Abstract：
:The ability of levamisole (LVS) to correct the effect of thymectomy on splenic T-cell population in Bufo bufo larvae was tested. Using the nonspecific acid alpha-naphthyl acetate esterase (ANAE) technique, the T-lymphocytes displayed a characteristic reddish brown spot (T-pattern). The total number of white cells per spleen and the number of T-pattern cells per 100 splenic white cells were determined. In addition, differential counts of the T-patterns were made on the basis of the size of their spots. Thymectomized larvae in comparison to sham-operated larvae possessed a lower total number of splenic white cells with a similar proportion of T-pattern cells, but a lower proportion of cells with a large T-pattern. After seven days of LVS treatment, the thymectomized larvae showed an increased total number of splenic white cells and an increased proportion of cells with a large T-pattern, both data falling within normal limits. The effect of LVS appeared marked in thymectomized larvae, but was slight or absent in sham-operated larvae. Differential counts of the large T-pattern cells, based on the size of ANAE reaction product, showed the capacity of LVS to stimulate T-cell maturation. It was concluded that LVS induced proliferation and differentiation of splenic T-cells and that the different sizes of T-pattern reaction represent different maturational stages of T-cells.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Garavini C,Rossini MC,Mantovani Bdoi
10.1007/BF00204789subject
Has Abstractpub_date
1982-01-01 00:00:00pages
595-600issue
3eissn
0302-766Xissn
1432-0878journal_volume
227pub_type
杂志文章abstract：:Recent studies demonstrated the expression of the insulin receptor (InsR) and its functional interaction with the transient receptor potential vanilloid type 1 receptor (TRPV1) in primary sensory neurons (PSNs). The present study was undertaken to reveal the target-specific expression of the InsR and its co-localizati...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2868-0
更新日期：2018-11-01 00:00:00
abstract：:Mesenchymal stem cells (MSCs) are increasingly being reported as occurring in a variety of tissues. Although MSCs from human bone marrow are relatively easy to harvest, the isolation of rodent MSCs is more difficult, thereby limiting the number of experiments in vivo. To determine a suitable cell source, we isolated r...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0308-z
更新日期：2007-03-01 00:00:00
abstract：:The ontogeny of two gonadotropin-releasing-hormone (GnRH) systems, salmon GnRH (sGnRH) and chicken GnRH-II (cGnRH-II), was investigated in zebrafish (Danio rerio). In situ hybridization (ISH) first detected sGnRH mRNA-expressing cells at 1 day post-fertilization (pf) anterior to the developing olfactory organs. Subseq...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0279-0
更新日期：2007-02-01 00:00:00
abstract：:We report here on cholinergic neurons in the rat hippocampal formation that were identified by immunocytochemistry employing a monoclonal antibody against choline acetyltransferase (ChAT), the acetylcholine-synthesizing enzyme. In general, ChAT-immunoreactive cells were rare, but were observed in all layers of the hip...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215891
更新日期：1986-01-01 00:00:00
abstract：:The medial preoptic nucleus is a sexually dimorphic structure whose cytoarchitecture, afferent and efferent connections, and functions have been previously described. No detailed ultrastructural study has, however, been performed to date. Here we describe the ultrastructural organization of this important preoptic str...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318164
更新日期：1995-03-01 00:00:00
abstract：:Calcitonin gene-related peptide (CGRP) was found extensively in the small intestine of both non-mammalian and mammalian vertebrates using radioimmunoassay and immunocytochemistry. By radioimmunoassay, the levels of CGRP in rats, mice, chickens, bullfrogs and rainbow trout were found to range from 91.5 to 419.1 ng/g ti...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00223142
更新日期：1989-10-01 00:00:00
abstract：:The ontogeny of protein gene product 9.5 (PGP 9.5), serotonin (5-HT), calcitonin gene-related peptide (CGRP), and calcitonin (CT) immunoreactivity was evaluated in small-granule endocrine cells of hamster laryngotracheal epithelium from fetal day 11 to adulthood. Two centrifugal (proximal-to-distal) patterns of differ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305382
更新日期：1994-01-01 00:00:00
abstract：:Scanning electrom microscopy of the ventricular surface of the pars ventralis of the tuber cinereum of the frog Rana temporaria shows that it can be divided in (1) a dorsolateral area, characterized by the presence of very numerous large, solid, bulbous protrusions (2) a medial area, where the large bulbous structures...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231997
更新日期：1975-05-27 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217578
更新日期：1985-01-01 00:00:00
abstract：:An electron-microscopic study of the myotendinous portion of the diaphragm in the Wistar rat has shown that at the ends of muscle fibers, longitudinally oriented invaginations and peripheral furrows of the sarcolemma establish specialized contacts with individual sacs of the sarcoplasmic reticulum. The construction of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00251058
更新日期：1986-01-01 00:00:00
abstract：:The long nonmyelinated portion of the unipolar process of spinal ganglion cells resembles in many instances the perikaryon and is characterized by the following structural pecularities: 1. The surface membrane displays numerous invaginations and evaginations, which interdigitate with folds of the investing satellite c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222438
更新日期：1976-01-27 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218494
更新日期：1975-11-19 00:00:00
abstract：:The objectives of these studies were to determine if (1) hypertrophy-stimulated myogenic regulatory factor (MRF) mRNA increases occur in the absence of proliferating satellite cells, and (2) acute hypertrophy occurs without satellite cell proliferation. Adult and aged quails were exposed to 0 or 2500 Rads gamma irradi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051314
