are described on the basis of light- and electron-microscopical preparations of Golgi (selective silver) and ordinary histological preparations. The array of optic cartridges within th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233626
更新日期：1981-01-01 00:00:00
abstract：:The afferent lymphatic vessels of rat popliteal lymph nodes were interrupted, and the histological alterations in the lymph nodes occurring 1 to 14 weeks after operation were studied. One week after operation the number of macrophages was considerably reduced and continued to decrease during the subsequent time period...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234394
更新日期：1980-01-01 00:00:00
abstract：:Myogenesis is a complex process in which committed myogenic cells differentiate and fuse into myotubes that mature into the muscle fibres of adult organisms. This process is initiated by a cascade of myogenic regulatory factors expressed upon entry of the cells into the myogenic differentiation programme. However, ext...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-012-1364-1
更新日期：2012-06-01 00:00:00
abstract：:Two types of mitochondria-rich cells were found in the interplatelet areas of the gills of the migrating river lamprey. Both cell types are thought to be responsible for ion-transport across the gills. In the fresh-run migrant the gills are dominated by large, flask-shaped cells which show some ultrastructural similar...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221380
更新日期：1976-10-06 00:00:00
abstract：:Numerous macrophages were found aggregated in the lamina propria at the tips of villi in the small intestine of guinea pigs. These macrophages extended their pseudopodia into the epithelial lining and internalized fragments of effete enterocytes in their phagosomes. The epithelium of the villus tips was found to be in...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF02913723
更新日期：1993-03-01 00:00:00
abstract：:Caveolae or membrane vesicles are commonly observed in smooth and skeletal muscle as well as in working heart muscle. Using sections of fixed tissue and replicas of freeze-cleaved material, we show in this study that caveolae are also very numerous in sinus node cells of the rabbit, and to a lesser degree, in the atri...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234869
更新日期：1980-01-01 00:00:00
abstract：:The vacuoles occurring in rat hepatocytes after intraportal injection of retinol (33 or 67 micrograms) were examined immunohistochemically using respective antibodies against rat albumin, human retinol-binding protein, human ceruloplasmin, human alpha 1-antitrypsin, human transferrin, and human prealbumin as represent...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00261829
更新日期：1989-08-01 00:00:00
abstract：:In three species of teleosts - carp Cyprinus carpio; grass carp Ctenopharyngodon idella; and crucian carp Carassius auratus - the caudal neurosecretory system displays small, medium-sized and large neurons. Urotensin I (UI)-immunoreactive and UI-nonreactive neurons were found in all three groups; in general, the numbe...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00212550
更新日期：1986-01-01 00:00:00
abstract：:Colitis is associated with alterations in electrolyte and water transport. These changes give rise to some of the symptoms experienced by patients with colitis. Alterations in fluid flux may also contribute to increased susceptibility to mucosal injury. Recently, endogenous water channel proteins (aquaporins; AQPs), h...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0932-4
更新日期：2004-11-01 00:00:00
abstract：:Phenotype transition of vascular smooth muscle cells (VSMCs) is implicated in vascular diseases. Angiotensin-converting enzyme 2 (ACE2) is a perspective cardiovascular target due to its ability of converting angiotensin (Ang II) to Ang (1-7). Our group recently showed that ACE2 can regulate the function of endothelial...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03259-w
更新日期：2020-12-01 00:00:00
abstract：:Our previous findings have demonstrated that the rat autosomal-recessive mutation, whitish chalk-like teeth (wct), induces enamel defects resembling those of human amelogenesis imperfecta (AI) in continuously growing incisor teeth. The present study clarifies the effect of the wct mutation on the morphogenesis and cal...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0452-0
更新日期：2007-10-01 00:00:00
abstract：:Immunocytochemistry was used to determine if photoperiod and/or sex have any effect on the pattern of the luteinizing hormone-releasing hormone (LHRH) system in the brain of the Japanese quail. Immunopositive perikarya were found within three major areas of the brain: the rostral paraolfactory lobe, the preoptic, and ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222289
更新日期：1988-08-01 00:00:00
abstract：:Transplantation of a small fragment of the ileum beneath the kidney capsule in syngenic mice results in the formation of a cyst lined with proliferating intestinal epithelium. The duration of the cell cycle in the epithelium was determined (using tritiated thymidine and the FLM method) as 14.5 h, as compared with 11.5...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221125
更新日期：1977-02-02 00:00:00
abstract：:The cytotrophoblastic cell columns and trophoblastic shell of macaque placentas accumulate progressively greater amounts of intercellular material during early gestation. We studied the composition of this material in placentas collected from 22-34 days of gestation by using immunoperoxidase techniques directed to the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00328009
更新日期：1992-11-01 00:00:00
