Testosterone-dependent changes in vivo and in vitro in the structure of the renal glomeruli of the teleost Gasterosteus aculeatus L.

Abstract:

:During the reproductive period of the male stickleback, structural and functional changes of the kidney take place, both in the glomeruli and in the renal tubule cells. The structural changes in the glomeruli involve almost all glomerular components and point to a reduction of the glomerular filtration rate. The purpose of this study was to investigate whether these changes are controlled by testosterone, indirectly or directly. In vivo experiments demonstrated that exposures of immature castrates for 8 days to methyltestosterone leads to activation of mesangial cells and podocytes, to slight expansion of mesangial matrix and slight thickening of basal lamina. Observations on cultured renal tissue showed that two androgens, 11-ketotestosterone and methyltestosterone, are also able to stimulate the secretory activity of podocytes and mesangial cells in vitro. The results therefore indicate, that most glomerular changes in male sticklebacks during the reproductive season are directly effected by testosterone.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

de Ruiter AJ

doi

10.1007/BF00210146

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

253-66

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

219

pub_type

杂志文章
  • Peritrophic matrix of Phlebotomus duboscqi and its kinetics during Leishmania major development.

    abstract::Light microscopy of native preparations, histology, and electron microscopy have revealed that Phlebotomus duboscqi belongs to a class of sand fly species with prompt development of the peritrophic matrix (PM). Secretion of electron-lucent fibrils, presumably chitin, starts immediately after the ingestion of a blood m...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-009-0802-1

    authors: Sádlová J,Volf P

    更新日期:2009-08-01 00:00:00

  • Renewal of the ciliary axoneme in cone outer segments of the retina of Xenopus laevis.

    abstract::The ciliary axoneme in photoreceptors from the retina of Xenopus laevis was examined by immunofluorescent staining of tubulin throughout the light/dark cycle. The immunofluorescent axoneme extended along only part of the length of rod outer segments but the entire length of cone outer segments. Both the cone axoneme a...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410050632

    authors: Eckmiller MS

    更新日期:1996-07-01 00:00:00

  • The major ganglion in the pelvic plexus of the male rat: a histochemical and ultrastructural study.

    abstract::To further evaluate the role of autonomic ganglia in the regulation of pelvic visceral activity, the neural elements in the major pelvic ganglion of the male rat have been studied with histochemixal and electron microscopic techniques. The principal findings are that the ganglion is composed of cholinergic and adrener...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00231994

    authors: Dail WG,Evan AP,Eason HR

    更新日期:1975-05-27 00:00:00

  • Fine structure of the malaria parasite Plasmodium falciparum in human hepatocytes in vitro.

    abstract::Recent advances in the ability to culture the hepatic forms of mammalian malaria parasites, particularly of the important human pathogen Plasmodium falciparum have provided novel opportunities to study the ultrastructural organisation of the parasite in its natural host cell the human hepatocyte. In this electron-micr...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219210

    authors: Meis JF,Rijntjes PJ,Verhave JP,Ponnudurai T,Hollingdale MR,Smith JE,Sinden RE,Jap PH,Meuwissen JH,Yap SH

    更新日期:1986-01-01 00:00:00

  • Combined effect of ligament stem cells and umbilical-cord-blood-derived CD34+ cells on ligament healing.

    abstract::Transplantation of ligament-tissue-derived stem cells has become a promising approach in the repair of injured ligament. Neovascularization plays an important role in ligament healing and remodeling. Recently, human umbilical-cord-blood-derived CD34+ cells have been reported to contribute to neoangiogenesis. Therefore...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-015-2250-4

    authors: Jiang D,Yang S,Gao P,Zhang Y,Guo T,Lin H,Geng H

    更新日期:2015-12-01 00:00:00

  • Demonstration of a somatostatin-like activity in retinal cells of the rat.

    abstract::A somatostatin-like substance is demonstrated by light microscopic immunohistochemistry (PAP-method) in perikarya and cell processes of the retina of adult and infant rats. These perikarya are identified according to their size, arrangement and distribution. Each of the first two neuronal orders (receptors, bipolar ce...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00235169

    authors: Kirsch B,Leonhardt H

    更新日期:1979-01-01 00:00:00

  • Ultrastructural changes in the spiral limbus associated with carboplatin-induced ablation of inner hair cells.

