Synaptic development and microtubule organization.

Abstract:

:Using techniques for enhanced microtubular preservation (albumin pretreatment of Gray) occipital and pyriform cortices of rats were studied by electron microscopy at various stages of development. A close structural relationship was seen between microtubules (mts), focal membrane densities, synaptic vesicles, and presynaptic dense projections (pre-dps) during maturation. Mts were seen in the neonates to be focused onto the inner surface of immature axonic profiles merging or sometimes fragmenting there. Focal densities occur at these attachment sites and thereafter synaptic vesicles clothe the mts and abut onto these presumed primordial pre-dps. Thus, mts may contribute to the initial formation of pre-dps as well as their maintenance in the adult and may act to channel the first synaptic vesicles to the site of eventual synaptic contact and transmitter release.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Westrum LE,Gray EG,Burgoyne RD,Barron J

doi

10.1007/BF00215777

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

93-102

issue

1

eissn

0302-766X

issn

1432-0878

journal_volume

231

pub_type

杂志文章
  • Immunohistochemical study on the development of CRF-containing neurons in the hypothalamus of the rat.

    abstract::Appearance of immunoreactive corticotropin-releasing factor (CRF)-containing neurons was studied in developing hypothalamus of the rat by use of antisera against rat- and ovine CRF. These neurons were first recognized in the lateral and paraventricular nuclei on days 15.5 and 16.5 of gestation, respectively, when anti...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219870

    authors: Daikoku S,Okamura Y,Kawano H,Tsuruo Y,Maegawa M,Shibasaki T

    更新日期:1984-01-01 00:00:00

  • Significance of the peri-insular extracellular matrix for islet isolation from the pancreas of rat, dog, pig, and man.

    abstract::The presence and distribution in the peri-insular region of extracellular matrix, and in particular basement membrane, was investigated in a comparative study comprising pancreata of rat, dog, pig, and man. Basement membrane markers, collagen type-IV and laminin, were determined immunohistochemically. Additional infor...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00318700

    authors: van Deijnen JH,Hulstaert CE,Wolters GH,van Schilfgaarde R

    更新日期:1992-01-01 00:00:00

  • Gene expression profiles of estrogen receptors α and β in the fetal bovine hypothalamus and immunohistochemical characterization during development.

    abstract::Steroid hormones intervene in the structural and functional regulation of neuronal processes during development and thus determine brain differentiation. The effects of estrogens are mediated by two transcription factors, namely estrogen receptor α (ER-α) and estrogen receptor β (ER-β), that regulate the expression of...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-014-2023-5

    authors: Panin M,Corain L,Montelli S,Cozzi B,Peruffo A

    更新日期:2015-02-01 00:00:00

  • The fine structure of the carapace integument of Daphnia magna Straus (Crustacea Branchiopoda).

    abstract::The structure of the two integumental layers comprising the carapace of female D. magna was examined at several points through the molt cycle. The epicuticle and procuticle are simple in organisation; pore canalsare absent but intracuticular fibres are present, forming complexes with invaginations of the epidermal pla...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00214213

    authors: Halcrow K

    更新日期:1976-06-14 00:00:00

  • Attenuated regenerative properties in human periodontal ligament-derived stem cells of older donor ages with shorter telomere length and lower SSEA4 expression.

    abstract::Periodontal ligament (PDL) stem cell properties are critical in the periodontal tissue regeneration for periodontitis. Previously, we have demonstrated that cigarette smoking attenuates PDL-derived stem cell (PDLSC) regenerative properties. Here, we report the findings on the regenerative properties of human PDLSCs wi...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-020-03176-y

    authors: Ng TK,Chen CB,Xu C,Xu Y,Yao X,Huang L,Liang JJ,Cheung HS,Pang CP,Huang Y

    更新日期:2020-07-01 00:00:00

  • A novel homozygous nonsense mutation in CAST associated with PLACK syndrome.

    abstract::Peeling skin syndrome is a heterogeneous group of rare disorders. Peeling skin, leukonychia, acral punctate keratoses, cheilitis and knuckle pads (PLACK syndrome, OMIM616295) is a newly described form of PSS with an autosomal recessive mode of inheritance. We report a 5.5-year-old boy with features of PLACK syndrome. ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-019-03077-9

    authors: Temel ŞG,Karakaş B,Şeker Ü,Turkgenç B,Zorlu Ö,Sarıcaoğlu H,Oğur Ç,Kütük Ö,Kelsell DP,Yakıcıer MC

