Abstract:
:The morphology of enterochromaffin (EC) cells in the human fundic mucosa was investigated at the light-microscopic level by means of the unlabeled peroxidase anti-peroxidase method, with the use of a highly specific anti-serotonin serum. EC-cells in the human fundic mucosa were sparsely distributed below the neck portion of the gland, but were found to be rather numerous in its lower half. Immunohistochemistry revealed marked pleomorphic and seemingly polynuclear EC-cells or cells with long, sometimes multipolar cytoplasmic processes. In addition, luminal contacts and contiguity between EC-cells, or interglandular connections were also encountered. The present immunohistochemical procedure permits, for the first time, a clear-cut morphological visualization of the entire population of EC-cells, and reveals the distinctive morphological features of these cells in the human fundic mucosa. These morphological findings imply that EC-cells in the fundic mucosa may be crucial in gastric function.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Inokuchi H,Kawai K,Takeuchi Y,Sano Ydoi
10.1007/BF00226973subject
Has Abstractpub_date
1984-01-01 00:00:00pages
703-5issue
3eissn
0302-766Xissn
1432-0878journal_volume
235pub_type
杂志文章abstract::The development of the heterophil granulocytes in the bone marrow of the guinea pig is described. During the maturation of these cells, three types of granule are formed, not only the azurophil and specific granules already described in other mammals but also a third type of granule referred to here as the nucleated g...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220388
更新日期:1978-11-20 00:00:00
abstract::Fragments of pituitary tissue obtained from a total of 37 patients with either breast cancer, diabetic retinopathy, galactorrhea, or acromegaly were dissociated into single cell suspensions prior to cell culture. Release of human growth hormone (hGH) and human prolactin (hPRL) into the culture medium was measured by r...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219803
更新日期:1978-08-16 00:00:00
abstract::Black tiger shrimps (Penaeus monodon) are able to survive and can be reared under various salinities, possibly by the cellular adaptation of their excretory system, particularly the antennal gland, which is known to regulate body fluid in crustaceans. We have investigated the morphological and biochemical alterations ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-0971-y
更新日期:2010-06-01 00:00:00
abstract::It is known that human and animal fibroblasts are able to induce the retraction of a fibrin clot. In the present study the correlation between (i) fibrin-fibroblasts during growth, (ii) the number of actin stress-lines in mouse fibroblasts during growth in culture, and (iii) the sensitivity of actin stress-lines to a ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218485
更新日期:1982-01-01 00:00:00
abstract::Chronic tissue injury with fibrosis results in the disruption of tissue architecture, organ dysfunction and eventual organ failure. Therefore, the development of effective anti-fibrotic therapies is urgently required. During fibrogenesis, complex interplay occurs between cellular and extracellular matrix components of...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-016-2407-9
更新日期:2016-09-01 00:00:00
abstract::Fueled by the discovery of head regeneration in triclads (planarians) two and a half centuries ago, flatworms have been the focus of regeneration research. But not all flatworms can regenerate equally well and to obtain a better picture of the characteristics and evolution of regeneration in flatworms other than plana...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03302-w
更新日期:2020-11-07 00:00:00
abstract::Hepatic stellate cells become activated and aquire contractility on being cultured. In order to characterize the morphology of contracted and relaxed stellate cells, we performed light- and electron-microscopic analyses of cultured stellate cells on collagen gels. Incubation of stellate cells with medium alone, 10 nM ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050717
更新日期:1996-12-01 00:00:00
abstract::Pituitary somatotrops were localized in four species from the genus Oncorhynchus using an antiserum to chum salmon (Oncorhynchus keta) growth hormone. The antiserum cross-reacted specifically with the acidophils in the caudal pars distalis of all species tested. Corroborative immunodiffusion studies were also conducte...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218126
更新日期:1983-01-01 00:00:00
abstract::The chemical nature of the thickened plasma membrane of cornified cells in stratified squamous epithelium was investigated in comparison with that in noncornified epithelium. Localizations of transglutaminase, molecular weight 92,000 daltons, and detection of epidermal cysteine proteinase inhibitor were effected with ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215516
更新日期:1987-08-01 00:00:00
abstract::Angiotensin II (AII) is present in the mammalian ovary and has been correlated with atresia in follicles. Since the theca interna may be one site at which atresia is initiated, we wished to determine whether AII exerts an effect on theca interna from explanted ovarian follicles of hamsters. Hamsters were sacrified on ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00338068
更新日期:1992-04-01 00:00:00
abstract::SCO-spondin is a newly identified protein, strongly expressed in the subcommissural organ (SCO), an ependymal differentiation of the brain. When secreted into the cerebrospinal fluid at the entrance to the Sylvian aqueduct, it condenses and forms Reissner's fiber. Several conserved domains have previously been charact...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051132
更新日期:1998-09-01 00:00:00
abstract::It is possible to determine statistically the repartitions of shapes or sizes in a population of particles from the recurrence of shapes or sizes of their outlines in microscopical sections. This method was applied to a population of 1326 follicular profiles randomly sampled from 30 ovaries of pubescent homozygous "Nu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219416
更新日期:1976-07-30 00:00:00
abstract::Hypothalamic slices containing the lateral hypothalamic area (LHA) were prepared from 6- to 8-day-old rats and maintained in stationary culture for up to 35 days in order to analyse how well the melanin-concentrating hormone (MCH) neurons survived. As previously reported for other brain areas, this method yielded a lo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051330
更新日期:1999-07-01 00:00:00
abstract::The ultrastructure of immunoreactive somatotrophs and lactotrophs in pituitaries of fetal rats at 19, 20 and 21 days of gestation and on the day of birth was studied. Somatotrophs, first detectable at 19 days of gestation, undergo only minor modifications before reaching the structure described for adults. In particul...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213955
