Abstract:
:Calretinin and calbindin-D28k are two calcium-binding proteins that are present in largely different sets of nerve cells in the central nervous system. Their appearance during development of the chick retina was studied by immunohistochemistry and Western blots. The patterns are mature one day before hatching. Each cell type acquires its characteristic calcium-binding protein several days after its differentiation has started, but in most cases before morphological maturation is complete. There is also an early phase of calbindin immunoreactivity in many immature amacrine cells, and of calretinin immunoreactivity in the presumptive photoreceptor layer, suggesting that these proteins may have distinct functions in differentiating cells.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Ellis JH,Richards DE,Rogers JHdoi
10.1007/BF00313956subject
Has Abstractpub_date
1991-05-01 00:00:00pages
197-208issue
2eissn
0302-766Xissn
1432-0878journal_volume
264pub_type
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