Rate of protein synthesis in rat salivary gland cells after pilocarpine or feeding. II. Protein synthesis in vivo in cells of the submandibular and parotid gland after secretion.


:The effect of pilocarpine and food uptake on the rate of incorporation of [3H]-leucine in vivo was measured by means of quantitative radioautography in three exocrine cells of the rat: the acinar and the granular duct cells of the submandibular and the acinar cells of the parotid gland. The three cell types react differently. The submandibular acinar cells showed a decrease in incorporation rate after pilocarpine administration but not after feeding. The incorporation rate of the granular duct cells of the submandibular gland remains constant after both stimulations. The acinar cells of the parotid gland show an increase in incorporation rate of [3H]-leucine in response to both. The contrast between the submandibular and the parotid gland could also be demonstrated radiobiochemically, the results reflecting the incorporation rates of the acinar cells of both glands, giving no information on the contribution of other cell types. The decrease in incorporation rate of the submandibular gland acinar cells is accompained by a shift of polyribosomes towards monomers.


Cell Tissue Res


Cell and tissue research


Kuijper-Lenstra AH,Kramer MF,van Venrooij WJ





Has Abstract


1975-12-18 00:00:00












  • Potent inhibition of interleukin-6 expression in a human astrocytoma cell line by tenidap.

    abstract::Tenidap is a structurally novel antirheumatic agent with anti-inflammatory and analgesic properties. Previous studies have shown that tenidap is able to inhibit the production and action of cytokines such as interleukin-1, interleukin-6 (IL-6) and tumour necrosis factor alpha. However, the mechanisms by which tenidap ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Lieb K,Fiebich BL,Hüll M,Berger M,Bauer J

    更新日期:1997-05-01 00:00:00

  • Distribution of P75 neurotrophin receptor in adult human cochlea--an immunohistochemical study.

    abstract::Mechanisms underlying the unique survival property of human spiral neurons are yet to be explored. P75 (p75(NTR)) is a low affinity receptor for neurotrophins and is known to interact with Trk receptors to modulate ligand binding and signaling. Up-regulation of this receptor was found to be associated with apoptosis a...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Liu W,Glueckert R,Kinnefors A,Schrott-Fischer A,Bitsche M,Rask-Andersen H

    更新日期:2012-06-01 00:00:00

  • Ultracytochemical evidence for a proton-pump adenosine triphosphatase in chick osteoclasts.

    abstract::The distribution of Mg++-ATPase in osteoclasts along the endosteal surface of the chick tibia was investigated by neutral and alkaline pH cytochemical methods at the electron-microscopic level. Reaction product was observed in mitochondria, cytoplasmic vesicles, and ruffled-border membrane. Levamisole, ouabain, and va...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Akisaka T,Gay CV

    更新日期:1986-01-01 00:00:00

  • Two types of mammosomatotropes in mouse adenohypophysis.

    abstract::Two types of mammosomatotropes (MS), the small-granule and vesicle-granule MS, were detected in mouse adenohypophysis by electron microscopy and immunohistochemistry. Both cell-types were immunoreactive to prolactin (PRL) and growth hormone (GH) antisera. The small-granule MS contained small, round, solid secretory gr...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Sasaki F,Iwama Y

    更新日期:1989-06-01 00:00:00

  • The adenohypophysis of the flounder, Pleuronectes flesus, and the minnow, Phoxinus phoxinus.

    abstract::The pituitary gland of the flounder, Pleuronectes flesus, showed several unusual cytological features. Between the RPD and the PPD was a zone of cells that stained purple with Alcian blue--PAS--orange G. Many of these cells were apparently degenerating. In the PPD the strands and coils of presumptive STH cells showed ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Benjamin M

    更新日期:1975-01-01 00:00:00

  • Tritiated thymidine autoradiographic study on cellular migration in the gastric gland of the golden hamster.

    abstract::Ten hamsters received repeated injections of 3H-thymidine for 4 days and were allowed to survive for 7, 28, 42 and 100 days. Changes in spatial distribution of the labelled cells and in labelling indices of each cell line in the gastric glands were studied at various days after 3H-thymidine, the labelled parietal cell...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Hattori T,Fujita S

