Abstract：
:Effect of colchicine on the ultrastructure of taste bud cells was studied in the mouse. In untreated mice microtubules were abundant throughout the entire cytoplasm of type-III cells, but only in the apical cytoplasm of type-I cells. After 2 h of colchicine treatment, no microtubules were observed in any taste bud cells; dense secretory granules in the apical cytoplasm of type-I cells mostly disappeared, and instead, numerous phagosomes appeared. It is suggested that colchicine causes an interruption of the transport of the secretory granules in type-I cells from the Golgi apparatus to the membrane of the apical surface, from which release occurs. In type-III cells, after 4 or 5 h of treatment, dense-cored vesicles scattered throughout the cytoplasm tended to increase in number; they were often observed to accumulate in the vicinity of the Golgi apparatus. Five hours after treatment with 5-hydroxy-L-tryptophan (5-HTP) following colchicine pretreatment, monoamine specific fluorescent cells and vesicles with highly electron-dense cores of type-III cells were still present. On the other hand, 5 h after 5-HTP treatment alone both fluorescent cells and vesicles with highly electron-dense cores had already disappeared. These observations suggest that the treatment with colchicine interrupts the transport of dense-cored vesicles of type-III cells to synaptic areas, in which those vesicles are presumed to discharge the neurotransmitter substance.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Takeda M,Suzuki Y,Shishido Ydoi
10.1007/BF00214555subject
Has Abstractpub_date
1985-01-01 00:00:00pages
409-16issue
2eissn
0302-766Xissn
1432-0878journal_volume
242pub_type
杂志文章abstract：:A tumor model system of clones of myeloproliferative sarcoma virus (MPV)-transformed rat fibroblasts (NRK) with different growth properties and metastatic potential was studied. The relationship between metastatic behavior and composition of carbohydrate-binding proteins (lectins) was analyzed by affinity chromatograp...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215191
更新日期：1986-01-01 00:00:00
abstract：:In the salmon and trout aminergic cell bodies were found in the nucleus recessus lateralis (NRL) and the nucleus recessus posterioris (NRP), both of which are situated near the third ventricle. Three cell types could be distinguished. Type 1 produces a green and type 2 a yellow fluorescence. The former type probably c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219556
更新日期：1978-07-10 00:00:00
abstract：:We have examined radioautographically the protein synthetic and secretory activity of differentiating odontoblasts and ameloblasts, exposed for 9 h in vitro to various concentrations of colchicine in the presence of 3H-proline. Colchicine impairs the cytodifferentiation of the dental epithelium into ameloblasts and of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216651
更新日期：1988-06-01 00:00:00
abstract：:The immunocytochemical localization of bovine oviduct-specific glycoproteins was investigated by light and electron microscopy. Using monoclonal antibodies (MAbs) specific for bovine oviductal glycoproteins, 3 regions (fimbriae, ampulla, and isthmus) of the epithelium in the bovine oviduct we studied during the follic...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00327983
更新日期：1993-10-01 00:00:00
abstract：:Unfertilized eggs commonly lack centrioles, which are usually provided by the male gamete at fertilization, and are unable to assemble functional reproducing centrosomes. However, some insect species lay eggs that develop to adulthood without a contribution from sperm. We report that the oocyte of the parthenogenetic ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0253-x
更新日期：2006-12-01 00:00:00
abstract：:The neural circuit that controls the hearts in the leech comprises an ensemble of synaptically interconnected cardiac motor neurons (HE cells) and cardiac interneurons (HN cells). Both the HE cells and the HN cells constitute segmentally homologous sets. We have investigated the structure of these neurons by iontophor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00235152
更新日期：1981-01-01 00:00:00
abstract：:Renovascular hypertension (RVH) is a progressive disease, leading to chronic kidney disease when untreated and no specific treatment is available. Therefore, development of new therapeutic modalities is imperative. RVH is triggered by renal artery stenosis and subsequent renin-angiotensin-aldosterone system activation...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-017-2602-3
更新日期：2017-08-01 00:00:00
