Abstract:
:The effect of pilocarpine and food uptake on the rate of incorporation of [3H]-leucine in vivo was measured by means of quantitative radioautography in three exocrine cells of the rat: the acinar and the granular duct cells of the submandibular and the acinar cells of the parotid gland. The three cell types react differently. The submandibular acinar cells showed a decrease in incorporation rate after pilocarpine administration but not after feeding. The incorporation rate of the granular duct cells of the submandibular gland remains constant after both stimulations. The acinar cells of the parotid gland show an increase in incorporation rate of [3H]-leucine in response to both. The contrast between the submandibular and the parotid gland could also be demonstrated radiobiochemically, the results reflecting the incorporation rates of the acinar cells of both glands, giving no information on the contribution of other cell types. The decrease in incorporation rate of the submandibular gland acinar cells is accompained by a shift of polyribosomes towards monomers.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Kuijper-Lenstra AH,Kramer MF,van Venrooij WJdoi
10.1007/BF00219936keywords:
subject
Has Abstractpub_date
1975-12-18 00:00:00pages
447-56issue
4eissn
0302-766Xissn
1432-0878journal_volume
164pub_type
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