更新日期：1999-06-01 00:00:00
abstract：:R*-cells of the digestive gland of Carcinus maenas have been investigated functionally and morphologically. A comparison of the capacity of separated cell suspensions to synthesize glycogen gave support to the hypothesis that R and R* cells belong to the same cell line. The unexpected observation of R* cells in gastri...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318696
更新日期：1992-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051358
更新日期：1999-08-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2418-6
更新日期：2016-10-01 00:00:00
abstract：:A gelsolin-related protein was isolated from seminal vesicles of the annelid Lumbricus terrestris. Compared with the isoforms of the gelsolin-related protein previously found in the muscle of the annelid body wall, the isolated protein was assigned to the first isoform (EWAM-P1) because of its electrophoretic mobility...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0561-9
更新日期：2008-04-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050897
更新日期：1997-09-01 00:00:00
abstract：:The cellular localization of renin was examined in the kidneys of some amphibians of the genus Bufo by immunoperoxidase and immunofluorescence techniques with an antiserum to renin isolated from the submandibular gland of the mouse. Immunoreactivity could be demonstrated in the media cells of the afferent arterioles (...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219248
更新日期：1985-01-01 00:00:00
abstract：:The innervation pattern of distal muscle fibers of the opener muscle of walking legs of crayfish (Astacus leptodactylus) was investigated using methylene-blue staining, cobalt infiltration, and electron microscopy. A quantitative analysis of the entire innervation of single muscle fibers was attempted. It was found th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00213750
更新日期：1982-01-01 00:00:00
abstract：:It is known that human and animal fibroblasts are able to induce the retraction of a fibrin clot. In the present study the correlation between (i) fibrin-fibroblasts during growth, (ii) the number of actin stress-lines in mouse fibroblasts during growth in culture, and (iii) the sensitivity of actin stress-lines to a ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218485
更新日期：1982-01-01 00:00:00
abstract：:The otoconia of Amphibia, especially of the frog Rana esculenta, were studied by X-ray diffraction and scanning electron microscopy (SEM). The SEM studies showed that the membranous labyrinth of Amphibia contains two populations of crystals, which can easily be distinguished by their forms. The X-ray diffraction data ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222230
更新日期：1983-01-01 00:00:00
abstract：:Drosophila melanogaster photoreceptors are highly polarized cells and their plasma membrane is organized into distinct domains. Zonula adherens junctions separate a smooth peripheral surface, the equivalent of the basolateral surface in other epithelial cells, from the central surface (approximately equal to apical su...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000195
更新日期：2000-05-01 00:00:00
abstract：:An electron microscopical investigation of the pineal gland of the adult noctule bat revealed the presence of some peculiar ciliary derivatives, similar to the club-shaped outer segment of rudimentary photoreceptor cells in the pineal organ of nonmammalian vertebrates. The pinealocytes of population I can be classifie...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222058
更新日期：1977-07-26 00:00:00
abstract：:The pituitary gland is first evident in rainbow trout two weeks before hatching. Differentiation of prolactin and ACTH cells is not marked until 3-4 days after hatching when the follicular arrangement of the prolactin cells become apparent. There is no difference in the time of development of either prolactin or ACTH ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00209283
更新日期：1978-05-29 00:00:00
abstract：:Vesicular transport involves SNARE (soluble- N-ethylmaleimide-sensitive-factor-attachment-protein-receptor) proteins on transport vesicles and on target membranes. Syntaxin 13 is a SNARE enriched in brain, associated with recycling endosomes; its overexpression in PC12 cells promotes neurite outgrowth. This suggests a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0600-5
更新日期：2002-08-01 00:00:00
abstract：:In cattle, the oviduct plays a major role in the reproductive process; however, molecular control of oviduct receptivity to the embryo is poorly understood. A model for receptivity based on size of the pre-ovulatory follicle (POF) was used to compare oviductal morphology, cellular proliferation, and candidate transcri...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-017-2666-0
更新日期：2017-11-01 00:00:00
abstract：:Variations in gene expression patterns represent a powerful source of evolutionary innovation. In a rodent living about 70 million years ago, a genomic accident led an immune formyl peptide receptor (FPR) gene to hijack a vomeronasal receptor regulatory sequence. This gene shuffling event forced an immune pathogen sen...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03393-5
更新日期：2021-01-16 00:00:00
abstract：:The alimentary system of Habrotrocha rosa is composed of the alimentary channel, five digestive glands and another gland which is in close relation to the intestinal syncytium. After the present investigation, the alimentary channel can be divided into sections which clearly differ from each other, these are: oral cav...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00209138
更新日期：1978-06-08 00:00:00
abstract：:Type-A spermatogonia can be found in different locations throughout the germinal epithelium of human seminiferous tubules. Generally they represent the population of germ cells adjacent to the basal lamina, but under special conditions they may be located in the adluminal compartment. This aberrant location is found n...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216510
更新日期：1984-01-01 00:00:00