    更新日期:1976-09-14 00:00:00

  • Immunocytochemical studies on the LHRH system of the Japanese quail: influence by photoperiod and aspects of sexual differentiation.

    abstract::Immunocytochemistry was used to determine if photoperiod and/or sex have any effect on the pattern of the luteinizing hormone-releasing hormone (LHRH) system in the brain of the Japanese quail. Immunopositive perikarya were found within three major areas of the brain: the rostral paraolfactory lobe, the preoptic, and ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Foster RG,Panzica GC,Parry DM,Viglietti-Panzica C

    更新日期:1988-08-01 00:00:00

  • Appearance of tyrosine hydroxylase, aromatic amino-acid decarboxylase, dopamine beta-hydroxylase and phenylethanolamine N-methyltransferase during the ontogenesis of the adrenal medulla: an immunohistochemical study in the rat.

    abstract::The cellular localization of the enzymes tyrosine hydroxylase (TH), aromatic amino-acid decarboxylase (or dopa decarboxylase, DDC), dopamine beta-hydroxylase (DBH) and phenylethanolamine N-methyltransferase (PNMT) in the adrenal medulla of adult rats and rat fetuses (14th, 17th, 18th, 19th and 21st day) was examined. ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Verhofstad AA,Hökfelt T,Goldstein M,Steinbusch HW,Joosten HW

    更新日期:1979-08-03 00:00:00

  • Primary culture of capillary endothelial cells from the spiral ligament and stria vascularis of bovine inner ear. Retention of several endothelial cell properties in vitro.

    abstract::Methods for isolation and culture of microvascular endothelial cells of the inner ear were devised to provide an in-vitro system for studying endothelial functions in this tissue. Capillaries from the stria vascularis and spiral ligament were treated enzymatically to free them from surrounding tissue. Contamination by...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Bowman PD,Rarey K,Rogers C,Goldstein GW

    更新日期:1985-01-01 00:00:00

  • Preservation of caprine preantral follicle viability after cryopreservation in sucrose and ethylene glycol.

    abstract::Caprine preantral follicles within ovarian fragments were cryopreserved in the absence or presence of 0.5 M sucrose with or without 1 M dimethyl sulfoxide and/or 1 M ethylene glycol (EG). After being thawed, they were washed in minimum essential medium with or without 0.3 M sucrose. Histological analysis of follicle i...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Santos RR,Tharasanit T,Figueiredo JR,van Haeften T,van den Hurk R

    更新日期:2006-09-01 00:00:00

  • Ultra-structural identification of interstitial cells of Cajal in the zebrafish Danio rerio.

    abstract::The interstitial cells of Cajal (ICCs) are important mediators of gastrointestinal (GI) motility because of their role as pacemakers in the GI tract. In addition to their function, ICCs are also structurally distinct cells most easily identified by their ultra-structural features and expression of the tyrosine kinase ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Ball ER,Matsuda MM,Dye L,Hoffmann V,Zerfas PM,Szarek E,Rich A,Chitnis AB,Stratakis CA

    更新日期:2012-08-01 00:00:00

  • Ontogeny of the GnRH systems in zebrafish brain: in situ hybridization and promoter-reporter expression analyses in intact animals.

    abstract::The ontogeny of two gonadotropin-releasing-hormone (GnRH) systems, salmon GnRH (sGnRH) and chicken GnRH-II (cGnRH-II), was investigated in zebrafish (Danio rerio). In situ hybridization (ISH) first detected sGnRH mRNA-expressing cells at 1 day post-fertilization (pf) anterior to the developing olfactory organs. Subseq...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Palevitch O,Kight K,Abraham E,Wray S,Zohar Y,Gothilf Y

    更新日期:2007-02-01 00:00:00

  • The fine structure and innervation of gill lamellae in Anodonta.

    abstract::Gill lamellae of a bivalve Anodonta woodiana lauta (v. Martens) were observed by electron microscopy. The Anodonta gill wall consists of a single layer of epithelial cells, its basal lamina and the underlying connective tissue layer. It was confirmed that there is no true endothelium in the vessels and that the connec...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Nakao T

