Abstract：
:By a regular immunoperoxidase method, alpha-1-proteinase inhibitor (Api) was demonstrated in pancreatic islets in individuals with and without genetic deficiency of Api. Subsequently a double immunoperoxidase method, with two different chromogens (diaminobenzidine-brown and 4-chloro-1-naphthol-blue), was applied on the same tissue section in order to identify cells containing Api and cells secreting polypeptide hormones. Api-positive cells and hormone-secreting cells were found to be mutually exclusive indicating that Api is synthesized by previously unrecognized islet cell. The population of Api cells was significantly higher in persons with genetic deficiency than in other individuals, implying a possible compensatory hyperplasia of those cells triggered by a low level of circulating Api.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Ray MB,Zumwalt REdoi
10.1007/BF00218078subject
Has Abstractpub_date
1986-01-01 00:00:00pages
677-80issue
3eissn
0302-766Xissn
1432-0878journal_volume
243pub_type
杂志文章abstract：:Based on its proven anabolic effects on bone in osteoporosis patients, recombinant parathyroid hormone (PTH(1-34)) has been evaluated as a potential therapy for skeletal repair. In animals, the effect of PTH(1-34) has been investigated in various skeletal repair models such as fractures, allografting, spinal arthrodes...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-011-1188-4
更新日期：2012-03-01 00:00:00
abstract：:Taste buds and the peripheral nerves innervating them are two important components of the peripheral gustatory system. They require appropriate connections for the taste system to function. Neurotrophic factors play crucial roles in the innervation of peripheral sensory organs and tissues. Both brain-derived neurotrop...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0833-7
更新日期：2009-09-01 00:00:00
abstract：:Using techniques for enhanced microtubular preservation (albumin pretreatment of Gray) occipital and pyriform cortices of rats were studied by electron microscopy at various stages of development. A close structural relationship was seen between microtubules (mts), focal membrane densities, synaptic vesicles, and pres...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215777
更新日期：1983-01-01 00:00:00
abstract：:Beta-defensin 103 (DEFB103) shares little homology with 8 other members of the bovine beta-defensin family and in other species DEFB103 protein has diverse functions, including antimicrobial activity, a chemoattractant for dendritic cells, enhancing epithelial wound repair and regulating hair colour. Expression of the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2258-9
更新日期：2016-02-01 00:00:00
abstract：:Modulation of the actin cytoskeleton in chondrocytes has been used to prevent or reverse dedifferentiation and to enhance protein synthesis. We have hypothesized that an actin-modifying agent, staurosporine, could be used with fibrochondrocytes to increase the gene expression and synthesis of critical fibrocartilage p...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-008-0705-6
更新日期：2008-12-01 00:00:00
abstract：:The therapeutic potency of delivered mesenchymal stem cells (MSCs) in tissue engineering applications may be improved by priming cells toward a differentiated state via coculture with native, differentiated cells prior to implantation; however, there is a lack of understanding in what may be the most efficacious metho...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1265-8
更新日期：2012-03-01 00:00:00
abstract：:Adrenal medullary chromaffin cells are derivatives of the neural crest and are widely believed to share a common sympathoadrenal (SA) progenitor with sympathetic neurons. For decades, the adrenal cortical environment was assumed to be essential for channelling SA progenitors towards an endocrine chromaffin cell fate. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0213-5
更新日期：2006-09-01 00:00:00
abstract：:The passage of cells across the lymphatic endothelium of rat lacteals in both normal and non-pathological experimental conditions (fasting, lymphatic, stasis) was studied by means of serial thin sections and three-dimensional models. Two different pathways of transendothelial migration were observed: (1) macrophages e...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00327761
更新日期：1990-10-01 00:00:00
abstract：:Research in mammals has demonstrated a variety of regulatory effects of vasopressin and oxytocin on endocrine functions of the anterior pituitary gland. Less evidence is available regarding the hypophysiotropic action of arginine vasotocin (AVT) comprising vasopressic and oxytocic activities in birds. Some hypophysiot...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-008-0636-2
更新日期：2008-08-01 00:00:00
abstract：:In the rostral hypothalamus of the domestic fowl, the magnocellular neurosecretory nuclei show a peculiar differentiation. Golgi studies of the supraoptic and paraventricular nuclei of the fowl reveal at least two major cell types: 1) large multipolar neurons, and 2) small interneurons. Golgi impregnations provide a d...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236253
更新日期：1981-01-01 00:00:00
abstract：:This report demonstrates that the administration of testosterone (T) or 11-ketotestosterone (11-KT) to sexually immature (8 wks old) male platyfish (Xiphophorus maculatus) of early- and late-maturing genotypes affects the synthesis and/or release of luteinizing hormone-releasing hormone (LHRH), as assessed by immunocy...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218552
更新日期：1986-01-01 00:00:00
abstract：:The capsule of the muscle spindle from the anterior and posterior latissimus dorsi muscles of the adult domestic chicken has been studied with the electron microscope. As in other species, two distinct portions of the spindle capsule are distinguished: an outer capsule and an inner capsule. The outer capsule is struct...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220126
更新日期：1976-02-25 00:00:00
abstract：:Our aim is to gain insight into the mechanisms underlying the anti-atrophic effects of leucine, namely, the way that this amino acid can restrain the up-regulation of MuRF1 and Mafbx/Atrogin-1 in muscle atrophy. Male rats received dietary leucine supplementation for 1-3 days, during which time their hind limbs were im...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-017-2614-z
更新日期：2017-08-01 00:00:00
abstract：:The distribution of serotonin-immunoreactive cells in the lung of 4 species of reptiles was investigated. Serotonin-containing cells were found forming groups in the interconnecting septa in all 4 species studied, and also as solitary cells in Testudo graeca and Mauremys caspica. Serotonin-containing cells were also l...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216504