    abstract::Four months after the selective ablation of inner hair cells by carboplatin, the interdental cell epithelium exhibited dilated intercellular spaces and cytosolic vacuoles not seen in controls. In addition, the wide, often electron-lucent phalanges observed in the interdental cells of the normal chinchilla collapsed in...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410000253

    authors: Spicer SS,Salvi RJ,Schulte BA

    更新日期:2000-10-01 00:00:00

  • Respiratory epithelial cells in innate immunity to influenza virus infection.

    abstract::Infection by influenza virus leads to respiratory failure characterized by acute lung injury associated with alveolar edema, necrotizing bronchiolitis, and excessive bleeding. Severe reactions to infection that lead to hospitalizations and/or death are frequently attributed to an exuberant host response, with excessiv...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-010-1043-z

    authors: Sanders CJ,Doherty PC,Thomas PG

    更新日期:2011-01-01 00:00:00

  • Molecular studies of BKCa channels in intracranial arteries: presence and localization.

    abstract::Large conductance calcium-activated potassium channels (BK(ca)) are crucial for the regulation of cerebral vascular basal tone and might be involved in cerebral vasodilation relevant to migraine and stroke. We studied the differential gene expression of mRNA transcript levels and protein expression of the BK(Ca) chann...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-008-0701-x

    authors: Wulf H,Hay-Schmidt A,Poulsen AN,Klaerke DA,Olesen J,Jansen-Olesen I

    更新日期:2008-12-01 00:00:00

  • Effects of colchicine on the ultrastructure of mouse taste buds.

    abstract::Effect of colchicine on the ultrastructure of taste bud cells was studied in the mouse. In untreated mice microtubules were abundant throughout the entire cytoplasm of type-III cells, but only in the apical cytoplasm of type-I cells. After 2 h of colchicine treatment, no microtubules were observed in any taste bud cel...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00214555

    authors: Takeda M,Suzuki Y,Shishido Y

    更新日期:1985-01-01 00:00:00

  • Serum-free cryopreservation of porcine hepatocytes.

    abstract::The use of porcine hepatocytes in xenotransplantation, bioartificial liver support or pharmacological approaches demands serum-free cryopreservation protocols yielding high quality, viable, functional hepatocytes. Here, primary porcine hepatocytes were frozen without serum in liquid nitrogen by the use of a computer-a...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-004-0894-6

    authors: Müller P,Aurich H,Wenkel R,Schäffner I,Wolff I,Walldorf J,Fleig WE,Christ B

    更新日期:2004-07-01 00:00:00

  • Fine structure of complex ocelli of a cubomedusan, Tamoya bursaria Haeckel.

    abstract::The retina of the distal and proximal lens-bearing complex ocelli are composed of pigmented sensory cells and long pigmented cells. A ciliary sheath from each sensory cell, together with the processes of long pigmented cells, extends through the vitreous layer as far as the capsule that envelops the lens. Each ciliary...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219415

    authors: Yamasu T,Yoshida M

    更新日期:1976-07-30 00:00:00

  • Immunocytological characterization of the expression of cell adhesion molecule L1 during early innervation of mouse otocysts.

    abstract::Doubts exist as to whether afferent nerve fibers exert a neurotrophic effect on the differentiation of sensory cells in the developing vestibular neuroepithelium. To determine whether innervation of hair cells precedes their differentiation, we have used the L1 adhesion molecule as a marker for axons. The detection of...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00229069

    authors: Mbiene JP,Dechesne CJ,Schachner M,Sans A

    更新日期:1989-01-01 00:00:00

  • Expression of Slc35f1 in the murine brain.

    abstract::The solute carrier (SLC) group of membrane transport proteins includes about 400 members organized into more than 50 families. The SLC family that comprises nucleoside-sugar transporters is referred to as SLC35. One of the members of this family is SLC35F1. The function of SLC35F1 is still unknown; however, recent stu...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-019-03008-8

    authors: Farenholtz J,Artelt N,Blumenthal A,Endlich K,Kroemer HK,Endlich N,von Bohlen Und Halbach O