    更新日期:1975-01-01 00:00:00

  • Regeneration of the flatworm Prosthiostomum siphunculus (Polycladida, Platyhelminthes).

    abstract::Fueled by the discovery of head regeneration in triclads (planarians) two and a half centuries ago, flatworms have been the focus of regeneration research. But not all flatworms can regenerate equally well and to obtain a better picture of the characteristics and evolution of regeneration in flatworms other than plana...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Schadt T,Prantl V,Grosbusch AL,Bertemes P,Egger B

    更新日期:2020-11-07 00:00:00

  • Cytomorphological study on human submandibular gland following treatment with secretagogue drugs.

    abstract::Using specimens of human submandibular glands, we have investigated in vitro the morphological modifications induced by clozapine, a dibenzodiazepine derivative that is used in psychotic patients and that provokes hypersalivation, a side-effect of therapy. The effects of the drug, used alone or in combination with car...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Testa Riva F,Puxeddu R,Loy F,Conti G,Riva A

    更新日期:2006-05-01 00:00:00

  • Cerebrospinal fluid-contacting neurons in the paraventricular organ and in the spinal cord of the quail embryo: a fluorescence-histochemical study.

    abstract::Although the cerebrospinal fluid-contacting neurons of the avian paraventricular organ exhibit considerable amounts of catecholamines, they show no tyrosine hydroxylase immunoreactivity. In the quail embryo, the development of these neurons has been studied using the paraformaldeyde-glutaraldeyde method for the fluore...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Guglielmone R

    更新日期:1995-07-01 00:00:00

  • The fine structure of the centrohelidian heliozoan Heterophrys marina.

    abstract::The fine structure of Heterophrys marina (Centrohelidia, Heliozoa) is described with special reference to centroplast structure, morphogenesis and "behavior" of kinetocysts (= axopodial granules which perform saltatory movement), and formation of organic spicules in a new type of organelle located in the plasma membra...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Bardele CF

    更新日期:1975-08-01 00:00:00

  • Plasticity and regulatory mechanisms of Hox gene expression in mouse neural crest cells.

    abstract::In amniotes, the developmental potentials of neural crest cells differ between the cranium and the trunk. These differences may be attributable to the different expression patterns of Hox genes between cranial and trunk neural crest cells. However, little is known about the factors that control Hox genes expression in...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Ishikawa S,Ito K

    更新日期:2009-09-01 00:00:00

  • Role of endocardial endothelial cells in the turnover of hyaluronan in Atlantic cod (Gadus morhua).

    abstract::The fate of the major connective tissue polysaccharide hyaluronan, as it appears after release from the matrix, was studied in the Atlantic cod by use of subcutaneous administration of hyaluronan conjugated with fluorescein isothiocyanate (FITC) and labelled with 125I. After administration, the ligand was transported ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Sorensen KK,Dahl LB,Smedsrod B

    更新日期:1997-10-01 00:00:00

  • From head to toe: conservation of molecular signals regulating limb and craniofacial morphogenesis.

    abstract::Recent evidence indicates that many molecules involved in generating and patterning the limbs also play a role during craniofacial morphogenesis. On the surface, this is an unexpected finding given that these regions of the body have separate evolutionary origins, are composed of different embryonic tissues, and are q...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Schneider RA,Hu D,Helms JA

    更新日期:1999-04-01 00:00:00

  • Morphological and functional changes in the tight junctions of the bile canaliculi induced by bile duct ligation.

    abstract::Thin sections after bile duct ligation showed that the depth of tight junctions appeared to increase and that the distance between individual punctate contacts appeared to become irregular and wider than in controls. The freeze fracture replicas clearly demonstrated these changes in the tight junction morphology. Chan...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Koga A,Todo S

    更新日期:1978-12-28 00:00:00

  • Identification and characterization of an antimicrobial peptide, lysozyme, from Suncus murinus.

    abstract::Lysozyme is one of the most prominent antimicrobial peptides and has been identified from many mammalian species. However, this enzyme has not been studied in the order Insectivora, which includes the most primitive placental mammals. Here, we done the lysozyme cDNA from Suncus murinus (referred to as suncus, its labo...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Takemi S,Ojima S,Tanaka T,Sakai T,Sakata I

