Abstract:
:Thin sections after bile duct ligation showed that the depth of tight junctions appeared to increase and that the distance between individual punctate contacts appeared to become irregular and wider than in controls. The freeze fracture replicas clearly demonstrated these changes in the tight junction morphology. Changes were noted most conspicuously in the tight junction three weeks after ligation. Measurements of the junctional morphology in control and ligated specimens showed that the junctional depth had increased two fold in the latter, whereas the number of strands had scarcely changed. Lanthanum tracer experiments showed that the tight junctions did not permit the passage of the tracer in normal nor ligated rats. It was concluded that the mechanism of obstructive jaundice could not be related to changes in junctional morphology causing increased junctional permeability.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Koga A,Todo Sdoi
10.1007/BF00236724subject
Has Abstractpub_date
1978-12-28 00:00:00pages
267-76issue
2eissn
0302-766Xissn
1432-0878journal_volume
195pub_type
杂志文章abstract::Periodontal regeneration requires the coordinated movement and differentiation of several cell types in order to re-establish the cementum, periodontal ligament (PDL), and alveolar bone. Cells in culture are often used as model systems for mature tissues, although they may represent expanded progenitor cell population...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-006-0282-5
更新日期:2007-01-01 00:00:00
abstract::Growing numbers of translational genomics studies are based on the highly efficient and versatile zebrafish (Danio rerio) vertebrate model. The increasing types of zebrafish models have improved our understanding of inherited kidney diseases, since they not only display pathophysiological changes but also give us the ...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-017-2593-0
更新日期:2017-07-01 00:00:00
abstract::The submandibular gland (SMG) of newborn mice has no mature acini but has the rudiments of acini called terminal tubules (TT). The TT are composed of TT cells with dark secretory granules and proacinar cells with lighter secretory granules, the latter being considered the immediate precursor of mature acinar cells. TT...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03205-w
更新日期:2020-08-01 00:00:00
abstract::Based on its proven anabolic effects on bone in osteoporosis patients, recombinant parathyroid hormone (PTH(1-34)) has been evaluated as a potential therapy for skeletal repair. In animals, the effect of PTH(1-34) has been investigated in various skeletal repair models such as fractures, allografting, spinal arthrodes...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-011-1188-4
更新日期:2012-03-01 00:00:00
abstract::Differentiated nongranulated (folliculo-stellate) cells were observed in the centre and periphery of the cords of cells in the pars distalis of the adult tammar wallaby (Macropus eugenii). The nongranulated cells formed follicles containing a small lumen: the cell apices were joined by junctional complexes including z...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00210898
更新日期:1982-01-01 00:00:00
abstract::Previous light-microscopic and ultra-immunohistochemical tracer studies revealed the existence of an independent local immune response of the simian oral mucosa. This local response is attributed to the presence of minor salivary gland (MSG) duct-related lymphoid tissue. Semithin sections from a total of 263 Epon-embe...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217578
更新日期:1985-01-01 00:00:00
abstract::When stimulated by the feeding of ethylenethiourea for a period of 6 months, dog thyroid glands increased to approximately 30 times their normal size. Not only follicular cells but also C cells had hyperplastic and hypertrophic features, compared with normal controls there was in the C cells a marked decrease in secre...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214684
更新日期:1982-01-01 00:00:00
abstract::In the intestine of the filtering zooids of B. schlosseri three segments can be distinguished. In the intermediate segment the epithelium, which is encrusted by the ampullae of the pyloric gland, shows marked aspects of alteration. In the proximal and distal segments, ciliated mucous, vacuolated and endocrine-like cel...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219771
更新日期:1977-08-26 00:00:00
abstract::Ultrastructural investigations showed that development and maintenance of smooth muscle was similar in control and aneurogenic amphibian larvae. This applies to both multi-unit and unitary smooth muscles. The gut musculature displayed a regional variation in smooth muscle morphology and a variety of intermuscular appo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00227048
更新日期:1976-02-12 00:00:00
abstract::In developing bioassays for estrogenic effects, vitellogenin (Vtg) induction and zona radiata protein (Zr-protein) induction in males and juveniles of oviparous vertebrates have been used as sensitive biomarkers for estrogenicity. Nonylphenol (NP) produces similar and parallel expression patterns of Vtg and Zr-protein...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0543-y
更新日期:2008-03-01 00:00:00
abstract::The localization of inhibin alpha-subunit in the human testis was studied at the light- and electron-microscope level with immunostaining techniques. Antibodies against specific fragments of porcine and human inhibin alpha-subunits were utilized. At light microscopy, inhibin alpha-subunit immunoreactivity was detected...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00319612
更新日期:1992-08-01 00:00:00
abstract::Taste buds and the peripheral nerves innervating them are two important components of the peripheral gustatory system. They require appropriate connections for the taste system to function. Neurotrophic factors play crucial roles in the innervation of peripheral sensory organs and tissues. Both brain-derived neurotrop...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-009-0833-7
更新日期:2009-09-01 00:00:00
abstract::Light and electron microscopic studies, including the use of the vital dyes trypan blue and acridine orange, indicate that the topical application of precocene II rapidly triggers degenerative processes in the corpora allata (CA) leading within a few days to the virtual disappearance of the parenchymal cells of these ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234326
更新日期:1979-11-01 00:00:00
abstract::A quantitative evaluation of putative amino acid neurotransmitters in sea pansy polyps by high-performance liquid chromatography indicates that the taurine content exceeds that of other amino acids by a 100-fold. The cellular source of this taurine was investigated by immunohistochemistry with two polyclonal antisera ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050800
