Abstract：
:The existence of a neural crest cell migration pathway from occipital levels of the hindbrain into the heart was suspected in mammalian embryos because it had previously been identified in avian embryos and because the Di George anomaly, an association between craniofacial and cardiac malformations, is most easily explained on the basis of abnormal neural crest cell migration to all of the affected structures. In order to demonstrate the existence of this pathway, neural crest cells were labelled in situ in rat embryos with the fluorescent dye DiI, and the embryos cultured for up to 48 h. Cells labelled between occipital somites 1 and 2 or 3 and 4 migrated within and dorsal to the third and fourth pharyngeal arches and into the outflow tract of the heart (conus cordis and truncus arteriosus). The cardiac labelling was in individually visible cells, in contrast to the mass of fluorescence seen in the pharyngeal and dorsal mesenchyme. Within the outflow tract wall, the labelled cells were enmeshed by strands of alcian blue-stained extracellular matrix. There was no labelling of cardiac cells following injections just rostral to, or just caudal to, somites one and four. This study establishes the existence and precise levels of origin of the 'cardiac' neural crest in a mammalian embryo.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Fukiishi Y,Morriss-Kay GMdoi
10.1007/BF00338048keywords:
subject
Has Abstractpub_date
1992-04-01 00:00:00pages
1-8issue
1eissn
0302-766Xissn
1432-0878journal_volume
268pub_type
杂志文章abstract：:The interstitial cells of Cajal (ICCs) are important mediators of gastrointestinal (GI) motility because of their role as pacemakers in the GI tract. In addition to their function, ICCs are also structurally distinct cells most easily identified by their ultra-structural features and expression of the tyrosine kinase ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-012-1434-4
更新日期：2012-08-01 00:00:00
abstract：:We have analyzed the distribution of neural crest-derived precursors and the expression of catecholaminergic and neuronal markers in developing adrenal tissue of chick embryos. Undifferentiated neural crest cells are found in presumptive adrenal regions from embryonic day 3 (E3) onward. An increasing proportion of cel...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0996-1
更新日期：2005-01-01 00:00:00
abstract：:Among heterogeneous S100β-protein-positive (S100β-positive) cells, star-like cells with extended cytoplasmic processes, the so-called folliculo-stellate cells, envelop hormone-producing cells or interconnect homophilically in the anterior pituitary. S100β-positive cells are known, from immunohistochemistry, to emerge ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2256-y
更新日期：2016-02-01 00:00:00
abstract：:Previous neurohistological studies have been extended to include the structures contained solely or mainly within the junctional esophageal segment which may play an important role in the sphincter mechanism. The main findings were: 1) a progressive cranio-caudal thickening of the muscularis mucosae; 2) a conspicuous ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215998
更新日期：1976-05-26 00:00:00
abstract：:The electric organs of embryonic Torpedo marmorata have been reacted with three cationic stains to evaluate the appearance and distribution of anionic sites. Ruthenium red, alcian blue and lysozyme were used at different pHs and found to react in a time-related manner to anionic components within the interelectrocyte ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214662
更新日期：1987-10-01 00:00:00
abstract：:Call-Exner bodies are present in ovarian follicles of a range of species including human and rabbit, and in a range of human ovarian tumors. We have also found structures resembling Call-Exner bodies in bovine preantral and small antral follicles. Hematoxylin and eosin staining of single sections of bovine ovaries has...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051298
更新日期：1999-05-01 00:00:00
abstract：:Cholinergic neurons have been revealed in the enteric nervous system by functional and biochemical studies but not by antibodies that provide excellent localisation of the synthesising enzyme, choline acetyltransferase (ChAT), in the central nervous system. In order to determine whether a newly described peripheral fo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0652-6
更新日期：2003-01-01 00:00:00
abstract：:Unfertilized eggs commonly lack centrioles, which are usually provided by the male gamete at fertilization, and are unable to assemble functional reproducing centrosomes. However, some insect species lay eggs that develop to adulthood without a contribution from sperm. We report that the oocyte of the parthenogenetic ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0253-x