abstract：:Neural lobes of rats subjected to dehydration by drinking 2% saline for four days were examined electron microscopically and compared to untreated controls. The ultrastructure of the blood vessels and the tissues surrounding them were examined and it was found that, although few exocytotic figures could be seen in eit...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221710
更新日期：1975-06-24 00:00:00
abstract：:The carotid body is a peripheral chemoreceptor that detects decreases in arterial pO2 and subsequently activates the carotid sinus nerve. The hypoxia-evoked activity of the carotid sinus nerve has been suggested to be modulated by glutamate. In the present study, we investigate the immunohistochemical localization of ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-1921-x
更新日期：2014-10-01 00:00:00
abstract：:Angiogenesis, the growth of new blood vessels, is required for a variety of normal proliferative processes. Furthermore, angiogenesis is well established as also playing an important role in neoplastic growth and metastasis. Numerous regulators of angiogenesis have been identified and characterized over the last few d...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-008-0675-8
更新日期：2009-01-01 00:00:00
abstract：:The fine structure of synapses, their distribution and arrangement in the ventral nerve cord of Peripatoides leuckarti (phylum Onychophora) is described. The asymmetric synaptic junctions show a well developed synaptic cleft (300 A) and pre- and subsynaptic electron dense apposition. They frequently show an array of p...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224940
更新日期：1978-01-31 00:00:00
abstract：:Granular hormone-producing cells and agranular cells (stellate cells, including giant and pericavitary cells) were electron microscopically studied in the hypophysis of the small spotted dogfish (Scyllium canicula) up to several months after hatching. Comparisons of results obtained in embryos, newly-hatched fish and ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221607
更新日期：1978-10-06 00:00:00
abstract：:The innervation of the rat anococcygeus muscle has been investigated ultrastructurally following fixation with a modified chromaffin reaction for the demonstration of biogenic amines (Tranzer and Richards, 1976). Three types of nerve profiles were revealed: (1) 60-70% of the profiles are adrenergic; (2) less than 5% o...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236418
更新日期：1979-08-01 00:00:00
abstract：:Using histochemical, immunohistochemical and biochemical techniques, noradrenaline-, neuropeptide Y-, vasoactive intestinal polypeptide-, substance P- and calcitonin gene-related peptide-containing nerve fibres were studied in the uterine artery of virgin, progesterone-treated and pregnant guinea-pigs. Morphological c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF01740777
更新日期：1990-03-01 00:00:00
abstract：:The tyrosine kinase proteins (Trk), encoded by the trk family of proto-oncogenes, mediate, in mammals, the action of neurotrophins, a family of growth factors acting on the development and maintenance of the nervous system. Neurotrophins and their specific receptors, TrkA, TrkB and TrkC, seem to be phylogenetically we...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000342
更新日期：2001-03-01 00:00:00
abstract：:Box jellyfish have the most elaborate sensory system and behavioural repertoire of all cnidarians. Sensory input largely comes from 24 eyes situated on four club-shaped sensory structures, the rhopalia, and behaviour includes obstacle avoidance, light shaft attractance and mating. To process the sensory input and conv...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0393-7
更新日期：2007-07-01 00:00:00
abstract：:Correlations between the presence of surface coat and immobilization antigen of Paramecium tetraurelia were studied. Supravital, partial removal of the surface coat resulted in accelerated response of monobacterially and axenically grown cells to the homologous antiserum. Ciliates pretreated with trypsin or pronase (0...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219984
更新日期：1977-07-11 00:00:00
abstract：:Changes in intestinal function, notably impaired transit, following ischemia/reperfusion (I/R) injury are likely to derive, at least in part, from damage to the enteric nervous system. Currently, there is a lack of quantitative data and methods on which to base quantitation of changes that occur in enteric neurons. In...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-1126-x
更新日期：2011-04-01 00:00:00
abstract：:More than twenty different enzyme activities of fractions containing dictyosome-like structures (DLS) as a dominant cell component were monitored. Plasma membrane vesicles were a major contaminant of the DLS fractions, which, presumably as a consequence, were enriched somewhat in plasma membrane markers. The lysosomal...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217555