更新日期：1987-06-01 00:00:00
abstract：:Mole rat bone marrow cells and peritoneal eosinophils are used to study granule morphological maturation by quantitative microscopy. The bulk eosinophil granule content is pre-stored in unique granular structures known as crystalloid or secondary granules. Mole rat eosinophil granules exhibit the basic structure of an...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2189-5
更新日期：2015-10-01 00:00:00
abstract：:The fine structure of one of the cellular components of the nucleus recesses lateralis of trout is described. These cells have an enormously developed smooth endoplasmic reticulum which makes their identification easy. The relationship of this cell type with the ventricular cavity, neighbouring cells and the presence ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00206343
更新日期：1982-01-01 00:00:00
abstract：:Two types of mitochondria-rich cells were found in the interplatelet areas of the gills of the migrating river lamprey. Both cell types are thought to be responsible for ion-transport across the gills. In the fresh-run migrant the gills are dominated by large, flask-shaped cells which show some ultrastructural similar...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221380
更新日期：1976-10-06 00:00:00
abstract：:With regard to the protein content, as analysed cytophotometrically, of hepatocytes from rats kept under a 12L 12D photoperiod (photophase 7:00-19:00), the following facts have been established: 1) Hepatocytes of different classes of ploidy all demonstrate, more or less equally, daily variations in protein content and...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221865
更新日期：1986-01-01 00:00:00
abstract：:Enzyme-histochemical methods were used to study the metabolic activity of specialized ependyma of the ventrolateral walls and floor of the third ventricle in young male and female rats during the "critical period" of sexual differentiation of the hypothalamus (one week after birth). Histochemical tests were conducted ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220328
更新日期：1976-10-13 00:00:00
abstract：:Freeze-etch preparations of mesothelial cells taken from the peritoneum of mouse reveal the presence of vesicles invaginating the apical and the basal cell surfaces. These vesicles are scarcely seen within the cytoplasm. Long tortuous tubular profiles extend for considerable distance within the cytoplasm and are frequ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219271
更新日期：1976-10-01 00:00:00
abstract：:The ability of levamisole (LVS) to correct the effect of thymectomy on splenic T-cell population in Bufo bufo larvae was tested. Using the nonspecific acid alpha-naphthyl acetate esterase (ANAE) technique, the T-lymphocytes displayed a characteristic reddish brown spot (T-pattern). The total number of white cells per ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00204789
更新日期：1982-01-01 00:00:00
abstract：:Two dozen hybrid clones were produced by fusion of diploid embryonic stem (ES) cells positive for green fluorescent protein (GFP) with tetraploid fibroblasts derived from DD/c and C57BL-I(I)1RK mice. Cytogenetic analysis demonstrated that most cells from these hybrid clones contained near-hexaploid chromosome sets. Ad...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-0987-3
更新日期：2010-06-01 00:00:00
abstract：:Germ cells of human fetuses aged 7-13 weeks were studied. Dense fibrous material called nuage was found in the cytoplasm of human fetal germ cells. The nuage increased in frequency in the germ cells during the interval studied. In oogonia the nuage occurred much more frequently than in spermatogonia and the frequency ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00209243
更新日期：1978-11-09 00:00:00
abstract：:Although the function and effects of many growth factors and extracellular matrix (ECM) molecules have been described for several periodontal tissues in vivo and in vitro, the molecular interactions involved in the communication between cells of the periodontal ligament and the alveolar bone are poorly understood. To ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-1026-z
更新日期：2005-03-01 00:00:00
abstract：:Within seminiferous tubules, Sertoli cells form three types of actin-filament-containing cell junctions, viz., tight junctions, ectoplasmic specializations, and tubulobulbar complexes. These Sertoli cell junctions are involved in the formation of the blood-testis barrier, germ cell translocation, and the release of sp...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0864-z
更新日期：2004-05-01 00:00:00
abstract：:A total of 20 Golgi-impregnated cone horizontal cells of Nannacara anomala (Cichlidae) were studied in alternating semi- and ultrathin sections in order to examine their connections with the overlying square mosaic of equal double and central single cones. Cone horizontal cells exhibiting three types of processes: (a)...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220825
更新日期：1976-11-24 00:00:00
abstract：:Epidermal septate junctions of Nereis sp. and Cirriformia sp. fixed with OsO4 or glutaraldehyde/OsO4 display variable structure in electron micrographs. In transverse section the septa are often indistinct and obscured by opaque material that fills the junctional cleft. Septa (spaced at 180--280 A) are more clearly de...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222150
更新日期：1976-10-22 00:00:00
abstract：:Two different fixative procedures (immersion and perfusion) and four different fixative solutions were used in order to obtain the best preservation of the brush cells of the common bile duct of the rat. The results indicate that only perfusion fixation through the common bile duct is suitable, independent of the fixa...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210353
更新日期：1981-01-01 00:00:00
abstract：:During the reproductive period of the male stickleback, structural and functional changes of the kidney take place, both in the glomeruli and in the renal tubule cells. The structural changes in the glomeruli involve almost all glomerular components and point to a reduction of the glomerular filtration rate. The purpo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210146
更新日期：1981-01-01 00:00:00
abstract：:Thin sections after bile duct ligation showed that the depth of tight junctions appeared to increase and that the distance between individual punctate contacts appeared to become irregular and wider than in controls. The freeze fracture replicas clearly demonstrated these changes in the tight junction morphology. Chan...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236724
更新日期：1978-12-28 00:00:00
