Calretinin and calbindin in the retina of the developing chick.

Abstract:

:Calretinin and calbindin-D28k are two calcium-binding proteins that are present in largely different sets of nerve cells in the central nervous system. Their appearance during development of the chick retina was studied by immunohistochemistry and Western blots. The patterns are mature one day before hatching. Each cell type acquires its characteristic calcium-binding protein several days after its differentiation has started, but in most cases before morphological maturation is complete. There is also an early phase of calbindin immunoreactivity in many immature amacrine cells, and of calretinin immunoreactivity in the presumptive photoreceptor layer, suggesting that these proteins may have distinct functions in differentiating cells.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Ellis JH,Richards DE,Rogers JH

doi

10.1007/BF00313956

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

197-208

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

264

pub_type

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