更新日期：1985-01-01 00:00:00
abstract：:Evidence has already been adduced suggesting that an increase in microtubular number occurs in the tractus hypophyseus of rats stressed by the administration of hypertonic saline, and of rats with congenital diabetes insipidus (CDI). Since the tractus hypophyseus in these animals shows high secretory activity, it seem...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219611
更新日期：1976-06-28 00:00:00
abstract：:Adenosine 5'-triphosphate is known to function as a potent extracellular messenger, producing its effects via a distinct family of cell surface receptors. Different receptor subtypes have been shown to modulate different cellular functions such as proliferation, differentiation and apoptosis. We have investigated the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1149-x
更新日期：2005-09-01 00:00:00
abstract：:The occurrence of neurons possessing high-affinity uptake sites for GABA was studied in the myenteric plexus of the guinea-pig ileum, caecum, and proximal and distal colon, the rat proximal colon, and the chicken gizzard with the use of 3H-GABA and autoradiography. Experiments were carried out on plexuses that had bee...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217417
更新日期：1983-01-01 00:00:00
abstract：:Hypothalamic slices containing the lateral hypothalamic area (LHA) were prepared from 6- to 8-day-old rats and maintained in stationary culture for up to 35 days in order to analyse how well the melanin-concentrating hormone (MCH) neurons survived. As previously reported for other brain areas, this method yielded a lo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051330
更新日期：1999-07-01 00:00:00
abstract：:We have recently examined the electrophysiology and ultrastructure of approximately 100 tactile spines from the metathoracic legs of adult cockroaches. In only one animal the single sensory neuron that innervates the spine was replaced with a pair of apparently identical neurons which we believe were both functional. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216522
更新日期：1984-01-01 00:00:00
abstract：:The pineal gland structure and ultrastructure in the Northern (Blarina brevicauda) and Southern short-tailed shrew (Blarina carolinensis) are described by light and electron microscopy. Results observed were similar to other mammals of Insectivora described previously, specifically, the hedgehog (Erinaceus europaeus) ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2897-8
更新日期：2018-12-01 00:00:00
abstract：:The ultrastructural organization of the axons of retinula cells of the eye of the wax moth Galleria mellonella are described. The axons traverse an appreciable distance between the basement membrane of the retina and the lamina ganglionaris of the optic lobe of the brain. The optic tract was reconstructed from serial ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00232837
更新日期：1976-11-18 00:00:00
abstract：:The vascularization of the hypothalamo-adenohypophysial region of the toad Bufo bufo (L.) (Amphibia, Anura) was studied by means of light- and scanning electron microscopy. Special attention was given to the portal vascular system of the median eminence and the pars distalis. Course and arrangement of these vessels ar...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00223268
更新日期：1975-09-16 00:00:00
abstract：:Intercellular junctions in the young mouse ovary were examined by electron microscopy utilizing freeze-fracture and thin-sectioning techniques. Projections from the granulosa cells adjacent to the oocyte (GI) traverse the zona pellucida and form small gap junctions on the oocyte surface. On the P-face of these cells, ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216881
更新日期：1982-01-01 00:00:00
abstract：:The development of the heterophil granulocytes in the bone marrow of the guinea pig is described. During the maturation of these cells, three types of granule are formed, not only the azurophil and specific granules already described in other mammals but also a third type of granule referred to here as the nucleated g...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220388
更新日期：1978-11-20 00:00:00
abstract：:Ossification of calvariae from day-21 rat fetuses was reinvestigated by electron microscopy using different fixation techniques (glutaraldehyde/OsO4, tannic acid, ruthenium red, K-pyroantimonate). An osteoid layer with scattered mineral deposits was found at the mineralization front. Directly beyond this layer, a shee...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318693
更新日期：1992-01-01 00:00:00
