Abstract：
:The evolution of aquaporin-5 (AQP5) expression during postnatal development has not been defined in the sweat gland. Previous studies have suggested that AQP isoforms in several peripheral targets are regulated by a neural mechanism. We have examined, in rat sweat glands, the expression of AQP5 during postnatal development and the effects of denervation on AQP5 expression. Both AQP5 mRNA and protein begin to be expressed at postnatal day 10, before sweat-secretory responsiveness first appears; this expression coincides with the occurrence of vasoactive intestinal peptide (VIP) immunoreactivity. Early noradrenergic and later cholinergic interaction between sweat glands and their innervation are disrupted by neonatal chemical sympathectomy or postnatal severance of the sciatic nerve. Examination of such denervated developing rats has shown that secretory responsiveness fails to arise later in the adults, and AQP5 immunostaining increases in the denervated glands, whereas gland morphogenesis and the occurrence of AQP5 expression proceed normally. Immunobloting has revealed an increase of AQP5 abundance after the denervated mature glands lose their secretory ability. These findings suggest that AQP5 protein is necessary for sweat secretion, and that the expression of AQP5 in rat sweat glands is independent of sympathetic innervation. Our data also indicate that factor(s) regulating the normal morphological development of sweat gland might be responsible for controlling AQP5 expression.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Ma L,Huang YG,He H,Deng YC,Zhang HF,Che HL,Tian JY,Zhao Gdoi
10.1007/s00441-007-0399-1subject
Has Abstractpub_date
2007-07-01 00:00:00pages
25-33issue
1eissn
0302-766Xissn
1432-0878journal_volume
329pub_type
杂志文章abstract：:This study explores the molecular composition of the tight junction (TJ) in human term placenta from normal women and from patients with preeclampsia, a hypertensive disorder of pregnancy. Maternal endothelial dysfunction is a critical characteristic of preeclampsia; hence, we have analyzed its impact on placental ves...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-0135-7
更新日期：2006-06-01 00:00:00
abstract：:The reaction of nerve endings in the median eminence of the rat to zinc iodide-osmium tetroxide (ZIO) staining was examined electron microscopically under normal and experimental conditions. The experimental condition of catecholamine exhaustion in the nerve endings was induced by the administration of H44/68 and rese...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220316
更新日期：1976-10-13 00:00:00
abstract：:The endothelial layer of blood vessels controls the passage of cells and solutes from the blood into the surrounding tissue. Crucial for this regulation is the integrity of endothelial cell-cell junctions. Various molecular mechanisms control junctional integrity of the endothelial layer including GTPases, modulation ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-1812-1
更新日期：2014-03-01 00:00:00
abstract：:The distribution of luteinizing hormone-releasing hormone (LHRH) was studied in the rat and mouse brain by means of light and electron microscopic immunohistochemistry using the peroxidase-antiperoxidase method. An immunoreactive product to LHRH antiserum was found near the blood vessels of the vascular organ of the l...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233914
更新日期：1979-03-19 00:00:00
abstract：:The cellular localization of the enzymes tyrosine hydroxylase (TH), aromatic amino-acid decarboxylase (or dopa decarboxylase, DDC), dopamine beta-hydroxylase (DBH) and phenylethanolamine N-methyltransferase (PNMT) in the adrenal medulla of adult rats and rat fetuses (14th, 17th, 18th, 19th and 21st day) was examined. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236882
更新日期：1979-08-03 00:00:00
abstract：:By using an antiserum raised against a crustacean beta-pigment-dispersing hormone (PDH), the distribution and chemical neuroanatomy of PDH-like immunoreactive neurons was investigated in the central nervous system of the gastropod snails, Helix pomatia and Lymnaea stagnalis. The number of immunoreactive cells in the H...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051240
更新日期：1999-02-01 00:00:00
abstract：:The pigmentary system of the planaria, Dugesia gonocephala s.l. (Platyhelminthes, Turbellaria, Tricladida), consists of granules contained in chromatophore cells distributed in the parenchyma tissue. The administration of MSH release-inhibiting Factor (M.I.F.) leads to an easily observable general decolouration of the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236132
更新日期：1979-06-27 00:00:00
