Abstract：
:Appearance of immunoreactive corticotropin-releasing factor (CRF)-containing neurons was studied in developing hypothalamus of the rat by use of antisera against rat- and ovine CRF. These neurons were first recognized in the lateral and paraventricular nuclei on days 15.5 and 16.5 of gestation, respectively, when antiserum against rat CRF was employed. Antiserum against ovine CRF revealed the cells two days later exclusively in the latter nucleus. In both nuclei, the neurons increased in number with development. The neurons in the paraventricular nucleus appeared to project their immunoreactive processes to the median eminence via the periventricular and lateral pathways. In the median eminence, the immunoreaction with antiserum to rat CRF was first recognized in its anterior portion in the form of dots on day 16.5 of gestation but as beaded fibers in the external layer on day 17.5; these structures increased in amount with development in rostro-caudal direction. Although antiserum to ovine CRF was less potent in immunostainability than antiserum to rat CRF, it also revealed the beaded fibers in the median eminence on day 17.5 of gestation. Since evidence is available that the paraventricular nucleus is involved in corticotropin release, it is concluded that, in rats, the hypothalamic regulatory mechanism controlling the release of corticotropin initially appears on days 16.5-17.5 of gestation.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Daikoku S,Okamura Y,Kawano H,Tsuruo Y,Maegawa M,Shibasaki Tdoi
10.1007/BF00219870subject
Has Abstractpub_date
1984-01-01 00:00:00pages
539-44issue
3eissn
0302-766Xissn
1432-0878journal_volume
238pub_type
杂志文章abstract：:Myelin formation in cultures of previously dissociated spinal cord from foetal mice is described. In addition to the expected pattern of myelination, in which axons are closely wrapped by myelin lamellae, redundant folds of myelin have been found, as have double sheaths surrounding a single axon. Hypotheses concerning...
journal_title：Cell and tissue research
pub_type： 杂志文章
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
pub_type： 杂志文章
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更新日期：1978-05-18 00:00:00
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journal_title：Cell and tissue research
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更新日期：1979-02-15 00:00:00
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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更新日期：1990-09-01 00:00:00
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更新日期：2013-12-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
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更新日期：1977-04-07 00:00:00
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journal_title：Cell and tissue research
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更新日期：1994-08-01 00:00:00
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journal_title：Cell and tissue research
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更新日期：1978-08-25 00:00:00
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pub_type： 杂志文章
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更新日期：2002-08-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-02-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s00441-004-1067-3
更新日期：2005-04-01 00:00:00
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pub_type： 杂志文章
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更新日期：2003-11-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305382
更新日期：1994-01-01 00:00:00
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journal_title：Cell and tissue research
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更新日期：2013-12-01 00:00:00
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更新日期：2008-04-01 00:00:00
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journal_title：Cell and tissue research
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pub_type： 杂志文章
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更新日期：1990-04-01 00:00:00
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更新日期：2012-12-01 00:00:00
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更新日期：2016-10-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00399522
更新日期：1976-09-20 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1092-x
更新日期：2005-06-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1142-4
更新日期：2005-09-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210102
更新日期：1981-01-01 00:00:00
abstract：:In amniotes, the developmental potentials of neural crest cells differ between the cranium and the trunk. These differences may be attributable to the different expression patterns of Hox genes between cranial and trunk neural crest cells. However, little is known about the factors that control Hox genes expression in...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0827-5
更新日期：2009-09-01 00:00:00
abstract：:Neuroblastoma is an embryonal malignancy that affects normal development of the adrenal medulla and paravertebral sympathetic ganglia in early childhood. Extensive studies have revealed the molecular characteristics of human neuroblastomas, including abnormalities at genome, epigenome and transcriptome levels. However...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
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更新日期：2018-05-01 00:00:00