更新日期：2006-12-01 00:00:00
abstract：:Adult male Branta canadensis maxima were collected from a nonmigratory feral population during their premolt, molt and postmolt phases. Lean dry weight of the pectoralis muscle decreased significantly (p less than or equal to 0.0001) during molt, as a result of disuse atrophy. Histochemical analysis revealed that the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215763
更新日期：1987-03-01 00:00:00
abstract：:Renovascular hypertension (RVH) is a progressive disease, leading to chronic kidney disease when untreated and no specific treatment is available. Therefore, development of new therapeutic modalities is imperative. RVH is triggered by renal artery stenosis and subsequent renin-angiotensin-aldosterone system activation...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-017-2602-3
更新日期：2017-08-01 00:00:00
abstract：:The hormone-induced pigment dispersion in primary cultures of xanthophores of goldfish (Carassius auratus L.) has been shown to involve the dispersion of not only carotenoid droplets but also of smooth endoplasmic reticulum. The dispersion of these organelles is inhibited by cytochalasin B and is accompanied by thinni...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219555
更新日期：1978-07-10 00:00:00
abstract：:The choroid plexus from the lateral ventricles of 18-day chick embryos was cultivated as an organ in medium 199 until the degeneration of the stroma. Selected plexuses forming an empty epithelial sac were then incubated with enzyme-treated human immunoglobulin (5S-antibody) and with native human immunoglobulin (7S-ant...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00237886
更新日期：1980-01-01 00:00:00
abstract：:By using an antiserum raised against a crustacean beta-pigment-dispersing hormone (PDH), the distribution and chemical neuroanatomy of PDH-like immunoreactive neurons was investigated in the central nervous system of the gastropod snails, Helix pomatia and Lymnaea stagnalis. The number of immunoreactive cells in the H...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051240
更新日期：1999-02-01 00:00:00
abstract：:The cytotrophoblastic cell columns and trophoblastic shell of macaque placentas accumulate progressively greater amounts of intercellular material during early gestation. We studied the composition of this material in placentas collected from 22-34 days of gestation by using immunoperoxidase techniques directed to the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00328009
更新日期：1992-11-01 00:00:00
abstract：:The relationship between nitric oxide synthase (NOS)- and galanin-immunoreactive nerve terminals and the origin of NOS-immunoreactive nerve terminals on the motor endplates in the striated muscles of the rat esophagus was investigated. Double immunohistochemical staining revealed a dual innervation of motor endplates ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051230
更新日期：1999-02-01 00:00:00
abstract：:This report describes a phenotyping study of differentiating human skeletal muscle cells in tissue culture. Satellite cells (adult myoblasts), isolated from biopsy material, showed a proliferative behaviour in high-nutrition medium, but fused to form myotubes when grown in low-nutrition medium. The expression and stru...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00381893
更新日期：1992-10-01 00:00:00
abstract：:We compare the ultrastructure of the gerbil sublingual gland as seen after cryofixation followed by substitution with osmium tetroxide, with the more familiar appearance of material processed by glutaraldehyde-osmium chemical fixation. After primary cryofixation of fresh salivary glands, the nuclei of the mucous cells...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219075
更新日期：1987-11-01 00:00:00
abstract：:Communication between individuals is critical for species survival, reproduction, and expansion. Most terrestrial species, with the exception of humans who predominantly use vision and phonation to create their social network, rely on the detection and decoding of olfactory signals, which are widely known as pheromone...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-020-03376-6
更新日期：2021-01-12 00:00:00
abstract：:Horseradish peroxidase (HRP) was injected into the left dorsal column nuclei of adult cats. Large dorsal funiculi axons of the C3, C5, C8 and L7 segments were searched for HRP-activity after 12, 24, 36 and 48h using light and electron microscopy. Accumulations of intra-axonal HRP-positive bodies occurred at nodes of R...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050513