    更新日期:2019-08-01 00:00:00

  • Selective visualisation of neuroepithelial bodies in vibratome slices of living lung by 4-Di-2-ASP in various animal species.

    abstract::Pulmonary neuroepithelial bodies (NEBs) are extensively innervated organoid groups of neuroendocrine cells that lie in the epithelium of intrapulmonary airways. Our present understanding of the morphology of NEBs is comprehensive, but direct physiological studies have so far been challenging because the extremely diff...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-005-1111-y

    authors: Pintelon I,De Proost I,Brouns I,Van Herck H,Van Genechten J,Van Meir F,Timmermans JP,Adriaensen D

    更新日期:2005-07-01 00:00:00

  • Human and rodent bone marrow mesenchymal stem cells that express primitive stem cell markers can be directly enriched by using the CD49a molecule.

    abstract::Bone marrow (BM) from human and rodent species contains a population of multipotential cells referred to as mesenchymal stem cells (MSCs). Currently, MSCs are isolated indirectly by using a culture step and then the generation of fibroblast colony-forming units (CFU-fs). Unprocessed or native BM MSCs have not yet been...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-006-0292-3

    authors: Gindraux F,Selmani Z,Obert L,Davani S,Tiberghien P,Hervé P,Deschaseaux F

    更新日期:2007-03-01 00:00:00

  • The hypothalamic magnocellular system in the domestic fowl. A golgi and electron microscopic study.

    abstract::In the rostral hypothalamus of the domestic fowl, the magnocellular neurosecretory nuclei show a peculiar differentiation. Golgi studies of the supraoptic and paraventricular nuclei of the fowl reveal at least two major cell types: 1) large multipolar neurons, and 2) small interneurons. Golgi impregnations provide a d...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00236253

    authors: Viglietti-Panzica C,Panzica GC

    更新日期:1981-01-01 00:00:00

  • Visualization of interstitial cells of Cajal in the mouse colon by vital staining.

    abstract::Interstitial cells of Cajal (ICCs) are believed to be a major element in generating the spontaneous rhythm of the gastrointestinal tract. A prominent problem in the study of these cells has been the difficulty in observing them in intact tissues. We used the lipophilic dye DiI to stain ICCs in the submucosal-circular ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051058

    authors: Hanani M,Louzon V,Miller SM,Faussone-Pellegrini MS

    更新日期:1998-05-01 00:00:00

  • Movement of villi induces endocytosis of NK1 receptors in myenteric neurons from guinea-pig ileum.

    abstract::Agitation of villi evokes reflexes that affect the motility of the guinea-pig small intestine. NK1 receptor endocytosis was used to investigate the possible involvement of tachykinins acting on neuronal NK1 receptors in these reflexes. Segments of guinea-pig ileum were incubated at 37 degrees C in Krebs physiological ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s004410051032

    authors: Southwell BR,Woodman HL,Royal SJ,Furness JB

    更新日期:1998-04-01 00:00:00

  • Predicting response to cancer chemotherapy: the role of p53.

    abstract::Loss of wild-type p53 activity is thought to be a major predictor of failure to respond to radiotherapy and chemotherapy in various human cancers. This assumption is largely based on some cell-death studies in p53-knockout mice and on correlations of p53 status assessed by immunochemistry or single-strand conformation...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s004410051072

    authors: Weller M

    更新日期:1998-06-01 00:00:00

  • Bone marrow-derived versus adipose-derived stem cells in wound healing: value and route of administration.

    abstract::The stem cells with their distinct ability of self-renewal and differentiation are considered an innovation in wound healing. However, there is lack of studies comparing the differential effect of the type and administration route of stem cells in the wound healing context. Thus, the current study has been designed to...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/s00441-018-2879-x

    authors: Aboulhoda BE,Abd El Fattah S

    更新日期:2018-11-01 00:00:00

  • Mesothelial intercellular junctions and pathways.

    abstract::Freeze-etch preparations of mesothelial cells taken from the peritoneum of mouse reveal the presence of vesicles invaginating the apical and the basal cell surfaces. These vesicles are scarcely seen within the cytoplasm. Long tortuous tubular profiles extend for considerable distance within the cytoplasm and are frequ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219271

    authors: Baradi AF,Rayns DG

    更新日期:1976-10-01 00:00:00

  • The morphology and cell culture of the striated musculature of the rat azygos vein.

