Abstract:
:The bursa of Fabricius of the chicken is known to be both a primary lymphoid organ and a secondary lymphoid tissue. Bursal follicles are equipped with antigen-trapping follicle-associated epithelium. However, bioactive antigens such as protein and bacteria have not been detected in the bursal parenchyma. By immunoperoxidase staining with a polyspecific antibody (Ab) against Escherichia coli, we detected aggregated E. coli antigens in the medulla of bursal follicles after hatching. The distribution of aggregated E. coli antigens is restricted to the medulla of bursal follicles. The antigens are not found in the spleen or the parenchyma of the caecal tonsil. The bursa is thus a trapping site for E. coli antigens from the external environment. Furthermore, two-color immunostaining clarified that these antigens form immune complexes with maternal IgG (MIgG) and are retained by reticular cells. Additionally, immune complexes in the bursa were shown to induce the rapid development of serum IgM Ab for indigenous E. coli. Our results suggest that immune complexes of MIgG and environmental antigens in the medulla of bursal follicles exert positive effects on B-cell differentiation in the bursa in situ.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Sonoda K,Noguchi K,Ekino Sdoi
10.1007/s00441-013-1701-zsubject
Has Abstractpub_date
2013-12-01 00:00:00pages
813-21issue
3eissn
0302-766Xissn
1432-0878journal_volume
354pub_type
杂志文章abstract::Many noctuid moth species perceive ultrasound via tympanic ears that are located at the metathorax. Whereas the neural processing of auditory information is well studied at the peripheral and first synaptic level, little is known about the features characterizing higher order sound-sensitive neurons in the moth brain....
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-013-1749-9
更新日期:2014-02-01 00:00:00
abstract::We have recently identified a tachykinin-related peptide (AmTRP) from the mushroom bodies (MBs) of the brain of the honeybee Apis mellifera L. by using direct matrix-assisted laser desorption/ionization with time-of-flight mass spectometry and have isolated its cDNA. Here, we have examined prepro-AmTRP gene expression...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0865-y
更新日期:2004-05-01 00:00:00
abstract::We have previously shown that mice deficient in the gene for the myelin-associated glycoprotein (MAG) develop normal myelin in the peripheral nerves, but show axon and myelin degeneration at eight months of age, suggesting that MAG is involved in the maintenance of axon-Schwann cell integrity. The search for molecules...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050727
更新日期:1997-01-01 00:00:00
abstract::Extracellular matrix (ECM) plays a dynamic role during tissue development and re-growth. Body part regeneration efficiency relies also on effective ECM remodelling and deposition. Among invertebrates, echinoderms are well known for their striking regenerative abilities since they can rapidly regenerate functioning com...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03201-0
更新日期:2020-09-01 00:00:00
abstract::Myosin and actin were localized by indirect immunofluorescence microscopy using specific antibodies prepared in rabbits against highly purified gizzard myosin and actin. A strong fluorescence staining with both antibodies was observed in rat corneal epithelial cells, anterior lens epithelial cells, rod inner segments,...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221771
更新日期:1977-07-19 00:00:00
abstract::Two populations of thymic lymphocytes from eight-week-old mice were separated based on the light scatter intensity they generated while passing through a flow cell analyser. The two populations were subsequently studied morphologically and analysed for the relative amount of DNA present in each cell. Cells having a lo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234855
更新日期:1979-09-01 00:00:00
abstract::The electric organs of embryonic Torpedo marmorata have been reacted with three cationic stains to evaluate the appearance and distribution of anionic sites. Ruthenium red, alcian blue and lysozyme were used at different pHs and found to react in a time-related manner to anionic components within the interelectrocyte ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214662
更新日期:1987-10-01 00:00:00
abstract::The present study attempts to elucidate the role of TRPV1 cation channel receptor on primary repair in an incision-wounded mouse cornea in vivo. Previous study revealed that blocking TRPV1 suppressed myofibroblast formation and expression of transforming growth factor β1 (TGFβ1) in cultured keratocytes or ocular fibro...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2878-y
