Abstract:
:In amniotes, the developmental potentials of neural crest cells differ between the cranium and the trunk. These differences may be attributable to the different expression patterns of Hox genes between cranial and trunk neural crest cells. However, little is known about the factors that control Hox genes expression in neural crest cells. The present data demonstrate that retinoic acid (RA) treatment and the activation of Wnt signaling induce Hoxa2 and Hoxd9 expression, respectively, in mouse mesencephalic neural crest cells, which never express Hox genes in vivo. Furthermore, Wnt signaling suppresses the induction of Hoxa2. We also demonstrate that these factors participate in the maintenance of Hoxa2 and Hoxd9 expression in mouse trunk neural crest cells. Our results suggest that RA and Wnt signaling function as environmental factors that regulate the expression of Hoxa2 and Hoxd9 in mouse neural crest cells.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Ishikawa S,Ito Kdoi
10.1007/s00441-009-0827-5subject
Has Abstractpub_date
2009-09-01 00:00:00pages
381-91issue
3eissn
0302-766Xissn
1432-0878journal_volume
337pub_type
杂志文章abstract::Rat quiescin/sulphydryl oxidase (rQSOX) introduces disulphide bridges into peptides and proteins with the reduction of molecular oxygen to hydrogen peroxide. Its occurrence has been previously highlighted in a wide range of organs by reverse transcription-polymerase chain reaction (RT-PCR) and Northern blot analyses, ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0043-x
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220036
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219841
更新日期:1975-06-27 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051132
更新日期:1998-09-01 00:00:00
abstract::Germ cells of human fetuses aged 7-13 weeks were studied. Dense fibrous material called nuage was found in the cytoplasm of human fetal germ cells. The nuage increased in frequency in the germ cells during the interval studied. In oogonia the nuage occurred much more frequently than in spermatogonia and the frequency ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00209243
更新日期:1978-11-09 00:00:00
abstract::The ultrastructure of the dermal papulae of a starfish (Asterias rubens) is consistent with a respiratory function. The present study has shown no regions specialized for excretory mechanisms. The papulae consist of an outer ectodermal epithelium of sensory, support and gland cells and a small basiepithelial nerve ple...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00229616
更新日期:1978-03-13 00:00:00
abstract::Rhabdomeres of the Drosophila melanogaster canoemisl mutant ommatidia were twisted, branched, and often fused to each other. A considerable proportion of rhabdomeres were found to have fallen below the retinal basement membrane. Electron-microscopic observations of the mutant ommatidia revealed that microvilli, the su...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004419900107
更新日期:1999-12-01 00:00:00
abstract::Although the cerebrospinal fluid-contacting neurons of the avian paraventricular organ exhibit considerable amounts of catecholamines, they show no tyrosine hydroxylase immunoreactivity. In the quail embryo, the development of these neurons has been studied using the paraformaldeyde-glutaraldeyde method for the fluore...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00307970
更新日期:1995-07-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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更新日期:2015-04-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
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更新日期:1981-01-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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abstract::The comparatively simple Caenorhabditis elegans intestine fulfills many of the complex functions of the mammalian digestive tract, liver, and fat tissues, while also having roles in pathogen defense, immunity, and longevity. In this review, we describe the structure of the C. elegans gut and how it develops from the e...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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abstract::We have previously shown that immunoneutralization of transforming growth factor-beta (TGF-beta) in the chick embryo significantly reduces programmed cell death (PCD) in peripheral neurons, spinal cord, and retina. In order to validate these results we have begun to analyze PCD in mice with targeted ablations of the T...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0761-x
更新日期:2003-07-01 00:00:00
abstract::The effects of radiotherapy on neuropeptide expression in the rat larynx were studied. Irradiation was given for five days, 6 or 8 Gray daily. Ten days after the end of irradiation, the larynx, the laryngeal nerves and different ganglia related to the larynx were dissected out from irradiated and control animals and p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00300691
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00319612
更新日期:1992-08-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-017-2650-8
更新日期:2017-10-01 00:00:00