    更新日期:2019-06-01 00:00:00

  • Scanning electron microscopic study of the freeze-fractured pineal body of the rat.

    abstract::The three-dimensional ultrastructure of the pineal body of the rat is described on the basis of freeze-fractured preparations. The pineal capsule consists of irregular cells with very flat and perforated processes. Through these openings, extremely branched canaliculi, extending to almost every pineal cell, communicat...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Krstić RV

    更新日期:1979-09-02 00:00:00

  • Morphology of horizontal cells in the frog retina.

    abstract::Two types of horizontal cells, H1 and H2, were classified using the Golgi technique on flat mounts of the retina of the frog. Cell type H1 possesses rather short, thick dendrites; the diameter of its dendritic field ranges from 40-90 micrometers. H2-cell displays long and thin dendrites; the diameter of its dendritic ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Stephan P,Weiler R

    更新日期:1981-01-01 00:00:00

  • Cellular interconnections in the young mouse ovary. Freeze-fracture study.

    abstract::Intercellular junctions in the young mouse ovary were examined by electron microscopy utilizing freeze-fracture and thin-sectioning techniques. Projections from the granulosa cells adjacent to the oocyte (GI) traverse the zona pellucida and form small gap junctions on the oocyte surface. On the P-face of these cells, ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Toshimori K,Oura C

    更新日期:1982-01-01 00:00:00

  • Gene expression and localization of diacylglycerol kinase isozymes in the rat spinal cord and dorsal root ganglia.

    abstract::The dorsal root ganglion (DRG) and dorsal horn of the spinal cord are areas through which primary afferent information passes enroute to the brain. Previous studies have reported that, during normal neuronal activity, the regional distribution of a second messenger, diacylglycerol (DG), which is derived from phosphoin...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Sasaki H,Hozumi Y,Hasegawa H,Ito T,Takagi M,Ogino T,Watanabe M,Goto K

    更新日期:2006-10-01 00:00:00

  • Distribution of neuropeptide Y-like immunoreactivity in the brain of the bichir, Polypterus senegalus, with special regard to the terminal nerve.

    abstract::The distribution of neuropeptide Y (NPY)-like immunoreactivity in the brain of the bichir, Polypterus senegalus, was examined immunohistochemically. NPY-like immunoreactivity was distributed widely in the brain, with the highest density in the diencephalon. NPY-positive perikarya were found in various areas, including...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Chiba A

    更新日期:1997-08-01 00:00:00

  • Acid phosphatase activity and intracellular collagen degradation by fibroblasts in vitro.

    abstract::Human gingival fibroblasts were cultured with collagen fibrils. The precise process of collagen phagocytosis and the relationship between acid phosphatase activity and intracellular degradation of collagen were investigated by cytochemical methods at the ultrastructural level. The collagen fibrils were first engulfed ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Yajima T

    更新日期:1986-01-01 00:00:00

  • Cyclooxygenase-1 and cyclooxygenase-2 expression in rat kidney and adrenal gland after stimulation with systemic lipopolysaccharide: in situ hybridization and immunocytochemical studies.

    abstract::Cyclooxygenase-2 (COX-2) is a recently discovered isoform of cyclooxygenase that is inducible by various types of inflammatory stimuli. Although this enzyme is considered to play a major role in inflammation processes by catalyzing the production of prostaglandins, the precise location, distribution, and regulation of...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Ichitani Y,Holmberg K,Maunsbach AB,Haeggström JZ,Samuelsson B,De Witt D,Hökfelt T

    更新日期:2001-02-01 00:00:00

  • Nerve growth factor receptor signaling in proliferation of normal adult rat chromaffin cells.

    abstract::Adult rat chromaffin cells may proliferate or extend neurites when stimulated by nerve growth factor (NGF) but their response is predominantly proliferative, making them a unique model for studying how mitogenic specificity is achieved. We examined contributions of the NGF receptors trk and p75 and of the major NGF si...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Powers JF,Shahsavari M,Tsokas P,Tischler AS

    更新日期:1999-01-01 00:00:00