更新日期:1997-04-01 00:00:00
abstract::Rats were injected with liposomes containing iodixanol (CTP10 Injection; 100 mg iodine per kg body weight) followed by a second injection of 125I-tyramine-cellobiose-albumin microspheres. The amounts of phagocytosed and degraded labelled albumin in liver were measured. A reduced uptake and degradation of albumin micro...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000229
更新日期:2000-06-01 00:00:00
abstract::An ectodermal network of nerve cells has been observed in the echinopluteus. It seems to connect the ectodermal cell bodies with each other and with deeper parts of the nerve system. Together with the neurohumour containing parts of the ventral and oral ciliated bands, the nerve cells probably provide the larva with t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219793
更新日期:1977-04-07 00:00:00
abstract::With an indirect immunofluorescence technique and an antiserum raised against synthetic LHRH, immunofluorescent granules were observed in fine radially oriented fibres in the palisade layer of the zoma externa in both the anterior and the posterior divisions of the median eminence in the greenfinch. There was no speci...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223264
更新日期:1975-09-16 00:00:00
abstract::This study describes the morphology and distribution of setae on the lateral and medial flagella of the antennules of the spiny lobster Panulirus argus in an effort to identify antennular chemoreceptors in addition to the well-studied aesthetasc chemosensilla. Setae were examined using light and electron microscopy, a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100377
更新日期:2001-06-01 00:00:00
abstract::Thyroid glands of 7 to 21 day-old chick embryos were examined by electron microscopy using freeze-fracture and thin-section preparations. The primitive follicle lumen first appears between two adjacent epithelial cells in 8 day-old embryos, and is formed in the region of a focal tight junction (macula occludens). The ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234830
更新日期:1979-04-30 00:00:00
abstract::Immunocytochemistry was used to determine if photoperiod and/or sex have any effect on the pattern of the luteinizing hormone-releasing hormone (LHRH) system in the brain of the Japanese quail. Immunopositive perikarya were found within three major areas of the brain: the rostral paraolfactory lobe, the preoptic, and ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222289
更新日期:1988-08-01 00:00:00
abstract::We have recently reported that Sox2-expressing pituitary stem/progenitor cells contact each other via a tight-junction protein CAR to form stem/progenitor cell niches in the marginal cell layer facing the lumen and in the clusters scattered in the parenchyma of the anterior lobe. However, the microenvironment of the n...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-2054-y
更新日期:2015-03-01 00:00:00
abstract::Endothelial repair to reestablish structural integrity following wounding is a complex process. Since the actin cytoskeleton undergoes specific changes in distribution as quiescent endothelial cells switch to activated migrating cells over a 6-h period following wounding (Lee et al. 1996), we studied tyrosine phosphor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051370
更新日期:1999-09-01 00:00:00
abstract::Uptake of uteroglobin (UGL) by day-6 rabbit blastocysts and the intracellular fate of this protein were studied by light- and electron-microscopic autoradiography, immunocytochemistry and acid-phosphatase cytochemistry. UGL, labelled with N-succinimidyl-(2-3-3H)-propionate, was administered to embryos in vitro for 25 ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00305254
更新日期:1990-12-01 00:00:00
abstract::The existence of a neural crest cell migration pathway from occipital levels of the hindbrain into the heart was suspected in mammalian embryos because it had previously been identified in avian embryos and because the Di George anomaly, an association between craniofacial and cardiac malformations, is most easily exp...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00338048
更新日期:1992-04-01 00:00:00
abstract::Colonies of the ascidian Botryllus schlosseri undergo recurrent generation changes in which adult zooids are gradually resorbed and replaced by new blastogenic generations. During these periods, known as take-over phases, programmed cell death, which, on the basis of morphological analysis is ascribed to apoptosis, oc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0738-9
更新日期:2003-06-01 00:00:00
abstract::Besides its function at cholinergic synapses, acetylcholinesterase (AChE) exerts structural functions on neural differentiation, independent of its enzymatic activity. To elucidate such functions, we have previously heterologously expressed AChE in histotypic retinal reaggregates, revealing strong effects on their his...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100444
更新日期:2001-11-01 00:00:00
abstract::The circadian timing system is a neural network consisting of the hypothalamic suprachiasmatic nucleus, aided by the retina, other hypothalamic nuclei, autonomic regions of the spinal cord, sympathetic ganglia and the pineal gland. Extensive studies conducted over the last two decades have unravelled the principal ite...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s004410050652
更新日期:1996-09-01 00:00:00
abstract::Freeze-fracture replicas of the rat corpus callosum revealed prominent junctional strands in fractured cell membranes of the somata of oligodendrocytes. The junctional strands were characterized by an elaborate system of straight or slightly undulating rows of linear aggregates of particles or ridges in the P face and...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220534
更新日期:1977-10-21 00:00:00
abstract::When tissues are processed for electron microscopy by conventional methods, such as glutaraldehyde fixation followed by rapid dehydration in acetone, basement membranes show two main layers: the electron-lucent "lamina lucida". (or rara) and the electron-dense "lamina densa". In an attempt to determine whether this su...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00304610
更新日期:1993-07-01 00:00:00
abstract::Osteogenic differentiation is a tightly regulated process realized by progenitor cell osteoblasts. Notch signaling pathway plays a critical role in skeletal development and bone remodeling. Controversial data exist regarding the role of Notch activation in promoting or preventing osteogenic differentiation. This study...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-03130-7
更新日期:2020-01-01 00:00:00