Abstract：
:It is known that human and animal fibroblasts are able to induce the retraction of a fibrin clot. In the present study the correlation between (i) fibrin-fibroblasts during growth, (ii) the number of actin stress-lines in mouse fibroblasts during growth in culture, and (iii) the sensitivity of actin stress-lines to a powerful actin-depolymerizing factor (ADF), present in plasma and serum of humans and laboratory animals was investigated. Fibroblasts at early passages (2-4) were tested for these parameters at various intervals after seeding (24, 96, and 168 h). The number of actin stress-lines was progressively higher, while the sensitivity to ADF action was progressively lower in cells cultured from 24 to 168 h; the FCR capacity was significantly decreased at 168 h. These data suggest that cells containing weakly polymerized and/or stabilized actin are more active than those containing highly polymerized and/or stabilized actin in triggering fibroblast contraction.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Curatolo L,Chaponnier C,Donati MB,Morasca L,Gabbiani Gdoi
10.1007/BF00218485subject
Has Abstractpub_date
1982-01-01 00:00:00pages
665-73issue
3eissn
0302-766Xissn
1432-0878journal_volume
223pub_type
杂志文章abstract：:Vasodilator-stimulated phosphoprotein (VASP) and mammalian-enabled protein (MENA) share similar cellular localisation and functions (signal transduction pathways, regulation of actin cytoskeleton dynamics). Functional substitution and compensation among Ena/VASP proteins have been proposed as the reason for the absenc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0964-9
更新日期：2004-12-01 00:00:00
abstract：:Extracellular matrix (ECM) plays a dynamic role during tissue development and re-growth. Body part regeneration efficiency relies also on effective ECM remodelling and deposition. Among invertebrates, echinoderms are well known for their striking regenerative abilities since they can rapidly regenerate functioning com...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03201-0
更新日期：2020-09-01 00:00:00
abstract：:Sections of glutaraldehyde-OsO4-fixed, plastic-embedded rat incisor enamel were left untreated, stained, decalcified (1% formic acid in 10% sodium citrate), or decalcified-stained. The presence of apatite crystals was monitored with electron diffraction. After brief decalcification and staining, apatite crystals and m...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215908
更新日期：1986-01-01 00:00:00
abstract：:The localization of neuropeptide Y (NPY) and atrial natriuretic peptide (ANP) in the endothelial cells of human umbilical blood vessels was studied using the pre-embedding peroxidase-antiperoxidase (PAP) technique for electron microscopy and avidin-biotin-complex (ABC) immunostaining for endothelial cells cultured fro...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00323584
更新日期：1993-04-01 00:00:00
abstract：:Synaptic ribbons in photoreceptor cells of the goldfish pineal organ undergo significant daily changes in their length, distance from the plasma membrane, and number per unit area of pineal end-vesicle. The rhythms persist in fish exposed to constant darkness. Constant light abolishes the rhythms in length and distanc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233525
更新日期：1981-01-01 00:00:00
abstract：:A quantitative evaluation of putative amino acid neurotransmitters in sea pansy polyps by high-performance liquid chromatography indicates that the taurine content exceeds that of other amino acids by a 100-fold. The cellular source of this taurine was investigated by immunohistochemistry with two polyclonal antisera ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050800
更新日期：1997-04-01 00:00:00
abstract：:The kidney is an organ involved in cross talk with many human organs. The link between the immune system and the kidney has been studied in some detail, although data precisely elucidating their interaction are sparse, in particular with regard to the function of the kidney filter apparatus. Current research suggests ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2635-7
更新日期：2017-07-01 00:00:00
abstract：:The distribution and chemical neuroanatomy of nervous elements and certain pharmacological-physiological characteristics of the innervation of the body wall in earthworms are described. Solitary sensory bipolar cells can be found among the epithelial cells. These bipolar cells contain serotonin, tyrosine hydroxylase, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1134-4
更新日期：2005-09-01 00:00:00
abstract：:The lymphatic organization and its relationship to the vascular system in the rat small intestine was studied by scanning electron microscopy of corrosion casts and freeze-fractured tissues, and by light microscopy of injected preparations. The villus possessed 3-10 or more central lacteals depending upon the villous ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218204
更新日期：1987-05-01 00:00:00
abstract：:We compare the ultrastructure of the gerbil sublingual gland as seen after cryofixation followed by substitution with osmium tetroxide, with the more familiar appearance of material processed by glutaraldehyde-osmium chemical fixation. After primary cryofixation of fresh salivary glands, the nuclei of the mucous cells...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219075
更新日期：1987-11-01 00:00:00
abstract：:We used a combined biochemical and histocytochemical approach to study ecto-ATPase in the rat cardiac muscle. The reaction medium employed for histocytochemical detection was optimized in biochemical assays to achieve the highest enzyme activity and lowest inhibition by the capture agent used for visualization of the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900105
更新日期：1999-12-01 00:00:00
abstract：:To study the biosynthesis and intracellular migration of glycoproteins in the adrenal gland, adult mice were injected intravenously with L-(3H)-fucose and killed from 10 min to 14 days after injection. Semi-thin sections of the adrenal glands were then processed for radioautography. Incorporation of labeled fucose occ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00232246
更新日期：1979-11-01 00:00:00
abstract：:The morphology of the antennal hair-sensilla of Periplaneta americana, their distribution and frequency on the antennal flagellum have been examined by transmission- and scanning-electron microscopy. The types of sensilla were distinguished with respect to physiologically relevant criteria such as wall structure and n...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00223221
更新日期：1978-07-13 00:00:00
abstract：:Chronic tissue injury with fibrosis results in the disruption of tissue architecture, organ dysfunction and eventual organ failure. Therefore, the development of effective anti-fibrotic therapies is urgently required. During fibrogenesis, complex interplay occurs between cellular and extracellular matrix components of...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-016-2407-9
