Abstract:
:Evidence has already been adduced suggesting that an increase in microtubular number occurs in the tractus hypophyseus of rats stressed by the administration of hypertonic saline, and of rats with congenital diabetes insipidus (CDI). Since the tractus hypophyseus in these animals shows high secretory activity, it seems likely that the microtubular increase reflects the participation of microtubules in axoplasmic transport. To exclude, however, a congenital microtubular abnormality in CDI, affected newborn rats were examined. In these, the microtubular number was normal, thus suggesting that the increase in microtubular number seen in adult animals was not a congenital morphological abnormality. However, by 4 days of age there was a slight but statistically significant increase in microtubular number in affected rats, a change probably attributable to increased secretory activity.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Grainger F,Sloper JCdoi
10.1007/BF00219611subject
Has Abstractpub_date
1976-06-28 00:00:00pages
405-14issue
3eissn
0302-766Xissn
1432-0878journal_volume
169pub_type
杂志文章abstract::Vasodilator-stimulated phosphoprotein (VASP) and mammalian-enabled protein (MENA) share similar cellular localisation and functions (signal transduction pathways, regulation of actin cytoskeleton dynamics). Functional substitution and compensation among Ena/VASP proteins have been proposed as the reason for the absenc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0964-9
更新日期:2004-12-01 00:00:00
abstract::Macrophages are present throughout the anterior pituitary gland. However, the features and function of macrophages in the gland are poorly understood. Recent studies have indicated that there are two main macrophage classes: M1 (classically activated) and M2 (alternatively activated). In this study, we examine whether...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2564-x
更新日期:2017-05-01 00:00:00
abstract::The processes involved in the regulation of bone cell metabolism are complex, including those implicated in bone cell coupling. This study was undertaken to develop a model that would permit real-time interaction between osteoclastic cells and osteoblasts in vitro. Osteogenic bone marrow stromal cells were isolated fr...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051160
更新日期:1998-10-01 00:00:00
abstract::N-CAM180, the molecular form of the three neural cell adhesion molecules (N-CAM) with the largest cytoplasmic domain, is accumulated at sites of cell-cell contact (cell bodies, neurites, growth cones) in cultures of neuroblastoma and cerebellum. At these sites the cytoskeleton-membrane linker protein brain spectrin an...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214676
更新日期:1987-10-01 00:00:00
abstract::In the ovoviviparous fly, Sarcophaga bullata, vitellogenesis in cyclic; a process reflected in ultrastructural changes in the fat body cells and oenocytes. At eclosion the larval fat body has not yet completely disappeared. During vitellogenesis the fat body cells are specialized for intensive protein synthesis showin...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216728
更新日期:1981-01-01 00:00:00
abstract::Homeobox genes encode transcription factors that regulate embryonic development programs including organogenesis, axis formation and limb development. Previously, we identified and cloned a mouse double homeobox gene, Duxbl, whose homeodomain exhibits the highest identity (67 %) to human DUX4, a candidate gene of faci...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1974-x
更新日期:2014-11-01 00:00:00
abstract::Research in mammals has demonstrated a variety of regulatory effects of vasopressin and oxytocin on endocrine functions of the anterior pituitary gland. Less evidence is available regarding the hypophysiotropic action of arginine vasotocin (AVT) comprising vasopressic and oxytocic activities in birds. Some hypophysiot...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0636-2
更新日期:2008-08-01 00:00:00
abstract::Osteoarthritis (OA) is the most common joint disease with an unsatisfactory therapy outcome and characterized by the degradation of articular cartilage and synovial inflammation. Here, we isolated bone marrow mesenchymal stem cells (BMSCs) from rat's bone marrow and BMSC-derived exosome (BMSCs-Exo) from BMSCs successf...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03319-1
更新日期:2021-01-06 00:00:00
abstract::Studies with environmental levels of various metals typically focus on observable neurological symptoms in newborns and adults. Use of the C2C12 skeletal muscle cell line as a developmental model enabled us to test whether environmental insults prevented myotube formation or the assembly of the postsynaptic component ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0878-6
更新日期:2004-05-01 00:00:00
abstract::Double-labeling immunofluorescent histochemistry demonstrates that calretinin, a calcium-binding protein, coexists with calcitonin gene-related peptide, vasoactive intestinal peptide, and substance P in the fibers innervating the lamina propria of the rat intestinal villi. An acetylcholinesterase histochemical stain r...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318366
更新日期:1995-06-01 00:00:00
abstract::Large conductance calcium-activated potassium channels (BK(ca)) are crucial for the regulation of cerebral vascular basal tone and might be involved in cerebral vasodilation relevant to migraine and stroke. We studied the differential gene expression of mRNA transcript levels and protein expression of the BK(Ca) chann...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0701-x
更新日期:2008-12-01 00:00:00
abstract::Four months after the selective ablation of inner hair cells by carboplatin, the interdental cell epithelium exhibited dilated intercellular spaces and cytosolic vacuoles not seen in controls. In addition, the wide, often electron-lucent phalanges observed in the interdental cells of the normal chinchilla collapsed in...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000253
更新日期:2000-10-01 00:00:00
abstract::Changes in the ultrastructure of the toad epidermis during the moulting cycle are described on the basis of 17 skin preparations fixed in consecutive phases of the cycle. Our previous light microscopical findings that morphological changes are mainly restricted to a short period prior to and after shedding are confirm...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221703
更新日期:1975-06-24 00:00:00
abstract::The midgut cells of Tomocerus minor (Insecta, Collembola) were examined with the electron microscope and cytochemically. The midgut epithelium consists of a series of cells characterised by numerous mineral concretions scattered throughout the cytoplasm. Mitochondria are abundant; microvilli are well developed at the ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236347