    abstract::The azygos vein of the rat can be divided into three regions: The proximal cardiac region, where the wall is composed of two and sometimes three layers of cardiac muscle and a thin discontinuous layer of smooth muscle cells. Vascular casts of this region demonstrate layers of capillaries closely following the orientat...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00221867

    authors: Cullinan V,Campbell JH,Mosse PR,Campbell GR

    更新日期:1986-01-01 00:00:00

  • In vitro differentiation of hypothalamic magnocellular neurons of guinea pigs.

    abstract::The development of neurophysin-oxytocin and neurophysin-vasopressin containing neurons of the guinea pig was studied in vitro. Supraoptic (SO) and paraventricular (PV) nuclei were explanted from guinea pig foetuses at the 40th day of gestation and cultured in Maximov slides for nearly fifty days. The cultures were obs...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00233269

    authors: Marson AM,Privat A

    更新日期:1979-01-01 00:00:00

  • Neuronal galanin is widely distributed in the chicken respiratory tract and coexists with multiple neuropeptides.

    abstract::The mammalian airways are known to be richly innervated by several types of peptide-containing nerve fibers. Galanin-containing fibers are, however, comparatively few. The results of the present immunocytochemical study indicate that the chicken airways receive a notably dense supply of galanin-storing fibers. Other m...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00224722

    authors: Luts A,Uddman R,Sundler F

    更新日期:1989-04-01 00:00:00

  • Genetic susceptibility to neuroblastoma: current knowledge and future directions.

    abstract::Neuroblastoma, a malignancy of the developing peripheral nervous system that affects infants and young children, is a complex genetic disease. Over the past two decades, significant progress has been made toward understanding the genetic determinants that predispose to this often lethal childhood cancer. Approximately...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审

    doi:10.1007/s00441-018-2820-3

    authors: Ritenour LE,Randall MP,Bosse KR,Diskin SJ

    更新日期:2018-05-01 00:00:00

  • Immunohistochemical study on the morphology of enterochromaffin cells in the human fundic mucosa.

    abstract::The morphology of enterochromaffin (EC) cells in the human fundic mucosa was investigated at the light-microscopic level by means of the unlabeled peroxidase anti-peroxidase method, with the use of a highly specific anti-serotonin serum. EC-cells in the human fundic mucosa were sparsely distributed below the neck port...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00226973

    authors: Inokuchi H,Kawai K,Takeuchi Y,Sano Y

    更新日期:1984-01-01 00:00:00

  • The nature of the clear zone around microtubules.

    abstract::The clear zones seen around microtubules in transverse sections of nutritive tubes vary in size depending on whether a microtubule is bordered by ribosomes or by another microtubule. We consider that such a finding is not consistent with the current view, that the clear zone is maintained by microtubule-associated mat...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00204791

    authors: Stebbings H,Hunt C

    更新日期:1982-01-01 00:00:00

  • Export of protein from the osteoclast as studied by electron microscopic autoradiography.

    abstract::The present electron microscopic autoradiographic study includes a quantitative analysis of osteoclasts in vitro using tritiated leucin as a protein tracer. A significant increase in the grain density over the ruffled border and the underlying resportion zone was demonstrated two hours post pulse whereas the grain den...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00219726

    authors: Lucht U,Norgaard JO

    更新日期:1976-04-28 00:00:00

  • Ultrastructural characterisation of vasopressinergic terminals in the lateral septum of murine brains by use of monoclonal anti-neurophysins.

    abstract::Synapses in the lateral septum of the murine brain have been investigated by ultrastructural immunocytochemistry, using monoclonal anti-neurophysins in both immunoperoxidase and immunogold techniques. In the region shown by light microscopy to be rich in vasopressinergic innervation, synaptic boutons containing approx...

    journal_title:Cell and tissue research

    pub_type: 杂志文章

    doi:10.1007/BF00215524

    authors: Shaw FD,Castel M,Morris JF

    更新日期:1987-08-01 00:00:00