Abstract:
:Infection by influenza virus leads to respiratory failure characterized by acute lung injury associated with alveolar edema, necrotizing bronchiolitis, and excessive bleeding. Severe reactions to infection that lead to hospitalizations and/or death are frequently attributed to an exuberant host response, with excessive inflammation and damage to the epithelial cells that mediate respiratory gas exchange. The respiratory mucosa serves as a physical and chemical barrier to infection, producing mucus and surfactants, anti-viral mediators, and inflammatory cytokines. The airway epithelial cell layer also serves as the first and overwhelmingly primary target for virus infection and growth. This review details immune events during influenza infection from the viewpoint of the epithelial cells, secretory host defense mechanisms, cell death, and recovery.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Sanders CJ,Doherty PC,Thomas PGdoi
10.1007/s00441-010-1043-zsubject
Has Abstractpub_date
2011-01-01 00:00:00pages
13-21issue
1eissn
0302-766Xissn
1432-0878journal_volume
343pub_type
杂志文章,评审abstract::In the rostral hypothalamus of the domestic fowl, the magnocellular neurosecretory nuclei show a peculiar differentiation. Golgi studies of the supraoptic and paraventricular nuclei of the fowl reveal at least two major cell types: 1) large multipolar neurons, and 2) small interneurons. Golgi impregnations provide a d...
journal_title:Cell and tissue research
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abstract::Pituitary adenylate cyclase-activating polypeptide (PACAP) is the latest member of the vasoactive intestinal polypeptide (VIP) family of neuropeptides present in nerve fibres in many peripheral organs. Using double immunohistochemistry, with VIP as a marker for intrinsic innervation and calcitonin-gene related peptide...
journal_title:Cell and tissue research
pub_type: 杂志文章
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abstract::Sigma receptor 1 (σR1), a non-opiate transmembrane protein located on endoplasmic reticulum (ER) and mitochondrial membranes, is considered to be a molecular chaperone. Marked protection against cell death has been observed when ligands for σR1 have been used in in vitro and in vivo models of retinal cell death. Mice ...
journal_title:Cell and tissue research
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abstract::This study provides information on the rates of DNA synthesis, sites of DNA synthesis, and DNA content of the avian salt gland during the osmotic stressing (plasma membrane synthesis) and destressing (plasma membrane turnover) cycle, in an effort to better understand the relationship of cell turnover to the initial ev...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214782
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abstract::Dental pulp stem cells (DPSCs) are a type of mesenchymal stem cell (MSC) characterized by multi-lineage differentiation making it an attractive choice for tissue regeneration. However, before DPSCs can be used for cell-based therapy, we have to understand their biological properties in response to intrinsic and extrin...
journal_title:Cell and tissue research
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abstract::The effect of vascular endothelial growth factor (VEGF165) on the chorioallantoic membrane (CAM) of 13-day-old chick embryos was studied. The factor was applied in doses of 0.5-4 micrograms for a period of up to 4 days. Macroscopical, histological and immunohistological studies were carried out. The localization of th...
journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00235152
更新日期:1981-01-01 00:00:00
abstract::The presence and distribution in the peri-insular region of extracellular matrix, and in particular basement membrane, was investigated in a comparative study comprising pancreata of rat, dog, pig, and man. Basement membrane markers, collagen type-IV and laminin, were determined immunohistochemically. Additional infor...
journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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更新日期:2021-01-29 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215882
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-017-2726-5
更新日期:2018-02-01 00:00:00
abstract::Developmental alterations of paranodal fiber segments have not been investigated systematically in human nerve fibers at the light- and electron-microscopic level. We have therefore analyzed developmental changes in the fine structure of the paranode in 43 human sural nerves during the axonal growth period up to 5 yea...
journal_title:Cell and tissue research
pub_type: 杂志文章
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更新日期:1993-09-01 00:00:00
abstract::The fine structure of the horny teeth of the lamprey, Entosphenus japonicus, was examined by light- and electron-microscopy. Most of the horny teeth consisted of two horny and two nonhorny layers. The primary horny layer was well keratinized, and the cells were closely packed and intensely interdigitated, being joined...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215769
更新日期:1983-01-01 00:00:00
abstract::Autoradiograms of mouse pituitaries were prepared 30 min after injection of 3H-dexamethasone (3HDM), 3H-corticosterone (3HB) and 3H-cortexolone (3HS) either alone or in the presence of competing unlabelled steroids. 3H-dexamethasone accumulated in cell nuclei of both the pars distalis and the pars nervosa but not in t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236423
更新日期:1979-08-01 00:00:00
abstract::There is general consensus that enteroendocrine cells, EEC, containing the enteric hormone cholecystokinin (CCK) are confined to the small intestine and predominate in the duodenum and jejunum. Contrary to this, EEC that express the gene for CCK have been isolated from the large intestine of the mouse and there is evi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-017-2612-1
更新日期:2017-08-01 00:00:00
abstract::The spatial and temporal distribution of three peptides, DSK I, DSK II, and DSK 0, encoded by the Drosophila melanogaster drosulfakinin (Dsk) gene, have been examined in the central nervous system. DSK I and DSK II have a -RFamide C-terminus and are structurally similar to sulfakinin peptides; in contrast, DSK 0 conta...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050518
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00239217
更新日期:1979-10-02 00:00:00
abstract::Neuroblastoma is an embryonal malignancy that affects normal development of the adrenal medulla and paravertebral sympathetic ganglia in early childhood. Extensive studies have revealed the molecular characteristics of human neuroblastomas, including abnormalities at genome, epigenome and transcriptome levels. However...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-017-2692-y
更新日期:2017-12-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
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doi:10.1007/s00441-001-0503-x
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abstract::The fan-shaped body is the largest substructure of the central complex in Drosophila melanogaster. Two groups of large-field neurons that innervate the fan-shaped body, viz., F1 and F5 neurons, have recently been found to be involved in visual pattern memory for "contour orientation" and "elevation" in a rut-dependent...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-009-0781-2
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abstract::The morphology and histology of the tibial auditory system of the New Zealand weta, Hemideina crassidens, are described. The groups of acoustic sensilla conform closely to the subgenual organ, intermediate organ and crista acoustica of the Tettigoniidae. Each prothoracic tibia bears two thick (40-100 micrometers) tymp...
journal_title:Cell and tissue research
pub_type: 杂志文章
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abstract::The effect of pilocarpine and food uptake on the rate of incorporation of [3H]-leucine in vivo was measured by means of quantitative radioautography in three exocrine cells of the rat: the acinar and the granular duct cells of the submandibular and the acinar cells of the parotid gland. The three cell types react diff...
journal_title:Cell and tissue research
pub_type: 杂志文章
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216742
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journal_title:Cell and tissue research
pub_type: 杂志文章
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更新日期:1991-11-01 00:00:00