更新日期:1979-01-30 00:00:00
abstract::Two dozen hybrid clones were produced by fusion of diploid embryonic stem (ES) cells positive for green fluorescent protein (GFP) with tetraploid fibroblasts derived from DD/c and C57BL-I(I)1RK mice. Cytogenetic analysis demonstrated that most cells from these hybrid clones contained near-hexaploid chromosome sets. Ad...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-0987-3
更新日期:2010-06-01 00:00:00
abstract::Male germ cells of the greater bandicoot rat, Bandicota indica, have recently been categorized into 12 spermiogenic steps based upon the morphological appearance of the acrosome and nucleus and the cell shape. In the present study, we have found that, in the Golgi and cap phases, round spermatid nuclei contain 10-nm t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0668-7
更新日期:2008-10-01 00:00:00
abstract::Autophagy (cellular self-consumption) is an adaptive stress response and an important aspect of adaption to mechanical loading. If mechanical forces are associated with autophagy regulation in periodontal ligament (PDL) fibroblasts is still unknown. The aim of this study was to analyze the influence of force magnitude...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-03063-1
更新日期:2019-12-01 00:00:00
abstract::The prothoracicotropic hormone (PTTH), which stimulates ecdysteroid synthesis in the prothoracic glands, is produced, in the dorso-lateral protocerebrum of Manduca sexta, by paired peptidergic neurons, the lateral neurosecretory cell group III (L-NSC III). Our study revealed ultrastructural features of L-NSC III, iden...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00303082
更新日期:1994-07-01 00:00:00
abstract::We have tested the suggestion that the reported increase, in hypoxic rats, in the number of lung endocrine cells immunoreactive for the regulatory peptide CGRP is caused by an accumulation of peptide within the cells which renders them more detectable, rather than by a real increase in proliferation. The incorporation...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00338049
更新日期:1992-04-01 00:00:00
abstract::Membrane-coating granules of the epithelium of the hamster cheek pouch displayed a lamellated internal structure consisting of alternating thick and thin electron dense bands separated by translucent bands of equal width. The repeat distance of the contents was 8.5 nm +/- sd. 0.7 nm and the thickness of the major elec...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00224374
更新日期:1978-02-24 00:00:00
abstract::The localization of autologous antiperoxidase immunoglobulin G (IgG) was studied in the choroid plexus of Lewis rats immunized against horseradish peroxidase (HRP). This experiment was performed to study the permeability of the choroid plexus to intravascular IgG. It was shown that autologous IgG was present in the ex...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215159
更新日期:1984-01-01 00:00:00
abstract::Expression of heat-shock protein 47 in intact and fibrotic liver and in hepatic constituent cells was investigated in mice. Immunohistochemical study of intact liver and Western blot analysis of the protein from isolated liver cells revealed that stellate cells and smooth muscle cells of interlobular vessels, but not ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050594
更新日期:1996-05-01 00:00:00
abstract::Fibrosis is the result of a wound-healing response that fails to restore normal tissue structure function. One of the critical hallmarks of fibrosis is disrupted collagen remodeling. In tissue homeostasis, the production, deposition and organization of collagen is balanced by the degradation and remodeling of collagen...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-016-2440-8
更新日期:2016-09-01 00:00:00
abstract::Neurosecretory pathways were examined in normal male rats by the use of the immunoperoxidase technique for the localization of neurophysin in Bouin-fixed, deparaffinized sections. Using this technique two projections of extrahypothalamic neuorosecretory fibers can be traced to the sites of origin of the choid plexuses...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00232829
更新日期:1977-03-01 00:00:00
abstract::The effects, on the maternal mammary gland, of diets containing similar lipid percentages but differing in composition of polyunsaturated fatty acids (PUFA) have been assessed in rats during pregnancy and lactation. For this purpose, tuna fish oil (an n-3-PUFA-enriched oil) and corn oil (an n-6-PUFA-enriched oil) were...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-012-1523-4
更新日期:2013-03-01 00:00:00
abstract::A continuous cell line was previously obtained by Simian Virus (SV) 40 transformation of primary cultures of dissociated mouse fetal hypothalami. One clone from this cell line has been previously shown to possess some of the ultrastructural features, immunological properties and synthesizing capacities of magnocellula...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219699
更新日期:1976-08-16 00:00:00
abstract::To identify structures involved in the translocation of the synaptic vesicles towards the presynaptic membrane, an ultrastructural study has been undertaken by means of (1) the E-PTA stain and (2) the HMM-labeling procedure. Using serial sections of E-PTA stained nervous tissue, especially those made in transversal an...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219841
更新日期:1975-06-27 00:00:00
abstract::The median eminence/pituitary stalk represents the final common pathway for fibers from neurons that project to the pituitary gland. We have used the lipophilic fluorescent tracer 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI) to determine the location of neurons projecting to the median emin...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00304513
更新日期:1995-04-01 00:00:00
abstract::Duck muscle spindles show a large outer capsule enclosing a number of intrafusal muscle fibres which are individually encircled by an inner capsule. The outer capsule consists of a multilayer of 4-6 flattened cells with elongated nuclei, and are usually lined by a basement membrane. They resemble and are linked with p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234400
更新日期:1980-01-01 00:00:00
abstract::The fine structure and primary sensory projections of sensilla located in the labial-palp pit organ of the cotton bollworm Helicoverpa armigera (Insecta, Lepidoptera) are investigated by scanning electron and transmission electron microscopy combined with confocal laser scanning microscopy. The pit organ located on th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-013-1657-z
更新日期:2013-09-01 00:00:00