更新日期:1986-01-01 00:00:00
abstract::Noses are extremely sophisticated chemical detectors allowing animals to use scents to interpret and navigate their environments. Odor detection starts with the activation of odorant receptors (ORs), expressed in mature olfactory sensory neurons (OSNs) populating the olfactory mucosa. Different odorants, or different ...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-020-03327-1
更新日期:2021-01-06 00:00:00
abstract::In the present study, we have analyzed the direct effects of cytokines, which mediate the acute-phase response in liver, on connexin expression and gap-junctional intercellular communication in immortalized MHSV12 mouse hepatocytes. When these cells were stimulated for 24 h with interleukin 1 and interleukin 6, the am...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051184
更新日期:1998-11-01 00:00:00
abstract::Apart from the characteristic and progressive motor- and movement-related problems, Parkinson's disease (PD) patients also suffer from several non-motor symptoms, including gastrointestinal dysfunction. The fact that the enteric nervous system (ENS) controls motility and that one of the typical PD hallmarks, α-synucle...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-018-2856-4
更新日期:2018-07-01 00:00:00
abstract::The colocalization of immunoreactivities to substance P and calcitonin gene-related peptide (CGRP) in nervous structures and their correlation with other peptidergic structures were studied in the stellate ganglion of the guinea pig by the application of double-labelling immunofluorescence. Three types of fibre were d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318563
更新日期:1993-06-01 00:00:00
abstract::Intra-arterial injections of synthetic double-stranded RNA (polyinosinic:polycytidylic acid, PIPC) at a dose of 500 microg/kg evoked pronounced fever in guinea-pigs. PIPC-induced fever could be antagonized by treatment with the non-selective cyclooxygenase (COX) inhibitor diclofenac and was, in part, attenuated by the...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0386-6
更新日期:2007-06-01 00:00:00
abstract::Activities of the H+, K(+)-ATPase and the Na+, K+, ATPase have been localized in the morphologically heterogeneous oxyntic cell lineage of adult bovine abomasal mucosa, by means of K(+)-dependent paranitrophenylphosphatase (K(+)-pNPPase) histochemistry. At the light- and electron-microscopic level, only members of the...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050583
更新日期:1996-05-01 00:00:00
abstract::Regions within frog semitendinosus muscle that are rich in tonic muscle cells were identified histochemically by myosin adenosine triphosphatase- and succinic dehydrogenase-staining procedures. Bundles of cells still attached to tendinous insertions were removed from those sites, prepared for electron microscopy and s...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213937
更新日期:1986-01-01 00:00:00
abstract::The cerebral ganglia of the freshwater snail Lymnaea stagnalis contain two clusters of neurosecretory Caudo-Dorsal Cells (CDC). These cells produce a neurohormone which stimulates ovulation. Ganglion transplantation and quantitative electron microscopy show that neuronal isolation of the cerebral ganglia complex (CCC)...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219720
更新日期:1976-04-28 00:00:00
abstract::The opioid peptide dynorphin A (1-17) is the third transmitter identified in the striatonigral projection, the other two being gamma-aminobutyric acid (GABA) and substance P. The ultrastructural features of the dynorphinergic terminals in substantia nigra/pars reticulata were studied using pre-embedding immunocytochem...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00329443
更新日期:1990-07-01 00:00:00
abstract::The ultrastructure of the contractile apparatus of the rat soleus muscle during the course of denervation atrophy was investigated. It was found that the ratio of thin the thick filaments increased in myofibrils of atrophying muscle fibers. Elevation of the ratio was observed as early as the second day after denervati...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216767
更新日期:1981-01-01 00:00:00
abstract::Four forms of short neuropeptide F (sNPF1-4), derived from the gene snpf, have been identified in Drosophila and are known to act on a single G-protein-coupled receptor (sNPFR). Several functions have been suggested for sNPFs in Drosophila, including the regulation of feeding and growth in larvae, the control of insul...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-013-1660-4
更新日期:2013-09-01 00:00:00
abstract::The effect of hypothyroidism, induced by 4-propyl-2-thiouracil, on muscle satellite cells in vivo and in vitro, and on postnatal muscle fiber development in the soleus muscle of rats during the first 40 days of postnatal life was analyzed. The proliferative activity of satellite cells was determined by means of bromod...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050682
更新日期:1996-10-01 00:00:00
abstract::The localization of (Na+-K+) ATPase in the intact electrocyte of the electric organ of Electrophorus electricus (L.) and its subcellular fractions was investigated by biochemical and cytochemical methods. The distribution of AChE activity in the subcellular fractions was also comparatively analysed with this enzyme se...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226673
更新日期:1977-11-30 00:00:00
abstract::Glycoproteins rich in mannosyl or glucosyl residues were analyzed in the subcommissural organ (SCO) and the pineal organ of the sheep (Ovis aries). By use of concanavalin A labelled with fluorescein isothiocyanate, fluorescent material was found both in ependymal and hypendymal cells of the SCO. In the pineal organ, e...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218562
更新日期:1986-01-01 00:00:00
abstract::In the pond snail Lymnaea stagnalis, the growth regulating system consists of (1) about 200 neuroendocrine light green cells, located in four clusters in the cerebral ganglia, and (2) the paired canopy cells, located in the lateral lobes. These cells express genes encoding the molluscan insulin-related peptides (MIPs)...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00384739
更新日期:1992-07-01 00:00:00
abstract::Epidermal septate junctions of Nereis sp. and Cirriformia sp. fixed with OsO4 or glutaraldehyde/OsO4 display variable structure in electron micrographs. In transverse section the septa are often indistinct and obscured by opaque material that fills the junctional cleft. Septa (spaced at 180--280 A) are more clearly de...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222150
更新日期:1976-10-22 00:00:00