    更新日期:2019-11-01 00:00:00

  • Analysis and in situ detection of cholecalcin messenger RNA (9000 Mr CaBP) in the uterus of the pregnant rat.

    abstract::The molecular cloning of a cDNA fragment synthesised from rat duodenal mRNA coding for cholecalcin (calbindin), a 9000 Mr vitamin D-induced calcium-binding protein (CaBP), has been previously described. DNA/RNA hybridisation assays have been used to examine CaBP mRNA production in the uterine horns and duodena of preg...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00216546

    authors: Warembourg M,Perret C,Thomasset M

    更新日期:1987-01-01 00:00:00

  • Fine structure of the sensilla of Peripatopsis moseleyi (Onychophora).

    abstract::Three types of sensilla occurring on the lips and on the antennae of Peripatopsis moseleyi have been investigated by scanning and transmission electron microscopy. On the lips sensory spines can be found which contain numerous cilia originating from bipolar receptor cells. They reach the tip of the spine where the cut...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00220613

    authors: Storch V,Ruhberg H

    更新日期:1977-02-14 00:00:00

  • Genetic susceptibility to neuroblastoma: current knowledge and future directions.

    abstract::Neuroblastoma, a malignancy of the developing peripheral nervous system that affects infants and young children, is a complex genetic disease. Over the past two decades, significant progress has been made toward understanding the genetic determinants that predispose to this often lethal childhood cancer. Approximately...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-018-2820-3

    authors: Ritenour LE,Randall MP,Bosse KR,Diskin SJ

    更新日期:2018-05-01 00:00:00

  • Ultrastructure and distribution of somatostatin-like immunoreactive neurons and nerve fibres in the coeliac ganglion of cats.

    abstract::Somatostatin-like immunoreactivity was localized in nerve cell bodies and nerve terminals in the cat coeliac ganglion. Two types of somatostatin-immunoreactive cell bodies were revealed, the first being large (diameter 35 microns), numerous and weakly labelled, whereas the second was considerably smaller (diameter 10....

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00327290

    authors: Fehér E,Burnstock G

    更新日期:1991-03-01 00:00:00

  • Role of Angiopoietins and Tie receptor tyrosine kinases in angiogenesis and lymphangiogenesis.

    abstract::This review focuses on the signaling system involving the Angiopoietin1/Tie2 receptor, which appears to be involved in the secondary stages of blood vessel formation. Although this system is crucial for blood and lymphatic vessel formation, identifying its precise role in embryonic and adult vascular biology has been ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-003-0749-6

    authors: Thurston G

    更新日期:2003-10-01 00:00:00

  • Protein kinase Cα inhibitor enhances the sensitivity of human pancreatic cancer HPAC cells to Clostridium perfringens enterotoxin via claudin-4.

    abstract::Protein kinase C (PKC) is overexpressed in cancer, including pancreatic cancer, compared with normal tissue. Moreover, PKCα is considered one of the biomarkers for the diagnosis of cancers. In several human cancers, the claudin tight junction molecules are abnormally regulated and are thus promising molecular targets ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-011-1287-2

    authors: Kyuno D,Kojima T,Ito T,Yamaguchi H,Tsujiwaki M,Takasawa A,Murata M,Tanaka S,Hirata K,Sawada N

    更新日期:2011-12-01 00:00:00

  • Expression of stem cell factors in the adult sea cucumber digestive tube.

    abstract::Homeostatic cell turnover has been extensively characterized in mammals. In their adult tissues, lost or aging differentiated cells are replenished by a self-renewing cohort of stem cells. The stem cells have been particularly well studied in the intestine and are clearly identified by the expression of marker genes i...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-017-2692-y

    authors: Mashanov V,Zueva O,Mashanova D,García-Arrarás JE

    更新日期:2017-12-01 00:00:00

  • Projection pathways, co-existence of peptides and synaptic organization of nerve fibers in the inferior mesenteric ganglion of the guinea-pig.