abstract：:Glutamate is the major excitatory neurotransmitter of the mammalian retina and glutamate uptake is essential for normal transmission at glutamatergic synapses. The reverse transcriptase-polymerase chain reaction (RT-PCR) has revealed the presence of three different high-affinity glutamate transporters in the rat retin...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050976
更新日期：1998-01-01 00:00:00
abstract：:Besides its function at cholinergic synapses, acetylcholinesterase (AChE) exerts structural functions on neural differentiation, independent of its enzymatic activity. To elucidate such functions, we have previously heterologously expressed AChE in histotypic retinal reaggregates, revealing strong effects on their his...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410100444
更新日期：2001-11-01 00:00:00
abstract：:We have examined the cortex of the teleost (Brachydanio rerio) egg before and during exocytosis of cortical granules by scanning, transmission, and freeze-fracture electron microscopy. In the unactivated egg, the P-face of the plasma membrane exhibits a random distribution of intramembranous particles, showing a densi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00398079
更新日期：1991-08-01 00:00:00
abstract：:In Streetsia challengeri left and right eyes have fused and become a single cylindrical photoreceptor, which occupies the basal half of a forward directed head projection. This unusual compound eye consists of approximately 2500 ommatidia, which are arranged in such a way that the animal has almost circumferential vis...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00225542
更新日期：1978-01-17 00:00:00
abstract：:In the small intestine of the pig, neuromedin U (NMU)-immunoreactivity was mainly confined to the nerve plexus of the inner submucosal and mucosal regions. After colchicine treatment, a high number of immunoreactive nerve cell bodies was observed in the plexus submucosus internus (Meissner), whereas only a low number ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00239453
更新日期：1989-11-01 00:00:00
abstract：:Maternal immunoglobulin-G (IgG) is known to be transported across the placental syncytiotrophoblast during the period when the human fetus is incapable of manufacturing these defensive molecules. In this study we investigated the possible role of the amniochorion, that surrounds the amniotic cavity in which the fetus ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00583405
更新日期：1995-08-01 00:00:00
abstract：:Neural stem and progenitor cells produce one of the most remarkable organs in nature, the human brain. Among neural stem cell progeny, post-mitotic neurons are likewise remarkably diverse. Single-cell transcriptomic approaches are now cataloging a long-sought-after molecular taxonomy of neuronal diversity in the brain...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2728-3
更新日期：2018-01-01 00:00:00
abstract：:The projections of ocellar fibres within the brain and thorax of the honey bee, Apis mellifera, were established using a modified cobalt sulphide technique, supplemented by serial sectioning of the brain for the light microscope. The results are: 5 large fibres in each lateral nerve and 12 in the median nerve have wid...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231405
更新日期：1977-01-24 00:00:00
abstract：:Fibres growing from neurons of explanted dorsal root ganglia from 10 day chick embryos were transected and subsequently observed by light and electron microscopy after periods of a few to fifty minutes. Changes immediately proximal and distal to the cut together with alterations further away from the site of injury on...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219562
更新日期：1978-07-10 00:00:00
abstract：:Ultrastructural and morphometric investigations were performed on the lung of the European salamander, Salamandra salamandra L. Folds of first and second order are covered with a ciliated epithelium containing goblet cells. The respiratory surface of the lung is lined by a single type of cell which, in amphibians, com...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222429
更新日期：1978-07-27 00:00:00
abstract：:Immediately following the discovery of tryptophan hydroxylase in Drosophila, we demonstrated the presence of tryptophan hydroxylase in the brain of the beetle Harmonia axyridis (Coleoptera: Coccinellidae). However, whether tryptophan hydroxylase is present in the brains of other insects is still a matter of discussion...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-008-0596-6
更新日期：2008-06-01 00:00:00
abstract：:Microfold (M) cells in the follicle-associated epithelium (FAE) of Peyer's patches contribute to the mucosal immune response by the transcytosis of microorganisms. The mechanism by which M cells take up microorganisms, and the functional proteins by which they do this, are not clear. In order to explore one such prote...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2342-1