更新日期：1996-01-01 00:00:00
abstract：:The brood pouch of the male pipefish (Syngnathus schlegeli) is a ventral organ located on the tail, with the anterior region closely associated with the genital pore. The embryos in the pouch are attached to highly vascularized placenta-like tissue which seals the pouch folds from inside during incubation. The epithel...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051220
更新日期：1999-01-01 00:00:00
abstract：:The opioid peptide dynorphin A (1-17) is the third transmitter identified in the striatonigral projection, the other two being gamma-aminobutyric acid (GABA) and substance P. The ultrastructural features of the dynorphinergic terminals in substantia nigra/pars reticulata were studied using pre-embedding immunocytochem...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00329443
更新日期：1990-07-01 00:00:00
abstract：:Transgenic rats for the murine Ren-2 gene display high blood pressure, low circulating levels of angiotensin II, and high renin content in the adrenal glands. Moreover, transgenic rats possess an increased aldosterone secretion (maximal from 6 to 18 weeks of age), paralleling the development of hypertension. To invest...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305774
更新日期：1994-10-01 00:00:00
abstract：:Serotonin immunoreactivity was localized in hearts of the opisthobranch gastropod, Aplysia californica (sea hare) and several species of bivalve mollusks, the heterodonts, Mercenaria mercenaria (quahog or cherry stone clam), Protothaca staminea (little neck clam), and the pteriomorphs, Hinnites multirugosus (rock scal...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00353897
更新日期：1992-09-01 00:00:00
abstract：:Expression of heat-shock protein 47 in intact and fibrotic liver and in hepatic constituent cells was investigated in mice. Immunohistochemical study of intact liver and Western blot analysis of the protein from isolated liver cells revealed that stellate cells and smooth muscle cells of interlobular vessels, but not ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050594
更新日期：1996-05-01 00:00:00
abstract：:The expression patterns of three microtubule-associated proteins (MAP1A, MAP1B, and MAP2A&B) were investigated in the developing optic tectum. Expression of MAP1B and middle-molecular-weight peptide of neurofilament (NF-M) was first observed in the same mesencephalic cells on day 3 of incubation, indicating that neuro...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0796-z
更新日期：2003-12-01 00:00:00
abstract：:Endothelial cells separate the intra- and extravascular space and regulate transport processes between these compartments. Since intercellular junctions are required for these specific cell functions, the cell-cell contacts in the permanent cell line ECV304 were systematically analyzed and compared with human umbilica...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051340
更新日期：1999-07-01 00:00:00
abstract：:The enteric nervous system appears to play a pivotal role in the functional recovery of the gastrointestinal tract after partial resection and reanastomosis, but the structural changes following surgery are not fully understood. The present study was designed to clarify the processes of myenteric plexus regeneration u...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00327773
更新日期：1994-08-01 00:00:00
abstract：:Immunoreactivity for calcitonin gene-related peptide is demonstrated for the first time in neuroepithelial bodies in the lung of newborn cats after Bouin fixation and embedding in paraffin. The intense staining clearly identifies these bodies at the level of bronchioli and alveoli. Occasionally, single neuroepithelial...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215517
更新日期：1987-08-01 00:00:00
abstract：:Mouse milk fat globule-EGF factor 8, MFG-E8, is the ortholog to the human mammary tumor marker, lactadherin, and comprises two spliced variants, the L and S forms. Recent studies have suggested that MFG-E8-L produced by macrophages and Langerhans cells in the skin serves as a linker between phagocytic cells and apopto...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1148-y
更新日期：2005-08-01 00:00:00
abstract：:Although the cerebrospinal fluid-contacting neurons of the avian paraventricular organ exhibit considerable amounts of catecholamines, they show no tyrosine hydroxylase immunoreactivity. In the quail embryo, the development of these neurons has been studied using the paraformaldeyde-glutaraldeyde method for the fluore...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00307970
更新日期：1995-07-01 00:00:00
