Distribution of neurons with high-affinity uptake sites for GABA in the myenteric plexus of the guniea-pig, rat and chicken.

Abstract:

:The occurrence of neurons possessing high-affinity uptake sites for GABA was studied in the myenteric plexus of the guinea-pig ileum, caecum, and proximal and distal colon, the rat proximal colon, and the chicken gizzard with the use of 3H-GABA and autoradiography. Experiments were carried out on plexuses that had been freshly isolated from the gut wall or on isolated plexuses that had been maintained as explant cultures for 7 to 14 days. Scattered neurons selectively labelled with 3H-GABA were found in the myenteric plexuses from all the areas examined. The results suggest that GABAergic neurons are widely distributed in the enteric nervous system.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Saffrey MJ,Marcus N,Jessen KR,Burnstock G

doi

10.1007/BF00217417

subject

Has Abstract

pub_date

1983-01-01 00:00:00

pages

231-5

issue

1

eissn

0302-766X

issn

1432-0878

journal_volume

234

pub_type

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