更新日期：2016-06-01 00:00:00
abstract：:The analysis of myenteric neurons is becoming increasingly important for the assessment of enteric nervous system injury and degeneration occurring in motor disorders of the gut. Limited information is presently available on the quantitative estimation of myenteric neurons and glial cells in paraffin-embedded colonic ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0770-5
更新日期：2009-05-01 00:00:00
abstract：:The medial preoptic nucleus is a sexually dimorphic structure whose cytoarchitecture, afferent and efferent connections, and functions have been previously described. No detailed ultrastructural study has, however, been performed to date. Here we describe the ultrastructural organization of this important preoptic str...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318164
更新日期：1995-03-01 00:00:00
abstract：:To investigate the mechanisms whereby bone cells absorb organic bone-matrix components during endochondral bone development, rat humeri were examined, employing horseradish peroxidase as a soluble protein tracer. Intravenously-injected peroxidase filled the osteoid layer and penetrated into the osteocyte lacunae and c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219233
更新日期：1985-01-01 00:00:00
abstract：:The glial cell line-derived neurotrophic factor (GDNF) family ligands (GFLs) comprise a group of four homologous and potent growth factors that includes GDNF, neurturin (NRTN), artemin (ARTN), and persephin (PSPN). The survival, growth, and mitotic activities of the GFLs are conveyed by a single receptor tyrosine kina...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03235-4
更新日期：2020-10-01 00:00:00
abstract：:Correlations between the presence of surface coat and immobilization antigen of Paramecium tetraurelia were studied. Supravital, partial removal of the surface coat resulted in accelerated response of monobacterially and axenically grown cells to the homologous antiserum. Ciliates pretreated with trypsin or pronase (0...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219984
更新日期：1977-07-11 00:00:00
abstract：:Kisspeptin is a hypothalamic neuropeptide, which acts directly on gonadotropin-releasing hormone (GnRH)-secreting neurons via its cognate receptor (GPR54 or Kiss-R) to stimulate GnRH secretion in mammals. In non-mammalian vertebrates, there are multiple kisspeptins (Kiss1 and Kiss2) and Kiss-R types. Recent gene knock...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03089-5
更新日期：2020-02-01 00:00:00
abstract：:The expression of nicotinic acetylcholine receptors (nAChR) in fetal lung suggests maternal smoking during pregnancy effects newborn lung structure and function by the direct interaction of nicotine with nAChR in the developing lung. The recent identification of the lynx1 nAChR modulator protein in nicotinic neurons i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1077-9
更新日期：2005-05-01 00:00:00
abstract：:The fine structure of the pore cells in pre- and post-hatched Deroceras reticulatum is described. The cells have been divided into three main types on morphological grounds, one type being particulary rich in glycogen. Certain pore cells contain haemocyanin granules in grooves below cytoplasmic tongues, and in charact...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234637
更新日期：1979-12-01 00:00:00
abstract：:Recent evidence indicates that many molecules involved in generating and patterning the limbs also play a role during craniofacial morphogenesis. On the surface, this is an unexpected finding given that these regions of the body have separate evolutionary origins, are composed of different embryonic tissues, and are q...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s004410051271
更新日期：1999-04-01 00:00:00
abstract：:Bone morphogenetic proteins (BMPs) induce cartilage and bone formation at both bony and non-bony sites. We examined the possibility whether BMP-2 induces differentiation of osteoblast progenitors into chondroblast lineage cells using organ culture and cell culture prepared from the calvaria of newborn mouse. BMP-2 sti...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050562
更新日期：1996-04-01 00:00:00
abstract：:This work describes the origin and development of about 200 tension receptor cells located around the anterior attachment site of the locust ovipositor muscle and their migration to their final position on the muscle fibres. The locust ovipositor muscle is the only insect system in which more than 100 tension receptor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0498-z
更新日期：2007-12-01 00:00:00