更新日期：2016-09-01 00:00:00
abstract：:In the salmon and trout aminergic cell bodies were found in the nucleus recessus lateralis (NRL) and the nucleus recessus posterioris (NRP), both of which are situated near the third ventricle. Three cell types could be distinguished. Type 1 produces a green and type 2 a yellow fluorescence. The former type probably c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219556
更新日期：1978-07-10 00:00:00
abstract：:In humans, pathogenesis in cyclosporine A (CsA)-induced gingival overgrowth (GO) includes the accumulation of extracellular matrix (ECM) constituents, viz., collagen type-1 and type-3 and proteoglycans, in subgingival connective tissue. However, whether this increase is associated with alterations of molecules pivotal...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0200-x
更新日期：2006-09-01 00:00:00
abstract：:Eosinophils are innate immune leukocytes found in relatively low numbers within the blood. Terminal effector functions of eosinophils, deriving from their capacity to release their content of tissue-destructive cationic proteins, have historically been considered primary effector mechanisms against specific parasites,...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-010-1049-6
更新日期：2011-01-01 00:00:00
abstract：:In the compound eye of the locust, Locusta, the cross-sectional area of the rhabdoms increases at "dusk" by 4.7-fold due to the rapid assembly of new microvillar membrane, and decreases at "dawn" by a corresponding amount as a result of pinocytotic shedding from the microvilli. The rhabdoms at night have more and long...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214807
更新日期：1982-01-01 00:00:00
abstract：:The distribution pattern of adrenergic fibres innervating the ocular choroid membrane of the chicken was studied by means of fluorescence and electron microscopy. In addition, the origin of these fibres was investigated after superior cervical ganglionectomy. Adrenergic axons reach the choroid, partly forming the peri...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213222
更新日期：1982-01-01 00:00:00
abstract：:Accumulating evidence suggests that the sympathetic nervous system modulates inflammatory responses and bone remodeling. We have studied the effects of sympathectomy and orthodontic tooth movement (OTM) on root resorption, immunocompetent cell recruitment, neuropeptide, neurokinin-1 receptor (NK1-R), and interleukin 6...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0753-x
更新日期：2003-08-01 00:00:00
abstract：:Neurons projecting from the brain to the pineal gland via the pineal stalk were investigated in the golden hamster with the use of the retrograde horseradish-peroxidase tracing method both in vivo and in vitro. Labelled perikarya were observed in the medial and lateral habenular nuclei as well as in the posterior comm...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216557
更新日期：1987-01-01 00:00:00
abstract：:Sex pheromones orient male moths toward conspecific female moths; the presence of visual information modulates this behavior. In the current study, we explore candidate neuronal pathways for the interaction between vision and the locomotor signal for pheromone orientation. We describe the connectivity between visual n...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2892-0
更新日期：2018-12-01 00:00:00
abstract：:During the reproductive period of the male stickleback, structural and functional changes of the kidney take place, both in the glomeruli and in the renal tubule cells. The structural changes in the glomeruli involve almost all glomerular components and point to a reduction of the glomerular filtration rate. The purpo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210146
更新日期：1981-01-01 00:00:00
abstract：:The analysis of myenteric neurons is becoming increasingly important for the assessment of enteric nervous system injury and degeneration occurring in motor disorders of the gut. Limited information is presently available on the quantitative estimation of myenteric neurons and glial cells in paraffin-embedded colonic ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0770-5
更新日期：2009-05-01 00:00:00
abstract：:Many efforts have been made to improve the diagnostic tools used to identify and to estimate the progress of ganglion cell and nerve fibre degeneration in glaucoma. Imaging by optical coherence tomography and measurements of the dimensions of the optic nerve head and the nerve fibre layer in central retinal areas is c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1602-1
更新日期：2013-08-01 00:00:00
abstract：:Neural lobes of control and "Jimpy" mice were examined electron microscopically. The ultrastructure and incidence of pituicytes was examined following reports of reductions in astrocyte and oligodendrocyte populations in areas of the CNS of Jimpy mice. The failure to demonstrate any modification of structure or number...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220162
更新日期：1976-03-05 00:00:00
abstract：:In the developing mammalian nervous system, common progenitors integrate both cell extrinsic and intrinsic regulatory programs to produce distinct neuronal and glial cell types as development proceeds. This spatiotemporal restriction of neural progenitor differentiation is enforced, in part, by the dynamic reorganizat...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-2011-9
更新日期：2015-01-01 00:00:00
abstract：:Neuroblastoma, a malignancy of the developing peripheral nervous system that affects infants and young children, is a complex genetic disease. Over the past two decades, significant progress has been made toward understanding the genetic determinants that predispose to this often lethal childhood cancer. Approximately...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-018-2820-3
更新日期：2018-05-01 00:00:00
abstract：:M cells in Peyer's patch epithelium conduct transepithelial transport of luminal antigens to cells of the mucosal immune system. To determine the distribution of specific lectin-binding sites on luminal membranes of living M cells and to follow the transport route of membrane-bound molecules, lectin-ferritin conjugate...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215747
更新日期：1987-03-01 00:00:00
abstract：:The effect of pilocarpine and food uptake on the rate of incorporation of [3H]-leucine in vivo was measured by means of quantitative radioautography in three exocrine cells of the rat: the acinar and the granular duct cells of the submandibular and the acinar cells of the parotid gland. The three cell types react diff...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219936
更新日期：1975-12-18 00:00:00
