Microtubular number in the tractus hypophyseus of newborn normal rats and newborn rats with congenital diabetes insipidus.

Abstract:

:Evidence has already been adduced suggesting that an increase in microtubular number occurs in the tractus hypophyseus of rats stressed by the administration of hypertonic saline, and of rats with congenital diabetes insipidus (CDI). Since the tractus hypophyseus in these animals shows high secretory activity, it seems likely that the microtubular increase reflects the participation of microtubules in axoplasmic transport. To exclude, however, a congenital microtubular abnormality in CDI, affected newborn rats were examined. In these, the microtubular number was normal, thus suggesting that the increase in microtubular number seen in adult animals was not a congenital morphological abnormality. However, by 4 days of age there was a slight but statistically significant increase in microtubular number in affected rats, a change probably attributable to increased secretory activity.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Grainger F,Sloper JC

doi

10.1007/BF00219611

subject

Has Abstract

pub_date

1976-06-28 00:00:00

pages

405-14

issue

3

eissn

0302-766X

issn

1432-0878

journal_volume

169

pub_type

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