更新日期:2018-11-01 00:00:00
abstract::The desert locust Schistocerca gregaria is a major agricultural pest in North Africa and the Middle East. As such, it has been intensely studied, in particular with respect to population dynamics, sensory processing, feeding behavior flight and locomotor control, migratory behavior, and its neuroendocrine system. Bein...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2844-8
更新日期:2018-10-01 00:00:00
abstract::Generally, the CRF-like activity of vasopressin is studied in experiments involving adrenalectomy and corticosteroid replacement. In order to avoid this complex type of stress, male and female (diestrus, estrus) rats were exposed to 5 min to immobilization stress and sacrificed 5, 15, and 30 min thereafter. After a su...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00209276
更新日期:1978-05-29 00:00:00
abstract::The genes encoding transmembrane glycoproteins of the cadherin family, i.e., the Ca(2+)-dependent cell-cell adhesion molecules, are typically expressed in cell-type- or cell-lineage-specific patterns. One of them, vascular endothelial (VE)-cadherin, is widely considered to be specific for vascular endothelia in which ...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-008-0718-1
更新日期:2009-01-01 00:00:00
abstract::We conducted an immunoelectron-microscopic study for histamine (HA) in the enterochromaffin-like (ECL) cells of normal rats and rats given alpha-fluoromethylhistidine (alpha-FMH, 3 mg/kg per hour) via osmotic minipumps over a period of 24 h. The indirect immunoperoxidase procedure utilized a mouse monoclonal antibody ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100448
更新日期:2001-11-01 00:00:00
abstract::Voltage-gated Na+ channels are expressed by highly metastatic MAT-LyLu cells, but not by poorly metastatic AT-2 cells, derived from the rodent Dunning model of prostatic cancer. We have investigated the possible involvement of these channels in the morphological development of the cells. Incubation of both the MAT-LyL...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051256
更新日期:1999-03-01 00:00:00
abstract::The therapeutic potency of delivered mesenchymal stem cells (MSCs) in tissue engineering applications may be improved by priming cells toward a differentiated state via coculture with native, differentiated cells prior to implantation; however, there is a lack of understanding in what may be the most efficacious metho...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1265-8
更新日期:2012-03-01 00:00:00
abstract::The colocalization of immunoreactivities to substance P and calcitonin gene-related peptide (CGRP) in nervous structures and their correlation with other peptidergic structures were studied in the stellate ganglion of the guinea pig by the application of double-labelling immunofluorescence. Three types of fibre were d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318563
更新日期:1993-06-01 00:00:00
abstract::Numerous macrophages were found aggregated in the lamina propria at the tips of villi in the small intestine of guinea pigs. These macrophages extended their pseudopodia into the epithelial lining and internalized fragments of effete enterocytes in their phagosomes. The epithelium of the villus tips was found to be in...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF02913723
更新日期:1993-03-01 00:00:00
abstract::We used immunohistochemistry to identify cells present in pituitary allografts in the hamster. Hypophyses removed from neonatal hamsters or adenohypophyses removed from adult females were placed beneath renal capsules of hypophysectomized adult females. Serum PRL, LH, and GH concentrations were measured at two, five a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215467
更新日期:1988-01-01 00:00:00
abstract::Estradiol injections increase serum level of calcium, amino acid, glucose, protein, ammonia and creatinine in immature Epinephelus akaara, and also increase levels of total lipid, cholesterol, phospholipid and esterified fatty acids. Hepatic protein, glycogen and lipid concentrations also rise after estradiol treatmen...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217235
更新日期:1984-01-01 00:00:00
abstract::1,25-Dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 have antagonistic effects on the acellular bone of the tilapia Sarotherodon mossambicus. 1,25-Dihydroxyvitamin D3 inhibits the activity of the lining osteoblasts. Prolonged administration leads to demineralization of the bone matrix. Injection of 24,25-dihydroxyvi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00206270