    abstract::The presence of immunoreactive enkephalin, dynorphin, vasoactive intestinal polypeptide, cholecystokinin, substance P and neuropeptide Y in nerve fibers that project to the guinea-pig inferior mesenteric ganglion was analysed, after different denervation and ligation procedures. A quantitative analysis demonstrates th...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219741

    authors: Masuko S,Chiba T

    更新日期:1988-09-01 00:00:00

  • Cellular and subcellular distribution of the calcium-binding protein NCS-1 in the central nervous system of the rat.

    abstract::NCS-1 (neuronal calcium sensor) is a recently characterized member of a highly conserved neuron-specific family of calcium-binding proteins, which also includes frequenin and recoverin. The cellular and subcellular distributions of NCS-1 in the rat nervous system were investigated using light- and electron-microscopic...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051246

    authors: Martone ME,Edelmann VM,Ellisman MH,Nef P

    更新日期:1999-03-01 00:00:00

  • Ultrastructural distribution of endogenous immunoglobulin-G in human term amniochorion.

    abstract::Maternal immunoglobulin-G (IgG) is known to be transported across the placental syncytiotrophoblast during the period when the human fetus is incapable of manufacturing these defensive molecules. In this study we investigated the possible role of the amniochorion, that surrounds the amniotic cavity in which the fetus ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00583405

    authors: Bright NA,Ockleford CD

    更新日期:1995-08-01 00:00:00

  • Calretinin and calbindin in the retina of the developing chick.

    abstract::Calretinin and calbindin-D28k are two calcium-binding proteins that are present in largely different sets of nerve cells in the central nervous system. Their appearance during development of the chick retina was studied by immunohistochemistry and Western blots. The patterns are mature one day before hatching. Each ce...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00313956

    authors: Ellis JH,Richards DE,Rogers JH

    更新日期:1991-05-01 00:00:00

  • The connectivity of cones and cone horizontal cells in a mosaic-type teleost retina.

    abstract::A total of 20 Golgi-impregnated cone horizontal cells of Nannacara anomala (Cichlidae) were studied in alternating semi- and ultrathin sections in order to examine their connections with the overlying square mosaic of equal double and central single cones. Cone horizontal cells exhibiting three types of processes: (a)...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00220825

    authors: Wagner HJ

    更新日期:1976-11-24 00:00:00

  • Occurrence of nuage in fetal human germ cells.

    abstract::Germ cells of human fetuses aged 7-13 weeks were studied. Dense fibrous material called nuage was found in the cytoplasm of human fetal germ cells. The nuage increased in frequency in the germ cells during the interval studied. In oogonia the nuage occurred much more frequently than in spermatogonia and the frequency ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00209243

    authors: Kellokumpu-Lehtinen PL,Söderström KO

    更新日期:1978-11-09 00:00:00

  • Ultrastructure and composition of Call-Exner bodies in bovine follicles.

    abstract::Call-Exner bodies are present in ovarian follicles of a range of species including human and rabbit, and in a range of human ovarian tumors. We have also found structures resembling Call-Exner bodies in bovine preantral and small antral follicles. Hematoxylin and eosin staining of single sections of bovine ovaries has...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051298

    authors: van Wezel IL,Irving-Rodgers HF,Sado Y,Ninomiya Y,Rodgers RJ

    更新日期:1999-05-01 00:00:00

  • Combined effect of ligament stem cells and umbilical-cord-blood-derived CD34+ cells on ligament healing.

    abstract::Transplantation of ligament-tissue-derived stem cells has become a promising approach in the repair of injured ligament. Neovascularization plays an important role in ligament healing and remodeling. Recently, human umbilical-cord-blood-derived CD34+ cells have been reported to contribute to neoangiogenesis. Therefore...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-015-2250-4

    authors: Jiang D,Yang S,Gao P,Zhang Y,Guo T,Lin H,Geng H

    更新日期:2015-12-01 00:00:00

  • Monoclonal antibodies SMI 311 and SMI 312 as tools to investigate the maturation of nerve cells and axonal patterns in human fetal brain.

    abstract::Neurofilaments, which are exclusively found in nerve cells, are one of the earliest recognizable features of the maturing nervous system. The differential distribution of neurofilament proteins in varying degrees of phosphorylation within a neuron provides the possibility of selectively demonstrating either somata and...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051013

    authors: Ulfig N,Nickel J,Bohl J

    更新日期:1998-03-01 00:00:00

  • Immunoreactivity for calcitonin gene-related peptide in neuroepithelial bodies of the newborn cat.

    abstract::Immunoreactivity for calcitonin gene-related peptide is demonstrated for the first time in neuroepithelial bodies in the lung of newborn cats after Bouin fixation and embedding in paraffin. The intense staining clearly identifies these bodies at the level of bronchioli and alveoli. Occasionally, single neuroepithelial...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00215517

    authors: Scheuermann DW,Timmermans JP,Adriaensen D,De Groodt-Lasseel MH

    更新日期:1987-08-01 00:00:00

  • Migration of cranial neural crest cells to the pharyngeal arches and heart in rat embryos.

    abstract::The existence of a neural crest cell migration pathway from occipital levels of the hindbrain into the heart was suspected in mammalian embryos because it had previously been identified in avian embryos and because the Di George anomaly, an association between craniofacial and cardiac malformations, is most easily exp...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00338048

    authors: Fukiishi Y,Morriss-Kay GM

    更新日期:1992-04-01 00:00:00

  • The amazing complexity of insect midgut cells: types, peculiarities, and functions.

    abstract::The insect midgut epithelium represents an interface between the internal and the external environment and it is the almost unique epithelial tissue by which these arthropods acquire nutrients. This epithelium is indeed able to produce digestive enzymes and to support vectorial transport of small organic nutrients, io...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-019-03076-w

    authors: Caccia S,Casartelli M,Tettamanti G

    更新日期:2019-09-01 00:00:00

  • Ultrastructural characterization of interstitial cells of Cajal in the rat small intestine using control and Ws/Ws mutant rats.

    abstract::Interstitial cells in the myenteric plexus and the deep muscular plexus of the small intestine of the c-kit mutant rats (Ws/Ws) and their normal siblings (+/+) were studied. c-Kit immunoreactivity was detected in two regions corresponding to the myenteric plexus and the deep muscular plexus in the jejunum of +/+ rats,...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051119

    authors: Horiguchi K,Komuro T

    更新日期:1998-08-01 00:00:00

  • Regeneration of static-load-degenerated articular cartilage extracellular matrix by vitamin C supplementation.

    abstract::The effect of a physiological dose of vitamin C (100 microg/ml) on goat articular cartilage chondrocytes cultured in an alginate matrix and subjected to static pressurization of 2.4 MPa was investigated. Biochemical analyses of DNA, glycosaminoglycan (GAG), collagen and protease activity were carried out in various ma...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-008-0666-9

    authors: Sharma G,Saxena RK,Mishra P

    更新日期:2008-10-01 00:00:00

  • Localization of neuropeptide Y and atrial natriuretic peptide in the endothelial cells of human umbilical blood vessels.

    abstract::The localization of neuropeptide Y (NPY) and atrial natriuretic peptide (ANP) in the endothelial cells of human umbilical blood vessels was studied using the pre-embedding peroxidase-antiperoxidase (PAP) technique for electron microscopy and avidin-biotin-complex (ABC) immunostaining for endothelial cells cultured fro...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00323584

    authors: Cai WQ,Bodin P,Sexton A,Loesch A,Burnstock G

    更新日期:1993-04-01 00:00:00

  • Early stages of endothelial wound repair: conversion of quiescent to migrating endothelial cells involves tyrosine phosphorylation and actin microfilament reorganization.

    abstract::Endothelial repair to reestablish structural integrity following wounding is a complex process. Since the actin cytoskeleton undergoes specific changes in distribution as quiescent endothelial cells switch to activated migrating cells over a 6-h period following wounding (Lee et al. 1996), we studied tyrosine phosphor...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051370

    authors: Lee TY,Gotlieb AI

    更新日期:1999-09-01 00:00:00

  • Effects of an antiandrogen, cyproterone acetate, on the kidney of the three-spined stickleback (Gasterosteus aculeatus L.).

    abstract::The fine structure of the kidney is studied in the sexually mature male three-spined stickleback after administration of an antiandrogen, cyproterone acetate. Under these conditions, the dedifferentiation of renal tubules is characterized by the same involutive processes as those induced by castration, with the differ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00220324

    authors: Mourier JP

    更新日期:1976-10-13 00:00:00