更新日期:1983-01-01 00:00:00
abstract::In an ultrastructural study on the spermiogenesis of the rainbow trout (Salmo gairdneri R.) four spermatogenetic stages were identified. In young round spermatids, the nuclear chromatin was first heterogeneous (euchromatin and heterochromatin). Subsequently, it became more homogeneous and started to condense in the fo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00238295
更新日期:1983-01-01 00:00:00
abstract::Nerve fibers connecting the brain with the pineal gland of the Mongolian gerbil (central pinealopetal fibers) were investigated by means of light and electron microscopy. Several myelinated fibers penetrate from the brain into the deep pineal gland, extend further into the pineal stalk and continue to the superficial ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213804
更新日期:1983-01-01 00:00:00
abstract::The extracellular matrix (ECM) acts as a critical factor during morphogenesis. Because the organization of the ECM directly influences the structure of tissues and organs, a determination of the way that ECM organization is regulated should help to clarify morphogenesis. We have analyzed the assembly of Del1, an ECM p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0456-9
更新日期:2007-10-01 00:00:00
abstract::Antibodies against laminin (LN), fibronectin (FN), collagen type IV (Col IV), neural cell adhesion molecule (N-CAM), T-61 antigen, actin, tubulin and neurofilament protein were injected into the eyes of quail embryos (Coturnix coturnix japonica) of different ages. Twenty h after injection, the heads of the embryos wer...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217320
更新日期:1987-09-01 00:00:00
abstract::The young of the aquatic Australian frog, Rheobatrachus silus (Leptodactylidae) develop from eggs to juvenile frogs in the mother's stomach. During brooding the stomach expands greatly and becomes very thin walled. Transmission electron microscopy showed that the distension of the stomach was accompanied by a severe d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222194
更新日期:1983-01-01 00:00:00
abstract::New genome-editing approaches, such as the CRISPR/Cas system, have opened up great opportunities to insert or delete genes at targeted loci and have revolutionized genetics in model organisms like the zebrafish. The Cre-loxp recombination system is widely used to activate or inactivate genes with high spatial and temp...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2798-x
更新日期:2018-04-01 00:00:00
abstract::Duck muscle spindles show a large outer capsule enclosing a number of intrafusal muscle fibres which are individually encircled by an inner capsule. The outer capsule consists of a multilayer of 4-6 flattened cells with elongated nuclei, and are usually lined by a basement membrane. They resemble and are linked with p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234400
更新日期:1980-01-01 00:00:00
abstract::The ultrastructure of the contractile apparatus of the rat soleus muscle during the course of denervation atrophy was investigated. It was found that the ratio of thin the thick filaments increased in myofibrils of atrophying muscle fibers. Elevation of the ratio was observed as early as the second day after denervati...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216767
更新日期:1981-01-01 00:00:00
abstract::Calbindin is a calcium-binding protein, commonly found in certain subpopulations of the enteric nervous system in mammals. Recently, calbindin-immunoreactive enteric neurons have also been demonstrated in shorthorn sculpin (Myoxocephalus scorpius). In the present study, calbindin immunoreactivity has been investigated...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1135-4
更新日期:2011-04-01 00:00:00
abstract::Teleost fish exhibit extraordinary cognitive skills that are comparable to those of mammals and birds. Kin recognition based on olfactory and visual imprinting requires neuronal circuits that were assumed to be necessarily dependent on the interaction of mammalian amygdala, hippocampus, and isocortex, the latter being...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-020-03378-4
更新日期:2021-01-30 00:00:00
abstract::Gastrin stimulates gastric acid secretion by acting on the cholecystokinin B/gastrin receptor (CCK-BR). The localization of this receptor at the cellular level showed conflicting results in animal studies and has not been described in man by immunohistochemistry. The aim of the present study is to characterize the pre...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004419900114
更新日期:2000-02-01 00:00:00